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List of works by Bruno Pradines

1H-1,2,3-triazole tethered isatin-ferrocene conjugates: Synthesis and in vitro antimalarial evaluation

scientific article published on 13 October 2014

A Worldwide Map of Plasmodium falciparum K13-Propeller Polymorphisms.

scientific article

Absence of Association between Polymorphisms in the RING E3 Ubiquitin Protein Ligase Gene and Ex Vivo Susceptibility to Conventional Antimalarial Drugs in Plasmodium falciparum Isolates from Dakar, Senegal

scientific article published on 16 May 2016

Absence of a High Level of Duplication of the Plasmepsin II Gene in Africa

article

Absence of association between Plasmodium falciparum small sub-unit ribosomal RNA gene mutations and in vitro decreased susceptibility to doxycycline

scientific article

Absence of association between piperaquine in vitro responses and polymorphisms in the pfcrt, pfmdr1, pfmrp, and pfnhe genes in Plasmodium falciparum

scientific article published on 14 June 2010

Absence of association between polymorphisms in the K13 gene and the presence of Plasmodium falciparum parasites at day 3 after treatment with artemisinin derivatives in Senegal

scientific article published on 24 April 2017

Absence of association between pyronaridine in vitro responses and polymorphisms in genes involved in quinoline resistance in Plasmodium falciparum ⬇️

scientific article published on November 25, 2010

Airport malaria

scientific article published on 17 March 2009

Albumin-bound nanoparticles of practically water-insoluble antimalarial lead greatly enhance its efficacy

scientific article published on 8 January 2014

Antibiotics in malaria therapy: which antibiotics except tetracyclines and macrolides may be used against malaria?

scientific article

Antibody response against saliva antigens of Anopheles gambiae and Aedes aegypti in travellers in tropical Africa

scientific article published on 07 August 2007

Antibody responses to several malaria pre-erythrocytic antigens as a marker of malaria exposure among travelers

scientific article published in June 2006

Antimalarial acridines: synthesis, in vitro activity against P. falciparum and interaction with hematin

scientific article published on 9 October 2009

Antimalarial drug use in general populations of tropical Africa

scientific article

Antimalarial versus cytotoxic properties of dual drugs derived from 4-aminoquinolines and Mannich bases: interaction with DNA.

scientific article published on April 2010

Apparent absence of atovaquone/proguanil resistance in 477 Plasmodium falciparum isolates from untreated French travellers

scientific article published on 30 November 2005

Artesunate tolerance in transgenic Plasmodium falciparum parasites overexpressing a tryptophan-rich protein

scientific article

Arylsulfonyl acridinyl derivatives acting on Plasmodium falciparum

scientific article published in September 2004

Assessment of Plasmodium falciparum resistance to ferroquine (SSR97193) in field isolates and in W2 strain under pressure

scientific article

Association between Polymorphisms in the Pfmdr6 Gene and Ex Vivo Susceptibility to Quinine in Plasmodium falciparum Parasites from Dakar, Senegal

scientific article published on 4 January 2017

Atorvastatin as a potential anti-malarial drug: in vitro synergy in combinational therapy with quinine against Plasmodium falciparum

scientific article published on 25 May 2010

Atorvastatin as a potential antimalarial drug: in vitro synergy in combinational therapy with dihydroartemisinin

scientific article published on 30 November 2009

Atorvastatin is 10-fold more active in vitro than other statins against Plasmodium falciparum

scientific article published on 14 May 2007

Atorvastatin is a promising partner for antimalarial drugs in treatment of Plasmodium falciparum malaria

scientific article published on 23 March 2009

Atorvastatin treatment is effective when used in combination with mefloquine in an experimental cerebral malaria murine model ⬇️

scientific article published on January 10, 2012

Atypical aetiology of a conjugal fever: autochthonous airport malaria between Paris and French Riviera: a case report

scientific article

Cellular uptake of a catechol iron chelator and chloroquine into Plasmodium falciparum infected erythrocytes ⬇️

scientific article published on April 15, 2003

Characterization of Plasmodium falciparum genes associated with drug resistance in Hodh Elgharbi, a malaria hotspot near Malian-Mauritanian border

scientific article published on 05 April 2017

Chemosensitizers in drug transport mechanisms involved in protozoan resistance

scientific article

Chloroquine resistance reversal agents as promising antimalarial drugs

scientific article published on August 2006

Confirmation of Plasmodium falciparum in vitro resistance to monodesethylamodiaquine and chloroquine in Dakar, Senegal, in 2015.

