Search filters

List of works by Richard Mains

5 Peptidylglycine α-amidating monooxygenase: An ascorbate-requiring enzyme

scientific article published on January 1, 1997

60 YEARS OF POMC: From POMC and α-MSH to PAM, molecular oxygen, copper, and vitamin C

scientific article

A Neuroendocrine-specific Protein Localized to the Endoplasmic Reticulum by Distal Degradation ⬇️

scientific article published on November 3, 1995

A Novel Neuroendocrine Intracellular Signaling Pathway ⬇️

scientific article published on November 1, 1997

A PAL for Schistosoma mansoni PHM.

scientific article

A Role for Kalirin in the Response of Rat Medium Spiny Neurons to Cocaine ⬇️

scientific article published on July 24, 2012

A bioactive peptide amidating enzyme is required for ciliogenesis

scientific article

A functionally atypical amidating enzyme from the human parasite Schistosoma mansoni

article published in 2004

A histidine-rich linker region in peptidylglycine α-amidating monooxygenase has the properties of a pH sensor

scientific article

A molluscan peptide alpha-amidating enzyme precursor that generates five distinct enzymes.

scientific article published in April 1999

A pH-sensitive luminal His-cluster promotes interaction of PAM with V-ATPase along the secretory and endocytic pathways of peptidergic cells

article

A role for Kalirin-7 in nociceptive sensitization via activity-dependent modulation of spinal synapses

scientific journal article

A signal sequence is sufficient for green fluorescent protein to be routed to regulated secretory granules

scientific article

AP-1A controls secretory granule biogenesis and trafficking of membrane secretory granule proteins

scientific article

ATP7A (Menkes protein) functions in axonal targeting and synaptogenesis

scientific article published on 9 January 2007

Ability of cofactors to support peptide amidation is cell-type specific

scientific article published in January 1989

Access of a membrane protein to secretory granules is facilitated by phosphorylation

scientific article published on 27 August 2001

Activation and routing of membrane-tethered prohormone convertases 1 and 2.

scientific article published on August 1999

Adaptor Protein-1 Complex Affects the Endocytic Trafficking and Function of Peptidylglycine α-Amidating Monooxygenase, a Luminal Cuproenzyme

scientific journal article

Adrenocorticotropin(1-14)OH-related molecules in primary cultures of rat intermediate pituitary cells. Identification and role in the biosynthesis of alpha-melanotropin ⬇️

scientific article published on June 25, 1983

Altered ATP7A expression and other compensatory responses in a murine model of Menkes disease

scientific article

Alternate promoter usage generates two subpopulations of the neuronal RhoGEF Kalirin-7.

scientific article published on 28 July 2016

Alternative splicing and endoproteolytic processing generate tissue-specific forms of pituitary peptidylglycine alpha-amidating monooxygenase (PAM) ⬇️

scientific article published on February 25, 1992

Amidation of Bioactive Peptides: The Structure of the Lyase Domain of the Amidating Enzyme

scientific article

Amidation of bioactive peptides: the structure of peptidylglycine alpha-hydroxylating monooxygenase

scientific article

Amidation of joining peptide, a major pro-ACTH/endorphin-derived product peptide

scientific article published in July 1986

An N-terminal Amphipathic Helix Binds Phosphoinositides and Enhances Kalirin Sec14 Domain-mediated Membrane Interactions

scientific article published on 10 April 2015

An isoform of kalirin, a brain-specific GDP/GTP exchange factor, is enriched in the postsynaptic density fraction

scientific article published on 01 March 2000

Analysis of kalirin-7 knockout mice reveals different effects in female mice

scientific article

Analysis of the common precursor to corticotropin and endorphin ⬇️

scientific article published on August 25, 1978

Autonomous functions for the Sec14p/spectrin-repeat region of Kalirin

scientific article published on 29 May 2008

Behavioral and morphological responses to cocaine require kalirin7.

scientific article

Biochemical characterization of peptide alpha-amidation enzyme activities of human neuroendocrine lung cancer cell lines

scientific article published on 01 November 1993

Biosynthesis of adrenocorticotropic hormone in mouse pituitary tumor cells ⬇️

scientific article published on July 10, 1976

Biosynthesis of amidated joining peptide from pro-adrenocorticotropin-endorphin

scientific article published on 01 September 1987

Biosynthetic studies on ACTH, beta-endorphin, and alpha-melanotropin in the rat ⬇️

scientific article published on January 1, 1980

Bovine intermediate pituitary alpha-amidation enzyme: preliminary characterization

scientific article published in November 1983

Brain Region and Isoform-Specific Phosphorylation Alters Kalirin SH2 Domain Interaction Sites and Calpain Sensitivity.

