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List of works by Scott G Filler

A Fungal Immunotherapeutic Vaccine (NDV-3A) for Treatment of Recurrent Vulvovaginal Candidiasis-A Phase 2 Randomized, Double-Blind, Placebo-Controlled Trial.

scientific article

A forkhead transcription factor is important for true hyphal as well as yeast morphogenesis in Candida albicans

scientific article

A phase II randomized trial of amphotericin B alone or combined with fluconazole in the treatment of HIV-associated cryptococcal meningitis.

scientific article published in June 2009

A possible role for fumagillin in cellular damage during host infection by Aspergillus fumigatus

scientific article published on 01 January 2018

A randomized study of the use of fluconazole in continuous versus episodic therapy in patients with advanced HIV infection and a history of oropharyngeal candidiasis: AIDS Clinical Trials Group Study 323/Mycoses Study Group Study 40.

scientific article published on 12 October 2005

A systematic evaluation of high-dimensional, ensemble-based regression for exploring large model spaces in microbiome analyses

scientific article

APX001A Protects Immunosuppressed Mice from Rhizopus delemar Infection

scientific article

Activation and alliance of regulatory pathways in C. albicans during mammalian infection

scientific article

Als3 is a Candida albicans invasin that binds to cadherins and induces endocytosis by host cells

scientific article

An RNA transport system in Candida albicans regulates hyphal morphology and invasive growth ⬇️

scientific article

An integrated genomic and transcriptomic survey of mucormycosis-causing fungi

scientific article published on 22 July 2016

Anti-CotH3 antibodies protect mice from mucormycosis by prevention of invasion and augmenting opsonophagocytosis.

scientific article published on 12 June 2019

Applying Convergent Immunity to Innovative Vaccines Targeting Staphylococcus aureus.

scientific article

Aspergillus fumigatus AcuM regulates both iron acquisition and gluconeogenesis ⬇️

scientific article published on September 27, 2010

Aspergillus fumigatus CalA binds to integrin α5β1 and mediates host cell invasion ⬇️

scientific article

Aspergillus fumigatus MedA governs adherence, host cell interactions and virulence

scientific article

Aspergillus fumigatus stimulates leukocyte adhesion molecules and cytokine production by endothelial cells in vitro and during invasive pulmonary disease

scientific article published on 19 May 2008

Aspergillus galactosaminogalactan mediates adherence to host constituents and conceals hyphal β-glucan from the immune system.

scientific article

AtrR Is an Essential Determinant of Azole Resistance in Aspergillus fumigatus

scientific article published on 12 March 2019

Author Correction: EphA2 is an epithelial cell pattern recognition receptor for fungal β-glucans

scientific article published on 01 September 2018

Bcr1 functions downstream of Ssd1 to mediate antimicrobial peptide resistance in Candida albicans.

scientific article published on 11 January 2013

Bicarbonate correction of ketoacidosis alters host-pathogen interactions and alleviates mucormycosis

scientific article published on 09 May 2016

CARD9+ microglia promote antifungal immunity via IL-1β- and CXCL1-mediated neutrophil recruitment

scientific article published on 17 April 2019

CX3CR1 is dispensable for control of mucosal Candida albicans infections in mice and humans

scientific article

Calcineurin controls drug tolerance, hyphal growth, and virulence in Candida dubliniensis

scientific article published on 29 April 2011

Calcineurin is essential for Candida albicans survival in serum and virulence

scientific article

Candida albicans Als1p: an adhesin that is a downstream effector of the EFG1 filamentation pathway.

scientific article

Candida albicans Als3, a multifunctional adhesin and invasin

scientific article

Candida albicans CUG mistranslation is a mechanism to create cell surface variation.

scientific article published on 30 August 2013

Candida albicans Cannot Acquire Sufficient Ethanolamine from the Host To Support Virulence in the Absence of De Novo Phosphatidylethanolamine Synthesis.

scientific article published on 23 July 2018

Candida albicans Ecm33p is important for normal cell wall architecture and interactions with host cells

scientific article

Candida albicans Mds3p, a conserved regulator of pH responses and virulence identified through insertional mutagenesis.

