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List of works by Julian Little

"They Should Be Asking Us": A Qualitative Decisional Needs Assessment for Women Considering Cervical Cancer Screening

scientific article published on 01 January 2018

A P3G generic access agreement for population genomic studies

scientific article (publication date: May 2013)

A genetic variant in the placenta-derived MHC class I chain-related gene A increases the risk of preterm birth in a Chinese population

scientific article published on September 2017

A meta-analysis of observational studies of the association between chronic occupational exposure to lead and amyotrophic lateral sclerosis

scientific article

A network of investigator networks in human genome epidemiology

scientific article

A qualitative study of provider perspectives of structural barriers to cervical cancer screening among first nations women

scientific article

A road map for efficient and reliable human genome epidemiology

scientific article published on January 2006

A simple model to predict risk of gestational diabetes mellitus from 8 to 20 weeks of gestation in Chinese women

scientific article published on 19 July 2019

A vision for chronic disease prevention intervention research: report from a workshop

scientific article published on 17 April 2014

APACC, a French prospective study on aspirin efficacy in reducing colorectal adenoma recurrence: design and baseline findings

scientific article (publication date: August 2001)

Accurate prediction of gestational age using newborn screening analyte data

scientific article

Achieving the "triple aim" for inborn errors of metabolism: a review of challenges to outcomes research and presentation of a new practice-based evidence framework

scientific article published on 06 December 2012

Addressing the challenges of cleft lip and palate research in India

scientific article

After-effects reported by women having follow-up cervical cytology tests in primary care: a cohort study within the TOMBOLA trial

scientific article

Alcohol consumption and the risk of breast cancer among BRCA1 and BRCA2 mutation carriers

scientific article published on 12 June 2010

An epidemiologic assessment of genomic profiling for measuring susceptibility to common diseases and targeting interventions

scientific article published on January 2004

An international case-control study of adult diet and brain tumor risk: a histology-specific analysis by food group

scientific article published on March 2009

Antenatal therapeutic drug exposure and fetal/neonatal tumours: review of 89 cases ⬇️

scientific article published on January 1, 1998

Assessment of cumulative evidence on genetic associations: interim guidelines

scientific article published on 26 September 2007

Assessment of systematic effects of methodological characteristics on candidate genetic associations

Association between a common missense variant in LOXL3 gene and the risk of non-syndromic cleft palate

scientific article published on 11 June 2018

Association between newborn screening analyte profiles and infant mortality

scientific article published on 21 May 2019

Association between newborn screening analytes and hypoxic ischemic encephalopathy

scientific article published on 31 October 2019

Association of Melanocortin-1 Receptor Variants with Pigmentary Traits in Humans: A Pooled Analysis from the M-Skip Project ⬇️

scientific article published on 29 May 2016

Association of maternal risk factors with the recent rise of neural tube defects in Canada

scientific article published on 01 March 2019

Associations between two common variants C677T and A1298C in the methylenetetrahydrofolate reductase gene and measures of folate metabolism and DNA stability (strand breaks, misincorporated uracil, and DNA methylation status) in human lymphocytes in

scientific article published in September 2004

Attitudes of undergraduate university women towards HPV vaccination: a cross-sectional study in Ottawa, Canada

article

Bias in the case-only design applied to studies of gene-environment and gene-gene interaction: a systematic review and meta-analysis

scientific article published on 04 July 2011

Bridging the gap between science and policy: an international survey of scientists and policy makers in China and Canada

scientific article published on 6 February 2016

CYP17 and breast cancer: no overall effect, but what about interactions?

scientific article

Cancer risk in children and adolescents with birth defects: a population-based cohort study

scientific article

Cell-Free DNA-Based Non-invasive Prenatal Screening for Common Aneuploidies in a Canadian Province: A Cost-Effectiveness Analysis

scientific article published on 04 August 2017

Characteristics and Workload of Pediatricians in China

scientific article published on 01 July 2019

Characterization of IGF-II isoforms in binge eating disorder and its group psychological treatment

scientific article

Child and family experiences with inborn errors of metabolism: a qualitative interview study with representatives of patient groups

scientific article

Childhood Cancer and Neural Tube Defects ⬇️

scientific article published on November 1, 1997

Citizens' values regarding research with stored samples from newborn screening in Canada

