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List of works by Mihai Gheorghiade

"Targeting the Heart" in Heart Failure: Myocardial Recovery in Heart Failure With Reduced Ejection Fraction

scientific article published on September 2015

A Critical Appraisal of Short-term Endpoints in Acute Heart Failure Clinical Trials

scientific article published on 11 September 2018

A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes ⬇️

scientific article published on April 27, 2011

A Review of Phase II Acute Heart Failure Syndromes Clinical Trials ⬇️

scientific article published on October 1, 2011

A comprehensive, longitudinal description of the in-hospital and post-discharge clinical, laboratory, and neurohormonal course of patients with heart failure who die or are re-hospitalized within 90 days: analysis from the EVEREST trial

article

A new educational program in heart failure drug development: the Brescia international master program

scientific article published on 01 August 2018

A phase 1-2 dose-escalating study evaluating the safety and tolerability of istaroxime and specific effects on electrocardiographic and hemodynamic parameters in patients with chronic heart failure with reduced systolic function

scientific article published on 20 September 2006

A propensity matched study of the association of education and outcomes in chronic heart failure

scientific article published on 23 July 2007

A propensity-matched study of the association of low serum potassium levels and mortality in chronic heart failure

scientific article published on June 2007

A randomized controlled study of finerenone vs. eplerenone in patients with worsening chronic heart failure and diabetes mellitus and/or chronic kidney disease

scientific article published on 29 April 2016

A randomized, double-blind comparison of 10 and 20 mg lercanidipine in patients with stable effort angina: effects on myocardial ischemia and heart rate variability

scientific article published in September 2002

A randomized, double-blind comparison of lercanidipine 10 and 20 mg in patients with stable effort angina: clinical evaluation of cardiac function by ambulatory ventricular scintigraphic monitoring

scientific article published in November 2004

Ace inhibitor therapy for heart failure in patients with impaired renal function: a review of the literature ⬇️

scientific article published on March 1, 2013

Acute Cardiac Care: Apocalypse Now!

journal article; published in Acute Cardiac Care in 2006

Acute Dyspnea and Decompensated Heart Failure

scientific article published in February 2018

Acute Heart Failure Syndromes: The Role of Vasopressin Antagonists

journal article; published in Acute Cardiac Care in 2009

Acute Heart Failure Treatment

Acute heart failure clinical drug development: from planning to proof of activity to phase III.

scientific article published on 28 September 2010

Acute heart failure syndromes

scientific article published on February 2009

Acute heart failure syndromes and coronary perfusion

scientific article published on July 2008

Acute heart failure syndromes in patients with coronary artery disease early assessment and treatment

scientific article published on January 2009

Acute heart failure syndromes.

scientific article published on 11 August 2009

Acute heart failure syndromes: clinical scenarios and pathophysiologic targets for therapy

scientific article published on June 2007

Acute heart failure syndromes: current state and framework for future research

scientific article

Acute heart failure syndromes: epidemiology, risk stratification and prognostic factors

scientific article published on January 2009

Acute heart failure syndromes: highlights from the ESC Working Group on Acute Cardiac Care Meeting Prague, Czech Republic 2006.

scientific article published in January 2006

Acute heart failure syndromes: potential strategies to improve post-discharge outcomes

scientific article

Acute heart failure treatment: traditional and new drugs

scientific article published on 20 April 2010

Acute heart failure with low cardiac output: can we develop a short-term inotropic agent that does not increase adverse events?

scientific article published on September 2010

Acute heart failure: multiple clinical profiles and mechanisms require tailored therapy

scientific article published on 26 May 2010

Acute hemodynamic effects of tolvaptan, a vasopressin V2 receptor blocker, in patients with symptomatic heart failure and systolic dysfunction: an international, multicenter, randomized, placebo-controlled trial

scientific article

Adherence to Aldosterone-Blocking Agents in Patients with Heart Failure ⬇️

scientific article published on September 1, 2010

Adherence to guideline-recommended adjunctive heart failure therapies among outpatient cardiology practices (findings from IMPROVE HF).

scientific article published in January 2010

Admission or changes in renal function during hospitalization for worsening heart failure predict postdischarge survival: results from the Outcomes of a Prospective Trial of Intravenous Milrinone for Exacerbations of Chronic Heart Failure (OPTIME-CH

scientific article published on May 2008

Age- and gender-related differences in quality of care and outcomes of patients hospitalized with heart failure (from OPTIMIZE-HF).

scientific article published in July 2009

Agents with inotropic properties for the management of acute heart failure syndromes. Traditional agents and beyond

scientific article

Agents with vasodilator properties in acute heart failure: how to design successful trials

scientific article

Aldosterone antagonists and outcomes in real-world older patients with heart failure and preserved ejection fraction

scientific article published on February 2013

Aldosterone blockade in post-acute myocardial infarction heart failure.

scientific article published on October 2006

Aldosterone receptor blockade in patients with left ventricular systolic dysfunction following acute myocardial infarction

scientific article published on February 2008

Amino acids and derivatives, a new treatment of chronic heart failure?

scientific article

Angiotensin receptor blockers and outcomes in real-world older patients with heart failure and preserved ejection fraction: a propensity-matched inception cohort clinical effectiveness study

scientific article

Angiotensin-converting enzyme inhibitors and outcomes in heart failure and preserved ejection fraction

scientific article published on 16 March 2013

Anticoagulation in heart failure: current status and future direction

scientific article

Are BNP changes during hospitalization for heart failure a reliable surrogate for predicting the effects of therapies on post-discharge mortality?

scientific article published in June 2009

Are the American College of Cardiology/Emergency Cardiac Care (ACC/ECC) guidelines useful in triaging patients to telemetry units?

journal article; published in Acute Cardiac Care in 2006

Assessing and grading congestion in acute heart failure: a scientific statement from the acute heart failure committee of the heart failure association of the European Society of Cardiology and endorsed by the European Society of Intensive Care Medi

scientific article published on 30 March 2010

Assessment and key targets for therapy in the post-myocardial infarction patient with left ventricular dysfunction

scientific article published on September 2008

Assessment of dyspnea early in acute heart failure: patient characteristics and response differences between likert and visual analog scales.

scientific article

Association between diabetes mellitus and post-discharge outcomes in patients hospitalized with heart failure: findings from the EVEREST trial

scientific article

Association between funding sources and the scope and outcomes of cardiovascular clinical trials: A systematic review

scientific article published on 22 December 2016

Association between performance measures and clinical outcomes for patients hospitalized with heart failure

scientific article published in January 2007

Association of arginine vasopressin levels with outcomes and the effect of V2 blockade in patients hospitalized for heart failure with reduced ejection fraction: insights from the EVEREST trial

scientific article published on 12 December 2012

Association of low body temperature and poor outcomes in patients admitted with worsening heart failure: a substudy of the Efficacy of Vasopressin Antagonism in Heart Failure Outcome Study with Tolvaptan (EVEREST) trial

scientific article published on 15 July 2013

Associations between outpatient heart failure process-of-care measures and mortality

scientific article published on 04 April 2011

Atrial fibrillation or flutter on initial electrocardiogram is associated with worse outcomes in patients admitted for worsening heart failure with reduced ejection fraction: Findings from the EVEREST Trial

article

Autologous non-myeloablative haemopoietic stem-cell transplantation compared with pulse cyclophosphamide once per month for systemic sclerosis (ASSIST): an open-label, randomised phase 2 trial

scientific article published on 21 July 2011

B-type natriuretic peptide assessment in ambulatory heart failure patients: insights from IMPROVE HF.

