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List of works by Justin Jang Hann Chu

A flavonoid compound library screen revealed potent antiviral activity of plant-derived flavonoids on human enterovirus A71 replication

scientific article published on 9 December 2017

A novel DANP-coupled hairpin RT-PCR for rapid detection of Chikungunya virus

scientific article published on 9 January 2013

A polarized cell model for Chikungunya virus infection: entry and egress of virus occurs at the apical domain of polarized cells

scientific article (publication date: February 2014)

A potent neutralizing IgM mAb targeting the N218 epitope on E2 protein protects against Chikungunya virus pathogenesis

scientific article

Activation of TLR2 and TLR6 by Dengue NS1 Protein and Its Implications in the Immunopathogenesis of Dengue Virus Infection

scientific article published on 30 July 2015

Activity of andrographolide against chikungunya virus infection

scientific article

Adaptor Protein 1A Facilitates Dengue Virus Replication

scientific article published on 19 June 2015

Adenovirus vectored IFN-α protects mice from lethal challenge of Chikungunya virus infection

scientific article published on 03 December 2020

An evaluation of Chloroquine as a broad-acting antiviral against Hand, Foot and Mouth Disease

scientific article

Anti-Chikungunya viral activities of aplysiatoxin-related compounds from the marine cyanobacterium Trichodesmium erythraeum ⬇️

scientific article published on 03 January 2014

Antiviral Phosphorodiamidate Morpholino Oligomers are Protective against Chikungunya Virus Infection on Cell-based and Murine Models

scientific article

Antiviral activities of 15 dengue NS2B-NS3 protease inhibitors using a human cell-based viral quantification assay

scientific article

Antiviral activities of peptide-based covalent inhibitors of the Enterovirus 71 3C protease

scientific article published on 20 September 2016

Antiviral activity of lanatoside C against dengue virus infection

scientific article

Antiviral activity of selected flavonoids against Chikungunya virus

scientific article published on 23 July 2016

Antiviral activity of silymarin against chikungunya virus

scientific article published on 16 June 2015

Bortezomib inhibits chikungunya virus replication by interfering with viral protein synthesis

scientific article published on 29 May 2020

Cellular vimentin regulates construction of dengue virus replication complexes through interaction with NS4A protein

scientific article

Characterization of RyDEN (C19orf66) as an Interferon-Stimulated Cellular Inhibitor against Dengue Virus Replication

scientific journal article

Characterization of oral virome and microbiome revealed distinctive microbiome disruptions in paediatric patients with hand, foot and mouth disease

scientific article published on 19 February 2021

Chikungunya virus: an update on antiviral development and challenges

scientific article published on 15 May 2013

Circulating Salivary miRNA hsa-miR-221 as Clinically Validated Diagnostic Marker for Hand, Foot, and Mouth Disease in Pediatric Patients.

scientific article published on 10 May 2018

Comparative analysis of the genome sequences and replication profiles of chikungunya virus isolates within the East, Central and South African (ECSA) lineage

scientific article published on 30 May 2013

Cytokine and Chemokine Profiling in Patients with Hand, Foot and Mouth Disease in Singapore and Malaysia.

scientific article

Dengue virus infection mediates HMGB1 release from monocytes involving PCAF acetylase complex and induces vascular leakage in endothelial cells

scientific article

Dengue virus-infected human monocytes trigger late activation of caspase-1, which mediates pro-inflammatory IL-1β secretion and pyroptosis

scientific article published on 24 July 2013

Development and Evaluation of a SYBR Green-Based Real-Time Multiplex RT-PCR Assay for Simultaneous Detection and Serotyping of Dengue and Chikungunya Viruses

scientific article published on November 2015

Development of 2, 7-Diamino-1, 8-Naphthyridine (DANP) Anchored Hairpin Primers for RT-PCR Detection of Chikungunya Virus Infection

scientific article

Developments towards antiviral therapies against enterovirus 71 ⬇️

scientific article published on October 23, 2010

Diagnosis of human enteroviruses that cause hand, foot and mouth disease

scientific article published on 4 April 2016

Differential regulation of angiopoietin 1 and angiopoietin 2 during dengue virus infection of human umbilical vein endothelial cells: implications for endothelial hyperpermeability