scientific article published on December 2002

Candida albicans cell shaving uncovers new proteins involved in cell wall integrity, yeast to hypha transition, stress response and host-pathogen interaction

scientific article

Candida albicans internalization by host cells is mediated by a clathrin-dependent mechanism

scientific article

Candida albicans protein kinase CK2 governs virulence during oropharyngeal candidiasis

scientific article published on 24 August 2006

Candida albicans stimulates local expression of leukocyte adhesion molecules and cytokines in vivo

scientific article published on 11 July 2002

Candida albicans transcription factor Rim101 mediates pathogenic interactions through cell wall functions

scientific article published on 04 July 2008

Candida albicans white-opaque switching influences virulence but not mating during oropharyngeal candidiasis.

scientific article published on 26 March 2018

Candidalysin Is Required for Neutrophil Recruitment and Virulence During Systemic Candida albicans Infection

scientific article published on 01 September 2019

Clinical practice guidelines for the management of candidiasis: 2009 update by the Infectious Diseases Society of America.

scientific article

Combination polyene-caspofungin treatment of rhino-orbital-cerebral mucormycosis

scientific article published on August 2008

Comparative transcriptomics of Aspergillus fumigatus strains upon exposure to human airway epithelial cells

scientific article published on 18 January 2018

Complementary adhesin function in C. albicans biofilm formation

scientific article published on July 2008

Contribution of Candida albicans ALS1 to the pathogenesis of experimental oropharyngeal candidiasis

scientific article published on September 2002

Correction: An RNA Transport System in Candida albicans Regulates Hyphal Morphology and Invasive Growth ⬇️

Correction: The pH-Responsive PacC Transcription Factor of Aspergillus fumigatus Governs Epithelial Entry and Tissue Invasion during Pulmonary Aspergillosis. ⬇️

scientific article published on 18 June 2015

Cost effective, experimentally robust differential-expression analysis for human/mammalian, pathogen and dual-species transcriptomics

scientific article published on 01 January 2020

CotH3 mediates fungal invasion of host cells during mucormycosis

scientific article published on 20 December 2013

Critical role of Bcr1-dependent adhesins in C. albicans biofilm formation in vitro and in vivo.

scientific article published in July 2006

Cryptococcal immune reconstitution inflammatory syndrome after antiretroviral therapy in AIDS patients with cryptococcal meningitis: a prospective multicenter study

scientific article published in September 2009

Cryptococcus gattii VGIII isolates causing infections in HIV/AIDS patients in Southern California: identification of the local environmental source as arboreal

scientific article published in August 2014

Current treatment strategies for disseminated candidiasis

scientific article

Daptomycin versus standard therapy for bacteremia and endocarditis caused by Staphylococcus aureus

scientific article

Deacetylation of Fungal Exopolysaccharide Mediates Adhesion and Biofilm Formation

scientific article published on 5 April 2016

Determining Aspergillus fumigatus transcription factor expression and function during invasion of the mammalian lung

scientific article published on 29 March 2021

Different tumor necrosis factor α antagonists have different effects on host susceptibility to disseminated and oropharyngeal candidiasis in mice

scientific article

Divergent Responses of Different Endothelial Cell Types to Infection with Candida albicans and Staphylococcus aureus ⬇️

scientific article published on June 22, 2012

Divergent targets of Aspergillus fumigatus AcuK and AcuM transcription factors during growth in vitro versus invasive disease

scientific article

Divergent targets of Candida albicans biofilm regulator Bcr1 in vitro and in vivo

scientific article

EGFR and HER2 receptor kinase signaling mediate epithelial cell invasion by Candida albicans during oropharyngeal infection ⬇️

scientific article published on August 13, 2012

Effect of high-dose fluconazole on QT interval in patients with human immunodeficiency virus (HIV)-associated cryptococcal meningitis

scientific article published on 30 June 2009

Efficacy of ambruticin analogs in a murine model of invasive pulmonary aspergillosis

scientific article

Efficacy of liposomal amphotericin B and posaconazole in intratracheal models of murine mucormycosis

scientific article published on 06 May 2013

Efficacy of the anti-Candida rAls3p-N or rAls1p-N vaccines against disseminated and mucosal candidiasis

scientific article

Elucidating the Candida albicans calcineurin signaling cascade controlling stress response and virulence

scientific article published on 13 September 2009

Endocytosis of Candida albicans by vascular endothelial cells is associated with tyrosine phosphorylation of specific host cell proteins

scientific article

Endothelial cell stimulation by Candida albicans

scientific article published on January 2009

EphA2 Is a Neutrophil Receptor for Candida albicans that Stimulates Antifungal Activity during Oropharyngeal Infection

scientific article published on 01 July 2019

EphA2 is an epithelial cell pattern recognition receptor for fungal β-glucans

scientific article published on 13 November 2017

Exposure to the oral host niche yields rapid phenotypic and genotypic diversification inCandida albicans

