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Authors whose works are in public domain in at least one jurisdiction

List of works by Darryl C Zeldin

20-HETE Signals Through G-Protein-Coupled Receptor GPR75 (Gq) to Affect Vascular Function and Trigger Hypertension.

scientific article

A Slippery Cause of a Slimy Problem: Mucin Induction by an Esterified Lipid.

scientific article published in December 2017

A multi-center ring trial of allergen analysis using fluorescent multiplex array technology

journal article published in 2013

A novel genetic variant in PTGS1 affects N-glycosylation of cyclooxygenase-1 causing a dominant-negative effect

scientific article published on 16 December 2020

Abatement of cockroach allergen (Bla g 1) in low-income, urban housing: A randomized controlled trial.

scientific article published on August 2003

Abatement of cockroach allergens (Bla g 1 and Bla g 2) in low-income, urban housing: month 12 continuation results.

scientific article published on January 2004

Ablation of soluble epoxide hydrolase reprogram white fat to beige-like fat through an increase in mitochondrial integrity, HO-1-adiponectin in vitro and in vivo

scientific article published on 21 July 2018

Accentuated T helper type 2 airway response after allergen challenge in cyclooxygenase-1-/- but not cyclooxygenase-2-/- mice

scientific article published on 5 March 2003

Adeno-associated virus-mediated human C-reactive protein gene delivery causes endothelial dysfunction and hypertension in rats

scientific article published on 04 December 2008

Adenosine A2A receptor modulates vascular response in soluble epoxide hydrolase-null mice through CYP-epoxygenases and PPARγ

scientific article

Airway inflammation and responsiveness in prostaglandin H synthase-deficient mice exposed to bacterial lipopolysaccharide.

scientific article

Allergic lung responses are increased in prostaglandin H synthase-deficient mice.

scientific article

Allergy-related outcomes in relation to serum IgE: results from the National Health and Nutrition Examination Survey 2005-2006.

scientific article

Altered behavioral phenotypes in soluble epoxide hydrolase knockout mice: effects of traumatic brain injury

scientific article

Alternaria alternata antigens in US homes

scientific article published on 01 February 2006

An improved protocol for the treatment of fulminant myocarditis

scientific article published on 01 March 2019

Analysis of the cytotoxic properties of linoleic acid metabolites produced by renal and hepatic P450s

scientific article published on 01 November 2000

Anti-inflammatory properties of cytochrome P450 epoxygenase-derived eicosanoids.

scientific article

Antigenic stimulation with cytochrome P450 2J expressed in mouse hepatocellular carcinoma cells regulates host anti-tumour immunity.

scientific article published on 2 March 2009

Arachidonic acid epoxygenase metabolites stimulate endothelial cell growth and angiogenesis via mitogen-activated protein kinase and phosphatidylinositol 3-kinase/Akt signaling pathways

scientific article

Aspirin inhibits the production of proangiogenic 15(S)-HETE by platelet cyclooxygenase-1.

scientific article published on 15 September 2016

Association of childhood obesity with atopic and nonatopic asthma: results from the National Health and Nutrition Examination Survey 1999-2006.

scientific article

Association of common variants of CYP4A11 and CYP4F2 with stroke in the Han Chinese population

scientific article

Association of obesity with IgE levels and allergy symptoms in children and adolescents: results from the National Health and Nutrition Examination Survey 2005-2006.

scientific article published on 23 February 2009

Association of urinary levels of bisphenols F and S used as bisphenol A substitutes with asthma and hay fever outcomes

scientific article published on 22 November 2019

Associations Between Selected Xenobiotics and Antinuclear Antibodies in the National Health and Nutrition Examination Survey, 1999-2004

scientific article

Asthma cases attributable to atopy: results from the Third National Health and Nutrition Examination Survey

scientific article published on 24 September 2007

Author Correction: Epoxyeicosatrienoic acids enhance embryonic haematopoiesis and adult marrow engraftment

scientific article published on 01 September 2019

Basal and inducible anti-inflammatory epoxygenase activity in endothelial cells.

scientific article published on 13 March 2014

Bedroom Allergen Exposure Beyond House Dust Mites

scientific article published on 20 August 2018

Bedroom allergen exposures in US households.

scientific article published on 23 November 2017

Biochemical characterization of the human liver cytochrome P450 arachidonic acid epoxygenase pathway

scientific article published on 01 June 1996

Breast-feeding and the prevalence of asthma and wheeze in children: analyses from the Third National Health and Nutrition Examination Survey, 1988-1994.

scientific article published in February 2003

CREB mediates prostaglandin F2alpha-induced MUC5AC overexpression.

scientific article published on February 2009

CYP epoxygenase 2J2 prevents cardiac fibrosis by suppression of transmission of pro-inflammation from cardiomyocytes to macrophages.

scientific article published on January 2015

CYP2C40, a unique arachidonic acid 16-hydroxylase, is the major CYP2C in murine intestinal tract.

scientific article published in August 2000

CYP2C44, a new murine CYP2C that metabolizes arachidonic acid to unique stereospecific products.

scientific article published on 14 April 2004

CYP2J subfamily P450s in the lung: expression, localization, and potential functional significance

scientific article

CYP2J subfamily cytochrome P450s in the gastrointestinal tract: expression, localization, and potential functional significance

scientific article (publication date: June 1997)

CYP2J2 and CYP2C8 polymorphisms and coronary heart disease risk: the Atherosclerosis Risk in Communities (ARIC) study

scientific article

CYP2J2 attenuates metabolic dysfunction in diabetic mice by reducing hepatic inflammation via the PPARγ.

scientific article

CYP2J2 overexpression ameliorates hyperlipidemia via increased fatty acid oxidation mediated by the AMPK pathway.

