List of works - Alfonso Martinez Arias

A Sprouty4 reporter to monitor FGF/ERK signaling activity in ESCs and mice

scientific article published on 30 June 2018

A competitive protein interaction network buffers Oct4-mediated differentiation to promote pluripotency in embryonic stem cells

scientific article published on 8 October 2013

A draft map of the mouse pluripotent stem cell spatial proteome

scientific article published on 12 January 2016

A membrane-associated β-catenin/Oct4 complex correlates with ground-state pluripotency in mouse embryonic stem cells

scientific article published on March 2013

A molecular basis for developmental plasticity in early mammalian embryos

scientific article published on September 2013

A new dawn for an old connection: development meets the cell

scientific article published in July 2002

An epiblast stem cell-derived multipotent progenitor population for axial extension

scientific article published on 20 May 2019

An in vitro model of early anteroposterior organization during human development

scientific article published on 11 June 2020

An interplay between extracellular signalling and the dynamics of the exit from pluripotency drives cell fate decisions in mouse ES cells

scientific article published on 20 June 2014

Anteroposterior polarity and elongation in the absence of extra-embryonic tissues and of spatially localised signalling in gastruloids: mammalian embryonic organoids

scientific article published on 26 September 2017

Armadillo/beta-catenin-dependent Wnt signalling is required for the polarisation of epidermal cells during dorsal closure in Drosophila

scientific article

Axis Specification in Zebrafish Is Robust to Cell Mixing and Reveals a Regulation of Pattern Formation by Morphogenesis

scientific article published on 12 June 2020

Axis Specification in Zebrafish Is Robust to Cell Mixing and Reveals a Regulation of Pattern Formation by Morphogenesis

scientific article published on 01 August 2020

Brachyury cooperates with Wnt/β-catenin signalling to elicit primitive-streak-like behaviour in differentiating mouse embryonic stem cells

scientific article (publication date: 13 August 2014)

Building and engineering organisms: the cellular interface ⬇️

scientific article published on November 1, 2003

CSL-independent Notch signalling: a checkpoint in cell fate decisions during development?

scientific article

Cell and molecular biology of Notch.

scientific article

Cell dynamics and gene expression control in tissue homeostasis and development.

scientific article published on January 2015

Cell signaling. Frizzled at the cutting edge of the synapse

scientific article published on 01 November 2005

Contractile and mechanical properties of epithelia with perturbed actomyosin dynamics

scientific article (publication date: 2014)

Correlations between the levels of Oct4 and Nanog as a signature for naïve pluripotency in mouse embryonic stem cells

scientific article published on December 2012

Debate ethics of embryo models from stem cells

scientific article published on 01 December 2018

Determining protein subcellular localization in mammalian cell culture with biochemical fractionation and iTRAQ 8-plex quantification

scientific article published on 01 January 2014

Dpp signalling orchestrates dorsal closure by regulating cell shape changes both in the amnioserosa and in the epidermis

scientific article published on 18 September 2007

Drosophila melanogaster and the development of biology in the 20th century

scientific article

Endocytic and recycling endosomes modulate cell shape changes and tissue behaviour during morphogenesis in Drosophila

scientific article

Evo-engineering and the cellular and molecular origins of the vertebrate spinal cord.

scientific article published on 9 February 2017

Experimental embryology of gastrulation: pluripotent stem cells as a new model system

scientific article published on 11 July 2020

FGF/MAPK signaling sets the switching threshold of a bistable circuit controlling cell fate decisions in embryonic stem cells

scientific article published on 28 October 2015

Flamingo regulates epiboly and convergence/extension movements through cell cohesive and signalling functions during zebrafish gastrulation

scientific article published on 17 December 2008

Gastruloids develop the three body axes in the absence of extraembryonic tissues and spatially localised signalling

Gene expression heterogeneities in embryonic stem cell populations: origin and function

scientific article

Generation of Aggregates of Mouse Embryonic Stem Cells that Show Symmetry Breaking, Polarization and Emergent Collective Behaviour In Vitro

scientific article

High-resolution crystal structure of the human Notch 1 ankyrin domain

scientific article

In vitro teratogenicity testing using a 3D, embryo-like gastruloid system

scientific article published on 20 August 2021

Inhibition of β-catenin-TCF1 interaction delays differentiation of mouse embryonic stem cells

scientific article

Interactions between Nodal and Wnt signalling Drive Robust Symmetry Breaking and Axial Organisation inGastruloids(Embryonic Organoids)

article published in 2016

Interactions between the amnioserosa and the epidermis revealed by the function of the u-shaped gene

scientific article published on 16 February 2012

Ligand-independent traffic of Notch buffers activated Armadillo in Drosophila

scientific article

Mapping organelle proteins and protein complexes in Drosophila melanogaster

scientific article

Mechanical control of global cell behaviour during dorsal closure in Drosophila

scientific article

Mechanisms of ligand-mediated inhibition in Notch signaling activity in Drosophila.

scientific article published in March 2010

Modulation of the ligand-independent traffic of Notch by Axin and Apc contributes to the activation of Armadillo in Drosophila.