scientific article

B-type natriuretic peptide: from bench to bedside

scientific article

Bayesian adaptive trial design in acute heart failure syndromes: moving beyond the mega trial

scientific article

Benefit of exercise therapy for systolic heart failure in relation to disease severity and etiology—findings from the Heart Failure and A Controlled Trial Investigating Outcomes of Exercise Training study ⬇️

scientific article published on December 1, 2011

Beta blocker therapy after acute myocardial infarction in patients with heart failure and systolic dysfunction

scientific article

Beta-blockers in older patients with heart failure and preserved ejection fraction: class, dosage, and outcomes

scientific article

Beta-blockers in the post-myocardial infarction patient

scientific article published in July 2002

Beyond pulmonary edema: diagnostic, risk stratification, and treatment challenges of acute heart failure management in the emergency department

scientific article published on 14 September 2007

Cachexia: common, deadly, with an urgent need for precise definition and new therapies

scientific article

Cancer Therapy-Related Cardiac Dysfunction and Heart Failure: Part 1: Definitions, Pathophysiology, Risk Factors, and Imaging

scientific article

Cancer Therapy-Related Cardiac Dysfunction and Heart Failure: Part 2: Prevention, Treatment, Guidelines, and Future Directions

scientific article published on February 2016

Cardiac involvement and treatment-related mortality after non-myeloablative haemopoietic stem-cell transplantation with unselected autologous peripheral blood for patients with systemic sclerosis: a retrospective analysis

scientific article published on 28 January 2013

Cardiac resynchronization therapy utilization for heart failure: findings from IMPROVE HF.

scientific article published on December 2009

Cardiovascular clinical trials with noninferiority or equivalence designs from 2001 to 2012.

scientific article published on 26 March 2016

Cardiovascular risk assessment of the liver transplant candidate

scientific article published on July 2011

Carvedilol use at discharge in patients hospitalized for heart failure is associated with improved survival: An analysis from Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients with Heart Failure (OPTIMIZE-HF)

article

Carvedilol: beta-blockade and beyond.

scientific article published on January 2004

Causes of death and rehospitalization in patients hospitalized with worsening heart failure and reduced left ventricular ejection fraction: results from Efficacy of Vasopressin Antagonism in Heart Failure Outcome Study with Tolvaptan (EVEREST) progr

scientific article published in May 2010

Changes in Dyspnea Status During Hospitalization and Postdischarge Health-Related Quality of Life in Patients Hospitalized for Heart Failure: Findings From the EVEREST Trial

scientific article published on May 2016

Changes in Serum Potassium Levels During Hospitalization in Patients With Worsening Heart Failure and Reduced Ejection Fraction (from the EVEREST Trial)

Characteristics, treatments, and outcomes of patients with preserved systolic function hospitalized for heart failure: a report from the OPTIMIZE-HF Registry

scientific article published on 6 August 2007

Characterization and Prognostic Value of Persistent Hyponatremia in Patients With Severe Heart Failure in the ESCAPE Trial

article

Cinaciguat, a soluble guanylate cyclase activator: results from the randomized, controlled, phase IIb COMPOSE programme in acute heart failure syndromes ⬇️

article by Mihai Gheorghiade et al published September 2012 in European Journal of Heart Failure

Clinical characteristics and outcomes of hospitalized heart failure patients with systolic dysfunction and chronic obstructive pulmonary disease: findings from OPTIMIZE-HF.

scientific article published on 2 February 2012

Clinical course and predictive value of congestion during hospitalization in patients admitted for worsening signs and symptoms of heart failure with reduced ejection fraction: findings from the EVEREST trial

scientific article published on 4 January 2013

Clinical course and predictive value of liver function tests in patients hospitalized for worsening heart failure with reduced ejection fraction: an analysis of the EVEREST trial

article

Clinical course of patients with hyponatremia and decompensated systolic heart failure and the effect of vasopressin receptor antagonism with tolvaptan

scientific article published on 14 May 2013

Clinical development of pharmacologic agents for acute heart failure syndromes: a proposal for a mechanistic translational phase

scientific article published on 28 December 2010

Clinical effectiveness of CRT and ICD therapy in heart failure patients by racial/ethnic classification: insights from the IMPROVE HF registry

scientific article

Clinical effectiveness of cardiac resynchronization and implantable cardioverter-defibrillator therapy in men and women with heart failure: findings from IMPROVE HF.

scientific article published on 31 October 2013

Clinical implications of QRS duration in patients hospitalized with worsening heart failure and reduced left ventricular ejection fraction

scientific article published in June 2008

Clinical outcome endpoints in heart failure trials: a European Society of Cardiology Heart Failure Association consensus document

scientific article published on 19 June 2013

Clinical outcomes in patients on beta-blocker therapy admitted with worsening chronic heart failure

scientific article

Clinical profile and prognostic significance of natriuretic peptide trajectory following hospitalization for worsening chronic heart failure: findings from the ASTRONAUT trial

scientific article published on January 2015

Clinical profile and prognostic value of anemia at the time of admission and discharge among patients hospitalized for heart failure with reduced ejection fraction: findings from the EVEREST trial

scientific article

Clinical profile and prognostic value of low systolic blood pressure in patients hospitalized for heart failure with reduced ejection fraction: Insights from the Efficacy of Vasopressin Antagonism in Heart Failure: Outcome Study with Tolvaptan (EVERE

article

Clinical profiles in acute heart failure: one size fits all or not at all?

scientific article published on 8 August 2017

Clinical trials in acute heart failure: beginning of the end or end of the beginning?

scientific article published on 28 June 2017

Clinical trials in acute heart failure: simpler solutions to complex problems. Consensus document arising from a European Society of Cardiology cardiovascular round-table think tank on acute heart failure, 12 May 2009.

scientific article published on 29 September 2011

Clinical trials in hospitalized heart failure patients: targeting interventions to optimal phenotypic subpopulations

scientific article published on July 2015

Clinical trials of pharmacological therapies in acute heart failure syndromes: lessons learned and directions forward

scientific article published on March 2010

Combination decongestion therapy in hospitalized heart failure: loop diuretics, mineralocorticoid receptor antagonists and vasopressin antagonists

scientific article published on July 2015

Combining Diuretic Response and Hemoconcentration to Predict Rehospitalization After Admission for Acute Heart Failure

scientific article published on June 2016

Combining SERCA2a activation and Na-K ATPase inhibition: a promising new approach to managing acute heart failure syndromes with low cardiac output.

scientific article published on August 2011

Comparison of medical therapy dosing in outpatients cared for in cardiology practices with heart failure and reduced ejection fraction with and without device therapy: report from IMPROVE HF.

scientific article

Concomitant diabetes mellitus and heart failure

scientific article

Congestion as a therapeutic target in acute heart failure syndromes

scientific article published on March 2010

Congestion in acute heart failure syndromes: an essential target of evaluation and treatment

scientific article published on December 2006

Congestion in acute heart failure syndromes: importance of early recognition and treatment.

scientific article published on January 2006

Congestion is an important diagnostic and therapeutic target in heart failure

scientific article published on January 2006

Contemporary Drug Development in Heart Failure: Call for Hemodynamically Neutral Therapies

scientific article

Contemporary cardiovascular device clinical trials (trends and patterns 2001 to 2012).

scientific article published on 18 April 2015

Contemporary use of digoxin in the management of cardiovascular disorders

scientific article

Continental differences in clinical characteristics, management, and outcomes in patients hospitalized with worsening heart failure results from the EVEREST (Efficacy of Vasopressin Antagonism in Heart Failure: Outcome Study with Tolvaptan) program

scientific article

Contrasting acute and chronic effects of tolvaptan on serum osmolality in the EVEREST trial.