scientific article

CYP2J2 overexpression attenuates nonalcoholic fatty liver disease induced by high-fat diet in mice

scientific article

CYP2J2 overexpression protects against arrhythmia susceptibility in cardiac hypertrophy

scientific article

CYP2J2 targeting to endothelial cells attenuates adiposity and vascular dysfunction in mice fed a high-fat diet by reprogramming adipocyte phenotype.

scientific article

CYP2J2-derived epoxyeicosatrienoic acids suppress endoplasmic reticulum stress in heart failure.

scientific article published on 21 October 2013

CYP450-derived oxylipins mediate inflammatory resolution.

scientific article published on 25 May 2016

CYP4F enzymes are the major enzymes in human liver microsomes that catalyze the O-demethylation of the antiparasitic prodrug DB289 [2,5-bis(4-amidinophenyl)furan-bis-O-methylamidoxime].

scientific article

Cardiac and vascular KATP channels in rats are activated by endogenous epoxyeicosatrienoic acids through different mechanisms

scientific article published on 22 June 2006

Cardiac-specific overexpression of CYP2J2 attenuates diabetic cardiomyopathy in male streptozotocin-induced diabetic mice

scientific article published on 21 May 2013

Cardiomyocyte-specific expression of CYP2J2 prevents development of cardiac remodelling induced by angiotensin II.

scientific article

Cats and dogs: an attractive remedy versus atopy?

scientific article published on 01 March 2010

Changes in Food-Specific IgE Over Time in the National Health and Nutrition Examination Survey (NHANES)

scientific article published on 22 April 2016

Characteristics of allergic sensitization among asthmatic adults older than 55 years: results from the National Health and Nutrition Examination Survey, 2005-2006.

scientific article published on 13 February 2013

Characterization of four new mouse cytochrome P450 enzymes of the CYP2J subfamily

scientific article published on 11 January 2013

Characterization of the Cytochrome P450 epoxyeicosanoid pathway in non-alcoholic steatohepatitis

scientific article published on 8 July 2016

Characterization of the Tissue Distribution of the Mouse Cyp2c Subfamily by Quantitative PCR Analysis.

scientific article

Cimetidine does not prevent lung injury in newborn premature infants.

scientific article published on 26 April 2006

Clinician agreement, self-efficacy, and adherence with the guidelines for the diagnosis and management of asthma

journal article published in 2018

Cloning and Expression of Murine CYP2Cs and Their Ability to Metabolize Arachidonic Acid ⬇️

scientific article published on September 1, 1998

Cloning of CYP2J2 gene and identification of functional polymorphisms

scientific article

Cloning, expression, and characterization of three new mouse cytochrome p450 enzymes and partial characterization of their fatty acid oxidation activities

scientific journal article

Cockroach allergen reduction by cockroach control alone in low-income urban homes: a randomized control trial

scientific article

Cockroach, dust mite, and shrimp sensitization correlations in the National Health and Nutrition Examination Survey

scientific article published on 23 February 2019

Commercial scale production of RvD4 opens the resolving door to new research

scientific article published on 30 March 2018

Comparison of cytochrome P450 (CYP) genes from the mouse and human genomes, including nomenclature recommendations for genes, pseudogenes and alternative-splice variants

scientific article

Comparison of enzyme immunoassay-based assays for environmental Alternaria alternata

scientific article published on September 2006

Conditional ablation of the RFX4 isoform 1 transcription factor: Allele dosage effects on brain phenotype.

scientific article published on 3 January 2018

Consortium-based science: the NIEHS's multipronged, collaborative approach to assessing the health effects of bisphenol A

scientific article

Contrasting effects of cyclooxygenase-1 (COX-1) and COX-2 deficiency on the host response to influenza A viral infection.

scientific article published in November 2005

Contribution of alveolar type II cell-derived cyclooxygenase-2 to basal airway function, lung inflammation, and lung fibrosis

scientific article

Correction to Optimized Inhibitors of Soluble Epoxide Hydrolase Improve in Vitro Target Residence Time and in Vivo Efficacy

scientific article

Cyclic AMP-induced changes in membrane conductance of Necturus gallbladder epithelial cells.

scientific article published in January 1985

Cyclooxygenase enzymes in allergic inflammation and asthma

scientific article

Cyclooxygenase polymorphisms and risk of cardiovascular events: the Atherosclerosis Risk in Communities (ARIC) study

scientific article

Cyclooxygenase-1 and -2 Knockout Mice Demonstrate Increased Cardiac Ischemia/Reperfusion Injury but Are Protected by Acute Preconditioning ⬇️

scientific article published on November 13, 2001

Cyclooxygenase-1 overexpression decreases Basal airway responsiveness but not allergic inflammation

scientific article

Cyclooxygenase-2 deficiency exacerbates bleomycin-induced lung dysfunction but not fibrosis

scientific article

Cyclooxygenase-2 inhibits T helper cell type 9 differentiation during allergic lung inflammation via down-regulation of IL-17RB.

scientific article published on April 2013

Cyclooxygenase-2 regulates Th17 cell differentiation during allergic lung inflammation

scientific article

Cyp2c44 epoxygenase in the collecting duct is essential for the high K+ intake-induced antihypertensive effect.

scientific article

Cyp2j5-Gene Deletion Affects on Acetylcholine and Adenosine-Induced Relaxation in Mice: Role of Angiotensin-II and CYP-Epoxygenase Inhibitor

scientific article published on 05 February 2020

Cytochrome P-450 epoxygenases protect endothelial cells from apoptosis induced by tumor necrosis factor-alpha via MAPK and PI3K/Akt signaling pathways.