scientific article published on 16 January 2012

Clinical utility of cancer family history collection in primary care

scientific article published on April 2009

Colon Cancer and Genetic Variation in Folate Metabolism: The Clinical Bottom Line ⬇️

scientific article published on November 1, 2003

Colorectal cancer and genetic polymorphisms of CYP1A1, GSTM1 and GSTT1: a case-control study in the Grampian region of Scotland

scientific article published in November 2006

Colorectal neoplasia and genetic polymorphisms associated with folate metabolism

scientific article

Community-randomised controlled trial embedded in the Anishinaabek Cervical Cancer Screening Study: human papillomavirus self-sampling versus Papanicolaou cytology

scientific article published on 08 October 2016

Comparing alternative design options for chronic disease prevention interventions.

scientific article

Comparison of first-tier cell-free DNA screening for common aneuploidies with conventional publically funded screening

scientific article

Correction: Characterization of IGF-II Isoforms in Binge Eating Disorder and Its Group Psychological Treatment.

scientific article published on 15 January 2014

Correction: Defining the genetic susceptibility to cervical neoplasia-A genome-wide association study.

scientific article published in March 2018

Cyclooxygenase-2 expression and recurrence of colorectal adenomas: effect of aspirin chemoprevention

scientific article published in May 2010

Daily soluble aspirin and prevention of colorectal adenoma recurrence: one-year results of the APACC trial

scientific article (publication date: August 2003)

Data Safe Havens in health research and healthcare

scientific article

DataSHIELD: resolving a conflict in contemporary bioscience--performing a pooled analysis of individual-level data without sharing the data

scientific article (publication date: October 2010)

Defining the genetic susceptibility to cervical neoplasia-A genome-wide association study

scientific article published on 14 August 2017

Determinants of neurological disease: Synthesis of systematic reviews.

scientific article

Development and field testing of a tool to elicit women's preferences among cervical cancer screening modalities

scientific article published on 18 August 2019

Dietary flavonoid intake and colorectal cancer: a case-control study

scientific article published on 7 September 2009

Disruption of an AP-2alpha binding site in an IRF6 enhancer is associated with cleft lip

scientific article

Editorial: Updated guidance on human genome epidemiology (HuGE) reviews and meta-analyses of genetic associations

scientific article published on 26 August 2014

Effect of Folic Acid Food Fortification in Canada on Congenital Heart Disease Subtypes

scientific article published on August 2016

Effectiveness of individual-focused interventions to prevent chronic disease

scientific article published on September 2014

Effectiveness of stop smoking interventions among adults: protocol for an overview of systematic reviews and an updated systematic review

scientific article published on 19 January 2019

Effects of fat mass and obesity-associated (FTO) gene polymorphisms on binge eating in women with binge-eating disorder: The moderating influence of attachment style

scientific article published on 22 November 2018

Eliciting women's cervical screening preferences: a mixed methods systematic review protocol

scientific article published on 11 August 2016

Engaging Canadian First Nations Women in Cervical Screening through Education

scientific article published on 3 May 2016

Evaluating LINE-1 methylation in cleft lip tissues and its association with early pregnancy exposures.

scientific article published on 29 November 2017

Examining the Implementation of the Performance-Based Financing Equity Strategy in Improving Access and Utilization of Maternal Health Services in Cameroon: A Qualitative Study

scientific article published in 2022

Expectations and values about expanded newborn screening: a public engagement study

scientific article published on February 2013

Experiences of caregivers of children with inherited metabolic diseases: a qualitative study

scientific article published on 07 December 2016

External validation of postnatal gestational age estimation using newborn metabolic profiles in Matlab, Bangladesh

scientific article published on 19 March 2019

Factors associated with psychological distress following colposcopy among women with low‐grade abnormal cervical cytology: a prospective study within the Trial Of Management of Borderline and Other Low‐grade Abnormal smears (TOMBOLA) ⬇️

scientific article published on December 12, 2011

Family cancer history and risk of brain tumors in children: results of the SEARCH international brain tumor study

scientific article published on 16 February 2008

Family history and improving health

scientific article published on August 2009

Family history tools in primary care: does one size fit all?

scientific article

Family history: impact on coronary heart disease risk assessment beyond guideline-defined factors.

