List of works by Bernhards Ogutu

A Multinational Trial of Prasugrel for Sickle Cell Vaso-Occlusive Events

scientific article

A Spatiotemporal Analysis of HIV-Associated Mortality in Rural Western Kenya 2011-2015

scientific article published on 01 August 2018

A controlled, parallel, cluster-randomized trial of community-wide screening and treatment of asymptomatic carriers of Plasmodium falciparum in Burkina Faso

scientific article published on 27 February 2013

A phase 3 trial of RTS,S/AS01 malaria vaccine in African infants

scientific article

Adenovirus type 35-vectored tuberculosis vaccine has an acceptable safety and tolerability profile in healthy, BCG-vaccinated, QuantiFERON(®)-TB Gold (+) Kenyan adults without evidence of tuberculosis

scientific article

African Pharmacogenomics Consortium: Consolidating pharmacogenomics knowledge, capacity development and translation in Africa

scientific article published on 04 June 2019

Alcohol consumption and hazardous drinking in western Kenya--a household survey in a health and demographic surveillance site

scientific article published on 25 September 2015

Antimalarials: Molecular Drug Targets and Mechanism of Action

scientific article published on 30 January 2017

Artemether and lumefantrine for the treatment of uncomplicated Plasmodium falciparum malaria in sub-Saharan Africa

scientific article published on 18 February 2013

Assessment of inpatient paediatric care in first referral level hospitals in 13 districts in Kenya

scientific article published on June 2004

Baseline data of parasite clearance in patients with falciparum malaria treated with an artemisinin derivative: an individual patient data meta-analysis

scientific article

Bullous erythema multiforme after treatment with Malarone, a combination antimalarial composed of atovaquone and proguanil hydrochloride

scientific article published in July 2008

Burden, features, and outcome of neurological involvement in acute falciparum malaria in Kenyan children

scientific article published on May 2007

Cardiovascular safety and population pharmacokinetic properties of piperaquine in African patients with uncomplicated falciparum malaria - a pooled multicentre analysis

scientific article published on 20 April 2020

Care-Seeking Dynamics among Patients with Diabetes Mellitus and Hypertension in Selected Rural Settings in Kenya

scientific article published on 06 June 2019

Cause-specific mortality in the Kombewa health and demographic surveillance systems site, rural Western Kenya from 2011-2015.

scientific article

Changes in Serological Immunology Measures in UK and Kenyan Adults Post-controlled Human Malaria Infection

scientific article published on 13 October 2016

Characterization of Plasmodium ovale curtisi and P. ovale wallikeri in Western Kenya utilizing a novel species-specific real-time PCR assay

scientific article published on 15 January 2015

Clinical trials in low-resource settings: the perspectives of caregivers of paediatric participants from Uganda, Tanzania and Kenya

scientific article published on 01 July 2019

Common mental disorder in Nyanza province, Kenya in 2013 and its associated risk factors--an assessment of change since 2004, using a repeat household survey in a demographic surveillance site

scientific article published on 9 December 2015

Communities and Clinical Trials: A Case Study from the RTS,S Malaria Vaccine Trials in Eastern Africa

scientific article published on 26 August 2020

Community screening and treatment of asymptomatic carriers of Plasmodium falciparum with artemether-lumefantrine to reduce malaria disease burden: a modelling and simulation analysis.

scientific article

Comparison of artesunate-mefloquine and artemether-lumefantrine fixed-dose combinations for treatment of uncomplicated Plasmodium falciparum malaria in children younger than 5 years in sub-Saharan Africa: a randomised, multicentre, phase 4 trial

scientific article published on 15 July 2016

Comparison of azithromycin plus chloroquine versus artemether-lumefantrine for the treatment of uncomplicated Plasmodium falciparum malaria in children in Africa: a randomized, open-label study

scientific article

Controlled human malaria infection in Kenyan adults: A safe model that could accelerate assessment of novel drugs and vaccines in malaria endemic populations.