scientific article

Breeding stock-specific variation in peptidylglycine alpha-amidating monooxygenase messenger ribonucleic acid splicing in rat pituitary

scientific article published on 01 February 2000

COOH-terminal signals mediate the trafficking of a peptide processing enzyme in endocrine cells

scientific article

Calcitionin is not contained within the common precursor to corticotropin and endorphin in the rat ⬇️

scientific article published on July 27, 1979

Cdk5 and Trio modulate endocrine cell exocytosis

scientific journal article

Cell type-specific metabolism of peptidylglycine alpha-amidating monooxygenase in anterior pituitary

scientific article

Cell-type specific knockout of peptidylglycine α-amidating monooxygenase reveals specific behavioral roles in excitatory forebrain neurons and cardiomyocytes

scientific article published on 09 September 2020

Cerulein mRNA and peptide alpha-amidation activity in the skin of Xenopus laevis: stimulation by norepinephrine

scientific article published on 01 July 1987

Changes in Corticotrope Gene Expression Upon Increased Expression of Peptidylglycine α-Amidating Monooxygenase

scientific article published on 01 July 2018

Characterization of a peptide alpha-amidation activity from rat anterior pituitary.

scientific article published in May 1984

Characterization of mouse tumor cell beta-lipotropin ⬇️

scientific article published on October 25, 1979

Characterization of peptide alpha-amidation activity in human cerebrospinal fluid and central nervous system tissue

Cilia-based peptidergic signaling

scientific article published on 06 December 2019

Ciliary and cytoskeletal functions of an ancient monooxygenase essential for bioactive amidated peptide synthesis

scientific article published on 16 March 2019

Common precursor to corticotropins and endorphins ⬇️

scientific article published on July 1, 1977

Comparison of Rat Anterior and Intermediate Pituitary in Tissue Culture: Corticotropin (ACTH) and β‐Endorphin ⬇️

scientific article published on 01 January 1981

Constitutive knockout of kalirin-7 leads to increased rates of cocaine self-administration

scientific article

Coordinate synthesis of corticotropins and endorphins by mouse pituitary tumor cells ⬇️

scientific article published on February 10, 1978

Coordinate, equimolar secretion of smaller peptide products derived from pro-ACTH/endorphin by mouse pituitary tumor cells

scientific article

Coordination of peroxide to the CuM center of peptidylglycine α-hydroxylating monooxygenase (PHM): structural and computational study

scientific article

Copper signaling in the mammalian nervous system: synaptic effects

scientific article

Copper, zinc and calcium: imaging and quantification in anterior pituitary secretory granules

scientific article published on 18 July 2016

Correction to: PAM haploinsufficiency does not accelerate the development of diet and human IAPP-induced diabetes in mice

scientific article published on 01 May 2020

Deletion of peptide amidation enzymatic activity leads to edema and embryonic lethality in the mouse

scientific article

Developmental changes in the expression of ATP7A during a critical period in postnatal neurodevelopment

scientific article published on 23 March 2006

Differences in the post-translational processing of beta-endorphin in rat anterior and intermediate pituitary ⬇️

scientific article published on June 10, 1981

Differences in the ways sympathetic neurons and endocrine cells process, store, and secrete exogenous neuropeptides and peptide-processing enzymes.

scientific article published on October 1999

Differential Reactivity between Two Copper Sites in Peptidylglycine α-Hydroxylating Monooxygenase

scientific article

Differential effects of temperature blockade on the proteolytic processing of three secretory granule-associated proteins

scientific article published on 01 March 1994

Differential trafficking of soluble and integral membrane secretory granule-associated proteins

scientific article

Dioxygen binds end-on to mononuclear copper in a precatalytic enzyme complex

scientific article

Distinct roles for the two Rho GDP/GTP exchange factor domains of kalirin in regulation of neurite growth and neuronal morphology.

scientific article published on November 2001

Dopaminergic regulation of secretory granule-associated proteins in rat intermediate pituitary

scientific article published on 01 July 1996

Drosophila uses two distinct neuropeptide amidating enzymes, dPAL1 and dPAL2.