scientific article published on 25 July 2013

Fetal anticonvulsant syndromes and polymorphisms in MTHFR, MTR, and MTRR.

scientific article published in October 2007

Folate intake, markers of folate status and oral clefts: is the evidence converging?

scientific article

Folate, DNA stability and colo-rectal neoplasia

scientific article

Folic acid supplementation use and the MTHFR C677T polymorphism in orofacial clefts etiology: An individual participant data pooled-analysis

scientific article

Future risk of cancer in women who have children with birth defects

scientific article published on 12 July 2019

Gene-environment interactions and colorectal cancer risk: An umbrella review of systematic reviews and meta-analyses of observational studies

article

Genetic Interactions in Nonsyndromic Orofacial Clefts in Europe-EUROCRAN Study.

scientific article published on 20 December 2016

Genetic variation associated with the occurrence and progression of neurological disorders.

scientific article published on 3 October 2016

Genome-wide association studies for complex traits: consensus, uncertainty and challenges

scientific article

Genome-wide association studies, field synopses, and the development of the knowledge base on genetic variation and human diseases

scientific article

Genome-wide association studies, field synopses, and the development of the knowledge base on genetic variation and human diseases

HLA and KIR Associations of Cervical Neoplasia

scientific article published in 2018

Health Care for Mitochondrial Disorders in Canada: A Survey of Physicians

scientific article published on 01 November 2019

Health services use among children diagnosed with medium-chain acyl-CoA dehydrogenase deficiency through newborn screening: a cohort study in Ontario, Canada

article

Health-care providers' views on pursuing reproductive benefit through newborn screening: the case of sickle cell disorders.

scientific article published on 9 November 2011

How Credible Are Meta-Analyses of Risk Factors Based on Observational Studies for Amyotrophic Lateral Sclerosis A New Insight from an Umbrella Review

scientific article published on 12 April 2016

How many genes underlie the occurrence of common complex diseases in the population?

scientific article published on 25 July 2005

Human exposure to environmental contaminants and congenital anomalies: a critical review

scientific article

Human papillomavirus infection and anxiety: analyses in women with low-grade cervical cytological abnormalities unaware of their infection status

scientific article

Identification of risk factors associated with onset and progression of amyotrophic lateral sclerosis using systematic review and meta-analysis

scientific article

Identifying key knowledge needs for evidence-based conservation of wild insect pollinators: a collaborative cross-sectoral exercise

article

Impact of Dehydroepiandrosterone Sulfate on Newborn Leukocyte Telomere Length

scientific article published on 10 February 2017

Impact of alternative management policies on health-related quality of life in women with low-grade abnormal cervical cytology referred for colposcopy

scientific article published on 5 March 2013

Impact of post-colposcopy management on women's long-term worries: results from the UK population-based TOMBOLA trial

scientific article published on 16 September 2015

Incidental screen positive findings in a prospective cohort study in Matlab, Bangladesh: insights into expanded newborn screening for low-resource settings

Informing parents about expanded newborn screening: influences on provider involvement

article

Intermediate CAG repeat expansion in the ATXN2 gene is a unique genetic risk factor for ALS--a systematic review and meta-analysis of observational studies

scientific article

Is rigorous retrospective harmonization possible? Application of the DataSHaPER approach across 53 large studies

scientific article

Key characteristics of 86 agents known to cause cancer in humans

scientific article published on 22 October 2019

LINE-1 methylation in cleft lip tissues: Influence of infant MTHFR c.677C>T genotype

scientific article published on 20 June 2019

Leukaemia in young children living in the vicinity of nuclear power plants.

scientific article

Long-Term Worries after Colposcopy: Which Women Are at Increased Risk?

scientific article published on 4 June 2015

Low dose aspirin, COX-inhibition and chemoprevention of colorectal cancer

scientific article (publication date: 2005)

Low radon exposures and lung cancer risk: joint analysis of the Czech, French, and Beaverlodge cohorts of uranium miners.

scientific article published on 8 February 2019

MC1R variants as melanoma risk factors independent of at-risk phenotypic characteristics: a pooled analysis from the M-SKIP project. ⬇️

scientific article published on 14 May 2018

MC1R variants increased the risk of sporadic cutaneous melanoma in darker-pigmented Caucasians: a pooled-analysis from the M-SKIP project

scientific article

Management of women with low grade cytology: how reassuring is a normal colposcopy examination?

