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List of works by Annick Mühlethaler-Mottet

Activation of the MHC class II transactivator CIITA by interferon-gamma requires cooperative interaction between Stat1 and USF-1

scientific article published on 01 February 1998

Aldehyde dehydrogenase activity plays a Key role in the aggressive phenotype of neuroblastoma

scientific article

CIITA is a transcriptional coactivator that is recruited to MHC class II promoters by multiple synergistic interactions with an enhanceosome complex

scientific article

CIITA-induced occupation of MHC class II promoters is independent of the cooperative stabilization of the promoter-bound multi-protein complexes

scientific article published on 01 March 1999

Dendritic cells and differential usage of the MHC class II transactivator promoters in the central nervous system in experimental autoimmune encephalitis

scientific article published on 01 March 2000

Drug-mediated sensitization to TRAIL-induced apoptosis in caspase-8-complemented neuroblastoma cells proceeds via activation of intrinsic and extrinsic pathways and caspase-dependent cleavage of XIAP, Bcl-xL and RIP.

scientific article published on July 2004

Escape of human cytomegalovirus from HLA-DR-restricted CD4(+) T-cell response is mediated by repression of gamma interferon-induced class II transactivator expression

scientific article published on August 1999

Fenretinide-induced caspase-8 activation and apoptosis in an established model of metastatic neuroblastoma

scientific article

Functional sphere profiling reveals the complexity of neuroblastoma tumor-initiating cell model

scientific article

Histone deacetylase inhibitors strongly sensitise neuroblastoma cells to TRAIL-induced apoptosis by a caspases-dependent increase of the pro- to anti-apoptotic proteins ratio.

scientific article published on 24 August 2006

Individual caspase-10 isoforms play distinct and opposing roles in the initiation of death receptor-mediated tumour cell apoptosis. ⬇️

scientific article published on 3 March 2011

Involvement of the CXCR7/CXCR4/CXCL12 axis in the malignant progression of human neuroblastoma.

scientific article

Lessons from the bare lymphocyte syndrome: molecular mechanisms regulating MHC class II expression.

scientific article

Maturation of dendritic cells is accompanied by rapid transcriptional silencing of class II transactivator (CIITA) expression

scientific article

Molecular cytogenetic characterization of doxorubicin-resistant neuroblastoma cell lines: evidence that acquired multidrug resistance results from a unique large amplification of the 7q21 region

scientific article published on May 2006

Persistent inhibition of FLIP(L) expression by lentiviral small hairpin RNA delivery restores death-receptor-induced apoptosis in neuroblastoma cells.

scientific article published on February 2006

Restoration of TRAIL-induced apoptosis in a caspase-8-deficient neuroblastoma cell line by stable re-expression of caspase-8.

scientific article published on December 2003

TWIST1 expression is associated with high-risk neuroblastoma and promotes primary and metastatic tumor growth

scientific article published on 12 January 2022

The CXCR4/CXCR7/CXCL12 Axis Is Involved in a Secondary but Complex Control of Neuroblastoma Metastatic Cell Homing.

scientific article published on 8 May 2015

The S box of major histocompatibility complex class II promoters is a key determinant for recruitment of the transcriptional co-activator CIITA.

scientific article published on 22 July 2004

The Wnt receptor FZD1 mediates chemoresistance in neuroblastoma through activation of the Wnt/beta-catenin pathway

scientific article

The molecular basis of MHC class II deficiency and transcriptional control of MHC class II gene expression.

scientific article

Wild-type ALK and activating ALK-R1275Q and ALK-F1174L mutations upregulate Myc and initiate tumor formation in murine neural crest progenitor cells

scientific article

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