scientific article

Cytochrome P450 (CYP) 2J2 gene transfection attenuates MMP-9 via inhibition of NF-kappabeta in hyperhomocysteinemia

scientific article published on June 2008

Cytochrome P450 2C8 ω3-long-chain polyunsaturated fatty acid metabolites increase mouse retinal pathologic neovascularization--brief report

scientific article published on 23 January 2014

Cytochrome P450 2J2 is highly expressed in hematologic malignant diseases and promotes tumor cell growth

scientific article

Cytochrome P450 2J2 is protective against global cerebral ischemia in transgenic mice

scientific article

Cytochrome P450 2J2 promotes the neoplastic phenotype of carcinoma cells and is up-regulated in human tumors

scientific article

Cytochrome P450 Oxidase 2C Inhibition Adds to ω-3 Long-Chain Polyunsaturated Fatty Acids Protection Against Retinal and Choroidal Neovascularization.

scientific article

Cytochrome P450 epoxygenase CYP2J2 attenuates nephropathy in streptozotocin-induced diabetic mice

scientific article published on 30 June 2011

Cytochrome P450 monooxygenase lipid metabolites are significant second messengers in the resolution of choroidal neovascularization

scientific article published on 21 August 2017

Cytochrome P450 pathways of arachidonic acid metabolism.

scientific article

Cytochrome P450-derived eicosanoids and vascular dysfunction in coronary artery disease patients

scientific article

Cytochrome P450-derived epoxyeicosatrienoic acids and coronary artery disease in humans: a targeted metabolomics study

scientific article

Cytochrome p450 epoxygenase promotes human cancer metastasis

scientific article

Decreased renal cytochrome P450 2C enzymes and impaired vasodilation are associated with angiotensin salt-sensitive hypertension.

scientific article published on 16 December 2002

Deficiency of Soluble Epoxide Hydrolase Protects Cardiac Function Impaired by LPS-Induced Acute Inflammation

scientific article published on 01 January 2018

Deletion of soluble epoxide hydrolase enhances coronary reactive hyperemia in isolated mouse heart: role of oxylipins and PPARγ

scientific article

Delivery of recombinant adeno-associated virus-mediated human tissue kallikrein for therapy of chronic renal failure in rats

scientific article published on April 2008

Design and synthesis of selective, high-affinity inhibitors of human cytochrome P450 2J2.

scientific article published on 21 February 2006

Detection of human CYP2C8, CYP2C9, and CYP2J2 in cardiovascular tissues

scientific article published on 12 January 2007

Differential effects of soluble epoxide hydrolase inhibition and CYP2J2 overexpression on postischemic cardiac function in aged mice.

scientific article published on 16 August 2012

Differential renal gene expression in prehypertensive and hypertensive spontaneously hypertensive rats.

scientific article published on 29 March 2005

Diminished acyl-CoA synthetase isoform 4 activity in INS 832/13 cells reduces cellular epoxyeicosatrienoic acid levels and results in impaired glucose-stimulated insulin secretion

scientific article published on 13 June 2013

Does exposure to cats and dogs decrease the risk of allergic sensitization and disease?

scientific article published on October 2009

Dog allergen (Can f 1) and cat allergen (Fel d 1) in US homes: results from the National Survey of Lead and Allergens in Housing.

scientific article published in July 2004

Dual modulation of cyclooxygenase and CYP epoxygenase metabolism and acute vascular inflammation in mice

scientific article published on 19 September 2012

Dust weight and asthma prevalence in the National Survey of Lead and Allergens in Housing (NSLAH).

scientific article published on 7 November 2006

Dustborne Alternaria alternata antigens in US homes: results from the National Survey of Lead and Allergens in Housing

scientific article published in September 2005

Dynamic expression of mucins and the genes controlling mucin-type O-glycosylation within the mouse respiratory system

scientific article published in 2023

E-018

EDHF function in the ductus arteriosus: evidence against involvement of epoxyeicosatrienoic acids and 12S-hydroxyeicosatetraenoic acid

scientific article

EET signaling in cancer

scientific article

EH3 (ABHD9): the first member of a new epoxide hydrolase family with high activity for fatty acid epoxides

scientific article published on 12 July 2012

Effect of Soluble Epoxide Hydrolase on the Modulation of Coronary Reactive Hyperemia: Role of Oxylipins and PPARγ

scientific article

Effects of physical interventions on house dust mite allergen levels in carpet, bed, and upholstery dust in low-income, urban homes

scientific article

Efficacy of an in-home test kit in reducing dust mite allergen levels: results of a randomized controlled pilot study

scientific article published on 26 August 2015

Eicosanoids and disease. Introduction

scientific article published on 08 October 2011

Electrophysiological properties of cardiomyocytes isolated from CYP2J2 transgenic mice

scientific article

Endogenous epoxygenases are modulators of monocyte/macrophage activity

scientific article

Endothelial CYP epoxygenase overexpression and soluble epoxide hydrolase disruption attenuate acute vascular inflammatory responses in mice

scientific article

Endothelial expression of human cytochrome P450 epoxygenase CYP2C8 increases susceptibility to ischemia-reperfusion injury in isolated mouse heart

scientific article

Endothelial expression of human cytochrome P450 epoxygenases lowers blood pressure and attenuates hypertension-induced renal injury in mice.

scientific article

Endotoxin Exposure: Predictors and Prevalence of Associated Asthma Outcomes in the United States

scientific article

Endotoxin clustering with allergens in house dust and asthma outcomes in a U.S. national study

scientific article published on 16 March 2020

Endotoxin exposure is a risk factor for asthma: the national survey of endotoxin in United States housing.

scientific article

Endotoxin predictors and associated respiratory outcomes differ with climate regions in the U.S.