scientific article published on 20 June 2014

Maternal medication use and the risk of brain tumors in the offspring: the SEARCH international case-control study

scientific article

Measuring the psychosocial burden in women with low-grade abnormal cervical cytology in the TOMBOLA trial: psychometric properties of the Process and Outcome Specific Measure (POSM).

scientific article

Melanocortin-1 receptor, skin cancer and phenotypic characteristics (M-SKIP) project: study design and methods for pooling results of genetic epidemiological studies ⬇️

scientific article published on August 3, 2012

Mendelian randomisation: a new spin or real progress?

scientific article published on 01 September 2003

Metabolic Clinic Atlas: Organization of Care for Children with Inherited Metabolic Disease in Canada

scientific article published on 26 February 2015

Metabolic profiles derived from residual blood spot samples: A longitudinal analysis

Metabolomics of prematurity: analysis of patterns of amino acids, enzymes, and endocrine markers by categories of gestational age.

scientific article

Methods for meta-analyses of genome-wide association studies: critical assessment of empirical evidence

scientific article published on 16 March 2012

Modes of delivery in preventive intervention studies: a rapid review

scientific article published on July 2014

Multigene panels in prostate cancer risk assessment

scientific article published on July 2012

Multigene panels in prostate cancer risk assessment: a systematic review

scientific article published on October 2015

Muscle fiber diameter assessment in cleft lip using image processing

scientific article published on 4 October 2017

Mutagenic lifestyles? A review of evidence of associations between germ-cell mutations in humans and smoking, alcohol consumption and use of ‘recreational’ drugs ⬇️

scientific article published on October 1, 1994

Newborn bilirubin screening for preventing severe hyperbilirubinemia and bilirubin encephalopathy: a rapid review

scientific article published on 10 January 2017

Nonsyndromic cleft palate: An association study at GWAS candidate loci in a multiethnic sample

scientific article published on 02 March 2018

Occupational risk factors for low grade and high grade glioma: results from an international case control study of adult brain tumours

scientific article

On the synthesis and interpretation of consistent but weak gene-disease associations in the era of genome-wide association studies

scientific article published on 20 December 2006

On track? Using the Human Genome Epidemiology Roadmap

scientific article published on 15 April 2010

Passive smoking in the etiology of non-syndromic orofacial clefts: a systematic review and meta-analysis

scientific article

Patient- and family-oriented outcomes for inborn errors of metabolism: The perspective of patient advocacy and support groups

scientific article published in 2014

Polymorphisms in genes involved in folate metabolism and colorectal neoplasia: a HuGE review

scientific article published on March 2004

Polymorphisms in the methylenetetrahydrofolate reductase (MTHFR) gene, intakes of folate and related B vitamins and colorectal cancer: a case-control study in a population with relatively low folate intake

scientific article published on 6 December 2007

Polymorphisms of adrenergic receptors and the risk of heart failure

scientific article published in January 2003

Postcolposcopy management of women with histologically proven CIN 1: results from TOMBOLA.

scientific article published on July 2014

Postnatal Prediction of Gestational Age Using Newborn Fetal Hemoglobin Levels

scientific article published on December 2016

Postnatal gestational age estimation via newborn screening analysis: application and potential

scientific article published on 17 August 2019

Prevalence at birth of cleft lip with or without cleft palate: data from the International Perinatal Database of Typical Oral Clefts (IPDTOC).

scientific article

Prevention and therapy for BRCA1/2 mutation carriers and women at high risk for breast and ovarian cancer

scientific article

Prevention by daily soluble aspirin of colorectal adenoma recurrence: 4-year results of the APACC randomised trial ⬇️

scientific article published on 02 September 2011

Prevention of orofacial clefts: does pregnancy planning have a role?