Flotillin-Dependent Membrane Microdomains Are Required for Functional Phagolysosomes against Fungal Infections

scientific article published on 01 August 2020

Fosmanogepix (APX001) is Effective in the Treatment of Pulmonary Murine Mucormycosis Due to Rhizopus arrhizus

scientific article published on 23 March 2020

Functional Coupling between the Unfolded Protein Response and Endoplasmic Reticulum/Golgi Ca2+-ATPases Promotes Stress Tolerance, Cell Wall Biosynthesis, and Virulence of Aspergillus fumigatus

scientific article published on 02 June 2020

Functional analysis of the Candida albicans ALS1 gene product

scientific article

Functional and structural diversity in the Als protein family of Candida albicans

scientific article

Functional convergence of gliP and aspf1 in Aspergillus fumigatus pathogenicity

scholarly article published by Scott G Filler in 2018

Fungal invasion of normally non-phagocytic host cells

scientific article

GRP78 and Integrins Play Different Roles in Host Cell Invasion during Mucormycosis

scientific article published on 02 June 2020

Gene Expression Profiling of Infecting Microbes Using a Digital Bar-coding Platform.

scientific article published on 13 January 2016

Genetic basis for differential activities of fluconazole and voriconazole against Candida krusei

scientific article

Genetic variation of DNA methyltransferase-3A contributes to protection against persistent MRSA bacteremia in patients

scientific article published on 16 September 2019

Genome Sequence for Candida albicans Clinical Oral Isolate 529L

scientific article published on 20 June 2019

Gliotoxin production in Aspergillus fumigatus contributes to host-specific differences in virulence

scientific article

Glycerophosphocholine utilization by Candida albicans: role of the Git3 transporter in virulence

scientific article published on 10 October 2013

Guidelines for treatment of candidiasis

scientific article published on 19 December 2003

Host cell invasion and virulence mediated by Candida albicans Ssa1. ⬇️

scientific article

Human Als3p Antibodies are Surrogate Markers of NDV-3A Vaccine Efficacy Against Recurrent Vulvovaginal Candidiasis

Human Anti-Als3p Antibodies Are Surrogate Markers of NDV-3A Vaccine Efficacy Against Recurrent Vulvovaginal Candidiasis.

scientific article

IL-17 Receptor Signaling in Oral Epithelial Cells Is Critical for Protection against Oropharyngeal Candidiasis.

scientific article

Identification of <i>Candida glabrata</i> Transcriptional Regulators that Govern Stress Resistance and Virulence

scientific article published on 14 December 2020

In vitro endothelial cell damage is positively correlated with enhanced virulence and poor vancomycin responsiveness in experimental endocarditis due to methicillin-resistant Staphylococcus aureus ⬇️

scientific article published on July 21, 2011

In vivo analysis of Aspergillus fumigatus developmental gene expression determined by real-time reverse transcription-PCR

scientific article published on 19 May 2008

In vivo and ex vivo comparative transcriptional profiling of invasive and non-invasive Candida albicans isolates identifies genes associated with tissue invasion

scientific article published in March 2007

Inhibiting mitochondrial phosphate transport as an unexploited antifungal strategy

scientific article published on 11 December 2017

Inhibition of EGFR Signaling Protects from Mucormycosis

scientific article published on 14 August 2018

Innate Immune Memory Contributes to Host Defense against Recurrent Skin and Skin Structure Infections Caused by Methicillin-Resistant Staphylococcus aureus

scientific article

Interactions of Candida albicans with epithelial cells

scientific article

Intersection of phosphate transport, oxidative stress and TOR signalling in Candida albicans virulence

scientific article published on 30 July 2018

Invasive pulmonary mucormycosis and aspergillosis in a patient with decompensated hepatic cirrhosis

scientific article published on 6 March 2018

Investigation of the Function of Candida albicans Als3 by Heterologous Expression in Candida glabrata ⬇️

scientific article published on April 29, 2013

Mechanisms of Candida albicans Trafficking to the Brain ⬇️

scientific article published on October 6, 2011

Mechanisms of NDV-3 vaccine efficacy in MRSA skin versus invasive infection.

