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List of works by Robert Heyderman

837Early Goal Directed Therapy for Acute Bacterial Meningitis in Malawian Adults.

scientific article

845Prediction of Outcome from Adult Bacterial Meningitis in a High HIV Seroprevelence, Resource-Poor Setting Using a New Severity Scoring Tool, the Malawi Adult Meningitis Score (MAMS).

scientific article published in December 2014

A Perspective on Invasive Salmonella Disease in Africa

scientific article published in November 2015

A microfluidic system to study cytoadhesion of Plasmodium falciparum infected erythrocytes to primary brain microvascularendothelial cells

scientific article

A prospective longitudinal study of the clinical outcomes from cryptococcal meningitis following treatment induction with 800 mg oral fluconazole in Blantyre, Malawi

scientific article (publication date: 2013)

A prospective study of mortality from cryptococcal meningitis following treatment induction with 1200 mg oral fluconazole in Blantyre, Malawi

scientific article

A reduction in adult blood stream infection and case fatality at a large African hospital following antiretroviral therapy roll-out

scientific article published on 18 March 2014

Absence of mucosal immunity in the human upper respiratory tract to the commensal bacteria Neisseria lactamica but not pathogenic Neisseria meningitidis during the peak age of nasopharyngeal carriage.

scientific article

Acquisition of pneumococci specific effector and regulatory Cd4+ T cells localising within human upper respiratory-tract mucosal lymphoid tissue.

scientific article published on December 2011

Acute bacterial meningitis in adults

scientific article published on 2 June 2016

Addition of flucytosine to fluconazole for the treatment of cryptococcal meningitis in Africa: a multi-country cost-effectiveness analysis

scientific article published on 01 January 2020

Adjunctive Dexamethasone in HIV-Associated Cryptococcal Meningitis

scientific article published in February 2016

Adults with cerebral malaria do not have sensory evoked responses typical of deep general anaesthesia.

scientific article published on March 2000

Aetiology and Risk Factors for Mortality in an Adult Community-Acquired Pneumonia Cohort in Malawi

scientific article published on 9 January 2019

Age Related Patterns of Disease and Mortality in Hospitalised Adults in Malawi

scientific article published on 18 January 2017

Alteration in glycosaminoglycan metabolism and surface charge on human umbilical vein endothelial cells induced by cytokines, endotoxin and neutrophils

scientific article published on August 1, 1992

Alveolar T-helper 17 responses to streptococcus pneumoniae are preserved in ART-untreated and treated HIV-infected Malawian adults

scientific article published on 29 November 2017

Analysis of pathogen-host cell interactions in purpura fulminans: expression of capsule, type IV pili, and PorA by Neisseria meningitidis in vivo.

scientific article published in September 2002

Antibiotic choices for meningitis beyond the neonatal period ⬇️

scientific article published on February 1, 1992

Antibiotic treatment of suspected neonatal meningitis.

scientific article published on January 1991

Antibody imaging to locate a placental site trophoblastic tumour following a complete hydatidiform mole

scientific article published on 01 May 1989

Antifungal Combinations for Treatment of Cryptococcal Meningitis in Africa.

scientific article published in March 2018

Arterial ischemic stroke in HIV: Defining and classifying etiology for research studies

scientific article published on 30 June 2016

Ascertaining the burden of invasive Salmonella disease in hospitalised febrile children aged under four years in Blantyre, Malawi

scientific article published on 17 July 2019

Assessment of the effect of candidate anti-inflammatory treatments on the interaction between meningococci and inflammatory cells in vitro in a whole blood model

scientific article published on 01 January 1996

Association of human leukocyte antigen alleles and nevirapine hypersensitivity in a Malawian HIV-infected population

scientific article published on 29 January 2013

Asymptomatic HIV-infected individuals on antiretroviral therapy exhibit impaired lung CD4(+) T-cell responses to mycobacteria

scientific article

Auditory- and somatosensory-evoked potentials in cerebral malaria and anaesthesia: a comparison.

scientific article published in October 2002

Awareness of a hospital's antibiotic policy can be improved.

