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List of works by Fyodor Urnov

A TALE nuclease architecture for efficient genome editing

scientific article

A feel for the template: zinc finger protein transcription factors and chromatin

scientific article

Allele-selective transcriptional repression of mutant HTT for the treatment of Huntington's disease

scientific article published on 01 July 2019

Biotechnologies and therapeutics: chromatin as a target.

scientific article

Chromatin as a Tool for the Study of Genome Function in Cancer ⬇️

scientific article published on March 1, 2003

Chromatin remodeling as a guide to transcriptional regulatory networks in mammals

scientific article

Chromosomal translocations induced at specified loci in human stem cells.

scholarly article

Designed transcription factors as structural, functional and therapeutic probes of chromatin in vivo. Fourth in review series on chromatin dynamics

scientific article

Designed transcription factors as tools for therapeutics and functional genomics

scientific article

Distinct factors control histone variant H3.3 localization at specific genomic regions

scientific article

Don’t edit the human germ line

scientific article

Drug resistance. K13-propeller mutations confer artemisinin resistance in Plasmodium falciparum clinical isolates

scientific article

Efficient targeted gene disruption in the soma and germ line of the frog Xenopus tropicalis using engineered zinc-finger nucleases. ⬇️

scientific article

Efficient targeting of expressed and silent genes in human ESCs and iPSCs using zinc-finger nucleases

scientific article (publication date: September 2009)

Enhancing zinc-finger-nuclease activity with improved obligate heterodimeric architectures

scientific article

Establishment of HIV-1 resistance in CD4+ T cells by genome editing using zinc-finger nucleases

scientific article (publication date: July 2008)

Functional footprinting of regulatory DNA.

scientific article published on 31 August 2015

Functional genomics, proteomics, and regulatory DNA analysis in isogenic settings using zinc finger nuclease-driven transgenesis into a safe harbor locus in the human genome

scientific article

Gene editing in human stem cells using zinc finger nucleases and integrase-defective lentiviral vector delivery

scientific article (publication date: 28 October 2007)

Generation of isogenic pluripotent stem cells differing exclusively at two early onset Parkinson point mutations

scientific article published on 14 July 2011

Genetic and molecular identification of three human TPP1 functions in telomerase action: recruitment, activation, and homeostasis set point regulation

scientific article (publication date: September 2014)

Genetic engineering of human pluripotent cells using TALE nucleases

scientific article (publication date: 7 July 2011)

Genome editing of human embryonic stem cells and induced pluripotent stem cells with zinc finger nucleases for cellular imaging.

scientific article

Genome editing of isogenic human induced pluripotent stem cells recapitulates long QT phenotype for drug testing

scientific article

Genome editing with engineered zinc finger nucleases

scientific article

Heritable targeted gene disruption in zebrafish using designed zinc-finger nucleases

scientific article

Highly efficient endogenous human gene correction using designed zinc-finger nucleases

scientific article (publication date: 2 June 2005)

Human genome editing as a tool to establish causality

scientific article published on 15 January 2014

Human intestinal tissue with adult stem cell properties derived from pluripotent stem cells

scientific article

Identification of chromosome sequence motifs that mediate meiotic pairing and synapsis in C. elegans

scientific article published on 20 July 2009

Improved specificity of TALE-based genome editing using an expanded RVD repertoire

scientific article published on 23 March 2015

In vivo cleavage of transgene donors promotes nuclease-mediated targeted integration

scientific article

Isolation and characterization of the ecdysone receptor and its heterodimeric partner ultraspiracle through development in Sciara coprophila

scientific article published on 16 January 2013

Knockout rats via embryo microinjection of zinc-finger nucleases

scientific article

LRRK2 mutations cause mitochondrial DNA damage in iPSC-derived neural cells from Parkinson's disease patients: reversal by gene correction

scientific article published on 19 October 2013

Long-Term Engraftment and Fetal Globin Induction upon BCL11A Gene Editing in Bone-Marrow-Derived CD34+ Hematopoietic Stem and Progenitor Cells

scientific article published on 11 January 2017

Mammalian interspecies substitution of immune modulatory alleles by genome editing

scientific article published on 22 February 2016

Methylation and the genome: the power of a small amendment

scientific article

Precise genome modification in the crop species Zea mays using zinc-finger nucleases

scientific article (publication date: 21 May 2009)

Prime Time for Genome Editing?

scientific article published on 01 January 2020

Rapid and efficient clathrin-mediated endocytosis revealed in genome-edited mammalian cells ⬇️

scientific article published on February 6, 2011

Repression of vascular endothelial growth factor A in glioblastoma cells using engineered zinc finger transcription factors

scientific article (publication date: 15 December 2003)

Site-specific genome editing in Plasmodium falciparum using engineered zinc-finger nucleases

scientific article published on 26 August 2012

Targeted gene addition in human CD34(+) hematopoietic cells for correction of X-linked chronic granulomatous disease

scientific article published on 7 March 2016

Targeted gene addition into a specified location in the human genome using designed zinc finger nucleases

scholarly article

Targeted gene knockout in mammalian cells by using engineered zinc-finger nucleases.

scholarly article

Targeted genome editing across species using ZFNs and TALENs

scientific article

Targeted transgene integration in plant cells using designed zinc finger nucleases

scientific article

Translating dosage compensation to trisomy 21

scientific article

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