scientific article

Methodologies for in vitro and in vivo evaluation of efficacy of antifungal and antibiofilm agents and surface coatings against fungal biofilms.

scientific article published on 14 June 2018

Mice with disseminated candidiasis die of progressive sepsis

scientific article published on 03 June 2005

Microbial glycoside hydrolases as antibiofilm agents with cross-kingdom activity.

scientific article published on 20 June 2017

N-cadherin mediates endocytosis of Candida albicans by endothelial cells

scientific article published on 4 January 2005

NDV-3 protects mice from vulvovaginal candidiasis through T- and B-cell immune response

scientific article published on 21 September 2013

NDV-3, a recombinant alum-adjuvanted vaccine for Candida and Staphylococcus aureus, is safe and immunogenic in healthy adults.

scientific article

New signaling pathways govern the host response to C. albicans infection in various niches

scientific article published on 9 April 2015

Next-generation computational genetic analysis: multiple complement alleles control survival after Candida albicans infection.

scientific article

Nonredundant Roles of Interleukin-17A (IL-17A) and IL-22 in Murine Host Defense against Cutaneous and Hematogenous Infection Due to Methicillin-Resistant Staphylococcus aureus.

scientific article

Novel Host Pathways Govern Epithelial Cell Invasion of Aspergillus fumigatus

scientific article published in 2023

Novel inhalational murine model of invasive pulmonary aspergillosis

scientific article published on May 2004

Oropharyngeal Candidiasis: Fungal Invasion and Epithelial Cell Responses.

scientific article

Overlapping and distinct roles of Aspergillus fumigatus UDP-glucose 4-epimerases in galactose metabolism and the synthesis of galactose-containing cell wall polysaccharides.

scientific article

Parenchymal Organ, and Not Splenic, Immunity Correlates with Host Survival during Disseminated Candidiasis ⬇️

scientific article published on October 1, 2003

Pathogen Gene Expression Profiling During Infection Using a Nanostring nCounter Platform

scientific article published on January 2016

Pharmacokinetics of Posaconazole Within Epithelial Cells and Fungi: Insights Into Potential Mechanisms of Action During Treatment and Prophylaxis ⬇️

scientific article published on November 15, 2013

Phase I evaluation of the safety and pharmacokinetics of murine-derived anticryptococcal antibody 18B7 in subjects with treated cryptococcal meningitis

scientific article

Phase II, randomized, double-blind, multicenter study comparing the safety and pharmacokinetics of tefibazumab to placebo for treatment of Staphylococcus aureus bacteremia

scientific article

Plasma Membrane Phosphatidylinositol-4-Phosphate Is Not Necessary for Candida albicans Viability yet Is Key for Cell Wall Integrity and Systemic Infection

scientific article published on 15 February 2022

Polarized response of endothelial cells to invasion by Aspergillus fumigatus ⬇️

scientific article

Prophylactic Treatment with VT-1161 Protects Immunosuppressed Mice from Rhizopus arrhizus var. arrhizus Infection.

scientific article published on 26 June 2017

Protective immunity in recurrent infection reflects localized immune signatures and macrophage-conferred memory

article published in the Proceedings of the National Academy of Sciences of the United States of America

Proteome Analysis Reveals the Conidial Surface Protein CcpA Essential for Virulence of the Pathogenic Fungus

article

Proteomic profiling of the monothiol glutaredoxin Grx3 reveals its global role in the regulation of iron dependent processes

scientific article published on 11 June 2020

Publisher Correction: EphA2 is an epithelial cell pattern recognition receptor for fungal β-glucans.

scientific article published on 13 February 2018

Rapid Phenotypic and Genotypic Diversification After Exposure to the Oral Host Niche in Candida albicans

scientific article published on 03 May 2018

Regulatory role of glycerol in Candida albicans biofilm formation.

scientific article published on 9 April 2013

Relationship between Candida albicans virulence during experimental hematogenously disseminated infection and endothelial cell damage in vitro.

scientific article

Requirement for Candida albicans Sun41 in biofilm formation and virulence.