scientific article published on 16 March 2017

Delayed Onset of Plasmodium falciparum Malaria after Doxycycline Prophylaxis in a Soldier Returning from the Central African Republic

scientific article published on 8 February 2016

Design, synthesis, and antimalarial activity of structural chimeras of thiosemicarbazone and ferroquine analogues

scientific article published on 5 October 2007

Determinants of compliance with anti-vectorial protective measures among non-immune travellers during missions to tropical Africa ⬇️

scientific article published on August 10, 2011

Determinants of compliance with malaria chemoprophylaxis among French soldiers during missions in inter-tropical Africa

scientific article

Differential association of Plasmodium falciparum Na+/H+ exchanger polymorphism and quinine responses in field- and culture-adapted isolates of Plasmodium falciparum

scientific article published on 26 September 2011

Dihydroethanoanthracene derivatives as in vitro malarial chloroquine resistance reversal agents

scientific article

Dihydroethanoanthracene derivatives reverse in vitro quinoline resistance in Plasmodium falciparum malaria

scientific article published on September 2008

Dose Responses of Proveblue Methylene Blue in an Experimental Murine Cerebral Malaria Model ⬇️

scientific article published on May 13, 2013

Early treatment failure during treatment of Plasmodium falciparum malaria with atovaquone-proguanil in the Republic of Ivory Coast

scientific article

Efficacy of proveblue (methylene blue) in an experimental cerebral malaria murine model

scientific article published on 22 April 2013

Emergence of Mutations in the K13 Propeller Gene of Plasmodium falciparum Isolates from Dakar, Senegal, in 2013-2014.

scientific article

Enhancement of the antimalarial activity of ciprofloxacin using a double prodrug/bioorganometallic approach

scientific article

Epidemiology of malaria

scientific article published in April 2005

Ex vivo activity of Proveblue, a methylene blue, against field isolates of Plasmodium falciparum in Dakar, Senegal from 2013-2015.

scientific article published on 6 July 2017

Ex vivo activity of the ACT new components pyronaridine and piperaquine in comparison with conventional ACT drugs against isolates of Plasmodium falciparum

scientific article published on 14 February 2012

Ex vivo susceptibility of Plasmodium falciparum isolates from Dakar, Senegal, to seven standard anti-malarial drugs ⬇️

scientific article published on October 20, 2011

Factors associated with malaria chemoprophylaxis compliance among French service members deployed in Central African Republic

scientific article published on 17 March 2016

Failure of dihydroartemisinin plus piperaquine treatment of falciparum malaria by under-dosing in an overweight patient

scientific article published on 20 September 2016

First case of emergence of atovaquone-proguanil resistance in Plasmodium falciparum during treatment in a traveler in Comoros

scientific article published on 14 April 2008

Genetic diversity and structure of African Plasmodium falciparum populations in urban and rural areas

scientific article

Genetic structure of Plasmodium falciparum and elimination of malaria, Comoros archipelago

scientific article published on November 2010

High prevalence of Plasmodium falciparum antimalarial drug resistance markers in isolates from asymptomatic patients from the Republic of the Congo between 2010 and 2015

article by Dominique Fatima Voumbo-Matoumona et al published 16 August 2018 in Journal of global antimicrobial resistance

High-throughput analysis of antimalarial susceptibility data by the worldwide antimalarial resistance network (WWARN) In Vitro analysis and reporting tool

scientific article

Impact of methylene blue and atorvastatin combination therapy on the apparition of cerebral malaria in a murine model

scientific article published on 15 April 2013

Improvement of the efficacy of dihydroartemisinin with atorvastatin in an experimental cerebral malaria murine model

scientific article published on 30 August 2013

In Vitro Activity of Proveblue (Methylene Blue) on Plasmodium falciparum Strains Resistant to Standard Antimalarial Drugs ⬇️

scientific article published on February 22, 2011

In vitro activity of ferroquine is independent of polymorphisms in transport protein genes implicated in quinoline resistance in Plasmodium falciparum

scientific article published on 27 May 2008

In vitro activity of tafenoquine against the asexual blood stages of Plasmodium falciparum isolates from Gabon, Senegal, and Djibouti

scientific article published in September 2006

In vitro efficiency of new acridyl derivatives against Plasmodium falciparum

scientific article published on 16 February 2007

In vitro increase in chloroquine accumulation induced by dihydroethano- and ethenoanthracene derivatives in Plasmodium falciparum-parasitized erythrocytes

scientific article published on July 2002

In vitro interaction of lumefantrine and piperaquine by atorvastatin against Plasmodium falciparum

scientific article

In vitro piperaquine susceptibility is not associated with the Plasmodium falciparum chloroquine resistance transporter gene

scientific article

In vitro potentiation of antibiotic activities by a catecholate iron chelator against chloroquine-resistant Plasmodium falciparum

scientific article

In vitro reversal of chloroquine resistance in Plasmodium falciparum with dihydroethanoanthracene derivatives.