scientific article published on 7 October 2015

Coronary artery disease and prevention of heart failure

scientific article published in September 2004

Coronary artery disease in patients with heart failure: incidental, coincidental, or a target for therapy?

scientific article published on 19 February 2014

Coronary artery disease, coronary revascularization, and outcomes in chronic advanced systolic heart failure

scientific article

Coronary multidetector computed tomographic angiography to evaluate coronary artery disease in liver transplant candidates: methods, feasibility and initial experience ⬇️

scientific article published on July 1, 2011

Critical elements of clinical follow-up after hospital discharge for heart failure: insights from the EVEREST trial

scientific article published on March 2010

Critical reappraisal of pulmonary artery catheterization and invasive hemodynamic assessment in acute heart failure

scientific article published on April 2013

Current management and future directions for the treatment of patients hospitalized for heart failure with low blood pressure

scientific article published on March 2013

Current medical treatment for the exacerbation of chronic heart failure resulting in hospitalization

scientific article

Current perspectives the cardiorenal syndrome: recognition and treatment

scientific article

Day of admission and clinical outcomes for patients hospitalized for heart failure: findings from the Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients With Heart Failure (OPTIMIZE-HF).

scientific article

Decongestion in acute heart failure

scientific article

Demographics, clinical characteristics, and outcomes of patients hospitalized for decompensated heart failure: observations from the IMPACT-HF registry

scientific article published in April 2005

Depression and Clinical Outcomes in Heart Failure: An OPTIMIZE-HF Analysis

article

Designing effective drug and device development programs for hospitalized heart failure: a proposal for pretrial registries

scientific article

Developing New Treatments for Heart Failure: Focus on the Heart

scientific article

Developing therapies for heart failure with preserved ejection fraction: current state and future directions

scientific article

Dietary sodium intake in heart failure

scientific article published on July 2012

Digitoxin prolongs survival of female rats with heart failure due to large myocardial infarction

scientific article published on 25 June 2009

Digoxin

scientific article

Digoxin and reduction in mortality and hospitalization in heart failure: a comprehensive post hoc analysis of the DIG trial

scientific article

Digoxin for the treatment of chronic and acute heart failure syndromes

scientific article published on January 2009

Digoxin in the management of cardiovascular disorders

scientific article

Digoxin reduces 30-day all-cause hospital admission in older patients with chronic systolic heart failure

scientific article published on 12 March 2013

Digoxin--new perspective on an old drug.

scientific article published in October 2002

Directions for research in the post-myocardial infarction patient with left ventricular dysfunction

scientific article published on September 2008

Dissociation between hemodynamic changes and symptom improvement in patients with advanced congestive heart failure

scientific article published in June 2002

Diuretic therapy in heart failure: current controversies and new approaches for fluid removal

scientific article published on August 2010

Does aspirin use adversely influence intermediate-term postdischarge outcomes for hospitalized patients who are treated with angiotensin-converting enzyme inhibitors or angiotensin receptor blockers? Findings from Organized Program to Facilitate Lif

scientific article published in February 2010

Dose of Angiotensin-Converting Enzyme Inhibitors and Angiotensin Receptor Blockers and Outcomes in Heart Failure: A Meta-Analysis

scientific article published on August 2017

Dosing of beta-blocker therapy before, during, and after hospitalization for heart failure (from Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients with Heart Failure).

scientific article published on 6 September 2008

Drug Development for Heart Failure With Preserved Ejection Fraction: What Pieces Are Missing From the Puzzle?

scientific article

Drug therapy to reduce early readmission risk in heart failure: ready for prime time?

scientific article

Dual Vasopressin V1a/V2 Antagonism: the Next Step in Neurohormonal Modulation in Patients with Heart Failure?

scientific article published on 9 January 2018

EVEREST study: Efficacy of Vasopressin Antagonism in Heart Failure Outcome Study with Tolvaptan

scientific article published in November 2008

Early pharmacological treatment of acute heart failure syndromes: a systematic review of clinical trials

scientific article published on January 2007

Echocardiographic Evaluation of Left Ventricular Structure and Function: New Modalities and Potential Applications in Clinical Trials ⬇️

scientific article published on December 22, 2011

Effect of Vericiguat, a Soluble Guanylate Cyclase Stimulator, on Natriuretic Peptide Levels in Patients With Worsening Chronic Heart Failure and Reduced Ejection Fraction: The SOCRATES-REDUCED Randomized Trial

scientific article

Effect of aliskiren on post-discharge outcomes among diabetic and non-diabetic patients hospitalized for heart failure: insights from the ASTRONAUT trial

scientific article published on 02 September 2013

Effect of aliskiren on postdischarge mortality and heart failure readmissions among patients hospitalized for heart failure: the ASTRONAUT randomized trial

scientific article published on March 2013

Effect of oral digoxin in high-risk heart failure patients: a pre-specified subgroup analysis of the DIG trial

scientific article

Effects of amino acid supplementation on left ventricular remodeling in patients with chronic heart failure with decreased systolic function and diabetes mellitus: rationale and design of a magnetic resonance imaging study

scientific article published in April 2004

Effects of digoxin on morbidity and mortality in diastolic heart failure: the ancillary digitalis investigation group trial

scientific article published on 24 July 2006

Effects of istaroxime on diastolic stiffness in acute heart failure syndromes: results from the Hemodynamic, Echocardiographic, and Neurohormonal Effects of Istaroxime, a Novel Intravenous Inotropic and Lusitropic Agent: a Randomized Controlled Tria

scientific article

Effects of levosimendan versus dobutamine on inflammatory and apoptotic pathways in acutely decompensated chronic heart failure

scientific article published on 6 May 2006

Effects of oral amino Acid supplements on functional capacity in patients with chronic heart failure

scientific article published on 21 May 2014

Effects of oral tolvaptan in patients hospitalized for worsening heart failure: the EVEREST Outcome Trial

scientific article

Effects of tolvaptan on dyspnoea relief from the EVEREST trials

scientific article published on 27 June 2009

Effects of tolvaptan on physician-assessed symptoms and signs in patients hospitalized with acute heart failure syndromes: analysis from the efficacy of vasopressin antagonism in heart failure outcome study with tolvaptan (EVEREST) trials

scientific article

Effects of tolvaptan, a vasopressin antagonist, in patients hospitalized with worsening heart failure: a randomized controlled trial

scientific article

Efficacy of oral tolvaptan in acute heart failure patients with hypotension and renal impairment

article

Electronic health records and quality of care for heart failure

scientific article published in April 2010

Employing Extracellular Volume Cardiovascular Magnetic Resonance Measures of Myocardial Fibrosis to Foster Novel Therapeutics

scientific article published on June 2017

Endothelial dysfunction, arterial stiffness, and heart failure

scientific article published on 19 September 2012

Endpoints for diuresis: are we there yet?

scientific article published on 4 December 2013

Enhancing the metabolic substrate: PPAR-alpha agonists in heart failure ⬇️

scientific article published on January 1, 2012

Epidemiology and outcome of the cardio-renal syndrome

scientific article

Epidemiology, pathophysiology, and in-hospital management of pulmonary edema: data from the Romanian Acute Heart Failure Syndromes registry

scientific article

Eplerenone reduces mortality 30 days after randomization following acute myocardial infarction in patients with left ventricular systolic dysfunction and heart failure

scientific article published in August 2005

Equitable improvement for women and men in the use of guideline-recommended therapies for heart failure: findings from IMPROVE HF.

scientific article published on December 2010

Evaluation of eplerenone in the subgroup of EPHESUS patients with baseline left ventricular ejection fraction <or=30%.

