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List of works by Rudolf E Leube

3D segmentation of keratin intermediate filaments in confocal laser scanning microscopy.

scientific article

A keratin scaffold regulates epidermal barrier formation, mitochondrial lipid composition, and activity.

scientific article

A novel function for the MAP kinase SMA-5 in intestinal tube stability.

scientific article published on 12 October 2016

A rim-and-spoke hypothesis to explain the biomechanical roles for cytoplasmic intermediate filament networks

scientific article published in October 2017

Activation of the Silent Human Cytokeratin 17 Pseudogene‐Promoter Region by Cryptic Enhancer Elements of the Cytokeratin 17 Gene ⬇️

scientific article published on October 1, 1994

Cardiomyocyte Hypertrophy in Arrhythmogenic Cardiomyopathy

scientific article published on 6 February 2017

Characterization of the human gene encoding cytokeratin 17 and its expression pattern

scientific article published on October 1, 1992

Chromosomal assignments of human type I and type II cytokeratin genes to different chromosomes.

scientific article

Consequences of Keratin Phosphorylation for Cytoskeletal Organization and Epithelial Functions.

scientific article published on 6 December 2016

Contributions of cytoplasmic domains of desmosomal cadherins to desmosome assembly and intermediate filament anchorage ⬇️

scientific article published on February 26, 1993

Correction: A keratin scaffold regulates epidermal barrier formation, mitochondrial lipid composition, and activity

scientific article published on 21 March 2016

Daily oscillation of gene expression in the retina is phase-advanced with respect to the pineal gland

scientific journal article

Desmoglein 2 mutant mice develop cardiac fibrosis and dilation.

scientific article

Desmoglein 2 mutation provokes skeletal muscle actin expression and accumulation at intercalated discs in murine hearts

scientific article published on 18 February 2019

Desmoglein 2, but not desmocollin 2, protects intestinal epithelia from injury

scientific article published on 16 August 2018

Desmoglein 2-Dependent Arrhythmogenic Cardiomyopathy Is Caused by a Loss of Adhesive Function

scientific article

Desmoglein 2-mediated adhesion is required for intestinal epithelial barrier integrity.

scientific article

Desmosomal proteins: mediators of intercellular coupling and intermediate filament anchorage.

scientific article published on January 1992

Desmosome assembly and cell-cell adhesion are membrane raft-dependent processes.

scientific article published on 11 November 2010

Desmosomes: interconnected calcium-dependent structures of remarkable stability with significant integral membrane protein turnover.

scientific article published on April 2002

Detection of behavioral alterations and learning deficits in mice lacking synaptophysin.

scientific article

Dissection of keratin network formation, turnover and reorganization in living murine embryos

scientific article

Distinct Impact of Two Keratin Mutations Causing Epidermolysis Bullosa Simplex on Keratinocyte Adhesion and Stiffness.

scientific article published on 11 May 2015

Effects of Plectin Depletion on Keratin Network Dynamics and Organization.

scientific article

Epidermolysis bullosa simplex-type mutations alter the dynamics of the keratin cytoskeleton and reveal a contribution of actin to the transport of keratin subunits.

scientific article

Epithelial Intermediate Filaments: Guardians against Microbial Infection?

scientific article

Expression of keratins 1, 6, 15, 16, and 20 in normal cervical epithelium, squamous metaplasia, cervical intraepithelial neoplasia, and cervical carcinoma

scientific article published in February 1993

Expression of the synaptophysin gene family is not restricted to neuronal and neuroendocrine differentiation in rat and human

scientific article

Focal adhesions are hotspots for keratin filament precursor formation

scientific article

Hemidesmosomes and Focal Adhesions Treadmill as Separate but Linked Entities during Keratinocyte Migration

scientific article published on 02 April 2019

Human type I cytokeratin genes are a compact cluster.

scientific article

Identification of A Novel Link between the Intermediate Filament Organizer IFO-1 and Cholesterol Metabolism in the Caenorhabditis elegans Intestine

scientific article published on 03 November 2020

Identification of amino acid sequence motifs in desmocollin, a desmosomal glycoprotein, that are required for plakoglobin binding and plaque formation

scientific article

Identification of novel principles of keratin filament network turnover in living cells

scientific article

Induction of rapid and reversible cytokeratin filament network remodeling by inhibition of tyrosine phosphatases.

scientific article published in November 2002

Inflammation shapes pathogenesis of murine arrhythmogenic cardiomyopathy

scientific article published on 12 June 2020

Inkjet printed periodical micropatterns made of inert alumina ceramics induce contact guidance and stimulate osteogenic differentiation of mesenchymal stromal cells

scientific article

Interaction of human trophoblast cells with gland-like endometrial spheroids: a model system for trophoblast invasion

scientific article

Intermediate Filaments and Polarization in the Intestinal Epithelium

scientific article

Intermediate Filaments as Organizers of Cellular Space: How They Affect Mitochondrial Structure and Function

scientific article

Intermediate filaments and the regulation of focal adhesion.

scientific article

Intermediate filaments in Caenorhabditis elegans.