scientific article published on August 2000

Bacterial genome-wide association study of hyper-virulent pneumococcal serotype 1 identifies genetic variation associated with neurotropism

scientific article published on 08 October 2020

Bacterial meningitis in Malawian adults, adolescents, and children during the era of antiretroviral scale-up and Haemophilus influenzae type b vaccination, 2000-2012.

scientific article published on 04 February 2014

Bacterial meningitis in Malawian infants <2 months of age: etiology and susceptibility to World Health Organization first-line antibiotics

scientific article published in June 2014

Barriers to successful early infant diagnosis of HIV infection at primary care level in Malawi

scientific article published on March 2015

Benefits of enhanced infection prophylaxis at antiretroviral therapy initiation by cryptococcal antigen status

scientific article published on 09 December 2020

Brain MRI and cognitive function seven years after surviving an episode of severe acute malnutrition in a cohort of Malawian children

scientific article published on 3 December 2018

Brain swelling and death in children with cerebral malaria

scientific article published on March 2015

British HIV Association Guidelines on the Use of Vaccines in HIV-Positive Adults 2015.

scientific article published on August 2016

British HIV Association guidelines for immunization of HIV-infected adults 2008

scientific article published on 01 November 2008

Bronchoalveolar CD4+ T cell responses to respiratory antigens are impaired in HIV-infected adults

scientific article

Burden of enteric fever at three urban sites in Africa and Asia: a multicentre population-based study

scientific article published on 01 December 2021

CSF Levels of Elongation Factor Tu Is Associated With Increased Mortality in Malawian Adults With <i>Streptococcus pneumoniae</i> Meningitis

scientific article published on 11 December 2020

CYP2B6 c.983T>C polymorphism is associated with nevirapine hypersensitivity in Malawian and Ugandan HIV populations

scientific article published on 20 August 2014

Capture-recapture analysis and pneumococcal meningitis estimates in England

scientific article published on 01 January 2004

Central nervous system compartmentalization of HIV-1 subtype C variants early and late in infection in young children

scientific article published on 27 December 2012

Cerebrospinal fluid transcriptional analyses reveals upregulation of IL-17, Type 1 interferon transcriptional pathways and neutrophil persistence genes associated with increased mortality from pneumococcal meningitis in adults:

scientific article published on 7 December 2018

Challenges in reducing group B Streptococcus disease in African settings

scientific article

Changing Incidence of Invasive Pneumococcal Disease in Infants Less Than 90 Days of Age Before and After Introduction of the 13-Valent Pneumococcal Conjugate Vaccine in Blantyre, Malawi: A 14-Year Hospital Based Surveillance Study

scientific article published in 2022

Changing epidemiology of bacterial meningitis among adults in England and Wales 1991-2002

article

Chronic Household Air Pollution Exposure Is Associated with Impaired Alveolar Macrophage Function in Malawian Non-Smokers

scientific article published on 25 September 2015

Chronic disease outcomes after severe acute malnutrition in Malawian children (ChroSAM): a cohort study.

scientific article published on 25 July 2016

Circulating microparticles are increased amongst people presenting with HIV and advanced immune suppression in Malawi and correlate closely with arterial stiffness: a nested case control study

scientific article published in 2022

Clinical management of urinary tract infection in women: a prospective cohort study

scientific article published on 01 February 2003

Clinical manifestations of nontuberculous mycobacteria.

scientific article published on January 2006

Community-acquired acute bacterial meningitis in adults: a clinical update

scientific article published on 01 September 2019

Comparative Genomic Analysis of Meningitis- and Bacteremia-Causing Pneumococci Identifies a Common Core Genome

scientific article published on 10 August 2015

Comparison and Correlation of Serogroup B Immunologic Assay Results and Human Antibody Responses following Three Doses of the Norwegian Meningococcal Outer Membrane Vesicle Vaccine MenBvac

scientific article published in 2007

Comparison and correlation of neisseria meningitidis serogroup B immunologic assay results and human antibody responses following three doses of the Norwegian meningococcal outer membrane vesicle vaccine MenBvac

scientific article

Corrigendum to "The UK joint specialist societies guideline on the diagnosis and management of acute meningitis and meningococcal sepsis in immunocompetent Adults" [J Infect 72 (2016) 405-438].