scientific article published on 22 December 2017

Enhanced postischemic functional recovery in CYP2J2 transgenic hearts involves mitochondrial ATP-sensitive K+ channels and p42/p44 MAPK pathway

scientific article

Enhancement of cardiac L-type Ca2+ currents in transgenic mice with cardiac-specific overexpression of CYP2J2

scientific article

Environmental health research on hazards in the home and the duty to warn

scientific article published on May 2008

Environmental management of asthma in clinical practice: results from the 2012 National Ambulatory Medical Care Survey

journal article published in 2024

Ephx2-gene deletion affects acetylcholine-induced relaxation in angiotensin-II infused mice: role of nitric oxide and CYP-epoxygenases

scientific article published on 04 December 2019

Epoxide hydrolase 1 (EPHX1) hydrolyzes epoxyeicosanoids and impairs cardiac recovery after ischemia

scientific article published on 3 January 2018

Epoxide hydrolase 3 (Ephx3) gene disruption reduces ceramide linoleate epoxide hydrolysis and impairs skin barrier function

scientific article published on 17 December 2020

Epoxyeicosanoids as mediators of neurogenic vasodilation in cerebral vessels

scientific article

Epoxyeicosanoids promote organ and tissue regeneration.

scientific article published on 29 July 2013

Epoxyeicosanoids stimulate multiorgan metastasis and tumor dormancy escape in mice

scientific article published on 19 December 2011

Epoxyeicosatrienoic Acids Regulate Hematopoietic Stem/Progenitor Cell Fate Decision During Stress Response and Embryonic Hematopoiesis ⬇️

scholarly article

Epoxyeicosatrienoic acid agonist regulates human mesenchymal stem cell-derived adipocytes through activation of HO-1-pAKT signaling and a decrease in PPARγ

scientific article

Epoxyeicosatrienoic acids affect electrolyte transport in renal tubular epithelial cells: dependence on cyclooxygenase and cell polarity.

scientific article

Epoxyeicosatrienoic acids attenuate reactive oxygen species level, mitochondrial dysfunction, caspase activation, and apoptosis in carcinoma cells treated with arsenic trioxide

scientific article

Epoxyeicosatrienoic acids enhance embryonic haematopoiesis and adult marrow engraftment

scientific article

Epoxyeicosatrienoic acids protect rat hearts against tumor necrosis factor-α-induced injury

scientific article published on 5 January 2012

Epoxyeicosatrienoic acids regulate macrophage polarization and prevent LPS-induced cardiac dysfunction

scientific article published on September 2015

Epoxyeicosatrienoic and dihydroxyeicosatrienoic acids dilate human coronary arterioles via BK(Ca) channels: implications for soluble epoxide hydrolase inhibition

scientific article

Epoxygenase inactivation exacerbates diet and aging-associated metabolic dysfunction resulting from impaired adipogenesis.

scientific article

Epoxygenase metabolites of arachidonic acid affect electrophysiologic properties of rat tracheal epithelial cells1.

scientific article published in August 1998

Evaluation of cytochrome P450-derived eicosanoids in humans with stable atherosclerotic cardiovascular disease

scientific article

Excess nitric oxide decreases cytochrome P-450 2J4 content and P-450-dependent arachidonic acid metabolism in lungs of rats with acute pneumonia

scientific article published on 6 February 2004

Exposure and Sensitization to Pets Modify Endotoxin Association with Asthma and Wheeze

scientific article published on 20 April 2018

Exposure to Alternaria alternata in US homes is associated with asthma symptoms

scientific article published in October 2006

Exposure to indoor allergens in day-care facilities: results from 2 North Carolina counties

scientific article published in July 2005

Exposure to mouse allergen in U.S. homes associated with asthma symptoms

scientific article published on 06 October 2008

Exposure to multiple indoor allergens in US homes and its relationship to asthma

scientific article

Expression of Cyp2c/Cyp2j subfamily members and oxylipin levels during LPS-induced inflammation and resolution in mice

scientific article published on 05 November 2019

Feasibility of using subject-collected dust samples in epidemiologic and clinical studies of indoor allergens.

scientific article

Fenofibrate Inhibits Cytochrome P450 Epoxygenase 2C Activity to Suppress Pathological Ocular Angiogenesis

scientific article published on 30 September 2016

First National Survey of Lead and Allergens in Housing: survey design and methods for the allergen and endotoxin components.

scientific article

Functional characterization of cyclooxygenase-2 polymorphisms.

scientific article

Functional characterization of cytochrome P450-derived epoxyeicosatrienoic acids in adipogenesis and obesity

scientific article

Furin cleavage of the SARS-CoV-2 spike is modulated by O-glycosylation

Furin cleavage of the SARS-CoV-2 spike is modulated by O-glycosylation

scholarly article by Liping Zhang published in November 2021

G-protein pathway suppressor 2 (GPS2) interacts with the regulatory factor X4 variant 3 (RFX4_v3) and functions as a transcriptional co-activator

scientific journal article

Gender differences in murine airway responsiveness and lipopolysaccharide-induced inflammation

scientific article

Gene delivery of cytochrome p450 epoxygenase ameliorates monocrotaline-induced pulmonary artery hypertension in rats

scientific article

Gene therapy with human tissue kallikrein reduces hypertension and hyperinsulinemia in fructose-induced hypertensive rats.