scientific article published on July 2004

Dynamics of peptidergic secretory granule transport are regulated by neuronal stimulation

scientific journal article

Early eukaryotic origins for cilia-associated bioactive peptide-amidating activity.

scientific article

Effects of cocaine and withdrawal on the mouse nucleus accumbens transcriptome.

scientific article published on 27 November 2012

Effects of copper occupancy on the conformational landscape of peptidylglycine α-hydroxylating monooxygenase

Elimination of Kalrn expression in POMC cells reduces anxiety-like behavior and contextual fear learning

scientific article

Endoproteolytic processing of proopiomelanocortin and prohormone convertases 1 and 2 in neuroendocrine cells overexpressing prohormone convertases 1 or 2.

scientific article published on July 1994

Enzymatic activity of soluble and membrane tethered peptide pro-hormone convertase 1.

scientific article published in May 2002

Essential features of the catalytic core of peptidyl-alpha-hydroxyglycine alpha-amidating lyase

scientific article published in October 2002

Evidence for a peptide similar to 16K fragment in man. Its relationship to ACTH ⬇️

scientific article published on 01 July 1980

Existence of a common precursor to ACTH and endorphin in the anterior and intermediate lobes of the rat pituaitary ⬇️

scientific article published on January 1, 1978

Expression of RESP18 in Peptidergic and Catecholaminergic Neurons ⬇️

scientific article published on September 1, 1997

Expression of Trio, a member of the Dbl family of Rho GEFs in the developing rat brain

scientific article published in February 2005

Expression of a peptide processing enzyme in cultured cells: truncation mutants reveal a routing domain

scientific article published on December 1, 1992

Expression of individual forms of peptidylglycine alpha-amidating monooxygenase in AtT-20 cells: endoproteolytic processing and routing to secretory granules ⬇️

scientific article published on May 1, 1992

Expression of kalirin, a neuronal GDP/GTP exchange factor of the trio family, in the central nervous system of the adult rat.

scientific article

Expression of prohormone processing enzymes in neuroendocrine and non-neuroendocrine cells

scientific article published on January 1, 1992

Flow cytometry-assisted purification and proteomic analysis of the corticotropes dense-core secretory granules

scientific article

Fluoride causes reversible dispersal of Golgi cisternae and matrix in neuroendocrine cells

scientific article published on 01 August 2004

Further analysis of post-translational processing of beta-endorphin in rat intermediate pituitary ⬇️

scientific article published on June 10, 1981

Genetic determinants of amidating enzyme activity and its relationship with metal cofactors in human serum

scientific article

Genomic organization and differential expression of Kalirin isoforms

scientific article

Global Approaches to the Role of miRNAs in Drug-Induced Changes in Gene Expression ⬇️

scientific article published on June 13, 2012

Haploinsufficiency in peptidylglycine alpha-amidating monooxygenase leads to altered synaptic transmission in the amygdala and impaired emotional responses

scientific article

High levels of expression of the tumor suppressor gene APC during development of the rat central nervous system.

scientific article published in May 1994

High molecular weight forms of adrenocorticotropic hormone are glycoproteins ⬇️

scientific article published on July 10, 1976

High molecular weight forms of adrenocorticotropic hormone in the mouse pituitary and in a mouse pituitary tumor cell line ⬇️

scientific article published on August 26, 1975

High serum Cu and Cu/Zn ratios correlate with impairments in bone density, physical performance and overall health in a population of elderly men with frailty characteristics

scientific article published on 29 March 2012

Hormonal, drug, and dietary factors affecting peptidyl glycine alpha-amidating monooxygenase activity in various tissues of the adult male rat.

scientific article published in June 1985

Identification in pituitary tissue of a peptide alpha-amidation activity that acts on glycine-extended peptides and requires molecular oxygen, copper, and ascorbic acid

scientific article published on August 1983

Identification of kalirin-7 as a potential post-synaptic density signaling hub

scientific article

Identification of routing determinants in the cytosolic domain of a secretory granule-associated integral membrane protein

scientific journal article

Identification of the promoter for the gene encoding the bifunctional enzyme, peptidylglycine alpha-amidating monooxygenase

scientific article published on December 1996

Identifying roles for peptidergic signaling in mice

scientific article published on 27 August 2019

In vivo and in vitro analyses of amygdalar function reveal a role for copper

scientific article

Inducible genetic suppression of neuronal excitability

scientific article published on 01 March 1999

Induction of integral membrane PAM expression in AtT-20 cells alters the storage and trafficking of POMC and PC1.