scientific article published on 12 April 2016

Cost-Effectiveness of Monovalent Rotavirus Vaccination of Infants in Malawi: A Postintroduction Analysis Using Individual Patient-Level Costing Data

scientific article published in May 2016

Critical determinants of the interactions of capsule-expressing Neisseria meningitidis with host cells: the role of receptor density in increased cellular targeting via the outer membrane Opa proteins.

scientific article published in October 2005

Cross-sectional health centre and community-based evaluation of the impact of pneumococcal and malaria vaccination on antibiotic prescription and usage, febrile illness and antimicrobial resistance in young children in Malawi: the IVAR study protoco

scientific article published in 2023

CryptoDex: a randomised, double-blind, placebo-controlled phase III trial of adjunctive dexamethasone in HIV-infected adults with cryptococcal meningitis: study protocol for a randomised control trial

scientific article

Cryptococcal Meningitis in Human Immunodeficiency Virus–Infected Patients in Harare, Zimbabwe ⬇️

scientific article published on February 1, 1998

Current concepts in the treatment of bacterial meningitis beyond the neonatal period.

scientific article published on August 2006

Defective pneumococcal-specific Th1 responses in HIV-infected adults precedes a loss of control of pneumococcal colonization

scientific article published on 28 September 2012

Delayed reconstitution of B cell immunity to pneumococcus in HIV-infected Malawian children on antiretroviral therapy

scientific article published on November 2014

Detection of fibronectin expression by human endothelial cells using a enzyme-linked immunosorbent assay (ELISA): enzymatic degradation by activated plasminogen

scientific article published on 01 March 1997

Detection of glycosaminoglycans on the surface of human umbilical vein endothelial cells using gold-conjugated poly-L-lysine with silver enhancement

scientific article published on 01 April 1993

Detection of herpes viruses in the cerebrospinal fluid of adults with suspected viral meningitis in Malawi.

scientific article published on 14 July 2012

Detection of tuberculosis in HIV-infected and -uninfected African adults using whole blood RNA expression signatures: a case-control study

scientific article (publication date: October 2013)

Deteriorating pneumococcal-specific B-cell memory in minimally symptomatic African children with HIV infection

scientific article published in August 2011

Determination of a Viral Load Threshold To Distinguish Symptomatic versus Asymptomatic Rotavirus Infection in a High-Disease-Burden African Population.

scientific article published on 8 April 2015

Diagnosis of childhood tuberculosis and host RNA expression in Africa

scientific article published in May 2014

Direct and possible indirect effects of vaccination on rotavirus hospitalisations among children in Malawi four years after programmatic introduction

scientific article published on 12 November 2018

Disseminated intravascular coagulation and purpura fulminans secondary to infection

article

Distinct Salmonella Enteritidis lineages associated with enterocolitis in high-income settings and invasive disease in low-income settings

scientific article published on 22 August 2016

Do multiple concurrent infections in African children cause irreversible immunological damage?

scientific article published on February 2012

Domestic River Water Use and Risk of Typhoid Fever: Results From a Case-control Study in Blantyre, Malawi

scientific article published on 01 March 2020

Drug resistance in Salmonella enterica ser. Typhimurium bloodstream infection, Malawi.

scientific article published on November 2014

Dysfunction of Endothelial Protein C Activation in Severe Meningococcal Sepsis

article

Dysregulation of coagulation in cerebral malaria.

scientific article published on 26 March 2009

Early Antiretroviral Therapy Initiation and Mortality Among Infants Diagnosed With HIV in the First 12 Weeks of Life: Experiences From Kinshasa, DR Congo and Blantyre, Malawi

scientific article published on 3 January 2017

Early T Cell Differentiation with Well-Maintained Function across the Adult Life Course in Sub-Saharan Africa

scientific article published on 29 July 2019

Early deaths during tuberculosis treatment are associated with depressed innate responses, bacterial infection, and tuberculosis progression

scientific article published in August 2011

Early management of suspected bacterial meningitis and meningococcal septicaemia in immunocompetent adults--second edition.