scientific article

Multi-axial self-organization properties of mouse embryonic stem cells into gastruloids

scientific article published in Nature

Neuro-mesodermal progenitors (NMPs): a comparative study between pluripotent stem cells and embryo-derived populations

scientific article published on 24 June 2019

New alleles of Notch draw a blueprint for multifunctionality

scientific article published in April 2002

Notch modulates Wnt signalling by associating with Armadillo/beta-catenin and regulating its transcriptional activity

scientific article published on 16 March 2005

Notch receptor encodes two structurally separable functions in Drosophila: a genetic analysis.

scientific article published in April 2006

Notch synergizes with axin to regulate the activity of armadillo in Drosophila

scientific article published in October 2006

Notch, a universal arbiter of cell fate decisions

scientific article published on 01 December 2006

On the nature and function of organizers.

scientific article published on 9 March 2018

Organoids and the genetically encoded self-assembly of embryonic stem cells

scientific article

Origin and function of fluctuations in cell behaviour and the emergence of patterns.

scientific article published on 07 August 2009

Patterned Cell Adhesion Associated with Tissue Deformations during Dorsal Closure in Drosophila ⬇️

scientific article published on November 4, 2011

Planar polarity and actin dynamics in the epidermis of Drosophila

scientific article published in December 2002

Pluripotent stem cell models of early mammalian development

scientific article published on 06 July 2020

Publisher Correction: Single-cell and spatial transcriptomics reveal somitogenesis in gastruloids

scientific article published on 01 March 2020

Regulated fluctuations in nanog expression mediate cell fate decisions in embryonic stem cells

scientific article

Requirements for adherens junction components in the interaction between epithelial tissues during dorsal closure in Drosophila

scientific article published in September 2007

Reverse-engineering growth and form in Heidelberg

scientific article published on 19 July 2019

Single cell lineage analysis of mouse embryonic stem cells at the exit from pluripotency

scientific article published on 19 August 2013

Single-Cell Approaches: Pandora's Box of Developmental Mechanisms

scientific article published in September 2016

Single-cell and spatial transcriptomics reveal somitogenesis in gastruloids

scientific article published on 19 February 2020

Symmetry breaking, germ layer specification and axial organisation in aggregates of mouse embryonic stem cells

scientific article

The Drosophila STIM1 orthologue, dSTIM, has roles in cell fate specification and tissue patterning

scientific article

The hope and the hype of organoid research.

scientific article published on March 2017

The structure of Wntch signalling and the resolution of transition states in development.

scientific article published on 04 February 2012

Towards a statistical mechanics of cell fate decisions

scientific article

Transition states and cell fate decisions in epigenetic landscapes

scientific article published on 12 September 2016

What Is Your Conceptual Definition of "Cell Type" in the Context of a Mature Organism? ⬇️

scientific article published on 01 March 2017

Wingless modulates the ligand independent traffic of Notch through Dishevelled.

scientific article published in July 2010

Wnt/Notch signalling and information processing during development.

scientific article published on February 2008

Wnt/ß-catenin signalling and the dynamics of fate decisions in early mouse embryos and embryonic stem (ES) cells ⬇️

scientific article

Wnt/β-catenin and FGF signalling direct the specification and maintenance of a neuromesodermal axial progenitor in ensembles of mouse embryonic stem cells

scientific article

Wnts as morphogens? The view from the wing of Drosophila

scientific article

Wnt‐Notch signalling: An integrated mechanism regulating transitions between cell states ⬇️

scientific article published on January 3, 2012

List of works by Alfonso Martinez Arias

A Sprouty4 reporter to monitor FGF/ERK signaling activity in ESCs and mice

A competitive protein interaction network buffers Oct4-mediated differentiation to promote pluripotency in embryonic stem cells

A draft map of the mouse pluripotent stem cell spatial proteome

A membrane-associated β-catenin/Oct4 complex correlates with ground-state pluripotency in mouse embryonic stem cells

A molecular basis for developmental plasticity in early mammalian embryos

A new dawn for an old connection: development meets the cell

An epiblast stem cell-derived multipotent progenitor population for axial extension

An in vitro model of early anteroposterior organization during human development

An interplay between extracellular signalling and the dynamics of the exit from pluripotency drives cell fate decisions in mouse ES cells

Anteroposterior polarity and elongation in the absence of extra-embryonic tissues and of spatially localised signalling in gastruloids: mammalian embryonic organoids

Armadillo/beta-catenin-dependent Wnt signalling is required for the polarisation of epidermal cells during dorsal closure in Drosophila

Axis Specification in Zebrafish Is Robust to Cell Mixing and Reveals a Regulation of Pattern Formation by Morphogenesis

Axis Specification in Zebrafish Is Robust to Cell Mixing and Reveals a Regulation of Pattern Formation by Morphogenesis

Brachyury cooperates with Wnt/β-catenin signalling to elicit primitive-streak-like behaviour in differentiating mouse embryonic stem cells

Building and engineering organisms: the cellular interface ⬇️

CSL-independent Notch signalling: a checkpoint in cell fate decisions during development?