scientific article published on 28 February 2006

Evaluative framework for phase II studies in patients with heart failure and preserved ejection fraction.

scientific article published in April 2013

Evidence of clinical practice heterogeneity in the use of implantable cardioverter-defibrillators in heart failure and post–myocardial infarction left ventricular dysfunction: Findings from IMPROVE HF

article

Evidence-based use of levosimendan in different clinical settings

scientific article

Expanding the scope of the "polypill" to heart failure

scientific article published on August 2013

Expert consensus document: Mitochondrial function as a therapeutic target in heart failure

scientific article published on 22 December 2016

Exploring New Endpoints for Patients With Heart Failure With Preserved Ejection Fraction

scientific article

Factors associated with improvement in ejection fraction in clinical practice among patients with heart failure: findings from IMPROVE HF.

scientific article published on January 2012

Factors identified as precipitating hospital admissions for heart failure and clinical outcomes: findings from OPTIMIZE-HF.

scientific article

Finding the road to recovery: therapeutic and clinical trial implications of dysfunctional viable myocardium in heart failure with reduced ejection fraction.

scientific article published on 2 May 2017

Fluid overload in acute heart failure--re-distribution and other mechanisms beyond fluid accumulation

scientific article published on February 2008

Frequency and significance of acute heart failure following liver transplantation

scientific article published in January 2008

Gender Does Not Affect Postdischarge Outcomes in Patients Hospitalized for Worsening Heart Failure With Reduced Ejection Fraction (from the Efficacy of Vasopressin Antagonism in Heart Failure Outcome Study With Tolvaptan [EVEREST] Trial)

article

Geographic variation in heart failure trials: time for scepticism?

scientific article published on 27 May 2014

Global perspectives in hospitalized heart failure: regional and ethnic variation in patient characteristics, management, and outcomes

scientific article published on December 2014

Global variation in clinical profile, management, and post-discharge outcomes among patients hospitalized for worsening chronic heart failure: findings from the ASTRONAUT trial

scientific article published on 30 April 2015

Haemoconcentration, renal function, and post-discharge outcomes among patients hospitalized for heart failure with reduced ejection fraction: insights from the EVEREST trial

scientific article

Haemodynamic effects, safety, and pharmacokinetics of human stresscopin in heart failure with reduced ejection fraction†

Heart failure care in the outpatient cardiology practice setting: findings from IMPROVE HF.

scientific article published on 28 May 2008

Heart failure etiology and response to milrinone in decompensated heart failure: results from the OPTIME-CHF study

scientific article published in March 2003

Heart failure in 2010: one step forward, two steps back

scientific article published on February 2011

Heart failure, chronic diuretic use, and increase in mortality and hospitalization: an observational study using propensity score methods

scientific article published on 18 May 2006

Heart rate: a prognostic factor and therapeutic target in chronic heart failure. The distinct roles of drugs with heart rate-lowering properties

scientific article published on 03 December 2013

Hemoconcentration-guided diuresis in heart failure

scientific article

Hemodynamic, echocardiographic, and neurohormonal effects of istaroxime, a novel intravenous inotropic and lusitropic agent: a randomized controlled trial in patients hospitalized with heart failure

scientific article published on 9 April 2008

Hospitalization for worsening chronic heart failure.

scientific article published on June 2004

Hospitalizations due to unstable angina pectoris in diastolic and systolic heart failure

scientific article published on 21 December 2006

Hospitalizations for Heart Failure in the United States—A Sign of Hope ⬇️

scientific article published on October 19, 2011

Hydralazine and isosorbide dinitrate in heart failure: historical perspective, mechanisms, and future directions

scientific article published on May 2011

Hypercatabolic syndrome: molecular basis and effects of nutritional supplements with amino acids

scientific article published in June 2008

Hyperkalemia in Heart Failure

scientific article

Hyponatremia and in-hospital mortality in patients admitted for heart failure (from the ATTEND registry).

scientific article

Hyponatremia in acute heart failure syndromes: a potential therapeutic target

scientific article published on December 2007

Hyponatremia in heart failure

scientific article published on 29 August 2008

Hyponatremia in patients with heart failure

scientific article

Identifying patients hospitalized with heart failure at risk for unfavorable future quality of life

scientific article

Impact of diabetes on epidemiology, treatment, and outcomes of patients with heart failure

scientific article published on February 2015

Implantable Cardioverter-Defibrillators in Patients Hospitalized for Heart Failure With Chronically Reduced Left Ventricular Ejection Fraction

Implantable cardioverter-defibrillator implementation in acute heart failure syndromes: unanswered questions

scientific article published on September 2011

Importance of in-hospital initiation of evidence-based medical therapies for heart failure-a review

scientific article

Improvement in hyponatremia during hospitalization for worsening heart failure is associated with improved outcomes: insights from the Acute and Chronic Therapeutic Impact of a Vasopressin Antagonist in Chronic Heart Failure (ACTIV in CHF) trial

article

Improvement in the function of hibernating myocardium in a patient with heart failure due to coronary artery disease receiving high-dose simvastatin.

scientific article published in February 2004

Improving Postdischarge Outcomes in Patients Hospitalized for Acute Heart Failure Syndromes ⬇️

scientific article published on June 15, 2011

Improving cardiovascular clinical trials conduct in the United States: recommendation from clinicians, researchers, sponsors, and regulators

scientific article

Improving evidence-based care for heart failure in outpatient cardiology practices: primary results of the Registry to Improve the Use of Evidence-Based Heart Failure Therapies in the Outpatient Setting (IMPROVE HF).

scientific article

Improving outcomes in post-acute myocardial infarction heart failure: incorporation of aldosterone blockade into combination therapy to optimize neurohormonal blockade

scientific article

Improving the Use of Evidence-Based Heart Failure Therapies in the Outpatient Setting: The IMPROVE HF performance improvement registry

article

In response to Nagarajan's letter to the editor “Improvement in ejection fraction—but do not forget the basics, the medications”

In-Hospital Diuretic Agent Use and Post-Discharge Clinical Outcomes in Patients Hospitalized for Worsening Heart Failure: Insights From the EVEREST Trial

scientific article published on 25 March 2016

In-hospital worsening heart failure

scientific article published on 03 August 2015

Incident heart failure hospitalization and subsequent mortality in chronic heart failure: a propensity-matched study

scientific article published on April 2008

Incident heart failure in relation to vascular disease: insights from the Health, Aging, and Body Composition Study

scientific article

Incremental Reduction in Risk of Death Associated With Use of Guideline-Recommended Therapies in Patients With Heart Failure: A Nested Case-Control Analysis of IMPROVE HF

scientific article

Influence of a performance-improvement initiative on quality of care for patients hospitalized with heart failure: results of the Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients With Heart Failure (OPTIMIZE-HF).

scientific article published on July 2007

Influence of atrial fibrillation on post-discharge natriuretic peptide trajectory and clinical outcomes among patients hospitalized for heart failure: insights from the ASTRONAUT trial.

scientific article

Influence of beta-blocker continuation or withdrawal on outcomes in patients hospitalized with heart failure: findings from the OPTIMIZE-HF program

scientific article

Influence of coronary angiography on the utilization of therapies in patients with acute heart failure syndromes: findings from Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients with Heart Failure (OPTIMIZE-HF).

scientific article

Influence of coronary artery disease and coronary revascularization status on outcomes in patients with acute heart failure syndromes: A report from OPTIMIZE-HF (Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients with Heart F

article

Influence of dedicated heart failure clinics on delivery of recommended therapies in outpatient cardiology practices: findings from the Registry to Improve the Use of Evidence-Based Heart Failure Therapies in the Outpatient Setting (IMPROVE HF).

