List of works - Michele T Pato

A comprehensive family-based replication study of schizophrenia genes

scientific article

A contribution of novel CNVs to schizophrenia from a genome-wide study of 41,321 subjects

A rare functional noncoding variant at the GWAS-implicated MIR137/MIR2682 locus might confer risk to schizophrenia and bipolar disorder

scientific article

A reference panel of 64,976 haplotypes for genotype imputation

scientific article

Analysis of shared heritability in common disorders of the brain

scientific article published on 21 June 2018

Assessing the impact of population stratification on genetic association studies

scientific article

Association Between Substance Use Disorder And Polygenic Liability To Schizophrenia

Association Between Substance Use Disorder and Polygenic Liability to Schizophrenia

scientific article published on 6 June 2017

Association and linkage disequilibrium between a functional polymorphism of the dopamine-2 receptor gene and schizophrenia in a genetically homogeneous Portuguese population

scientific article published in January 2002

Association between homozygosity at the COMT gene locus and obsessive compulsive disorder

scientific article published on 01 December 2000

Association between schizophrenia and the syntaxin 1A gene.

scientific article published in July 2004

Association of DNA Methylation Differences With Schizophrenia in an Epigenome-Wide Association Study.

scientific article published in May 2016

Association study of 83 candidate genes for bipolar disorder in chromosome 6q selected using an evidence-based prioritization algorithm

scientific article

Biological insights from the whole genome analysis of human embryonic stem cells

scientific article

CNV analysis in a large schizophrenia sample implicates deletions at 16p12.1 and SLC1A1 and duplications at 1p36.33 and CGNL1

scientific article

Clinical features associated with treatment response in obsessive-compulsive disorder.

scientific article published on 19 April 2006

Combined analysis from eleven linkage studies of bipolar disorder provides strong evidence of susceptibility loci on chromosomes 6q and 8q

scientific article

Comorbidity of Obsessive-Compulsive and Psychotic Symptoms: A Review ⬇️

scientific article published on July 1, 1995

Comorbidity of severe psychotic disorders with measures of substance use

scientific article

Complement genes contribute sex-biased vulnerability in diverse disorders

scientific article published on 11 May 2020

Complete maternal uniparental isodisomy of chromosome 4 in a subject with major depressive disorder detected by high density SNP genotyping arrays

scientific article

Contribution of Rare Copy Number Variants to Bipolar Disorder Risk Is Limited to Schizoaffective Cases

scientific article published on 20 December 2018

Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects

scientific article

Contributions of common genetic variants to risk of schizophrenia among individuals of African and Latino ancestry

scientific article published on 07 October 2019

Copy number variation in obsessive-compulsive disorder and tourette syndrome: a cross-disorder study

scientific article

Cross-disorder genome-wide analyses suggest a complex genetic relationship between Tourette's syndrome and OCD.

scientific article

Detection of expansion regions in Portuguese bipolar families

scientific article published in December 2000

Evidence for genetic heterogeneity between clinical subtypes of bipolar disorder

scientific article

Evidence for linkage disequilibrium between the alpha 7-nicotinic receptor gene (CHRNA7) locus and schizophrenia in Azorean families

scientific article published in December 2001

Evidence that duplications of 22q11.2 protect against schizophrenia

scientific article

Extensions of Multiple-Group Item Response Theory Alignment: Application to Psychiatric Phenotypes in an International Genomics Consortium

scientific article published on 05 February 2020

From genomics to proteomics: new directions in molecular neuropsychiatry.

scientific article

GWA study data mining and independent replication identify cardiomyopathy-associated 5 (CMYA5) as a risk gene for schizophrenia

scientific article

GWAS of Suicide Attempt in Psychiatric Disorders and Association With Major Depression Polygenic Risk Scores.

scientific article

Gene Expression in Patient-Derived Neural Progenitors Implicates WNT5A Signaling in the Etiology of Schizophrenia

scientific article published on 22 January 2020

Gene expression analysis of peripheral blood leukocytes from discordant sib-pairs with schizophrenia and bipolar disorder reveals points of convergence between genetic and functional genomic approaches

article

Genetic analyses of schizophrenia

scientific article

Genetic and post-mortem mRNA analysis of the 14-3-3 genes that encode phosphoserine/threonine-binding regulatory proteins in schizophrenia and bipolar disorder.

scientific article

Genetic correlation between smoking behaviors and schizophrenia

scientific article published on 8 March 2017

Genetic differences between five European populations

scientific article published on 08 July 2010

Genetic investigation of chromosome 5q GABAA receptor subunit genes in schizophrenia

scientific article

Genetic linkage of bipolar disorder to chromosome 6q22 is a consistent finding in Portuguese subpopulations and may generalize to broader populations

scientific article

Genetic overlap of schizophrenia and bipolar disorder in a high-density linkage survey in the Portuguese Island population

scientific article published on 27 March 2012

Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs

scientific article

Genetic validation of bipolar disorder identified by automated phenotyping using electronic health records.