scientific article published in June 2005

Early signals of vaccine driven perturbation seen in pneumococcal carriage population genomic data

article

Effect of oral fluconazole 1200 mg/day on QT interval in African adults with HIV-associated cryptococcal meningitis

article

Effectiveness of a monovalent rotavirus vaccine in infants in Malawi after programmatic roll-out: an observational and case-control study

scientific article published on 29 January 2015

Electronic data capture for large scale typhoid surveillance, household contact tracing, and health utilisation survey: Strategic Typhoid Alliance across Africa and Asia

scientific article published on 09 April 2020

Emergence of double- and triple-gene reassortant G1P[8] rotaviruses possessing a DS-1-like backbone post rotavirus vaccine introduction in Malawi

scientific article published on 15 November 2017

Emerging resistance to empiric antimicrobial regimens for pediatric bloodstream infections in Malawi (1998-2017)

article

Epidemic multiple drug resistant Salmonella Typhimurium causing invasive disease in sub-Saharan Africa have a distinct genotype

scientific article published on 9 November 2009

Epidemics of invasive Salmonella enterica serovar enteritidis and S. enterica Serovar typhimurium infection associated with multidrug resistance among adults and children in Malawi

scientific article published on April 2008

Epidemiology of Severe Acute Respiratory Illness and Risk Factors for Influenza Infection and Clinical Severity among Adults in Malawi, 2011-2013

scientific article published in September 2018

Epithelial control of colonisation byStreptococcus pneumoniaeat the human mucosal surface

scientific article published on 13 March 2018

Epstein-barr virus coinfection in cerebrospinal fluid is associated with increased mortality in Malawian adults with bacterial meningitis.

scientific article published on 9 November 2011

Erratum for Kulohoma et al., Comparative genomic analysis of meningitis- and bacteremia-causing pneumococci identifies a common core genome

scientific article published in December 2015

Erratum: Distinct Salmonella Enteritidis lineages associated with enterocolitis in high-income settings and invasive disease in low-income settings

scientific article published in March 2017

Evaluating the reactivation of herpesviruses and inflammation as cardiovascular and cerebrovascular risk factors in antiretroviral therapy initiators in an African HIV-infected population (RHICCA): a protocol for a longitudinal cohort study

scientific article published on 12 September 2019

Evaluation of Xpert MTB/RIF for detection of tuberculosis from blood samples of HIV-infected adults confirms Mycobacterium tuberculosis bacteremia as an indicator of poor prognosis

scientific article published on 15 May 2013

Evaluation of pneumococcal serotyping in nasopharyngeal carriage isolates by latex agglutination, whole genome sequencing (PneumoCaT) and DNA microarray in a high pneumococcal carriage prevalence population in Malawi

scientific article published on 21 October 2020

Evidence for Naturally Acquired T Cell-Mediated Mucosal Immunity to Neisseria meningitidis ⬇️

scientific article published on October 15, 2003

Genetic characterisation of Malawian pneumococci prior to the roll-out of the PCV13 vaccine using a high-throughput whole genome sequencing approach

scientific article published on 10 September 2012

Genome-wide association study of nevirapine hypersensitivity in a sub-Saharan African HIV-infected population

scientific article

Genomic analysis of Klebsiella pneumoniae isolates from Malawi reveals acquisition of multiple ESBL determinants across diverse lineages

scientific article published on 01 May 2019

Genomic identification of a novel co-trimoxazole resistance genotype and its prevalence amongst Streptococcus pneumoniae in Malawi.

scientific article published on 29 September 2013

Genomic landscape of extended-spectrum β-lactamase resistance in Escherichia coli from an urban African setting

scientific article published on 5 March 2017

Genotypic homogeneity of multidrug resistant S. Typhimurium infecting distinct adult and childhood susceptibility groups in Blantyre, Malawi

scientific article published on 27 July 2012

Goal directed therapy for suspected acute bacterial meningitis in adults and adolescents in sub-Saharan Africa

scientific article published on 27 October 2017

Group B streptococcus vaccination in pregnant women with or without HIV in Africa: a non-randomised phase 2, open-label, multicentre trial

scientific article published on 8 February 2016

HIV coinfection influences the inflammatory response but not the outcome of cerebral malaria in Malawian children

scientific article published on 13 June 2016

HIV, antiretroviral treatment, hypertension, and stroke in Malawian adults: A case-control study.