scientific article published on October 2009

Intestinal intermediate filament polypeptides in C. elegans: Common and isotype-specific contributions to intestinal ultrastructure and function

scientific article published on 21 February 2020

Intracellular Motility of Intermediate Filaments.

scientific article published on June 2017

Keratin 6a mutations lead to impaired mitochondrial quality control

scientific article published on 21 July 2019

Keratin dynamics: modeling the interplay between turnover and transport ⬇️

scientific article

Keratin intermediate filaments: intermediaries of epithelial cell migration

scientific article published on 01 October 2019

Keratins as the main component for the mechanical integrity of keratinocytes.

scientific article published on 28 October 2013

Light-induced resistance of the keratin network to the filament-disrupting tyrosine phosphatase inhibitor orthovanadate.

scientific article published in February 2003

Loss of desmoglein 2 suggests essential functions for early embryonic development and proliferation of embryonal stem cells

article

Loss of plakoglobin immunoreactivity in intercalated discs in arrhythmogenic right ventricular cardiomyopathy: protein mislocalization versus epitope masking

scientific article published on 16 December 2015

Maintenance of the intestinal tube in Caenorhabditis elegans: the role of the intermediate filament protein IFC-2.

scientific article published on 29 April 2008

Mechanical Probing of the Intermediate Filament-Rich Caenorhabditis Elegans Intestine

scientific article

Molecular dissection of desmosomal assembly and intermediate filament anchorage

scientific article published on 01 January 1998

Multidimensional Monitoring of Keratin Intermediate Filaments in Cultured Cells and Tissues

scientific article published on 03 November 2015

Periodic microstructures on bioactive glass surfaces enhance osteogenic differentiation of human mesenchymal stromal cells and promote osteoclastogenesis in vitro.

scientific article published on 22 March 2018

Placental vasculogenesis is regulated by keratin-mediated hyperoxia in murine decidual tissues

scientific article

Redistribution of adhering junctions in human endometrial epithelial cells during the implantation window of the menstrual cycle

scientific article published on 12 February 2012

Regulation of keratin network dynamics by the mechanical properties of the environment in migrating cells

scientific article published on 12 March 2020

Scratch-induced partial skin wounds re-epithelialize by sheets of independently migrating keratinocytes

scientific article published on 30 November 2020

Sex Matters: Interfering with the Oxidative Stress Response in Pachyonychia Congenita.

scientific article published in May 2018

SiRNA-mediated selective inhibition of mutant keratin mRNAs responsible for the skin disorder pachyonychia congenita

scientific article published on October 2006

Signal and noise modeling in confocal laser scanning fluorescence microscopy

scientific article published on 01 January 2012

Skin fragility and impaired desmosomal adhesion in mice lacking all keratins.

scientific article published on 11 October 2013

Sorting of synaptophysin into special vesicles in nonneuroendocrine epithelial cells

scientific article published on December 1994

Squamous cell metaplasia in the human lung: molecular characteristics of epithelial stratification.

scientific article published on January 1991

Structural and regulatory functions of keratins.

scientific article published on 15 March 2007

Synaptic tetraspan vesicle membrane proteins are conserved but not needed for synaptogenesis and neuronal function in Caenorhabditis elegans.

scholarly article

Synaptogyrin-dependent modulation of synaptic neurotransmission in Caenorhabditis elegans.

scientific article

Synaptophysin is required for synaptobrevin retrieval during synaptic vesicle endocytosis

scientific article

Synthesis of the mammalian synaptic vesicle protein synaptophysin in insect cells: a model for vesicle biogenesis.

scientific article published on April 1996

Tetraspan vesicle membrane proteins: synthesis, subcellular localization, and functional properties.

scientific article

The intestinal intermediate filament network responds to and protects against microbial insults and toxins

scientific article published on 23 January 2019

The keratin-desmosome scaffold: pivotal role of desmosomes for keratin network morphogenesis

scientific article published on 26 June 2019

The keratin-filament cycle of assembly and disassembly.

scientific article

The topogenic fate of the polytopic transmembrane proteins, synaptophysin and connexin, is determined by their membrane-spanning domains.

scientific article published on March 1995

The ubiquitin ligase CHIP/STUB1 targets mutant keratins for degradation.

scientific article

Threonine 150 phosphorylation of keratin 5 is linked to EBS and regulates filament assembly and cell viability

scientific article

Topogenesis and sorting of synaptophysin: Synthesis of a synaptic vesicle protein from a gene transfected into nonneuroendocrine cells

article

Transcriptional activation of psoriasis-associated cytokeratin K17 by interferon-gamma. Analysis of gamma-interferon activation sites.

scientific article published on January 1995

Transcriptome comparison of murine wild-type and synaptophysin-deficient retina reveals complete identity.

scientific article published on 7 March 2006

Ultrastructural changes in endometrial desmosomes of desmoglein 2 mutant mice

scientific article published on 25 June 2018

Visualization of gap junction mobility in living cells

scientific article published on 01 March 2000

p38 MAPK-dependent shaping of the keratin cytoskeleton in cultured cells.

scientific article

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