scientific article published in February 2010

Influence of diabetes on characteristics and outcomes in patients hospitalized with heart failure: A report from the Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients with Heart Failure (OPTIMIZE-HF)

article

Influence of diabetes on characteristics and outcomes in patients hospitalized with heart failure: a report from the Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients with Heart Failure (OPTIMIZE-HF).

scientific article published in August 2007

Influence of documented history of coronary artery disease on outcomes in patients admitted for worsening heart failure with reduced ejection fraction in the EVEREST trial

scientific article

Influence of patient age and sex on delivery of guideline-recommended heart failure care in the outpatient cardiology practice setting: findings from IMPROVE HF.

scientific article

Influence of renal function on the use of guideline-recommended therapies for patients with heart failure

scientific article published on 20 February 2010

International REgistry to assess medical Practice with lOngitudinal obseRvation for Treatment of Heart Failure (REPORT-HF): rationale for and design of a global registry

scientific article published on 10 March 2015

International variations in the clinical, diagnostic, and treatment characteristics of emergency department patients with acute heart failure syndromes

scientific article

Intravenous Allogeneic Mesenchymal Stem Cells for Nonischemic Cardiomyopathy: Safety and Efficacy Results of a Phase II-A Randomized Trial

scientific article

Introduction

Introduction

Introduction to ACCORD-PMI: the Advisory Council on Care Optimization to Reduce Death Post-MI.

scientific article

Introduction to acute heart failure syndromes

scientific article published in September 2005

Iron status in patients with chronic heart failure

scientific article published on 23 November 2012

Is hospital admission for heart failure really necessary?: the role of the emergency department and observation unit in preventing hospitalization and rehospitalization

scientific article

Is there a clinically meaningful difference in patient reported dyspnea in acute heart failure? An analysis from URGENT Dyspnea

scientific article published on 19 April 2017

Is thrombosis a contributor to heart failure pathophysiology? Possible mechanisms, therapeutic opportunities, and clinical investigation challenges

scientific article published on 06 January 2013

Istaroxime, a first in class new chemical entity exhibiting SERCA-2 activation and Na-K-ATPase inhibition: a new promising treatment for acute heart failure syndromes?

scientific article published on 24 February 2009

Lack of evidence of increased mortality among patients with atrial fibrillation taking digoxin: findings from post hoc propensity-matched analysis of the AFFIRM trial

scientific article published on 16 April 2013

Learning from recent trials and shaping the future of acute heart failure trials

scientific article published on 13 September 2013

Left ventricular dysfunction with pulmonary hypertension: part 2: prognosis, noninvasive evaluation, treatment, and future research

scientific article published on May 2013

Length of hospital stay and 30-day readmission following heart failure hospitalization: insights from the EVEREST trial

scientific article published on 9 May 2015

Letter by Abu Daya et al Regarding Article, "Myocardial Stiffness in Patients With Heart Failure and a Preserved Ejection Fraction, Contributions of Collagen and Titin".

scientific article published in November 2015

Lipids, statins, and clinical outcomes in heart failure: rethinking the data

scientific article

Lower serum sodium is associated with increased short-term mortality in hospitalized patients with worsening heart failure: results from the Outcomes of a Prospective Trial of Intravenous Milrinone for Exacerbations of Chronic Heart Failure (OPTIME-

scientific article published on 2 May 2005

Managed care interventions for improving outcomes in acute heart failure syndromes

scientific article published on December 2008

Management of post-myocardial infarction patients with left ventricular systolic dysfunction

scientific article published on February 2007

Management of the patient with diabetes mellitus and myocardial infarction: clinical trials update

scientific article (publication date: 8 March 2004)

Mechanical circulatory support devices for acute heart failure syndromes: considerations for clinical trial design

scientific article published on 12 June 2008

Mechanisms Contributing to the Progression of Ischemic and Nonischemic Dilated Cardiomyopathy: Possible Modulating Effects of Paracrine Activities of Stem Cells

scientific article

Medication dosing in outpatients with heart failure after implementation of a practice-based performance improvement intervention: findings from IMPROVE HF.

scientific article published on 19 September 2011

Micronutrient deficiencies an unmet need in heart failure

scientific article

Mineralocorticoid receptor antagonism: therapeutic potential in acute heart failure syndromes ⬇️

scientific article published on June 14, 2011

Mineralocorticoid receptor antagonist use in hospitalized patients with heart failure, reduced ejection fraction, and diabetes mellitus (from the EVEREST Trial)

scientific article

Mineralocorticoid receptor antagonists for heart failure with reduced ejection fraction: integrating evidence into clinical practice

scientific article published on 31 August 2012

Mitochondria as a Therapeutic Target in Heart Failure ⬇️

scientific article published on December 5, 2012

Mitral regurgitation in chronic heart failure: more questions than answers?

scientific article published on March 2004

Mode of Death in Heart Failure With Preserved Ejection Fraction

scientific article

Molecular and cellular basis of viable dysfunctional myocardium

scientific article

Myocardial Fibrosis Quantified by Extracellular Volume Is Associated With Subsequent Hospitalization for Heart Failure, Death, or Both Across the Spectrum of Ejection Fraction and Heart Failure Stage

scientific article published on 18 December 2015

Myocardial damage detected by late gadolinium enhancement cardiovascular magnetic resonance is associated with subsequent hospitalization for heart failure

scientific article

Myocardial fibrosis is associated with subsequent death and hospitalization for heart failure in obese adults.

scientific article published on 3 February 2015

National Heart, Lung, and Blood Institute working group on emergency department management of acute heart failure: research challenges and opportunities

scientific article

Natriuretic peptide-guided management in heart failure

scientific article published on 22 April 2016

Natriuretic peptide-guided management in heart failure

scientific article

Need for increased awareness and evidence-based therapies for patients hospitalized for heart failure

scientific article published in November 2013

Neurohormonal inhibition in heart failure: insights from recent clinical trials

scientific article

New insights into diastolic heart failure: role of diabetes mellitus

scientific article published on March 2004

New strategies for heart failure with preserved ejection fraction: the importance of targeted therapies for heart failure phenotypes

scientific article

Nitrate therapy for heart failure: benefits and strategies to overcome tolerance

scientific article published on 3 June 2013

Normalization of ejection fraction and resolution of symptoms in chronic severe heart failure is possible with modern medical therapy: clinical observations in 11 patients

scientific article published in May 2008

Novel Endpoints for Heart Failure Clinical Trials

scientific article

Nutritional assessment and support of the patient with acute heart failure ⬇️

scientific article published on October 1, 2010

OPTIME in CHF trial: rethinking the use of inotropes in the management of worsening chronic heart failure resulting in hospitalization

scientific article

Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients with Heart Failure (OPTIMIZE-HF): rationale and design

scientific article

Outpatient cardiology practices with advanced practice nurses and physician assistants provide similar delivery of recommended therapies (findings from IMPROVE HF).