scientific article published on 18 December 2015

HIV-associated disruption of lung cytokine networks is incompletely restored in asymptomatic HIV-infected Malawian adults on antiretroviral therapy

scientific article published in October 2017

HIV-exposed uninfected children: a growing population with a vulnerable immune system?

scientific article published on April 2014

HIV-related arterial stiffness in Malawian adults is associated with proportion of PD-1 expressing CD8 T-cells and reverses with anti-retroviral therapy

article

Haemolytic-uraemic syndrome

scientific article published on 01 April 1994

Healthcare Costs and Life-years Gained From Treatments Within the Advancing Cryptococcal Meningitis Treatment for Africa (ACTA) Trial on Cryptococcal Meningitis: A Comparison of Antifungal Induction Strategies in Sub-Saharan Africa

scientific article published on 01 August 2019

High mortality amongst adolescents and adults with bacterial meningitis in sub-Saharan Africa: an analysis of 715 cases from Malawi

scientific article published on 19 July 2013

High multiple carriage and emergence of Streptococcus pneumoniae vaccine serotype variants in Malawian children.

scientific article published on 20 June 2015

High prevalence of tuberculosis and serious bloodstream infections in ambulatory individuals presenting for antiretroviral therapy in Malawi

scientific article

High residual carriage of vaccine-serotype Streptococcus pneumoniae after introduction of pneumococcal conjugate vaccine in Malawi

scientific article published on 06 May 2020

High residual prevalence of vaccine serotype Streptococcus pneumoniae carriage 4 to 6 years after introduction of 13-valent pneumococcal conjugate vaccine in Malawi: a prospective serial cross-sectional study

scientific article published on 26 October 2018

Household air pollution and the lung microbiome of healthy adults in Malawi: a cross-sectional study

scientific article published on 11 August 2016

Household air pollution causes dose-dependent inflammation and altered phagocytosis in human macrophages

scientific article published in May 2015

How Does Blood-Retinal Barrier Breakdown Relate to Death and Disability in Pediatric Cerebral Malaria?

scientific article published on 26 August 2020

Human SARS-CoV-2 challenge uncovers local and systemic response dynamics

scientific article published on 19 June 2024

Human immunodeficiency virus (HIV) infection during pregnancy induces CD4 T-cell differentiation and modulates responses to Bacille Calmette-Guérin (BCG) vaccine in HIV-uninfected infants

scientific article

Human melioidosis, Malawi, 2011.

scientific article published in June 2013

Human papillomavirus and head and neck cancer: a systematic review and meta-analysis.

scientific article published on August 2006

Human tonsil-derived dendritic cells are poor inducers of T cell immunity to mucosally encountered pathogens

scientific article published on 26 December 2013

IFN-gamma amplifies NFkappaB-dependent Neisseria meningitidis invasion of epithelial cells via specific upregulation of CEA-related cell adhesion molecule 1.

scientific article published on 30 August 2007

Identification of a common immune signature in murine and human systemic Salmonellosis

scientific article

Identifying Streptococcus pneumoniae genes associated with invasive disease using pangenome-based whole genome sequence typing

scientific article published on 4 May 2018

Identifying genes associated with invasive disease in S. pneumoniae by applying a machine learning approach to whole genome sequence typing data

article

Immunoglobulin G subclass response to a meningococcal quadrivalent polysaccharide-diphtheria toxoid conjugate vaccine

scientific article published on April 2006

Impact and Effectiveness of 13-Valent Pneumococcal Conjugate Vaccine on Population Incidence of Vaccine and Non-Vaccine Serotype Invasive Pneumococcal Disease in Blantyre, Malawi, 2006-2018: Prospective Observational Time-Series and Case-Control Stu

scientific article published in 2020

Impact and effectiveness of 13-valent pneumococcal conjugate vaccine on population incidence of vaccine and non-vaccine serotype invasive pneumococcal disease in Blantyre, Malawi, 2006–18: prospective observational time-series and case-control studi

scientific article published in 2021

Impact of Human Immunodeficiency Virus on the Burden and Severity of Influenza Illness in Malawian Adults: A Prospective Cohort and Parallel Case-Control Study