scientific article published on 20 October 2003

Generation and characterization of epoxide hydrolase 3 (EPHX3)-deficient mice

scientific article

Genetic disruption of soluble epoxide hydrolase is protective against streptozotocin-induced diabetic nephropathy

scientific article published on 26 June 2012

Genetic variation in HTR4 and lung function: GWAS follow-up in mouse

scientific article published on 23 October 2014

Genetic variation in cytochrome P450 2J2 and soluble epoxide hydrolase and risk of ischemic stroke in a Chinese population

scientific article

Genetic variation in soluble epoxide hydrolase (EPHX2) and risk of coronary heart disease: the Atherosclerosis Risk in Communities (ARIC) study

journal article published in 2006

Genetic variation in soluble epoxide hydrolase (EPHX2) is associated with forearm vasodilator responses in humans

scientific article

Good or bad: Application of RAAS inhibitors in COVID-19 patients with cardiovascular comorbidities

scientific article published on 09 July 2020

Graded phenotypic response to partial and complete deficiency of a brain-specific transcript variant of the winged helix transcription factor RFX4

scientific journal article

High salt diet exacerbates vascular contraction in the absence of adenosine A₂A receptor

scientific article

High-salt diet enhances mouse aortic relaxation through adenosine A2A receptor via CYP epoxygenases

scientific article published on 24 December 2008

Higher Epoxyeicosatrienoic Acids in Cardiomyocytes-Specific CYP2J2 Transgenic Mice Are Associated with Improved Myocardial Remodeling

scientific article published on 30 May 2020

Hormonal influences on lung function and response to environmental agents: lessons from animal models of respiratory disease

scientific article published on December 2009

House Dust Endotoxin Association with Chronic Bronchitis and Emphysema.

scientific article published on 23 March 2018

House Dust Endotoxin and Peripheral Leukocyte Counts: Results from Two Large Epidemiologic Studies.

scientific article published on 31 May 2017

House dust mite allergen in US beds: results from the First National Survey of Lead and Allergens in Housing

scientific article published in February 2003

Housing interventions and control of asthma-related indoor biologic agents: a review of the evidence

scientific article

How exposures to biologics influence the induction and incidence of asthma

scientific article

Human enteric microsomal CYP4F enzymes O-demethylate the antiparasitic prodrug pafuramidine

scientific article published on 20 August 2007

Hydrogen peroxide inhibits cytochrome p450 epoxygenases: interaction between two endothelium-derived hyperpolarizing factors

scientific article published on November 2007

Identification and functional characterization of polymorphisms in human cyclooxygenase-1 (PTGS1).

scientific article

Identification and regulation of a new vertebrate cytochrome P450 subfamily, the CYP2Ps, and functional characterization of CYP2P3, a conserved arachidonic acid epoxygenase/19-hydroxylase.

scientific article published in March 2003

Identification of a homozygous recessive variant in PTGS1 resulting in a congenital aspirin-like defect in platelet function

scientific article published on 16 April 2020

Identification of potential target genes for RFX4_v3, a transcription factor critical for brain development

scientific article

Immunochemical detection of cytochrome P450 enzymes in liver microsomes of 27 cynomolgus monkeys.

scientific article

Immunochemical detection of cytochrome P450 enzymes in small intestine microsomes of male and female untreated juvenile cynomolgus monkeys

scientific article

Immunochemical quantification of cynomolgus CYP2J2, CYP4A and CYP4F enzymes in liver and small intestine.

scientific article

Increased CYP2J expression and epoxyeicosatrienoic acid formation in spontaneously hypertensive rat kidney.

scientific article published on May 2000

Increased CYP2J3 expression reduces insulin resistance in fructose-treated rats and db/db mice

scientific article

Increased blood pressure in mice lacking cytochrome P450 2J5

scientific journal article

Increased endothelial nitric-oxide synthase expression reduces hypertension and hyperinsulinemia in fructose-treated rats ⬇️

scientific article

Increasing Prevalence of Antinuclear Antibodies in the United States

scientific article published on 07 April 2020

Indapamide lowers blood pressure by increasing production of epoxyeicosatrienoic acids in the kidney.

scientific article published on 31 May 2013

Indoor allergens in school and day care environments

scientific article published on 03 July 2009

Indoor determinants of dustborne allergens in Mexican homes

scientific article published in 2015

Inducible CYP2J2 and its product 11,12-EET promotes bacterial phagocytosis: a role for CYP2J2 deficiency in the pathogenesis of Crohn's disease?

scientific article

Induction of cardiac cytochrome p450 in cocaine-treated mice

scientific article published in March 2002

Inhaled nitric oxide attenuates hyperoxic lung injury in lambs.

scientific article published on 2 December 2005

Inherited human group IVA cytosolic phospholipase A2 deficiency abolishes platelet, endothelial, and leucocyte eicosanoid generation.

scientific article

Inhibition of cardiac L-type calcium channels by epoxyeicosatrienoic acids

scientific article published on 01 February 1999

Inhibition of vascular smooth muscle cell migration by cytochrome p450 epoxygenase-derived eicosanoids

scientific article

Inner-City Environments and Mitigation of Cockroach Allergen

scientific article published on 01 August 2011

Intimal smooth muscle cells are a source but not a sensor of anti-inflammatory CYP450 derived oxylipins

scientific article

Introduction

scientific article published on 01 January 2019

It All Begins In Utero: Cord Blood Bacterial DNA and T Cell Immunity

scientific article published in October 2017

It's all about sex: gender, lung development and lung disease

scientific article published on 30 August 2007

Kidney Transplantation in a Patient Lacking Cytosolic Phospholipase A2 Proves Renal Origins of Urinary PGI-M and TX-M.

scientific article published on 3 January 2018

Letter by Mitchell et al Regarding Article, "Urinary Prostaglandin Metabolites: An Incomplete Reckoning and a Flush to Judgment"

scientific article published on 01 May 2018

Lipopolysaccharide Potentiates Insulin-Driven Hypoglycemic Shock.