scientific article published on 4 May 2010

Overview of current noninodilator therapies for acute heart failure syndromes

scientific article

Overview of emerging pharmacologic agents for acute heart failure syndromes

scientific article published on February 2008

Overview of vasopressin receptor antagonists in heart failure resulting in hospitalization

scientific article

Partial Adenosine A1 Agonist in Heart Failure

scientific article

Partial adenosine A1 receptor agonism: a potential new therapeutic strategy for heart failure

scientific article published on 23 December 2015

Past, present, and future of acute heart failure clinical trials-a high-risk population in search of a strategy

scientific article published on 18 September 2017

Pathophysiologic targets in the early phase of acute heart failure syndromes

scientific article

Patient-reported outcomes in the SOluble guanylate Cyclase stimulatoR in heArT failurE patientS with PRESERVED ejection fraction (SOCRATES-PRESERVED) study

scientific article published in June 2017

Pharmacokinetics and pharmacodynamics of rivaroxaban and its effect on biomarkers of hypercoagulability in patients with chronic heart failure

article

Pharmacologic therapy for patients with chronic heart failure and reduced systolic function: review of trials and practical considerations

scientific article

Pharmacological treatment of chronic heart failure

scientific article published on June 2006

Pharmacology of new agents for acute heart failure syndromes

scientific article

Phase II trials in heart failure: the role of cardiovascular imaging

scientific article published on July 2011

Phase III clinical trial end points in acute heart failure syndromes: A virtual roundtable with the acute heart failure syndromes international working group

article

Phenomapping for novel classification of heart failure with preserved ejection fraction

scientific article

Practical recommendations for prehospital and early in-hospital management of patients presenting with acute heart failure syndromes

scientific article published on January 2008

Pre-discharge and early post-discharge troponin elevation among patients hospitalized for heart failure with reduced ejection fraction: findings from the ASTRONAUT trial

scientific article published on 17 October 2017

Predictive Value of Low Relative Lymphocyte Count in Patients Hospitalized for Heart Failure With Reduced Ejection Fraction

article

Predictors of Delivery of Hospital-Based Heart Failure Patient Education: A Report from OPTIMIZE-HF

article

Predictors of in-hospital mortality in patients hospitalized for heart failure: insights from the Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients with Heart Failure (OPTIMIZE-HF).

scientific article published in July 2008

Predictors of mortality after discharge in patients hospitalized with heart failure: an analysis from the Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients with Heart Failure (OPTIMIZE-HF).

scientific article published in October 2008

Predischarge initiation of carvedilol in patients hospitalized for decompensated heart failure: results of the Initiation Management Predischarge: Process for Assessment of Carvedilol Therapy in Heart Failure (IMPACT-HF) trial

scientific article published in May 2004

Prevalence of myocardial viability in dysfunctional areas by cardiovascular magnetic resonance in patients with coronary artery disease.

scientific article published on 2 February 2011

Prevalence, clinical phenotype, and outcomes associated with normal B-type natriuretic peptide levels in heart failure with preserved ejection fraction

scientific article

Prevention and management of chronic heart failure in patients at risk

scientific article

Prognostic Value of Blood Urea Nitrogen in Patients Hospitalized With Worsening Heart Failure: Insights From the Acute and Chronic Therapeutic Impact of a Vasopressin Antagonist in Chronic Heart Failure (ACTIV in CHF) Study

article

Prognostic Value of Monocyte Count in Patients Hospitalized for Heart Failure With Reduced Ejection Fraction (from the EVEREST Trial)

Prognostic implications of renal dysfunction in patients hospitalized with heart failure: data from the last decade of clinical investigations

scientific article

Prognostic markers in heart failure--congestion, neurohormones, and the cardiorenal syndrome

scientific article published on January 2007

Prognostic role of N-terminal pro-brain natriuretic peptide in asymptomatic hypertensive and diabetic patients in primary care: impact of age and gender : Results from the PROBE-HF study

scientific article published on 7 November 2015

Prognostic significance of serum total cholesterol and triglyceride levels in patients hospitalized for heart failure with reduced ejection fraction (from the EVEREST Trial).

scientific article

Progress or lack of progress in hospitalized heart failure.

scientific article published in September 2013

Prospective evaluation of beta-blocker use at the time of hospital discharge as a heart failure performance measure: results from OPTIMIZE-HF.

scientific article published in November 2007

Protein turnover in the failing heart: an ever-changing landscape

scientific article published on 14 August 2017

Quality of care of and outcomes for African Americans hospitalized with heart failure: findings from the OPTIMIZE-HF (Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients With Heart Failure) registry

scientific article published in April 2008

Race and improvements in the use of guideline-recommended therapies for patients with heart failure: findings from IMPROVE HF.

scientific article published in May 2012

Racial differences in the characteristics of patients admitted for acute decompensated heart failure and their relation to outcomes: results from the OPTIME-CHF trial

scientific article published in December 2006

Rationale and design of ARTS: a randomized, double-blind study of BAY 94-8862 in patients with chronic heart failure and mild or moderate chronic kidney disease

scientific article published in June 2012

Rationale and design of MinerAlocorticoid Receptor antagonist Tolerability Study-Heart Failure (ARTS-HF): a randomized study of finerenone vs. eplerenone in patients who have worsening chronic heart failure with diabetes and/or chronic kidney diseas

scientific article

Rationale and design of a randomized controlled trial of allogeneic mesenchymal stem cells in patients with nonischemic cardiomyopathy

scientific article published on 13 October 2015

Rationale and design of a randomized, double-blind, event-driven, multicentre study comparing the efficacy and safety of oral rivaroxaban with placebo for reducing the risk of death, myocardial infarction or stroke in subjects with heart failure and

scientific article published on 27 April 2015

Rationale and design of the Initiation Management Predischarge: Process for Assessment of Carvedilol Therapy for Heart Failure (IMPACT-HF) study

scientific article published in February 2003

Rationale and design of the SOluble guanylate Cyclase stimulatoR in heArT failurE Studies (SOCRATES).

scientific article published on 24 July 2014

Rationale and design of the hemodynamic, echocardiographic and neurohormonal effects of istaroxime, a novel intravenous inotropic and lusitropic agent: a randomized controlled trial in patients hospitalized with heart failure (HORIZON-HF) trial

scientific article published in May 2008

Rationale and design of the multicenter, randomized, double-blind, placebo-controlled study to evaluate the Efficacy of Vasopressin antagonism in Heart Failure: Outcome Study with Tolvaptan (EVEREST).

scientific article published in May 2005

Rationale and design of the multicentre, randomized, double‐blind, placebo‐controlled Aliskiren Trial on Acute Heart Failure Outcomes (ASTRONAUT) ⬇️

scientific article published on November 30, 2010

Rationale and design of the phase 2b clinical trials to study the effects of the partial adenosine A1-receptor agonist neladenoson bialanate in patients with chronic heart failure with reduced (PANTHEON) and preserved (PANACHE) ejection fraction

scientific article published on 17 September 2018

Rationale and design of the pilot randomized study of nesiritide versus dobutamine in heart failure (PRESERVD-HF).

scientific article published in February 2003

Rationale and study design for a multicenter, randomized, double-blind, placebo-controlled study of the effects of tolvaptan on the acute and chronic outcomes of patients hospitalized with worsening congestive heart failure

scientific article published in February 2003

Rationale, design, and results from RENO-DEFEND 1: a randomized, dose-finding study of the selective A1 adenosine antagonist SLV320 in patients hospitalized with acute heart failure

scientific article published in June 2011

Reappraisal of beta-blocker therapy in the acute and chronic post-myocardial infarction period

scientific article published on January 1, 2003

Reassessing Phase II Heart Failure Clinical Trials: Consensus Recommendations

scientific article published on April 2017

Reassessing the use of vasodilators in heart failure ⬇️

scientific article published on September 1, 2012

Reassessment of dobutamine, dopamine, and milrinone in the management of acute heart failure syndromes

scientific article

Recognizing hospitalized heart failure as an entity and developing new therapies to improve outcomes: academics', clinicians', industry's, regulators', and payers' perspectives

scientific article published on July 2013

Redefining the role of biomarkers in heart failure trials: expert consensus document

scientific article published on 23 March 2017

Regional Validation and Recalibration of Clinical Predictive Models for Patients With Acute Heart Failure.