scientific article

Induction of lamellipodia by Kalirin does not require its guanine nucleotide exchange factor activity

scientific article published on 21 April 2005

Inhibition of peptide amidation by disulfiram and diethyldithiocarbamate.

scientific article

Inhibitors of the V0 subunit of the vacuolar H+-ATPase prevent segregation of lysosomal- and secretory-pathway proteins

scientific article

Interactions of peptide amidation and copper: novel biomarkers and mechanisms of neural dysfunction

scientific article published on 06 October 2009

Investigation of the Structural Requirements for Peptide Precursor Processing in AtT-20 Cells Using Site-Directed Mutagenesis of Proadrenocorticotropin/Endorphin ⬇️

scientific article published on March 1, 1991

Isoforms of kalirin, a neuronal Dbl family member, generated through use of different 5'- and 3'-ends along with an internal translational initiation site

scientific journal article

Kalirin Dbl-homology guanine nucleotide exchange factor 1 domain initiates new axon outgrowths via RhoG-mediated mechanisms

scientific journal article

Kalirin binds the NR2B subunit of the NMDA receptor, altering its synaptic localization and function

scientific journal article

Kalirin expression is regulated by multiple promoters

scientific article published on January 2004

Kalirin inhibition of inducible nitric-oxide synthase

scientific article

Kalirin is required for BDNF-TrkB stimulated neurite outgrowth and branching

scientific article published on 29 March 2016

Kalirin promotes neointimal hyperplasia by activating Rac in smooth muscle cells

scientific journal article

Kalirin, a cytosolic protein with spectrin-like and GDP/GTP exchange factor-like domains that interacts with peptidylglycine alpha-amidating monooxygenase, an integral membrane peptide-processing enzyme

scientific article published in May 1997

Kalirin, a multifunctional PAM COOH-terminal domain interactor protein, affects cytoskeletal organization and ACTH secretion from AtT-20 cells

scientific article

Kalirin, a multifunctional Rho guanine nucleotide exchange factor, is necessary for maintenance of hippocampal pyramidal neuron dendrites and dendritic spines

scientific journal article

Kalirin-7 is an essential component of both shaft and spine excitatory synapses in hippocampal interneurons

scientific article published on January 2008

Kalirin-7 is necessary for normal NMDA receptor-dependent synaptic plasticity

scientific article

Kalirin-7 is required for synaptic structure and function

scientific article

Kalirin-7, an important component of excitatory synapses, is regulated by estradiol in hippocampal neurons

scientific article

Kalirin-9 and Kalirin-12 Play Essential Roles in Dendritic Outgrowth and Branching

scientific article

Kalirin/Trio Rho GDP/GTP exchange factors regulate proinsulin and insulin secretion

scientific article published on 01 November 2018

Kalirin/Trio Rho guanine nucleotide exchange factors regulate a novel step in secretory granule maturation

scientific article

Kalirin12 interacts with dynamin

scientific article

Kalirin: a dual Rho guanine nucleotide exchange factor that is so much more than the sum of its many parts

scientific article

Kalrn plays key roles within and outside of the nervous system

scientific article

Kalrn promoter usage and isoform expression respond to chronic cocaine exposure

scientific article

Localization of integral membrane peptidylglycine alpha-amidating monooxygenase in neuroendocrine cells

scientific article published on March 1997

Localization of the gene encoding peptidylglycine alpha-amidating monooxygenase (PAM) to human chromosome 5q14-5q21

scientific article

Location of neurons that express regulated endocrine-specific protein-18 in the rat diencephalon

scientific article

Manipulation of Neuropeptide Biosynthesis through the Expression of Antisense RNA for Peptidylglycine α-Amidating Monooxygenase ⬇️

scientific article published on February 1, 1991

Mechanistic investigation of peptidylglycine alpha-hydroxylating monooxygenase via intrinsic tryptophan fluorescence and mutagenesis

scientific article published on June 2003

Menkes protein contributes to the function of peptidylglycine alpha-amidating monooxygenase

scientific journal article

Microvillar and ciliary defects in zebrafish lacking an actin-binding bioactive peptide amidating enzyme.