scientific article published on 22 September 2014

Controlled human malaria infections using aseptic, purified cryopreserved Plasmodium falciparum sporozoites administered by needle and syringe

scientific article published on 22 September 2014

Data safety and monitoring boards for African clinical trials

scientific article

Decorticate, decerebrate and opisthotonic posturing and seizures in Kenyan children with cerebral malaria

scientific article published on 7 December 2005

Delivery of paediatric care at the first-referral level in Kenya

scientific article published on October 2004

Development of a pediatric formulation for treatment of P. falciparum malaria: Coartem® (artemether-lumefantrine) Dispersible

scientific article published on 22 September 2014

Development of standardized laboratory methods and quality processes for a phase III study of the RTS, S/AS01 candidate malaria vaccine

scientific article published on 4 August 2011

Development, characterization and antimalarial efficacy of dihydroartemisinin loaded solid lipid nanoparticles

scientific article published on 24 December 2015

Dosing of Ceftriaxone and Metronidazole for Children With Severe Acute Malnutrition.

scientific article published on 25 March 2018

Efficacy and safety of a combination of azithromycin and chloroquine for the treatment of uncomplicated Plasmodium falciparum malaria in two multi-country randomised clinical trials in African adults

scientific article

Efficacy and safety of artemether-lumefantrine dispersible tablets compared with crushed commercial tablets in African infants and children with uncomplicated malaria: a randomised, single-blind, multicentre trial

scientific article

Efficacy and tolerability of artemisinin-based and quinine-based treatments for uncomplicated falciparum malaria in pregnancy: a systematic review and individual patient data meta-analysis

scientific article published on 29 April 2020

Establishing a malaria diagnostics centre of excellence in Kisumu, Kenya

scientific article published on 12 June 2007

Evaluating controlled human malaria infection in Kenyan adults with varying degrees of prior exposure to Plasmodium falciparum using sporozoites administered by intramuscular injection

scientific article

Evaluation of a laboratory quality assurance pilot programme for malaria diagnostics in low-transmission areas of Kenya, 2013.

scientific article

Evaluation of recurrent parasitemia after artemether-lumefantrine treatment for uncomplicated malaria in children in western Kenya

scientific article

Experience and challenges from clinical trials with malaria vaccines in Africa

scientific article published on 4 March 2013

Factors associated with malaria microscopy diagnostic performance following a pilot quality-assurance programme in health facilities in malaria low-transmission areas of Kenya, 2014.

scientific article published on 13 September 2017

Feasibility and cost of using mobile phones for capturing drug safety information in peri-urban settlement in Ghana: a prospective cohort study of patients with uncomplicated malaria.

scientific article

Field evaluation of diagnostic performance of malaria rapid diagnostic tests in western Kenya

scientific article published on 07 September 2016

First results of phase 3 trial of RTS,S/AS01 malaria vaccine in African children

scientific article

Fixed dose artesunate amodiaquine - a phase IIb, randomized comparative trial with non-fixed artesunate amodiaquine

scientific article

Genotypic Variability of HIV-1 Reverse Transcriptase Gene from Long-Term Antiretroviral-Experienced Patients in Kenya

scientific article published on 31 March 2015

Geographic Differences in Phenotype and Treatment of Children with Sickle Cell Anemia from the Multinational DOVE Study

scientific article published on 17 November 2019

Global sequence variation in the histidine-rich proteins 2 and 3 of Plasmodium falciparum: implications for the performance of malaria rapid diagnostic tests

scientific article published on 17 May 2010

Glucose-6-phosphate dehydrogenase deficiency and reduced haemoglobin levels in African children with severe malaria

scientific article published on 07 July 2016

HIV-1 subtype diversity based on envelope C2V3 sequences from Kenyan patients on highly active antiretroviral therapy

scientific article published on 18 December 2014

Health & demographic surveillance system profile: The Kombewa health and demographic surveillance system (Kombewa HDSS).

scientific article

Hypothetical performance of syndrome-based management of acute paediatric admissions of children aged more than 60 days in a Kenyan district hospital

scientific article published on 16 May 2003

Immunogenicity of the RTS,S/AS01 malaria vaccine and implications for duration of vaccine efficacy: secondary analysis of data from a phase 3 randomised controlled trial

scientific article

Implementation of a structured paediatric admission record for district hospitals in Kenya--results of a pilot study

scientific article

Incidence and outcome of convulsive status epilepticus in Kenyan children: a cohort study

scientific article

Increased sample volume and use of quantitative reverse-transcription PCR can improve prediction of liver-to-blood inoculum size in controlled human malaria infection studies

scientific article

Increased systemic exposures of artemether and dihydroartemisinin in infants under 5 kg with uncomplicated Plasmodium falciparum malaria treated with artemether-lumefantrine (Coartem®).