scientific article published on 16 October 2017

Lrp1 Regulation of Pulmonary Function: Follow-up of Human GWAS in Mouse

scientific article published on 08 December 2020

Male sex hormones exacerbate lung function impairment after bleomycin-induced pulmonary fibrosis

scientific article published on 14 February 2008

Male sex hormones promote vagally mediated reflex airway responsiveness to cholinergic stimulation

scientific article

Mapping of the CYP2J cytochrome P450 genes to human chromosome 1 and mouse chromosome 4

scientific article

Mechanistic definition of the cardiovascular mPGES-1/COX-2/ADMA axis

scientific article published on 05 November 2019

Metabolic reprogramming through fatty acid transport protein 1 (FATP1) regulates macrophage inflammatory potential and adipose inflammation

scientific article published on 23 April 2016

Midazolam metabolism in cytochrome P450 3A knockout mice can be attributed to up-regulated CYP2C enzymes

scientific article published on 21 December 2007

Mite-impermeable bedding casings and severe asthma exacerbations

scientific article published in January 2018

Modulation by salt intake of the vascular response mediated through adenosine A(2A) receptor: role of CYP epoxygenase and soluble epoxide hydrolase.

scientific article

Modulation of allergic airway inflammation by the oral pathogen Porphyromonas gingivalis

scientific article

Molecular cloning and characterization of mouse CYP2J6, an unstable cytochrome P450 isoform

scientific article

Molecular cloning, enzymatic characterization, developmental expression, and cellular localization of a mouse cytochrome P450 highly expressed in kidney.

scientific article

Molecular cloning, expression and characterization of an endogenous human cytochrome P450 arachidonic acid epoxygenase isoform

scientific article

Molecular cloning, expression, and functional significance of a cytochrome P450 highly expressed in rat heart myocytes.

scientific article published on May 1997

NIAID, NIEHS, NHLBI, and MCAN workshop report: the indoor environment and childhood asthma - implications for home environmental intervention in asthma prevention and management

journal article published in 2017

NIEHS: Making a Mark on Translational Research Science

scientific article published on 02 August 2018

NOS3 polymorphisms, cigarette smoking, and cardiovascular disease risk: the Atherosclerosis Risk in Communities study

scientific article

Nanoparticle-mediated drug delivery and pulmonary hypertension

scientific article published on 23 March 2009

National prevalence and exposure risk for cockroach allergen in U.S. households

scientific article

National prevalence and exposure risk for mouse allergen in US households

scientific article

National prevalence and risk factors for food allergy and relationship to asthma: results from the National Health and Nutrition Examination Survey 2005-2006.

scientific article

Nitrogen dioxide and allergic sensitization in the 2005-2006 National Health and Nutrition Examination Survey

scientific article published on 28 August 2013

Novel relationship of serum cholesterol with asthma and wheeze in the United States.

scientific article published on 03 October 2009

Nutritional status modulates rat liver cytochrome P450 arachidonic acid metabolism.

scientific article published in September 1998

O-013

Optimized inhibitors of soluble epoxide hydrolase improve in vitro target residence time and in vivo efficacy

scientific article

Oral pathogens and allergic disease: results from the Third National Health and Nutrition Examination Survey.

scientific article

Overexpression of CYP2J2 provides protection against doxorubicin-induced cardiotoxicity

scientific article published on 08 May 2009

Overexpression of cytochrome P450 epoxygenases prevents development of hypertension in spontaneously hypertensive rats by enhancing atrial natriuretic peptide.

scientific article

Oxidation of benzo[a]pyrene by recombinant human cytochrome P450 enzymes

scientific article published on 01 January 1995

O‐glycosylation of the novel SARS‐CoV‐2 coronavirus spike protein influences furin cleavage

scientific article

PGE2 Inhibits IL-10 Production via EP2-Mediated β-Arrestin Signaling in Neuroinflammatory Condition

scientific article

Pharmacologic inhibition of COX-1 and COX-2 in influenza A viral infection in mice.

scientific article

Phl p 4: An early indicator of grass pollen allergy?

scientific article published on 01 June 2020

Phthalate exposure and allergy in the U.S. population: results from NHANES 2005-2006

scientific article published in October 2013

Plasma 15-Hydroxyeicosatetraenoic Acid Predicts Treatment Outcomes in Aspirin-Exacerbated Respiratory Disease.

scientific article published on 29 December 2016

Plasticity of cytochrome P450 isozyme expression in rat trigeminal ganglia neurons during inflammation

scientific article

Podocyte-specific soluble epoxide hydrolase deficiency in mice attenuates acute kidney injury.

scientific article published on 9 May 2017

Polymorphisms in human CYP2C8 decrease metabolism of the anticancer drug paclitaxel and arachidonic acid.

scientific article

Polymorphisms in human soluble epoxide hydrolase.

scientific article published in August 2003

Polymorphisms in the transcription factor NRF2 and forearm vasodilator responses in humans.

scientific article published on August 2012

Pre-diagnostic serum levels of fatty acid metabolites and risk of ovarian cancer in the Prostate, Lung, Colorectal, and Ovarian Cancer (PLCO) Screening Trial

scientific article published on 27 September 2018

Predictors of endotoxin levels in U.S. housing

scientific article

Predictors of upstream inflammation and oxidative stress pathways during early pregnancy

scholarly article published in March 2024

Predominant expression of an arachidonate epoxygenase in islets of Langerhans cells in human and rat pancreas

scientific article

Prevalence and sociodemographic correlates of antinuclear antibodies in the United States

scientific article published in July 2012

Prevalence of allergic sensitization in the United States: results from the National Health and Nutrition Examination Survey (NHANES) 2005-2006.

scientific article

Prevalences of positive skin test responses to 10 common allergens in the US population: results from the third National Health and Nutrition Examination Survey

scientific article published in August 2005

Primary care clinician adherence with asthma guidelines: the National Asthma Survey of Physicians

journal article published in 2020

Proficiency testing of allergen measurements in residential dust

scientific article published on 01 October 2005

Profiling the eicosanoid networks that underlie the anti- and pro-thrombotic effects of aspirin

scientific article published on 27 June 2020

Prostaglandin E₂ protects murine lungs from bleomycin-induced pulmonary fibrosis and lung dysfunction

scientific article published on 19 August 2011

Prostaglandin-E2 counteracts interleukin-1beta-stimulated upregulation of platelet-derived growth factor alpha-receptor on rat pulmonary myofibroblasts

scientific article published on 01 March 1999

Prostaglandins and Other Lipid Mediators (POLM), Special Issue of the 6th European workshop on lipid mediators: Role of Müller cell cytochrome P450 2c44 in murine retinal angiogenesis.