scientific article

Molecular weights of adrenocorticotropic hormone in extracts of anterior and intermediate-posterior lobes of mouse pituitary ⬇️

scientific article published on September 1, 1975

Monooxygenase X, a member of the copper-dependent monooxygenase family localized to the endoplasmic reticulum

scientific article

Multiple novel isoforms of Trio are expressed in the developing rat brain

scientific article

Neurodevelopmental disease-associated de novo mutations and rare sequence variants affect TRIO GDP/GTP exchange factor activity

scientific article published on 14 September 2017

Neuronal Rho GEFs in synaptic physiology and behavior

scientific article published on 11 February 2013

Neuronal growth cone retraction relies on proneurotrophin receptor signaling through Rac.

scientific article

Neuropeptide amidation in Drosophila: separate genes encode the two enzymes catalyzing amidation.

scientific article published in February 1997

New insights into copper monooxygenases and peptide amidation: structure, mechanism and function

scientific article (publication date: August 2000)

Nonenzymatic domains of Kalirin7 contribute to spine morphogenesis through interactions with phosphoinositides and Abl

scientific article published on 05 March 2014

Not all secretory granules are created equal: Partitioning of soluble content proteins.

scientific article published on 27 September 2006

Novel proteins that interact with the COOH-terminal cytosolic routing determinants of an integral membrane peptide-processing enzyme

scientific journal article

O-Glycosylation of a Secretory Granule Membrane Enzyme Is Essential for Its Endocytic Trafficking

scientific article published on 9 March 2016

Optimizing production of Fc-amidated peptides by Chinese hamster ovary cells

scientific article published on 16 October 2015

PACE4: a subtilisin-like endoprotease prevalent in the anterior pituitary and regulated by thyroid status

scientific journal article

PAM haploinsufficiency does not accelerate the development of diet- and human IAPP-induced diabetes in mice

scientific article published on 27 January 2020

PHM is required for normal developmental transitions and for biosynthesis of secretory peptides in Drosophila

scientific article published on October 2000

Pam heterozygous mice reveal essential role for Cu in amygdalar behavioral and synaptic function

scientific article

Partial characterization of a glycoprotein comprising the NH2-terminal region of mouse tumor cell pro-adrenocorticotropic hormone/endorphin ⬇️

scientific article published on September 25, 1979

Peptide alpha-amidation

scientific article published on January 1988

Peptide alpha-amidation activity in mouse anterior pituitary AtT-20 cell granules: properties and secretion

scientific article published in May 1984

Peptide alpha-amidation and peptidylglycine alpha-hydroxylating monooxygenase: control by disulfiram

scientific article published on November 1993

Peptide analysis of a glycoprotein form of adrenocorticotropic hormone ⬇️

scientific article published on December 25, 1977

Peptidyl-alpha-hydroxyglycine alpha-amidating lyase. Purification, characterization, and expression

scientific article

Peptidyl-glycine alpha-amidation activity in tissues and serum of the adult rat.

scientific article published in June 1985

Peptidylglycine alpha-amidating monooxygenase and other processing enzymes in the neurointermediate pituitary

scientific article

Peptidylglycine alpha-amidating monooxygenase: a multifunctional protein with catalytic, processing, and routing domains

scientific article

Peptidylglycine α-Hydroxylating Monooxygenase: Active Site Residues, Disulfide Linkages, and a Two-Domain Model of the Catalytic Core ⬇️

scientific article published on 01 September 1997

Peptidylglycine α-amidating monooxygenase heterozygosity alters brain copper handling with region specificity

scientific article published on 13 October 2013

Peptidylglycine α-amidating monooxygenase is required for atrial secretory granule formation

scientific article published on 13 July 2020

Peptidylgycine α-amidating monooxygenase and copper: a gene-nutrient interaction critical to nervous system function

scientific article published on September 2010

Phosphorylation of Rat and Human Adrenocorticotropin Related Peptides: Physiological Regulation and Studies of Secretion ⬇️

scientific article published on June 1, 1983

Phosphorylation of cytosolic domain Ser(937) affects both biosynthetic and endocytic trafficking of peptidylglycine alpha-amidating monooxygenase

scientific article published on July 1999

Phosphorylation of pro-adrenocorticotropin/endorphin-derived peptides.