scientific article published on 18 April 2018

Genetics of schizophrenia: recent advances.

scientific article published on January 2007

Genome-Wide Association Studies of Schizophrenia and Bipolar Disorder in a Diverse Cohort of US Veterans

scientific article published on 10 November 2020

Genome-wide Burden of Rare Short Deletions Is Enriched in Major Depressive Disorder in Four Cohorts

scientific article published on 13 March 2019

Genome-wide association study identifies 30 loci associated with bipolar disorder.

scientific article

Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology

scientific article published in June 2021

Genome-wide association study of obsessive-compulsive disorder.

scientific article

Genome-wide association study reveals greater polygenic loading for schizophrenia in cases with a family history of illness

scientific article published on 11 December 2015

Genome-wide scan in Portuguese Island families identifies 5q31-5q35 as a susceptibility locus for schizophrenia and psychosis

scientific article

Genome-wide scan in Portuguese Island families implicates multiple loci in bipolar disorder: fine mapping adds support on chromosomes 6 and 11

scientific article published on 01 May 2004

Genomewide linkage analysis of bipolar disorder by use of a high-density single-nucleotide-polymorphism (SNP) genotyping assay: a comparison with microsatellite marker assays and finding of significant linkage to chromosome 6q22.

scientific article

Greater history of traumatic event exposure and PTSD associated with comorbid body dysmorphic disorder in a large OCD cohort

scientific article published on 06 May 2020

Human loss-of-function variants suggest that partial LRRK2 inhibition is a safe therapeutic strategy for Parkinson’s disease

scientific article

Identification of candidate genes for psychosis in rat models, and possible association between schizophrenia and the 14-3-3eta gene

scientific article

In reply

Integrating evolutionary and regulatory information with a multispecies approach implicates genes and pathways in obsessive-compulsive disorder

scientific article published on 17 October 2017

Integrating genetic, functional genomic, and bioinformatics data in a systems biology approach to complex diseases: application to schizophrenia

scientific article

Interaction Testing and Polygenic Risk Scoring to Estimate the Association of Common Genetic Variants With Treatment Resistance in Schizophrenia

scientific article

Interrogating the Genetic Determinants of Tourette's Syndrome and Other Tic Disorders Through Genome-Wide Association Studies

scientific article published on 01 March 2019

LINE1 insertions as a genomic risk factor for schizophrenia: Preliminary evidence from an affected family

scientific article

Linkage disequilibrium and haplotype structure of five GABAA receptor subunit genes investigated for association with schizophrenia

article

Long repeat tracts at SCA8 in major psychosis

scientific article published in December 2000

Mapping genomic loci implicates genes and synaptic biology in schizophrenia

scientific article published on 8 April 2022

Meta-analysis of 32 genome-wide linkage studies of schizophrenia.

scientific article published on 30 December 2008

Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores

scientific article

Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores

New data and an old puzzle: the negative association between schizophrenia and rheumatoid arthritis

scientific article

Nicotine dependence and psychosis in Bipolar disorder and Schizoaffective disorder, Bipolar type

scientific article published on 15 October 2015

Nonparametric linkage analysis between schizophrenia and candidate genes of dopaminergic and serotonergic systems.

scientific article published in April 2004

Objective structured clinical interview training using a virtual human patient.

scientific article published in January 2008

Parental age effects on odor sensitivity in healthy subjects and schizophrenia patients

scientific article published on 29 July 2015

Partitioning the heritability of Tourette syndrome and obsessive compulsive disorder reveals differences in genetic architecture

scientific article published in October 2013

Paternal age effect: Replication in schizophrenia with intriguing dissociation between bipolar with and without psychosis.

scientific article published on 16 July 2015

Perfectionism and eating attitudes in Portuguese students: a longitudinal study.

scientific article published in September 2009

Perfectionism and eating attitudes in Portuguese university students

article

Perfectionism in obsessive-compulsive and eating disorders

scientific article published in December 2009

Rare Copy Number Variants in NRXN1 and CNTN6 Increase Risk for Tourette Syndrome

scientific article published on June 2017

Rare coding variants in ten genes confer substantial risk for schizophrenia

article

Recent findings in the genetics of OCD.