scientific article published on 22 April 2017

Protective actions of epoxyeicosatrienoic acid: dual targeting of cardiovascular PI3K and KATP channels

scientific article

Pulmonary applications and toxicity of engineered nanoparticles

scientific article

Pulmonary cytochrome P-450 2J4 is reduced in a rat model of acute Pseudomonas pneumonia

scientific journal article

Quantitative Polymerase Chain Reaction Analysis of the Mouse Cyp2j Subfamily: Tissue Distribution and Regulation

scientific article published on 20 May 2015

Questionnaire predictors of atopy in a US population sample: findings from the National Health and Nutrition Examination Survey, 2005-2006

scientific article published in March 2011

Rabbit aorta converts 15-HPETE to trihydroxyeicosatrienoic acids: potential role of cytochrome P450.

scientific article published in December 2003

Racial/ethnic and socioeconomic differences in self-reported food allergy among food-sensitized children in National Health and Nutrition Examination Survey III.

scientific article published on 24 October 2016

Reduced coronary reactive hyperemia in mice was reversed by the soluble epoxide hydrolase inhibitor (t-AUCB): Role of adenosine A2A receptor and plasma oxylipins.

scientific article published on 7 September 2017

Regio- and enantiofacial selectivity of epoxyeicosatrienoic acid hydration by cytosolic epoxide hydrolase

scientific article published on 01 March 1993

Regulation of T helper cell subsets by cyclooxygenases and their metabolites

scientific article

Regulation of mouse renal CYP2J5 expression by sex hormones

scientific article published in March 2004

Regulatory factor X4 variant 3: a transcription factor involved in brain development and disease

scientific article published on December 2007

Relation between objective measures of atopy and myocardial infarction in the United States

scientific article

Relationship between serum cholesterol and indices of erythrocytes and platelets in the US population

scientific article published on 02 September 2013

Relationship of serum cholesterol levels to atopy in the US population

scientific article

Reply: To PMID 22921873.

scientific article published on 30 April 2013

Reply: cytochrome P450-derived eicosanoids and the vascular wall

scientific article published on 01 April 2000

Reproductive and hormonal risk factors for antinuclear antibodies (ANA) in a representative sample of U.S. women

scientific article

Research on environmental health interventions: ethical problems and solutions

scientific article published on April 2005

Resolution of dihydroxyeicosanoates and of dihydroxyeicosatrienoates by chiral phase chromatography

scientific article published on December 1, 1992

Resolvin Infectious Inflammation by Targeting the Host Response

scientific article

Respiratory disease in United States farmers

journal article published in 2014

Risk of coronary artery disease associated with polymorphism of the cytochrome P450 epoxygenase CYP2J2

scientific article

Role of Arginine 117 in Substrate Recognition by Human Cytochrome P450 2J2

scholarly article by Pierre Lafite published in July 2018

Role of B-type natriuretic peptide in epoxyeicosatrienoic acid-mediated improved post-ischaemic recovery of heart contractile function.

scientific article published on 28 April 2009

Role of CYP epoxygenases in A2A AR-mediated relaxation using A2A AR-null and wild-type mice

scientific article published on 19 September 2008

Role of caveolae in shear stress-mediated endothelium-dependent dilation in coronary arteries

scientific article

Role of cyclooxygenase-2 in exacerbation of allergen-induced airway remodeling by multiwalled carbon nanotubes.

scientific article published on October 2013

Role of endothelial soluble epoxide hydrolase in cerebrovascular function and ischemic injury.

scientific article

Role of epoxyeicosatrienoic acids in protecting the myocardium following ischemia/reperfusion injury

scientific article

Role of linoleic acid-derived oxylipins in cancer

scientific article published on 04 July 2020

Role of soluble epoxide hydrolase in postischemic recovery of heart contractile function

scientific article

Role of ω-hydroxylase in adenosine-mediated aortic response through MAP kinase using A2A-receptor knockout mice

scientific article published on 7 December 2011

Roles of the epoxygenase CYP2J2 in the endothelium.

scientific article published on 06 March 2013

Rosuvastatin attenuates the elevation in blood pressure induced by overexpression of human C-reactive protein.

scientific article

Salt modulates vascular response through adenosine A(2A) receptor in eNOS-null mice: role of CYP450 epoxygenase and soluble epoxide hydrolase.

scientific article published on 14 December 2010

Salt-sensitive hypertension after exposure to angiotensin is associated with inability to upregulate renal epoxygenases

scientific article published on 04 August 2003

Selective inhibitors of CYP2J2 related to terfenadine exhibit strong activity against human cancers in vitro and in vivo

scientific article (publication date: June 2009)

Selective, competitive and mechanism-based inhibitors of human cytochrome P450 2J2.

scientific article published on 10 April 2007

Sensitization and Exposure to Pets: The Effect on Asthma Morbidity in the US Population.

scientific article published on 07 July 2017

Severely blunted allergen-induced pulmonary Th2 cell response and lung hyperresponsiveness in type 1 transient receptor potential channel-deficient mice.

scientific article

Sex- and isoform-specific mechanism of neuroprotection by transgenic expression of P450 epoxygenase in vascular endothelium

scientific article

Single nucleotide polymorphisms in the CYP2J2 and CYP2C8 genes and the risk of hypertension

scientific article

Sinus Surgery Is Associated with a Decrease in Aspirin-Induced Reaction Severity in Patients with Aspirin Exacerbated Respiratory Disease

scientific article published on 21 December 2018

Slower skeletal muscle phenotypes are critical for constitutive expression of Hsp70 in overloaded rat plantaris muscle.