scientific article published on June 2002

In vitro susceptibility to pyrimethamine of DHFR I164L single mutant Plasmodium falciparum

scientific article

In vitro susceptibility to quinine and microsatellite variations of the Plasmodium falciparum Na+/H+ exchanger (Pfnhe-1) gene: the absence of association in clinical isolates from the Republic of Congo

scientific article published on 11 February 2011

In vitro susceptibility to quinine and microsatellite variations of the Plasmodium falciparum Na+/H+ exchanger transporter (Pfnhe-1) gene in 393 isolates from Dakar, Senegal ⬇️

scientific article published on 07 June 2013

Influence of oxygen on asexual blood cycle and susceptibility of Plasmodium falciparum to chloroquine: requirement of a standardized in vitro assay

scientific article published on 16 April 2007

Inhibition of efflux of quinolines as new therapeutic strategy in malaria.

scientific article

K13-Propeller Polymorphisms in Plasmodium falciparum Isolates from Patients in Mayotte in 2013 and 2014

scientific article

Limited polymorphisms in k13 gene in Plasmodium falciparum isolates from Dakar, Senegal in 2012-2013

scientific article

Longitudinal study assessing the return of chloroquine susceptibility of Plasmodium falciparum in isolates from travellers returning from West and Central Africa, 2000-2011

scientific article published on 25 January 2013

Macrolides and associated antibiotics based on similar mechanism of action like lincosamides in malaria

scientific article published on 12 February 2016

Malaria Prophylaxis Failure with Doxycycline, Central African Republic, 2014.

scientific article published on August 2015

Malaria burden and anti-malarial drug efficacy in Owando, northern Congo

scientific article

Malaria epidemic and drug resistance, Djibouti

scientific article published in February 2005

Malaria prevalence and morbidity among children reporting at health facilities in Nouakchott, Mauritania ⬇️

scientific article published on October 21, 2011

Malaria transmission and insecticide resistance of Anopheles gambiae in Libreville and Port-Gentil, Gabon ⬇️

scientific article published on November 11, 2010

Malaria transmission in Dakar: a two-year survey

scientific article published on 16 September 2008

Malaria, tuberculosis and HIV: what's new? Contribution of the Institut Hospitalo-Universitaire Méditerranée Infection in updated data

article

Marseilles: a surveillance site for malaria from the Comoros Islands

scientific article published in May 2004

Medical Entomology: A Reemerging Field of Research to Better Understand Vector-Borne Infectious Diseases

scientific article published on August 2017

Metal-chloroquine derivatives as possible anti-malarial drugs: evaluation of anti-malarial activity and mode of action

scientific article

Modeling of Plasmodium falciparum-infected erythrocyte cytoadhesion in microvascular conditions: chondroitin-4-sulfate binding, A competitive phenotype

scientific article published on 30 December 2002

Molecular Markers and In Vitro Susceptibility to Doxycycline in Plasmodium falciparum Isolates from Thailand

scientific article published on 8 June 2015

Molecular surveillance of drug-resistant Plasmodium vivax using pvdhfr, pvdhps and pvmdr1 markers in Nouakchott, Mauritania

scientific article published on 14 November 2011

Multinormal in vitro distribution model suitable for the distribution of Plasmodium falciparum chemosusceptibility to doxycycline

scientific article

Multinormal in vitro distribution of Plasmodium falciparum susceptibility to piperaquine and pyronaridine

scientific article

Orally active antimalarials: hydrolytically stable derivatives of 10-trifluoromethyl anhydrodihydroartemisinin

scientific article published in March 2004

Pfhrp2 and pfhrp3 polymorphisms in Plasmodium falciparum isolates from Dakar, Senegal: impact on rapid malaria diagnostic tests

scientific article published on 24 January 2013

PftetQ and pfmdt copy numbers as predictive molecular markers of decreased ex vivo doxycycline susceptibility in imported Plasmodium falciparum malaria

scientific article

Plasmodium falciparum In Vitro Resistance to Monodesethylamodiaquine, Dakar, Senegal, 2014.

scientific article published on May 2016

Plasmodium falciparum Na+/H+ exchanger 1 transporter is involved in reduced susceptibility to quinine

scientific article published on 09 March 2009

Plasmodium falciparum Recrudescence Two Years after Treatment of an Uncomplicated Infection without Return to an Area Where Malaria Is Endemic

scientific article published on 11 December 2017

Plasmodium falciparum proteome changes in response to doxycycline treatment

scientific article

Plasmodium falciparum susceptibility to anti-malarial drugs in Dakar, Senegal, in 2010: an ex vivo and drug resistance molecular markers study ⬇️

scientific article published on March 20, 2013

Plasmodium falciparum susceptibility to standard and potential anti-malarial drugs in Dakar, Senegal, during the 2013-2014 malaria season