scientific article published in May 2007

Primary care role in expanded newborn screening: After the heel prick test

scientific article published on August 2013

Problems and approaches in investigating the role of micronutrients in the aetiology of cancer in humans

scientific article

Prospective head-to-head comparison of accuracy of two sequencing platforms for screening for fetal aneuploidy by cell-free DNA: the PEGASUS study

scientific article published on 23 June 2019

Psychosocial impact of alternative management policies for low-grade cervical abnormalities: results from the TOMBOLA randomised controlled trial

scientific article

Psychosocial morbidity in women with abnormal cervical cytology managed by cytological surveillance or initial colposcopy: longitudinal analysis from the TOMBOLA randomised trial

scientific article

Public Perceptions of the Benefits and Risks of Newborn Screening

scientific article published on 13 July 2015

Public attitudes towards genomic risk profiling as a component of routine population screening

scientific article published on 31 August 2013

Public views on participating in newborn screening using genome sequencing

scientific article

Quality, quantity and harmony: the DataSHaPER approach to integrating data across bioclinical studies

scientific article

Recommendations and proposed guidelines for assessing the cumulative evidence on joint effects of genes and environments on cancer occurrence in humans

scientific article

Reduced risk of colorectal cancer among recent generations in New Zealand ⬇️

scientific article published on August 1, 1992

Refining the management of low-grade cervical abnormalities in the UK National Health Service and defining the potential for human papillomavirus testing: a commentary on emerging evidence

scientific article

Relation of childhood brain tumors to exposure of parents and children to tobacco smoke: the SEARCH international case-control study. Surveillance of Environmental Aspects Related to Cancer in Humans

scientific article published in July 2002

Relationship Between Adiposity and Pulmonary Function in School-Aged Canadian Children

scientific article

Reporting genetic association studies: the STREGA statement

scientific article published in July 2009

Reporting of systematic reviews: the challenge of genetic association studies

scientific article published on June 2007

Reporting, appraising, and integrating data on genotype prevalence and gene-disease associations

scientific article published in August 2002

STrengthening the REporting of Genetic Association Studies (STREGA)-an extension of the STROBE statement

article

STrengthening the REporting of Genetic Association Studies (STREGA): An Extension of the STROBE Statement

article

STrengthening the REporting of Genetic Association Studies (STREGA): an extension of the STROBE statement

scientific article

STrengthening the REporting of Genetic Association studies (STREGA)--an extension of the STROBE statement

scientific article published on April 2009

STrengthening the REporting of Genetic Association studies (STREGA)—an extension of the STROBE statement

article

Scientific reporting is suboptimal for aspects that characterize genetic risk prediction studies: a review of published articles based on the Genetic RIsk Prediction Studies statement

scientific article published on 08 January 2014

Scoping review of patient- and family-oriented outcomes and measures for chronic pediatric disease

scientific article

Screening for depression in women during pregnancy or the first year postpartum and in the general adult population: a protocol for two systematic reviews to update a guideline of the Canadian Task Force on Preventive Health Care

article

Seasonal variation in rates of emergency room visits and acute admissions following recommended infant vaccinations in Ontario, Canada: a self-controlled case series analysis

scientific article published on November 2014

Segregation analysis of cleft lip with or without cleft palate in the First Nations (Amerindian) people of British Columbia and review of isolated cleft palate etiologies

scientific article published on June 2009

Size matters: just how big is BIG?: Quantifying realistic sample size requirements for human genome epidemiology

scientific article (publication date: February 2009)

Strategies for Increasing Cervical Cancer Screening Amongst First Nations Communities in Northwest Ontario, Canada

scientific article published on 6 November 2014

Strengthening the Reporting of Genetic Risk Prediction Studies: The GRIPS Statement

scientific article published on 15 March 2011

Strengthening the reporting of Genetic RIsk Prediction Studies (GRIPS): explanation and elaboration

scientific article published on 16 March 2011

Strengthening the reporting of Genetic RIsk Prediction Studies: the GRIPS Statement

scientific article

Strengthening the reporting of Genetic RIsk Prediction Studies: the GRIPS Statement

scientific article published on 16 March 2011

Strengthening the reporting of Genetic Risk Prediction Studies: The GRIPS statement

scientific article published on 01 May 2011

Strengthening the reporting of genetic association studies (STREGA): an extension of the STROBE Statement

article

Strengthening the reporting of genetic association studies (STREGA): an extension of the STROBE statement

article

Strengthening the reporting of genetic association studies (STREGA): an extension of the strengthening the reporting of observational studies in epidemiology (STROBE) statement

scientific article published on 12 February 2009

Strengthening the reporting of genetic risk prediction studies (GRIPS): explanation and elaboration.