scientific article

Role of Arf GTPases in fungal morphogenesis and virulence

scientific article

Role of Aspergillus fumigatus DvrA in Host Cell Interactions and Virulence ⬇️

scientific article published on July 30, 2010

Role of endothelial cell septin 7 in the endocytosis of Candida albicans

scientific article

Role of retrograde trafficking in stress response, host cell interactions, and virulence of Candida albicans

scientific article published on 20 December 2013

Role of the fungal Ras-protein kinase A pathway in governing epithelial cell interactions during oropharyngeal candidiasis

scientific article

Role of trehalose biosynthesis in Aspergillus fumigatus development, stress response, and virulence

scientific article

Roles of Candida albicans Mig1 and Mig2 in glucose repression, pathogenicity traits, and SNF1 essentiality

scientific article published on 21 January 2020

SR-Like RNA-Binding Protein Slr1 Affects Candida albicans Filamentation and Virulence ⬇️

scientific article published on February 4, 2013

SSD1 is integral to host defense peptide resistance in Candida albicans

scientific article

Selection of Candida albicans trisomy during oropharyngeal infection results in a commensal-like phenotype.

scientific article

Serum bridging molecules drive candidal invasion of human but not mouse endothelial cells

scientific article published on 07 July 2022

Standardization of an experimental murine model of invasive pulmonary aspergillosis

scientific article

Synergistic regulation of hyphal elongation by hypoxia, CO(2), and nutrient conditions controls the virulence of Candida albicans

scientific article

Systemic Staphylococcus aureus infection mediated by Candida albicans hyphal invasion of mucosal tissue ⬇️

scientific article

Targeted enrichment outperforms other enrichment techniques and enables more multi-species RNA-Seq analyses

scientific article published in Scientific Reports

Th17 cells and IL-17 receptor signaling are essential for mucosal host defense against oral candidiasis

scientific article published on 09 February 2009

The Aryl Hydrocarbon Receptor Governs Epithelial Cell Invasion during Oropharyngeal Candidiasis

scientific article

The Aspergillus fumigatus StuA protein governs the up-regulation of a discrete transcriptional program during the acquisition of developmental competence

scientific article

The Aspergillus fumigatus transcription factor Ace2 governs pigment production, conidiation and virulence.

scientific article published on 11 February 2009

The Case for Adopting the "Species Complex" Nomenclature for the Etiologic Agents of Cryptococcosis

scientific article (publication date: 11 January 2017)

The Fungal Exopolysaccharide Galactosaminogalactan Mediates Virulence by Enhancing Resistance to Neutrophil Extracellular Traps

scientific article published on 22 October 2015

The Hyr1 protein from the fungus Candida albicans is a cross kingdom immunotherapeutic target for Acinetobacter bacterial infection.

scientific article

The Yak1 kinase is involved in the initiation and maintenance of hyphal growth in Candida albicans

scientific article published on 5 March 2008

The anti-Candida albicans vaccine composed of the recombinant N terminus of Als1p reduces fungal burden and improves survival in both immunocompetent and immunocompromised mice

scientific article published in September 2005

The antifungal vaccine derived from the recombinant N terminus of Als3p protects mice against the bacterium Staphylococcus aureus

scientific article published on 21 July 2008

The endothelial cell receptor GRP78 is required for mucormycosis pathogenesis in diabetic mice.

scientific article

The pH-responsive PacC transcription factor of Aspergillus fumigatus governs epithelial entry and tissue invasion during pulmonary aspergillosis ⬇️

scientific article (publication date: October 2014)

Transcriptional responses of candida albicans to epithelial and endothelial cells.

scientific article published on 21 August 2009

Transcriptome profile of the vascular endothelial cell response to Candida albicans

scientific article

Tumor necrosis factor inhibition and invasive fungal infections

scientific article published on August 2005

Using Bayesian modelling to investigate factors governing antibiotic-induced Candida albicans colonization of the GI tract

scientific article

VT-1161 Protects Immunosuppressed Mice from Rhizopus arrhizus var. arrhizus Infection

scientific article published on 14 September 2015

Vaccination with recombinant N-terminal domain of Als1p improves survival during murine disseminated candidiasis by enhancing cell-mediated, not humoral, immunity

scientific article

Yeast casein kinase 2 governs morphology, biofilm formation, cell wall integrity, and host cell damage of Candida albicans.

scientific article

endocarditis diagnosed by fungemia plus serum antigen testing

scholarly article by Timothy J Hatlen et al published March 2019 in Medical mycology case reports

the hyphal-associated adhesin and invasin Als3 of Candida albicans mediates iron acquisition from host ferritin

scientific article

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