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List of works by Philippe Rondard

A comparative phenotypic study of kallmann syndrome patients carrying monoallelic and biallelic mutations in the prokineticin 2 or prokineticin receptor 2 genes

scientific article published on 18 December 2009

A mutational approach shows similar mechanisms of recognition for the isolated and integrated versions of a protein epitope

scientific article published on 01 December 1998

A new approach to analyze cell surface protein complexes reveals specific heterodimeric metabotropic glutamate receptors.

scientific article published on 8 September 2010

A new family of receptor tyrosine kinases with a venus flytrap binding domain in insects and other invertebrates activated by aminoacids

scientific article

Activation of a dimeric metabotropic glutamate receptor by intersubunit rearrangement.

scientific article published on 13 September 2007

Allosteric control of an asymmetric transduction in a G protein-coupled receptor heterodimer.

scientific article

Allosteric functioning of dimeric class C G-protein-coupled receptors.

scientific article

Allosteric modulators enhance agonist efficacy by increasing the residence time of a GPCR in the active state

scientific article published on 14 September 2021

Allosteric nanobodies uncover a role of hippocampal mGlu2 receptor homodimers in contextual fear consolidation.

scientific article published on 6 December 2017

Biased signaling through G-protein-coupled PROKR2 receptors harboring missense mutations

scientific article published on 15 May 2014

Cell-surface protein-protein interaction analysis with time-resolved FRET and snap-tag technologies: application to G protein-coupled receptor oligomerization

scientific article published on January 1, 2011

Complex GABAB receptor complexes: how to generate multiple functionally distinct units from a single receptor.

scientific article published on 11 February 2014

Conformational and Functional Properties of an Undecapeptide Epitope Fused with the C-Terminal End of the Maltose Binding Protein ⬇️

scientific article (publication date: 22 July 1997)

Coupling of agonist binding to effector domain activation in metabotropic glutamate-like receptors

scientific article published on 20 June 2006

Dimers and beyond: The functional puzzles of class C GPCRs.

scientific article published on 20 January 2011

Distinct roles of metabotropic glutamate receptor dimerization in agonist activation and G-protein coupling ⬇️

scientific article published on September 17, 2012

Dominant role of GABAB2 and Gbetagamma for GABAB receptor-mediated-ERK1/2/CREB pathway in cerebellar neurons.

scientific article

Dynamics and modulation of metabotropic glutamate receptors.

scientific article published on 17 December 2014

FRET-Based Sensors Unravel Activation and Allosteric Modulation of the GABAB Receptor

scientific article published on 6 March 2017

Fine tuning of sub-millisecond conformational dynamics controls metabotropic glutamate receptors agonist efficacy

scientific article published in Nature Communications

Functioning of the dimeric GABA(B) receptor extracellular domain revealed by glycan wedge scanning.

scientific article published on 3 April 2008

G-protein-coupled receptor oligomers: two or more for what? Lessons from mGlu and GABAB receptors.

scientific article published on September 2009

GABAB receptor activation protects neurons from apoptosis via IGF-1 receptor transactivation.

scientific article published in January 2010

GABAB receptor upregulates fragile X mental retardation protein expression in neurons

scientific article published on 28 May 2015

HTS-compatible FRET-based conformational sensors clarify membrane receptor activation.

scientific article published on 30 January 2017

Illuminating the activation mechanisms and allosteric properties of metabotropic glutamate receptors

scientific article published on 4 March 2013

Illuminating the allosteric modulation of the calcium-sensing receptor

scientific article published on 19 August 2020

Interdomain movements in metabotropic glutamate receptor activation ⬇️

scientific article published on September 6, 2011

Major ligand-induced rearrangement of the heptahelical domain interface in a GPCR dimer.

scientific article published on 15 December 2014

Molecular determinants involved in the allosteric control of agonist affinity in the GABAB receptor by the GABAB2 subunit.

scientific article published on 21 January 2004

Mutant G protein alpha subunit activated by Gbeta gamma: a model for receptor activation?

scientific article

Mutational analysis of an antigenic peptide shows recognition in a loop conformation.

scientific article published on July 1997

Oligomerization of a G protein-coupled receptor in neurons controlled by its structural dynamics.

scientific article published on 10 July 2018

PROK2/PROKR2 Signaling and Kallmann Syndrome.

scientific article published on 12 April 2013

PROKR2 missense mutations associated with Kallmann syndrome impair receptor signalling activity

scientific article

PROKR2 variants in multiple hypopituitarism with pituitary stalk interruption.

scientific article published on 30 March 2012

Pharmacological evidence for a metabotropic glutamate receptor heterodimer in neuronal cells

scientific article

Rearrangement of the transmembrane domain interfaces associated with the activation of a GPCR hetero-oligomer

scientific article published on 24 June 2019

Structural basis of the activation of a metabotropic GABA receptor

scientific article published on 17 June 2020

Targeting the Brain with Single-Domain Antibodies: Greater Potential Than Stated So Far?

scientific article published in 2023

Trans-activation between 7TM domains: implication in heterodimeric GABABreceptor activation ⬇️

scientific article published on November 9, 2010

Variations in PROKR2, but not PROK2, are associated with hypopituitarism and septo-optic dysplasia.

scientific article published on 5 February 2013

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