scientific article

Recurrent Rare Copy Number Variants Increase Risk for Esotropia

scientific article published on 01 August 2020

Review of the putative association of dopamine D2 receptor and alcoholism: a meta-analysis

scientific article

Selection of homogeneous populations for genetic study: the Portugal genetics of psychosis project

scientific article

Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders

scientific article

Structural forms of the human amylase locus and their relationships to SNPs, haplotypes and obesity

scientific article

Substance use associated with short sleep duration in patients with schizophrenia or schizoaffective disorder

scientific article published on 8 September 2015

Summary of the Third World Congress on Psychiatric Genetics

scientific article published in December 1993

Support for involvement of neuregulin 1 in schizophrenia pathophysiology

scientific article published on 01 April 2005

Support for involvement of neuregulin 1 in schizophrenia pathophysiology

Symptoms of psychosis in schizophrenia, schizoaffective disorder, and bipolar disorder: A comparison of African Americans and Caucasians in the Genomic Psychiatry Cohort

scientific article

Teaching Scholarly Activity in Psychiatric Training: Years 6 and 7 ⬇️

scientific article published on March 1, 2013

Teaching evidence-based approaches to suicide risk assessment and prevention that enhance psychiatric training

scientific article

The Genomics of Psychiatric Illnesses: Moving Forward

scientific article published on 12 October 2017

The Role of Regional Conferences in Research Resident Career Development: The California Psychiatry Research Resident Retreat

scientific article published on 13 May 2016

The effect of LRRK2 loss-of-function variants in humans

scientific article published on 27 May 2020

The genetics of obsessive-compulsive disorder

scientific article

The genomic psychiatry cohort: partners in discovery

scientific article published on 03 May 2013

Transforming residency training: a case study

scientific article

Treatment non-response in OCD: methodological issues and operational definitions

scientific article

Uncovering the hidden risk architecture of the schizophrenias: confirmation in three independent genome-wide association studies

scientific article (publication date: February 2015)

Using consensus OPCRIT diagnoses. An efficient procedure for best-estimate lifetime diagnoses

scientific article published on August 1999

Virtual patients as novel teaching tools in psychiatry

scientific article published in September 2012

What to learn and how to teach it: five years of pre-meetings for training directors in psychiatry

scientific article published on March 2013

Why I Like Being an Academic Psychiatrist

scientific article published on September 1, 2012

List of works by Michele T Pato

A comprehensive family-based replication study of schizophrenia genes

A contribution of novel CNVs to schizophrenia from a genome-wide study of 41,321 subjects

A rare functional noncoding variant at the GWAS-implicated MIR137/MIR2682 locus might confer risk to schizophrenia and bipolar disorder

A reference panel of 64,976 haplotypes for genotype imputation

Analysis of shared heritability in common disorders of the brain

Assessing the impact of population stratification on genetic association studies

Association Between Substance Use Disorder And Polygenic Liability To Schizophrenia

Association Between Substance Use Disorder and Polygenic Liability to Schizophrenia

Association and linkage disequilibrium between a functional polymorphism of the dopamine-2 receptor gene and schizophrenia in a genetically homogeneous Portuguese population

Association between homozygosity at the COMT gene locus and obsessive compulsive disorder

Association between schizophrenia and the syntaxin 1A gene.

Association of DNA Methylation Differences With Schizophrenia in an Epigenome-Wide Association Study.

Association study of 83 candidate genes for bipolar disorder in chromosome 6q selected using an evidence-based prioritization algorithm

Biological insights from the whole genome analysis of human embryonic stem cells

CNV analysis in a large schizophrenia sample implicates deletions at 16p12.1 and SLC1A1 and duplications at 1p36.33 and CGNL1

Clinical features associated with treatment response in obsessive-compulsive disorder.

Combined analysis from eleven linkage studies of bipolar disorder provides strong evidence of susceptibility loci on chromosomes 6q and 8q

Comorbidity of Obsessive-Compulsive and Psychotic Symptoms: A Review ⬇️

Comorbidity of severe psychotic disorders with measures of substance use

Complement genes contribute sex-biased vulnerability in diverse disorders

Complete maternal uniparental isodisomy of chromosome 4 in a subject with major depressive disorder detected by high density SNP genotyping arrays

Contribution of Rare Copy Number Variants to Bipolar Disorder Risk Is Limited to Schizoaffective Cases

Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects

Contributions of common genetic variants to risk of schizophrenia among individuals of African and Latino ancestry

Copy number variation in obsessive-compulsive disorder and tourette syndrome: a cross-disorder study

Cross-disorder genome-wide analyses suggest a complex genetic relationship between Tourette's syndrome and OCD.