scientific article

Plasmodium falciparumwith Multidrug Resistance 1 Gene Duplications, Senegal ⬇️

scientific article published on May 1, 2013

Plasmodium vivax and Plasmodium falciparum infections in the Republic of Djibouti: evaluation of their prevalence and potential determinants ⬇️

scientific article published on November 28, 2012

Polymorphism in plasmodium falciparum drug transporter proteins and reversal of in vitro chloroquine resistance by a 9,10-dihydroethanoanthracene derivative

scientific article published on December 2004

Population genetics analysis during the elimination process of Plasmodium falciparum in Djibouti ⬇️

scientific article published on June 13, 2013

Prevalence of anti-malarial resistance genes in Dakar, Senegal from 2013 to 2014.

scientific article published on 07 July 2016

Prevalence of antimalarial drug resistance genes in Southeastern Gabon from 2011 to 2014

article

Prevalence of in vitro resistance to eleven standard or new antimalarial drugs among Plasmodium falciparum isolates from Pointe-Noire, Republic of the Congo

scientific article

Prevalence of molecular markers of Plasmodium falciparum drug resistance in Dakar, Senegal ⬇️

scientific article published on June 13, 2012

Probing the role of the covalent linkage of ferrocene into a chloroquine template

scientific article published on July 2006

Proveblue (Methylene Blue) as an Antimalarial Agent: In Vitro Synergy with Dihydroartemisinin and Atorvastatin ⬇️

scientific article published on March 5, 2012

Quinine-resistant malaria in traveler returning from French Guiana, 2010.

scientific article published on May 2011

Quinine-resistant malaria in traveler returning from Senegal, 2007

scientific article published in March 2010

Rapid dissemination of Plasmodium falciparum drug resistance despite strictly controlled antimalarial use

scientific article

Reduced in vitro susceptibility to artemisinin derivatives associated with multi-resistance in a traveller returning from South-East Asia

scientific article

Remote sensing and malaria risk for military personnel in Africa

scientific article published on July 2008

Role of Pfmdr1 in in vitro Plasmodium falciparum susceptibility to chloroquine, quinine, monodesethylamodiaquine, mefloquine, lumefantrine, and dihydroartemisinin

scientific article

Salivary gland protein repertoire from Aedes aegypti mosquitoes

scientific article published in May 2010

Surveillance of travellers: an additional tool for tracking antimalarial drug resistance in endemic countries

scientific article (publication date: 2013)

Susceptibility of Plasmodium falciparum isolates to doxycycline is associated with pftetQ sequence polymorphisms and pftetQ and pfmdt copy numbers

scientific article published in January 2010

Synergy of mefloquine activity with atorvastatin, but not chloroquine and monodesethylamodiaquine, and association with the pfmdr1 gene

scientific article published on 25 May 2010

Synthesis and Biological Evaluation of Acridine Derivatives as Antimalarial Agents ⬇️

scientific article published on February 13, 2012

Synthesis and antimalarial activities of rhenium bioorganometallics based on the 4-aminoquinoline structure ⬇️

scientific article published on September 19, 2010

Synthesis and effects on chloroquine susceptibility in Plasmodium falciparum of a series of new dihydroanthracene derivatives

scientific article published on July 2002

Tetracyclines in malaria

scientific article

The D113N mutation in the RING E3 ubiquitin protein ligase gene is not associated with ex vivo susceptibility to common anti-malarial drugs in African Plasmodium falciparum isolates

scientific article published on 12 March 2018

The F423Y mutation in the pfmdr2 gene and mutations N51I, C59R, and S108N in the pfdhfr gene are independently associated with pyrimethamine resistance in Plasmodium falciparum isolates

scientific article

The Plasmodium falciparum chloroquine resistance transporter is associated with the ex vivo P. falciparum African parasite response to pyronaridine

scientific article published on 9 February 2016

The Redox Cycler Plasmodione Is a Fast-Acting Antimalarial Lead Compound with Pronounced Activity against Sexual and Early Asexual Blood-Stage Parasites

scientific article

The antimalarial ferroquine: role of the metal and intramolecular hydrogen bond in activity and resistance

scientific article published on 7 January 2011

The end of a dogma: the safety of doxycycline use in young children for malaria treatment

scientific article

Urban malaria in Dakar, Senegal: chemosusceptibility and genetic diversity of Plasmodium falciparum isolates.

scientific article

Use of the atmospheric generators for capnophilic bacteria Genbag-CO2 for the evaluation of in vitro Plasmodium falciparum susceptibility to standard anti-malarial drugs ⬇️

scientific article published on January 14, 2011

Vivax malaria in Mauritania includes infection of a Duffy-negative individual

scientific article published in 2011

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