scientific article

Strengthening the reporting of genetic risk prediction studies (GRIPS): explanation and elaboration

scientific article (publication date: April 2011)

Strengthening the reporting of genetic risk prediction studies (GRIPS): explanation and elaboration

Strengthening the reporting of genetic risk prediction studies: The GRIPS Statement

scientific article published in March 2011

Strengthening the reporting of genetic risk prediction studies: the GRIPS statement

scientific article published on 16 March 2011

Strengthening the reporting of genetic risk prediction studies: the GRIPS statement

Strengthening the reporting of genetic risk prediction studies: the GRIPS statement

Strengthening the reporting of genetic risk prediction studies: the GRIPS statement

scientific article published on 15 March 2011

Strengthening the reporting of genetic risk prediction studies: the GRIPS statement.

scientific article

Study protocol: the empirical investigation of methods to correct for measurement error in biobanks with dietary assessment

scientific article

Systematic meta-analyses and field synopsis of genetic and epigenetic studies in paediatric inflammatory bowel disease

scientific article published on 27 September 2016

Systematic meta-analyses and field synopsis of genetic association studies in colorectal adenomas

scientific article published on 07 October 2015

Systematic meta-analyses and field synopsis of genetic association studies in colorectal cancer

scientific article

Systematic meta-analyses, field synopsis and global assessment of the evidence of genetic association studies in colorectal cancer

scientific article published on 09 December 2019

Systematic review of statistical approaches to quantify, or correct for, measurement error in a continuous exposure in nutritional epidemiology

scientific article published on 19 September 2017

Systematic review: family history in risk assessment for common diseases

scientific article published on December 2009

Systematic reviews of genetic association studies. Human Genome Epidemiology Network

scientific article

T-cell receptor excision circle levels and safety of paediatric immunization: A population-based self-controlled case series analysis

scientific article published on 26 February 2018

Teaching tools to engage Anishinaabek First Nations women in cervical cancer screening: Report of an educational workshop

scientific article published on April 2016

The Emergence of Networks in Human Genome Epidemiology

article

The emergence of epidemiology in the genomics age.

scientific article published on 19 August 2004

The emergence of networks in human genome epidemiology: challenges and opportunities

scholarly article published 18 December 2009

The epidemiologic approach to pharmacogenomics

scientific article

The role of cytokine gene polymorphisms in colorectal cancer and their interaction with aspirin use in the northeast of Scotland

scientific article (publication date: July 2005)

The unintended consequences of cervical screening: distress in women undergoing cytologic surveillance

scientific article published in April 2014

The use of relative incidence ratios in self-controlled case series studies: an overview

scientific article

The utility and predictive value of combinations of low penetrance genes for screening and risk prediction of colorectal cancer

scientific article

Tobacco smoking and oral clefts: a meta-analysis.

scientific article published on March 2004

Translating rare-disease therapies into improved care for patients and families: what are the right outcomes, designs, and engagement approaches in health-systems research?

scientific article published on 09 April 2015

Ultrastructural analysis of collagen fibril diameter distribution in cleft lip

scientific article published on 25 September 2018

Understanding sickle cell carrier status identified through newborn screening: a qualitative study.

scientific article

Using Newborn Screening Bloodspots for Research: Public Preferences for Policy Options

scientific article

Using community engagement to inform and implement a community-randomized controlled trial in the anishinaabek cervical cancer screening study

scientific article published on 19 February 2014

Variability in the clinical management of fatty acid oxidation disorders: results of a survey of Canadian metabolic physicians

scientific article

Vitamin D receptor (VDR) polymorphisms and severe RSV bronchiolitis: a systematic review and meta-analysis.

scientific article published on 09 September 2013

Vitamin D status of Canadians as measured in the 2007 to 2009 Canadian Health Measures Survey.

scientific article published on March 2010

Waterpipe smoking and cancer: systematic review and meta-analysis

scientific article published on 10 May 2016

When to replicate systematic reviews of interventions: consensus checklist

scientific article published on 15 September 2020

Who defaults from colposcopy? A multi-centre, population-based, prospective cohort study of predictors of non-attendance for follow-up among women with low-grade abnormal cervical cytology

scientific article published on 24 August 2012

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