scientific article

Soluble Epoxide Hydrolase Inhibition by t-TUCB Promotes Brown Adipogenesis and Reduces Serum Triglycerides in Diet-Induced Obesity

scientific article published on 24 September 2020

Soluble epoxide hydrolase deficiency attenuates lipotoxic cardiomyopathy via upregulation of AMPK-mTORC mediated autophagy

scientific article published on 27 December 2020

Soluble epoxide hydrolase in podocytes is a significant contributor to renal function under hyperglycemia.

scientific article

Soluble epoxide hydrolase null mice exhibit female and male differences in regulation of vascular homeostasis

scientific article

Spina Bifida

Spontaneous airway hyperresponsiveness in estrogen receptor-alpha-deficient mice

scientific article published on 9 November 2006

Susceptibility of cyclooxygenase-2-deficient mice to pulmonary fibrogenesis

scientific article published on August 2002

Synergistic Association of House Endotoxin Exposure and Ambient Air Pollution with Asthma Outcomes

scientific article published on 01 September 2019

Targeted Metabolomics Identifies the Cytochrome P450 Monooxygenase Eicosanoid Pathway as a Novel Therapeutic Target of Colon Tumorigenesis

scientific article published on 25 February 2019

The 5-lipoxygenase pathway: a new therapeutic target for the treatment of pulmonary fibrosis

scientific article published in January 2002

The Distinguished Legacy of Linda S. Birnbaum, an Environmental Health Champion

scientific article published on 22 October 2019

The Environmental Polymorphism Registry: a unique resource that facilitates translational research of environmental disease

scientific article published on 9 June 2011

The Prevalence of Lead-Based Paint Hazards in U.S. Housing

scientific article

The Role of Cytochrome P450 Epoxygenases, Soluble Epoxide Hydrolase, and Epoxyeicosatrienoic Acids in Metabolic Diseases

scientific article published on 15 November 2016

The Toll-like receptor 5 ligand flagellin promotes asthma by priming allergic responses to indoor allergens

scientific article

The cytochrome P450 epoxygenase pathway regulates the hepatic inflammatory response in fatty liver disease.

scientific article

The epoxyeicosatrienoic acid-stimulated phosphorylation of EGF-R involves the activation of metalloproteinases and the release of HB-EGF in cancer cells

scientific article published on February 2010

The epoxygenases CYP2J2 activates the nuclear receptor PPARalpha in vitro and in vivo

scientific article

The human intestinal cytochrome P450 "pie".

scientific article

The impact of sex and sex hormones on lung physiology and disease: lessons from animal studies

scientific article

The nuclear receptors constitutive active/androstane receptor and pregnane x receptor activate the Cyp2c55 gene in mouse liver.

scientific article

The rabbit pulmonary cytochrome P450 arachidonic acid metabolic pathway: characterization and significance.

scientific article

The reality of pharmacogenomics: optimizing therapeutic decision making

scientific article

The soluble epoxide hydrolase gene harbors sequence variation associated with susceptibility to and protection from incident ischemic stroke

scientific article

Tissue kallikrein reverses insulin resistance and attenuates nephropathy in diabetic rats by activation of phosphatidylinositol 3-kinase/protein kinase B and adenosine 5'-monophosphate-activated protein kinase signaling pathways

scientific article

Total IgE levels and asthma prevalence in the US population: results from the National Health and Nutrition Examination Survey 2005-2006.

scientific article published on 03 August 2009

Transethnic associations among immune-mediated diseases and single-nucleotide polymorphisms of the aryl hydrocarbon response gene ARNT and the PTPN22 immune regulatory gene

scientific article published on 21 November 2019

Tristetraprolin (TTP) coordinately regulates primary and secondary cellular responses to proinflammatory stimuli

scientific article

Unusual regioselectivity and active site topology of human cytochrome P450 2J2

scientific article published on 17 August 2007

Up-regulation of endothelial nitric-oxide synthase by endothelium-derived hyperpolarizing factor involves mitogen-activated protein kinase and protein kinase C signaling pathways.

scientific article published on 15 September 2003

Use of national asthma guidelines by allergists and pulmonologists: a national survey

journal article published in 2020

Vagal innervation is required for pulmonary function phenotype in Htr4-/- mice

scientific article published on 27 January 2017

Validation of Questionnaire-based Case Definitions for Chronic Obstructive Pulmonary Disease

scientific article published on 04 February 2020

Variability of CYP2J2 expression in human fetal tissues

scientific article published on 25 July 2006

Vascular Lipidomic Profiling of Potential Endogenous Fatty Acid PPAR Ligands Reveals the Coronary Artery as Major Producer of CYP450-Derived Epoxy Fatty Acids

scientific article published on 29 April 2020

Vascular actions of 20-HETE

scientific article

Vascular characterization of mice with endothelial expression of cytochrome P450 4F2.

scientific article

Vascular endothelial over-expression of soluble epoxide hydrolase (Tie2-sEH) enhances adenosine A1 receptor-dependent contraction in mouse mesenteric arteries: role of ATP-sensitive K+ channels.

scientific article

Vascular endothelial overexpression of human CYP2J2 (Tie2-CYP2J2 Tr) modulates cardiac oxylipin profiles and enhances coronary reactive hyperemia in mice.

scientific article

Ventilation defects observed with hyperpolarized 3He magnetic resonance imaging in a mouse model of acute lung injury

scientific article

Vitamin C activation of the biosynthesis of epoxyeicosatrienoic acids

scientific article published on June 2012

WEC 2016 special issue editorial.

scientific article published on 16 September 2017

β-Arrestin-2 deficiency attenuates abdominal aortic aneurysm formation in mice

scientific article

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