scientific article published in May 1982

Plasticity in hippocampal peptidergic systems induced by repeated electroconvulsive shock

scientific article

Post-translational N-Glycosylation of a Truncated Form of a Peptide Processing Enzyme ⬇️

scientific article published on September 4, 1998

Post-translational processing of neuropeptide precursors

scientific article published on January 1, 1984

Posttranslational processing of transfected mouse pro-adrenocorticotropin/endorphin in rat growth hormone-secreting tumor cells

scientific article published on 01 October 1989

Primary sequence of two regions of mouse proadrenocorticotropin/proendorphin ⬇️

scientific article published on 01 July 1981

Probing the production of amidated peptides following genetic and dietary copper manipulations

scientific article

Processing and routing of a membrane-anchored form of proneuropeptide Y

scientific article published on 01 July 1996

Prohormone-converting enzymes: regulation and evaluation of function using antisense RNA.

scientific article

Proteases Shape the Chlamydomonas Secretome: Comparison to Classical Neuropeptide Processing Machinery

scientific article published on 23 September 2018

Purification and characterization of peptidylglycine alpha-amidating monooxygenase from bovine neurointermediate pituitary

scientific article

Quantitative peptidomics of pituitary glands from mice deficient in copper transport

scientific article published on July 1, 2003

RESP18, a novel endocrine secretory protein transcript, and four other transcripts are regulated in parallel with pro-opiomelanocortin in melanotropes

scientific journal article

Rapid increases in peptide processing enzyme expression in hippocampal neurons

scientific article published on 01 October 1993

Rapid induction of dendritic spine morphogenesis by trans-synaptic ephrinB-EphB receptor activation of the Rho-GEF kalirin

scientific journal article

Recombinant DNA to study neuropeptide processing. General introduction

scientific article published on 01 January 1988

Regulated endocrine-specific protein-18: a short-lived novel glucocorticoid-regulated endocrine protein

scientific journal article

Regulation of Kalirin by Cdk5

scientific article (publication date: August 2008)

Response of an integral granule membrane protein to changes in pH

scientific journal article

Retrieval and reuse of pituitary secretory granule proteins

scientific journal article

Reversal of physiological deficits caused by diminished levels of peptidylglycine alpha-amidating monooxygenase by dietary copper

scientific article

Role for an essential tyrosine in peptide amidation

scientific article published on 16 May 2006

Role of Kalirin and mouse strain in retention of spatial memory training in an Alzheimer's disease model mouse line

scientific article published on 14 July 2020

Role of adaptor proteins in secretory granule biogenesis and maturation

scientific article published on 14 August 2013

Routing of membrane proteins to large dense core vesicles in PC12 cells

scientific article

Secretion Stimulates Intramembrane Proteolysis of a Secretory Granule Membrane Enzyme ⬇️

scientific article published on September 3, 2010

Secretion and Regulation of Two Biosynthetic Enzyme Activities, Peptidyl-Glycineα-Amidating Monooxygenase and a Carboxypeptidase, by Mouse Pituitary Corticotropic Tumor Cells* ⬇️

scientific article published on 01 November 1984

Secretion of Fc-amidated peptide fusion proteins by Chinese hamster ovary cells

scientific article published on 27 June 2015

Secretory granule membrane protein recycles through multivesicular bodies

scientific article

Secretory granule to the nucleus: role of a multiply phosphorylated intrinsically unstructured domain

scientific article published on 27 July 2009

Selective loss of alpha-melanotropin-amidating activity in primary cultures of rat intermediate pituitary cells ⬇️

scientific article published on June 25, 1983

Sex-Specific Gene Expression in the Mouse Nucleus Accumbens Before and After Cocaine Exposure

article

Signaling from the secretory granule to the nucleus ⬇️

scientific article published on 08 June 2012

Signaling from the secretory granule to the nucleus: Uhmk1 and PAM

scientific article

Signaling mediated by the cytosolic domain of peptidylglycine alpha-amidating monooxygenase

scientific journal article

Stable expression of full-length and truncated bovine peptidylglycine alpha-amidating monooxygenase complementary DNAs in cultured cells

scientific article published on January 1990

Structural Elements That Direct Specific Processing of Different Mammalian Subtilisin-like Prohormone Convertases ⬇️

scientific article published on September 15, 1995

Structural Organization of the Nine Spectrin Repeats of Kalirin ⬇️

scientific article published on July 6, 2012

Structure and Biosynthesis of Pro-Adrenocorticotropin/Endorphin and Related Peptides* ⬇️