scientific article published on 30 August 2013

Discovery of selective dengue virus inhibitors using combination of molecular fingerprint-based virtual screening protocols, structure-based pharmacophore model development, molecular dynamics simulations and in vitro studies

scientific article published on 9 August 2017

Discovery of selective dengue virus inhibitors using combination of molecular fingerprint-based virtual screening protocols, structure-based pharmacophore model development, molecular dynamics simulations and in vitro studies

scientific article published on 24 October 2017

Enteroviral 3C protease activates the human NLRP1 inflammasome in airway epithelia

scientific article published on 22 October 2020

Establishment of a Novel Primary Human Skeletal Myoblast Cellular Model for Chikungunya Virus Infection and Pathogenesis

scientific article published on 19 February 2016

Establishment of one-step SYBR green-based real time-PCR assay for rapid detection and quantification of chikungunya virus infection

scientific article (publication date: 21 January 2010)

Expression of plasmid-based shRNA against the E1 and nsP1 genes effectively silenced Chikungunya virus replication

scientific article

GNF-2 Inhibits Dengue Virus by Targeting Abl Kinases and the Viral E Protein

scientific article

Infectious Viral Quantification of Chikungunya Virus-Virus Plaque Assay

scientific article published on January 2016

Inhibition of chikungunya virus replication by harringtonine, a novel antiviral that suppresses viral protein expression

scientific article

Inhibition of enterovirus VP4 myristoylation is a potential antiviral strategy for hand, foot and mouth disease

scientific article published on 9 August 2016

Macropinocytosis dependent entry of Chikungunya virus into human muscle cells

scientific article published on 26 August 2019

Molecular profiling of T-helper immune genes during dengue virus infection

scientific article

Mosquito cellular factors and functions in mediating the infectious entry of chikungunya virus

scientific article

Narasin, a novel antiviral compound that blocks dengue virus protein expression

scientific article

Natural compounds inhibiting the replication of Porcine reproductive and respiratory syndrome virus ⬇️

scientific article published on April 3, 2012

Natural products as Zika antivirals

scientific article published in 2022

Oligopolyphenylenevinylene-conjugated oligoelectrolyte membrane insertion molecules selectively disrupt cell envelopes of Gram-positive bacteria

scientific article

Photodynamic inactivation of viruses using upconversion nanoparticles ⬇️

scientific article published on 05 December 2011

Prohibitin plays a critical role in Enterovirus 71 neuropathogenesis

scientific article published on 11 January 2018

Propagation of Chikungunya Virus Using Mosquito Cells

scientific article published on January 2016

Proteomic profiling of chikungunya virus-infected human muscle cells: reveal the role of cytoskeleton network in CHIKV replication

scientific article

Proteomics profiling of chikungunya-infected Aedes albopictus C6/36 cells reveal important mosquito cell factors in virus replication

scientific article

RNAi screen reveals a role of SPHK2 in dengue virus-mediated apoptosis in hepatic cell lines

scientific article published on 16 November 2017

Recent advances in therapeutic recruitment of mammalian RNAi and bacterial CRISPR-Cas DNA interference pathways as emerging antiviral strategies

scientific article

Recent advances on the role of host factors during non-poliovirus enteroviral infections

scientific article published on 19 June 2019

Replication of alphaviruses: a review on the entry process of alphaviruses into cells

scientific article

Reverse Genetics Approaches for Chikungunya Virus

scientific article published on January 2016

Single dose of an adenovirus vectored mouse interferon-α protects mice from lethal EV71 challenge

scientific article published on 10 September 2016

Sinovac EV71 vaccine: the silver bullet for hand, foot and mouth disease—or not?

scholarly article published 9 January 2017

Small interference RNA profiling reveals the essential role of human membrane trafficking genes in mediating the infectious entry of dengue virus

scientific article (publication date: February 2010)

The Interplay of Viral and Host Factors in Chikungunya Virus Infection: Targets for Antiviral Strategies

scholarly article by Kai Zhi Wong published in May 2018

The essential role of clathrin-mediated endocytosis in the infectious entry of human enterovirus 71.

scientific article

The role of Misshapen NCK-related kinase (MINK), a novel Ste20 family kinase, in the IRES-mediated protein translation of human enterovirus 71.

scientific article

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