Detection of expansion regions in Portuguese bipolar families

Evidence for genetic heterogeneity between clinical subtypes of bipolar disorder

Evidence for linkage disequilibrium between the alpha 7-nicotinic receptor gene (CHRNA7) locus and schizophrenia in Azorean families

Evidence that duplications of 22q11.2 protect against schizophrenia

Extensions of Multiple-Group Item Response Theory Alignment: Application to Psychiatric Phenotypes in an International Genomics Consortium

From genomics to proteomics: new directions in molecular neuropsychiatry.

GWA study data mining and independent replication identify cardiomyopathy-associated 5 (CMYA5) as a risk gene for schizophrenia

GWAS of Suicide Attempt in Psychiatric Disorders and Association With Major Depression Polygenic Risk Scores.

Gene Expression in Patient-Derived Neural Progenitors Implicates WNT5A Signaling in the Etiology of Schizophrenia

Gene expression analysis of peripheral blood leukocytes from discordant sib-pairs with schizophrenia and bipolar disorder reveals points of convergence between genetic and functional genomic approaches

Genetic analyses of schizophrenia

Genetic and post-mortem mRNA analysis of the 14-3-3 genes that encode phosphoserine/threonine-binding regulatory proteins in schizophrenia and bipolar disorder.

Genetic correlation between smoking behaviors and schizophrenia

Genetic differences between five European populations

Genetic investigation of chromosome 5q GABAA receptor subunit genes in schizophrenia

Genetic linkage of bipolar disorder to chromosome 6q22 is a consistent finding in Portuguese subpopulations and may generalize to broader populations

Genetic overlap of schizophrenia and bipolar disorder in a high-density linkage survey in the Portuguese Island population

Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs

Genetic validation of bipolar disorder identified by automated phenotyping using electronic health records.

Genetics of schizophrenia: recent advances.

Genome-Wide Association Studies of Schizophrenia and Bipolar Disorder in a Diverse Cohort of US Veterans

Genome-wide Burden of Rare Short Deletions Is Enriched in Major Depressive Disorder in Four Cohorts

Genome-wide association study identifies 30 loci associated with bipolar disorder.

Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology

Genome-wide association study of obsessive-compulsive disorder.

Genome-wide association study reveals greater polygenic loading for schizophrenia in cases with a family history of illness

Genome-wide scan in Portuguese Island families identifies 5q31-5q35 as a susceptibility locus for schizophrenia and psychosis

Genome-wide scan in Portuguese Island families implicates multiple loci in bipolar disorder: fine mapping adds support on chromosomes 6 and 11

Genomewide linkage analysis of bipolar disorder by use of a high-density single-nucleotide-polymorphism (SNP) genotyping assay: a comparison with microsatellite marker assays and finding of significant linkage to chromosome 6q22.

Greater history of traumatic event exposure and PTSD associated with comorbid body dysmorphic disorder in a large OCD cohort

Human loss-of-function variants suggest that partial LRRK2 inhibition is a safe therapeutic strategy for Parkinson’s disease

Identification of candidate genes for psychosis in rat models, and possible association between schizophrenia and the 14-3-3eta gene

In reply

Integrating evolutionary and regulatory information with a multispecies approach implicates genes and pathways in obsessive-compulsive disorder

Integrating genetic, functional genomic, and bioinformatics data in a systems biology approach to complex diseases: application to schizophrenia

Interaction Testing and Polygenic Risk Scoring to Estimate the Association of Common Genetic Variants With Treatment Resistance in Schizophrenia

Interrogating the Genetic Determinants of Tourette's Syndrome and Other Tic Disorders Through Genome-Wide Association Studies

LINE1 insertions as a genomic risk factor for schizophrenia: Preliminary evidence from an affected family

Linkage disequilibrium and haplotype structure of five GABAA receptor subunit genes investigated for association with schizophrenia

Long repeat tracts at SCA8 in major psychosis

Mapping genomic loci implicates genes and synaptic biology in schizophrenia

Meta-analysis of 32 genome-wide linkage studies of schizophrenia.

Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores

Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores

New data and an old puzzle: the negative association between schizophrenia and rheumatoid arthritis

Nicotine dependence and psychosis in Bipolar disorder and Schizoaffective disorder, Bipolar type

Nonparametric linkage analysis between schizophrenia and candidate genes of dopaminergic and serotonergic systems.

Objective structured clinical interview training using a virtual human patient.

Parental age effects on odor sensitivity in healthy subjects and schizophrenia patients

Partitioning the heritability of Tourette syndrome and obsessive compulsive disorder reveals differences in genetic architecture

Paternal age effect: Replication in schizophrenia with intriguing dissociation between bipolar with and without psychosis.

Perfectionism and eating attitudes in Portuguese students: a longitudinal study.

Perfectionism and eating attitudes in Portuguese university students