scientific article published on 15 April 2015

Increasing Diversity of HIV-1 Based on Envelope and Pol-RT Sequences of Viruses Circulating among Antiretroviral Experienced Kenyans

scholarly article by Rose C. Kitawi published in October 2014

Intramuscular Artesunate for Severe Malaria in African Children: A Multicenter Randomized Controlled Trial

scientific article

Lessons learnt from the first controlled human malaria infection study conducted in Nairobi, Kenya

scientific article published on 28 April 2015

Liquid chromatography–tandem mass spectrometry for the simultaneous quantitation of ceftriaxone, metronidazole and hydroxymetronidazole in plasma from seriously ill, severely malnourished children

scientific article published in January 2017

Longitudinal estimation of Plasmodium falciparum prevalence in relation to malaria prevention measures in six sub-Saharan African countries

scientific article published on 27 October 2017

Longitudinal study on Plasmodium falciparum gametocyte carriage following artemether-lumefantrine administration in a cohort of children aged 12-47 months living in Western Kenya, a high transmission area

scientific article

Malaria and mental disorder: a population study in an area endemic for malaria in Kenya

scientific article published on October 2017

Malaria mortality estimates: need for agreeable approach

scientific article published on 29 November 2012

Malaria treatment with atovaquone-proguanil in malaria-immune adults: implications for malaria intervention trials and for pre-exposure prophylaxis of malaria

scientific article published on 11 February 2008

Malaria, mental disorders, immunity and their inter-relationships - A cross sectional study in a household population in a health and demographic surveillance site in Kenya

scientific article published on 11 December 2018

Misclassification of Plasmodium infections by conventional microscopy and the impact of remedial training on the proficiency of laboratory technicians in species identification

scientific article published on 27 March 2013

Mitigating the threat of artemisinin resistance in Africa: improvement of drug-resistance surveillance and response systems

scientific article

Molecular markers of anti-malarial drug resistance in Central, West and East African children with severe malaria

scientific article

Open-source mobile digital platform for clinical trial data collection in low-resource settings

scientific article

Pharmacokinetic evaluation of intravenous artesunate in adults with uncomplicated falciparum malaria in Kenya: a phase II study

scientific article

Phase 2a, Open-Label, 4-Escalating-Dose, Randomized Multicenter Study Evaluating the Safety and Activity of Ferroquine (SSR97193) Plus Artesunate, versus Amodiaquine Plus Artesunate, in African Adult Men with Uncomplicated Plasmodium falciparum Mala

scientific article

Pilot assessment of the sensitivity of the malaria thin film

scientific article

Plasmodium falciparum malaria parasite var gene expression is modified by host antibodies: longitudinal evidence from controlled infections of Kenyan adults with varying natural exposure

scientific article published on 23 August 2017

Polymorphisms in Plasmodium falciparum chloroquine resistance transporter and multidrug resistance 1 genes: parasite risk factors that affect treatment outcomes for P. falciparum malaria after artemether-lumefantrine and artesunate-amodiaquine

scientific article

Population pharmacokinetics and pharmacodynamic considerations of amodiaquine and desethylamodiaquine in Kenyan adults with uncomplicated malaria receiving artesunate-amodiaquine combination therapy

scientific article

Population pharmacokinetics and pharmacodynamics of the artesunate-mefloquine fixed dose combination for the treatment of uncomplicated falciparum malaria in African children

scientific article published on 18 April 2019

Pregnancy outcomes and risk of placental malaria after artemisinin-based and quinine-based treatment for uncomplicated falciparum malaria in pregnancy: a WorldWide Antimalarial Resistance Network systematic review and individual patient data meta-an

scientific article published on 02 June 2020

Preparation, characterization, and optimization of primaquine-loaded solid lipid nanoparticles