Cell and molecular biology of Notch.

Cell dynamics and gene expression control in tissue homeostasis and development.

Cell signaling. Frizzled at the cutting edge of the synapse

Contractile and mechanical properties of epithelia with perturbed actomyosin dynamics

Correlations between the levels of Oct4 and Nanog as a signature for naïve pluripotency in mouse embryonic stem cells

Debate ethics of embryo models from stem cells

Determining protein subcellular localization in mammalian cell culture with biochemical fractionation and iTRAQ 8-plex quantification

Dpp signalling orchestrates dorsal closure by regulating cell shape changes both in the amnioserosa and in the epidermis

Drosophila melanogaster and the development of biology in the 20th century

Endocytic and recycling endosomes modulate cell shape changes and tissue behaviour during morphogenesis in Drosophila

Evo-engineering and the cellular and molecular origins of the vertebrate spinal cord.

Experimental embryology of gastrulation: pluripotent stem cells as a new model system

FGF/MAPK signaling sets the switching threshold of a bistable circuit controlling cell fate decisions in embryonic stem cells

Flamingo regulates epiboly and convergence/extension movements through cell cohesive and signalling functions during zebrafish gastrulation

Gastruloids develop the three body axes in the absence of extraembryonic tissues and spatially localised signalling

Gene expression heterogeneities in embryonic stem cell populations: origin and function

Generation of Aggregates of Mouse Embryonic Stem Cells that Show Symmetry Breaking, Polarization and Emergent Collective Behaviour In Vitro

High-resolution crystal structure of the human Notch 1 ankyrin domain

In vitro teratogenicity testing using a 3D, embryo-like gastruloid system

Inhibition of β-catenin-TCF1 interaction delays differentiation of mouse embryonic stem cells

Interactions between Nodal and Wnt signalling Drive Robust Symmetry Breaking and Axial Organisation inGastruloids(Embryonic Organoids)

Interactions between the amnioserosa and the epidermis revealed by the function of the u-shaped gene

Ligand-independent traffic of Notch buffers activated Armadillo in Drosophila

Mapping organelle proteins and protein complexes in Drosophila melanogaster

Mechanical control of global cell behaviour during dorsal closure in Drosophila

Mechanisms of ligand-mediated inhibition in Notch signaling activity in Drosophila.

Modulation of the ligand-independent traffic of Notch by Axin and Apc contributes to the activation of Armadillo in Drosophila.

Multi-axial self-organization properties of mouse embryonic stem cells into gastruloids

Neuro-mesodermal progenitors (NMPs): a comparative study between pluripotent stem cells and embryo-derived populations

New alleles of Notch draw a blueprint for multifunctionality

Notch modulates Wnt signalling by associating with Armadillo/beta-catenin and regulating its transcriptional activity

Notch receptor encodes two structurally separable functions in Drosophila: a genetic analysis.

Notch synergizes with axin to regulate the activity of armadillo in Drosophila

Notch, a universal arbiter of cell fate decisions

On the nature and function of organizers.

Organoids and the genetically encoded self-assembly of embryonic stem cells

Origin and function of fluctuations in cell behaviour and the emergence of patterns.

Patterned Cell Adhesion Associated with Tissue Deformations during Dorsal Closure in Drosophila ⬇️

Planar polarity and actin dynamics in the epidermis of Drosophila

Pluripotent stem cell models of early mammalian development

Publisher Correction: Single-cell and spatial transcriptomics reveal somitogenesis in gastruloids

Regulated fluctuations in nanog expression mediate cell fate decisions in embryonic stem cells

Requirements for adherens junction components in the interaction between epithelial tissues during dorsal closure in Drosophila

Reverse-engineering growth and form in Heidelberg

Single cell lineage analysis of mouse embryonic stem cells at the exit from pluripotency

Single-Cell Approaches: Pandora's Box of Developmental Mechanisms

Single-cell and spatial transcriptomics reveal somitogenesis in gastruloids

Symmetry breaking, germ layer specification and axial organisation in aggregates of mouse embryonic stem cells

The Drosophila STIM1 orthologue, dSTIM, has roles in cell fate specification and tissue patterning

The hope and the hype of organoid research.

The structure of Wntch signalling and the resolution of transition states in development.

Towards a statistical mechanics of cell fate decisions

Transition states and cell fate decisions in epigenetic landscapes

What Is Your Conceptual Definition of "Cell Type" in the Context of a Mature Organism? ⬇️

Wingless modulates the ligand independent traffic of Notch through Dishevelled.

Wnt/Notch signalling and information processing during development.

Wnt/ß-catenin signalling and the dynamics of fate decisions in early mouse embryos and embryonic stem (ES) cells ⬇️

Wnt/β-catenin and FGF signalling direct the specification and maintenance of a neuromesodermal axial progenitor in ensembles of mouse embryonic stem cells

Wnts as morphogens? The view from the wing of Drosophila

Wnt‐Notch signalling: An integrated mechanism regulating transitions between cell states ⬇️