scientific article published on January 1, 1980

Structure of the precursor to an enzyme mediating COOH-terminal amidation in peptide biosynthesis

scientific article

Structure, distribution, and functional expression of the phosphofructokinase C isozyme

scientific journal article

Studies of peptide hormone biosynthesis and structure: ACTH, endorphin, and related molecules

scientific article published on January 1, 1979

Substrate-mediated electron transfer in peptidylglycine alpha-hydroxylating monooxygenase

scientific article

Supplying copper to the cuproenzyme peptidylglycine alpha-amidating monooxygenase

scientific journal article

Synaptic plasticity, a symphony in GEF.

scientific article published on May 2010

Synthesis and secretion of ACTH, beta-endorphin, and related peptides.

scientific article published on January 1981

Synthesis and secretion of corticotropins, melanotropins, and endorphins by rat intermediate pituitary cells ⬇️

scientific article published on August 25, 1979

Targeting of membrane proteins to the regulated secretory pathway in anterior pituitary endocrine cells

scientific article published in 2001

The NH2-terminal proregion of peptidylglycine alpha-amidating monooxygenase facilitates the secretion of soluble proteins

scientific article

The Ordered Secretion of Bioactive Peptides: Oldest or Newest First? ⬇️

scientific article published on June 1, 1991

The Rho-GEF Kalirin regulates bone mass and the function of osteoblasts and osteoclasts

scientific article published on 28 December 2013

The biosynthesis of neuropeptides: peptide alpha-amidation

scientific article published on January 1, 1992

The catalytic copper of peptidylglycine alpha-hydroxylating monooxygenase also plays a critical structural role

scientific article

The catalytic core of peptidylglycine alpha-hydroxylating monooxygenase: investigation by site-directed mutagenesis, Cu X-ray absorption spectroscopy, and electron paramagnetic resonance

scientific article published on March 1995

The catalytic role of the copper ligand H172 of peptidylglycine alpha-hydroxylating monooxygenase (PHM): a spectroscopic study of the H172A mutant

scientific article published in November 2002

The endocytic pathways of a secretory granule membrane protein in HEK293 cells: PAM and EGF traverse a dynamic multivesicular body network together.

scientific article published on 28 March 2017

The expression of regulated endocrine-specific protein of 18 kDa in peptidergic cells of rat peripheral endocrine tissues and in blood ⬇️

scientific article published on November 1, 1997

The multifunctional peptidylglycine alpha-amidating monooxygenase gene: exon/intron organization of catalytic, processing, and routing domains

scientific article (publication date: October 1992)

The neuronal Rho-GEF Kalirin-7 interacts with PDZ domain-containing proteins and regulates dendritic morphogenesis

scientific journal article

The novel kinase peptidylglycine alpha-amidating monooxygenase cytosolic interactor protein 2 interacts with the cytosolic routing determinants of the peptide processing enzyme peptidylglycine alpha-amidating monooxygenase

scientific article

The prohormone convertases PC1 and PC2 mediate distinct endoproteolytic cleavages in a strict temporal order during proopiomelanocortin biosynthetic processing.

scientific article published on January 1993

The role of ascorbate in the biosynthesis of neuroendocrine peptides

scientific article published on December 1991

The role of secretory granules in peptide biosynthesis

scientific article published in January 1987

The tissue-specific processing of Pro-ACTH/Endorphin recent advances and unsolved problems

scientific article published on 01 November 1990

Tissue culture of primary rat anterior pituitary cells

scientific article published on January 1, 1982

Topological Switching of the COOH-Terminal Domain of Peptidylglycine α-Amidating Monooxygenase by Alternative RNA Splicing ⬇️

scientific article (publication date: 15 February 1993)

Trafficking of a secretory granule membrane protein is sensitive to copper

scientific article

Transcriptional Profiling of Non-injured Nociceptors After Spinal Cord Injury Reveals Diverse Molecular Changes

scientific article published on 26 November 2019

Using Kalirin conditional knockout mice to distinguish its role in dopamine receptor mediated behaviors

scientific article

microRNA-Seq reveals cocaine-regulated expression of striatal microRNAs

scientific article

pH-dependent stimulation of peptidylglycine alpha-amidating monooxygenase activity by a granule-associated factor

scientific article published on December 1990

Paulina is supported by:

About Paulina

Help