scientific article

Prevalence of malaria parasites in adults and its determinants in malaria endemic area of Kisumu County, Kenya

scientific article published on 8 July 2015

Probable Post Traumatic Stress Disorder in Kenya and Its Associated Risk Factors: A Cross-Sectional Household Survey

scientific article

Prospective observational study to evaluate the clinical safety of the fixed-dose artemisinin-based combination Eurartesim® (dihydroartemisinin/piperaquine), in public health facilities in Burkina Faso, Mozambique, Ghana, and Tanzania

scientific article published on 15 April 2015

Provider compliance to artemisinin-based combination therapy at primary health care facilities in the middle belt of Ghana

scientific article

RTS,S malaria vaccine pilot studies: addressing the human realities in large-scale clinical trials.

scientific article

Results from tandem Phase 1 studies evaluating the safety, reactogenicity and immunogenicity of the vaccine candidate antigen Plasmodium falciparum FVO merozoite surface protein-1 (MSP1(42)) administered intramuscularly with adjuvant system AS01.

scientific article published on 23 January 2013

Risk reduction of diarrhea and respiratory infections following a community health education program - a facility-based case-control study in rural parts of Kenya

scientific article published on 29 April 2020

Safety and efficacy of the choline analogue SAR97276 for malaria treatment: results of two phase 2, open-label, multicenter trials in African patients

scientific article

Safety and immunogenicity of RTS,S/AS01 malaria vaccine in infants and children with WHO stage 1 or 2 HIV disease: a randomised, double-blind, controlled trial

scientific article published on 6 July 2016

Sample-ready multiplex qPCR assay for detection of malaria

scientific article

Seeking treatment for uncomplicated malaria: experiences from the Kintampo districts of Ghana

scientific article published on 20 February 2016

Similar efficacy and safety of artemether-lumefantrine (Coartem®) in African infants and children with uncomplicated falciparum malaria across different body weight ranges

scientific article published on 16 December 2011

Stabilization of RDT target antigens present in dried Plasmodium falciparum-infected samples for validating malaria rapid diagnostic tests at the point of care

scientific article published on 8 January 2018

Systematic comparison of two methods to measure parasite density from malaria blood smears

scientific article published on 30 March 2006

Tailoring a Pediatric Formulation of Artemether-Lumefantrine for Treatment of Plasmodium falciparum Malaria

scientific article published on 26 May 2015

Tedium vitae, death wishes, suicidal ideation and attempts in Kenya-prevalence and risk factors

scientific article published on 8 August 2015

The content of African diets is adequate to achieve optimal efficacy with fixed-dose artemether-lumefantrine: a review of the evidence

scientific article

The effect of dosing strategies on the therapeutic efficacy of artesunate-amodiaquine for uncomplicated malaria: a meta-analysis of individual patient data

scientific article published on 31 March 2015

The effect of food consumption on lumefantrine bioavailability in African children receiving artemether-lumefantrine crushed or dispersible tablets (Coartem) for acute uncomplicated Plasmodium falciparum malaria

scientific article published on 17 February 2010

The impact of clinical research activities on communities in rural Africa: the development of the Clinical Research Unit of Nanoro (CRUN) in Burkina Faso

scientific article

Towards an RTS,S-based, multi-stage, multi-antigen vaccine against falciparum malaria: progress at the Walter Reed Army Institute of Research.

scientific article

Towards harmonization of microscopy methods for malaria clinical research studies

scientific article published on 04 September 2020

Treatment of asymptomatic carriers with artemether-lumefantrine: an opportunity to reduce the burden of malaria?

scientific article

Treatment outcomes in a safety observational study of dihydroartemisinin/piperaquine (Eurartesim(®)) in the treatment of uncomplicated malaria at public health facilities in four African countries

scientific article published on 27 January 2016

True malaria prevalence in children under five: Bayesian estimation using data of malaria household surveys from three sub-Saharan countries

scientific article

Use of Antimalarial in the Management of Fever during a Community Survey in the Kintampo Districts of Ghana

scientific article published on 18 November 2015

Using health and demographic surveillance systems for teratovigilance in Africa

scientific article published in December 2016

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