scientific article

Rehospitalization for heart failure: problems and perspectives

scientific article published on 5 December 2012

Relation between contractile reserve and improvement in left ventricular function with beta-blocker therapy in patients with heart failure secondary to ischemic or idiopathic dilated cardiomyopathy

scientific article published in April 2004

Relation of low hemoglobin and anemia to morbidity and mortality in patients hospitalized with heart failure (insight from the OPTIMIZE-HF registry).

scientific article published in January 2008

Relation of serum magnesium levels and postdischarge outcomes in patients hospitalized for heart failure (from the EVEREST Trial).

scientific article

Relation of serum uric acid levels and outcomes among patients hospitalized for worsening heart failure with reduced ejection fraction (from the efficacy of vasopressin antagonism in heart failure outcome study with tolvaptan trial).

scientific article published on 16 September 2014

Relationship between clinical trial site enrollment with participant characteristics, protocol completion, and outcomes: insights from the EVEREST (Efficacy of Vasopressin Antagonism in Heart Failure: Outcome Study with Tolvaptan) trial

scientific article published on 12 December 2012

Renin-angiotensin blockade in heart failure with preserved ejection fraction: a systematic review and meta-analysis

scientific article published on 4 September 2017

Reply

Reply to letter to the editor by Shiraishi and colleagues.

scientific article

Reply: To PMID 23273288.

scientific article published on 28 March 2013

Reply: effect of ivabradine on early readmissions after hospitalization for worsening heart failure

scientific article published in March 2015

Response to the Letter of Hester Den Ruijter and Ruben Coronel Regarding the Article “The Role of n-3 PUFAs in Preventing the Arrhythmic Risk in Patients with Idiopathic Dilated Cardiomyopathy”

Resting heart rate and risk of incident heart failure: three prospective cohort studies and a systematic meta-analysis

scientific article

Return of digoxin and recovery of renal function

scientific article

Review of current and investigational pharmacologic agents for acute heart failure syndromes

scientific article published on 27 November 2006

Revisiting cardiac injury during acute heart failure: further characterization and a possible target for therapy

scientific article

Risk Stratification

article

Risk stratification after hospitalization for decompensated heart failure

scientific article published in December 2004

Rivaroxaban in Patients with Heart Failure, Sinus Rhythm, and Coronary Disease

article by Faiez Zannad et al published 4 October 2018 in The New England Journal of Medicine

Roadmap to inpatient heart failure management

scientific article

Role of beta-blocker therapy in the post-myocardial infarction patient with and without left ventricular dysfunction

scientific article published on January 1, 2003

Role of carvedilol in atrial fibrillation: insights from clinical trials

scientific article published on May 2004

Role of guanylate cyclase modulators in decompensated heart failure

scientific article published on December 2009

Role of neurohormonal modulators in heart failure with relatively preserved systolic function

scientific article published on 7 January 2005

Role of neurohormonal modulators in heart failure with relatively preserved systolic function

scientific article published in February 2008

Role of vasopressin antagonists in the management of acute decompensated heart failure

scientific article

Role of β-Blocker Therapy in the Postmyocardial Infarction Patient With and Without Left Ventricular Dysfunction Consensus Guideline

Safety and Tolerability of Neladenoson Bialanate, a Novel Oral Partial Adenosine A1 Receptor Agonist, in Patients With Chronic Heart Failure

scientific article published on 14 September 2016

Safety and tolerability of the novel non-steroidal mineralocorticoid receptor antagonist BAY 94-8862 in patients with chronic heart failure and mild or moderate chronic kidney disease: a randomized, double-blind trial

scientific article published on 27 May 2013

Seeking new heights in acute heart failure syndromes: lessons from ASCEND and EVEREST.

scientific article

Serum Osmolality and Postdischarge Outcomes After Hospitalization for Heart Failure

scientific article published on 14 January 2016

Serum aldosterone is associated with mortality and re-hospitalization in patients with reduced ejection fraction hospitalized for acute heart failure: analysis from the EVEREST trial

scientific article

Serum insulin-like growth factor-1 and its binding protein-7: potential novel biomarkers for heart failure with preserved ejection fraction

scientific article

Short-term clinical effects of tolvaptan, an oral vasopressin antagonist, in patients hospitalized for heart failure: the EVEREST Clinical Status Trials

scientific article

Short-term intravenous milrinone for acute exacerbation of chronic heart failure: a randomized controlled trial

scientific article published in March 2002

Site selection for heart failure clinical trials in the USA.

scientific article published in July 2015

Site selection in global clinical trials in patients hospitalized for heart failure: perceived problems and potential solutions

scientific article

Society of Chest Pain Centers recommendations for the evaluation and management of the observation stay acute heart failure patient-parts 1-6.

scientific article published on January 2009

Soluble guanylate cyclase: a potential therapeutic target for heart failure

scientific article published on March 2013

Special cases in acute heart failure syndromes: atrial fibrillation and wide complex tachycardia

scientific article published on January 2009

Spectrum of epidemiological and clinical findings in patients with heart failure with preserved ejection fraction stratified by study design: a systematic review

scientific article

Standardized Reporting Criteria for Studies Evaluating Suspected Acute Heart Failure Syndromes in the Emergency Department

Strategies and Opportunities for Drug Development in Heart Failure

scientific article published in The Journal of the American Medical Association

Strategies to reduce heart failure readmissions--reply

scientific article published in March 2014

Sudden Death After Hospitalization for Heart Failure With Reduced Ejection Fraction (from the EVEREST Trial)

Surrogate end points in heart failure trials

scientific article published in February 2003

Systolic Blood Pressure and Outcomes in Patients Hospitalized With Acute Heart Failure—Reply

scientific article published in The Journal of the American Medical Association

Systolic blood pressure at admission, clinical characteristics, and outcomes in patients hospitalized with acute heart failure

scientific article

Targeting digoxin dosing to serum concentration: is the bullseye too small?

scientific article published in August 2016

Targeting myocardial substrate metabolism in heart failure: potential for new therapies

scientific article

Temporal Changes in Postdischarge Mortality Risk After Hospitalization for Heart Failure (from the EVEREST Trial).

scientific article published on 8 December 2015

Temporal Relation Between Myocardial Fibrosis and Heart Failure With Preserved Ejection Fraction: Association With Baseline Disease Severity and Subsequent Outcome

scientific article

Tezosentan in patients with acute heart failure and acute coronary syndromes: design of the Randomized Intravenous Tezosentan study (RITZ-4).

scientific article published in October 2002

Tezosentan in patients with acute heart failure and acute coronary syndromes: design of the fourth Randomized Intravenous Tezosentan Study (RITZ-4).

scientific article published in February 2003

Tezosentan in patients with acute heart failure and acute coronary syndromes: results of the Randomized Intravenous TeZosentan Study (RITZ-4).

scientific article published in May 2003

The Authors' reply: Figure 1

The Impact of Chronic Obstructive Pulmonary Disease in Patients Hospitalized for Worsening Heart Failure With Reduced Ejection Fraction: An Analysis of the EVEREST Trial

article

The Initiation Management Predischarge Process for Assessment of Carvedilol Therapy for Heart Failure (IMPACT-HF) Study: design and implications

scientific article published on January 2002

The Pilot Randomized Study of Nesiritide Versus Dobutamine in Heart Failure (PRESERVD-HF).

scientific article published in September 2005

The Reply

The Valsalva maneuver: a bedside "biomarker" for heart failure

scientific article

The Worst Symptom as Defined By Patients During Heart Failure Hospitalization: Implications for Response to Therapy ⬇️

scientific article published on May 30, 2012

The burden of acute heart failure on U.S. emergency departments

scientific article published on 30 April 2014

The challenge of acute decompensated heart failure

scientific article published on June 2006

The challenge of acute heart failure syndromes

scientific article

The current and future management of acute heart failure syndromes

scientific article published on 05 March 2010

The diabetes epidemic: a national and global crisis

scientific article published on March 2004

The disconnect between phase II and phase III trials of drugs for heart failure

scientific article published on 08 January 2013

The effects of eplerenone on length of stay and total days of heart failure hospitalization after myocardial infarction in patients with left ventricular systolic dysfunction

scientific article published in September 2009

The global health and economic burden of hospitalizations for heart failure: lessons learned from hospitalized heart failure registries.

scientific article

The immunological axis in heart failure: importance of the leukocyte differential

scientific article

The impact of arrhythmias in acute heart failure

scientific article

The impact of coronary artery disease on outcomes after liver transplantation

scientific article published on 16 December 2014

The impact of early standard therapy on dyspnoea in patients with acute heart failure: the URGENT-dyspnoea study

scientific article published on 11 November 2009

The past, present and future of renin-angiotensin aldosterone system inhibition

scientific article

The potential application of electrophysiology diagnostics and therapeutics in acute heart failure syndromes

The potential role of cardiac resynchronization therapy in acute heart failure syndromes ⬇️

scientific article published on September 1, 2011

The potential role of nonpharmacologic electrophysiology-based interventions in improving outcomes in patients hospitalized for heart failure

scientific article published on July 2013

The predictive value of transaminases at admission in patients hospitalized for heart failure: findings from the RO-AHFS registry

scientific article published on June 2013

The problem of decompensated heart failure: nomenclature, classification, and risk stratification

scientific article

The prognostic significance of heart rate in patients hospitalized for heart failure with reduced ejection fraction in sinus rhythm: insights from the EVEREST (Efficacy of Vasopressin Antagonism in Heart Failure: Outcome Study With Tolvaptan) trial.

scientific article

The role of N-terminal PRO-brain natriuretic peptide and echocardiography for screening asymptomatic left ventricular dysfunction in a population at high risk for heart failure. The PROBE-HF study

scientific article published on 21 January 2009

The role of echocardiography in the diagnosis and management of heart failure

scientific article

The role of n-3 PUFAs in preventing the arrhythmic risk in patients with idiopathic dilated cardiomyopathy

scientific article

The role of the emergency department in acute heart failure clinical trials--enriching patient identification and enrollment

scientific article published on 18 April 2013

The role of the kidney in heart failure

scientific article

The underuse of digoxin in heart failure, and approaches to appropriate use.

scientific article published on February 2007

The use of digoxin in patients with worsening chronic heart failure: reconsidering an old drug to reduce hospital admissions

scientific article

The vulnerable phase after hospitalization for heart failure

scientific article published on 10 February 2015

Therapeutic targets in heart failure: refocusing on the myocardial interstitium

scientific article published on 19 March 2014

Therapy for acute heart failure syndromes

scientific article published on May 2009

Think Small and Examine the Constituents of Left Ventricular Hypertrophy and Heart Failure: Cardiomyocytes Versus Fibroblasts, Collagen, and Capillaries in the Interstitium

scientific article published on 15 September 2015

Third Universal Definition of Myocardial Infarction

article

Third universal definition of myocardial infarction

scientific article

Thirty-day readmissions: the clock is ticking

scientific article published in January 2013

Timing and duration of interventions in clinical trials for patients with hospitalized heart failure

scientific article published on September 2013

Tolvaptan for the treatment of heart failure: a review of the literature ⬇️

scientific article published on March 15, 2011

Tolvaptan for the treatment of hyponatremia and congestive heart failure

scientific article published on November 2006

Tolvaptan for the treatment of hyponatremia secondary to the syndrome of inappropriate antidiuretic hormone secretion ⬇️

scientific article published on December 1, 2011

Tolvaptan, a selective oral vasopressin V2-receptor antagonist, for hyponatremia

scientific article

Tolvaptan: a selective vasopressin type 2 receptor antagonist in congestive heart failure

scientific article

Transatlantic similarities and differences in major natural history endpoints of heart failure after acute myocardial infarction: a propensity-matched study of the EPHESUS trial

scientific article

Translating the basic knowledge of mitochondrial functions to metabolic therapy: role of L-carnitine

scientific article

Treatment gaps in the pharmacologic management of heart failure.

scientific article

Trends in Heart Failure Clinical Trials From 2001-2012.

scientific article published on 21 June 2015

Trends in Utilization of Surrogate Endpoints in Contemporary Cardiovascular Clinical Trials

scientific article published on 19 March 2016

Trends in characteristics of cardiovascular clinical trials 2001-2012.

scientific article published on 14 May 2015

Troponin elevation in heart failure prevalence, mechanisms, and clinical implications

scientific article published on September 2010

Troponin elevation in patients with heart failure: on behalf of the third Universal Definition of Myocardial Infarction Global Task Force: Heart Failure Section

scientific article

Use and impact of inotropes and vasodilator therapy in hospitalized patients with severe heart failure

scientific article published in January 2007

Use of hand carried ultrasound, B-type natriuretic peptide, and clinical assessment in identifying abnormal left ventricular filling pressures in patients referred for right heart catheterization

scientific article published on 26 September 2009

Usefulness of Electrocardiographic QT Interval to Predict Left Ventricular Diastolic Dysfunction ⬇️

scientific article published on September 10, 2011

Usefulness of an elevated troponin-I in predicting clinical events in patients admitted with acute heart failure and acute coronary syndrome (from the RITZ-4 trial).

scientific article

Usefulness of anemia as a predictor of death and rehospitalization in patients with decompensated heart failure

scientific article published in September 2003

Using Natriuretic Peptides for Selection of Patients in Acute Heart Failure Clinical Trials

scientific article published on 29 July 2015

Utility of positron emission tomography for drug development for heart failure

scientific article published on 27 February 2016

Vasopressin V2 Receptor Blockade With Tolvaptan Versus Fluid Restriction in the Treatment of Hyponatremia

article

Vasopressin V2-receptor blockade with tolvaptan in patients with chronic heart failure: results from a double-blind, randomized trial

scientific article (publication date: 3 June 2003)

Vasopressin and vasopressin antagonists in heart failure and hyponatremia

scientific article published on June 2008

Vasopressin antagonism in heart failure

scientific article

Vasopressin antagonists in the management of heart failure

scientific article published on March 2007

Vasopressin receptor antagonists for the treatment of hyponatremia: systematic review and meta-analysis

scientific article published on 09 June 2010

Vasopressin: a new target for the treatment of heart failure

scientific article

Vericiguat in patients with worsening chronic heart failure and preserved ejection fraction: results of the SOluble guanylate Cyclase stimulatoR in heArT failurE patientS with PRESERVED EF (SOCRATES-PRESERVED) study

scientific article

Water and sodium in heart failure: a spotlight on congestion

scientific article published on January 2015

Weight changes after hospitalization for worsening heart failure and subsequent re-hospitalization and mortality in the EVEREST trial.

scientific article published on 2 May 2009

Why, when, and how to assess pulmonary congestion in heart failure: pathophysiological, clinical, and methodological implications

scientific article published on January 2010

n-3 polyunsaturated fatty acids in the prevention of atrial fibrillation recurrences after electrical cardioversion: a prospective, randomized study

scientific article published on 15 August 2011

patient and practice factors associated with improvement in use of guideline-recommended therapies for outpatients with heart failure (from the IMPROVE HF trial).

scientific article published in January 2011

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