scientific article published on 16 October 2017

Impact of Maternal HIV Infection and Placental Malaria on the Transplacental Transfer of Influenza Antibodies in Mother-Infant Pairs in Malawi, 2013-2014

scientific article published on 28 August 2019

Impact of monovalent rotavirus vaccine on diarrhoea-associated post-neonatal infant mortality in rural communities in Malawi: a population-based birth cohort study

scientific article published in September 2018

Impaired CD4 T cell memory response to Streptococcus pneumoniae precedes CD4 T cell depletion in HIV-infected Malawian adults

scientific article

Impaired maintenance of naturally acquired T-cell memory to the meningococcus in patients with B-cell immunodeficiency.

scientific article published on 6 February 2009

Impairment of pneumococcal antigen specific isotype-switched Igg memory B-cell immunity in HIV infected Malawian adults

scientific article published on 4 November 2013

Implementing early infant diagnosis of HIV infection at the primary care level: experiences and challenges in Malawi

scientific article

Improving recognition of severe illness and patient pathways in primary health services using mHealth technology in urban Blantyre, Malawi

scientific article published in December 2013

Incomplete recovery of pneumococcal CD4 T cell immunity after initiation of antiretroviral therapy in HIV-infected malawian adults

scientific article

Infectious diseases

scientific article published on 01 April 1991

Inflammatory Phenotypes Predict Changes in Arterial Stiffness following ART Initiation

scientific article published on 27 February 2020

Influence of age and carriage status on salivary IgA to Neisseria meningitidis

scientific article published on 25 April 2005

Influenza-like illness is associated with high pneumococcal carriage density in Malawian children

scientific article published on 22 July 2020

Infrequent Transmission of Monovalent Human Rotavirus Vaccine Virus to Household Contacts of Vaccinated Infants in Malawi

article

Innate and adaptive nasal mucosal immune responses following experimental human pneumococcal colonization

scientific article published on 30 July 2019

Interactions of Meningococci with Endothelium

scientific article published on January 1, 2001

Intestinal Perforations Associated With a High Mortality and Frequent Complications During an Epidemic of Multidrug-resistant Typhoid Fever in Blantyre, Malawi

scientific article published on 01 July 2020

Intracontinental spread of human invasive Salmonella Typhimurium pathovariants in sub-Saharan Africa

scientific article

Invasive Salmonella Discussed in Africa Consensus Meeting 2014, Blantyre, Malawi. ⬇️

scientific article

Invasive Salmonella infections in Africa

scientific article published in November 2014

Invasive non-typhoid salmonellae establish systemic intracellular infection in HIV-infected adults: an emerging disease pathogenesis

scientific article published on April 2010

Invasive non-typhoidal salmonella disease: an emerging and neglected tropical disease in Africa.

scientific article

Invasiveness potential of pneumococcal serotypes in children after introduction of PCV13 in Blantyre, Malawi

scientific article published in 2023

Investigation of platelet–neutrophil interactions in whole blood by flow cytometry ⬇️

scientific article published on December 1, 1997

Ischemic stroke as a complication of cryptococcal meningitis and immune reconstitution inflammatory syndrome: a case report

scientific article published on 16 October 2018

Kinetics of Mycobacterium tuberculosis-specific IFN-γ responses and sputum bacillary clearance in HIV-infected adults during treatment of pulmonary tuberculosis

scientific article published on 28 May 2015

Laboratory evidence of disseminated intravascular coagulation is associated with a fatal outcome in children with cerebral malaria despite an absence of clinically evident thrombosis or bleeding

scientific article

Lack of decline in childhood malaria, Malawi, 2001-2010.

scientific article published in February 2012

Leave no one behind: response to new evidence and guidelines for the management of cryptococcal meningitis in low-income and middle-income countries

scholarly article by Angela Loyse et al published 18 October 2018 in Lancet Infectious Diseases

Long-term effects of severe acute malnutrition on lung function in Malawian children: a cohort study

scientific article published on 5 April 2017

Longitudinal lactate levels from routine point-of-care monitoring in adult Malawian antiretroviral therapy patients: associations with stavudine toxicities

scientific article published on 7 August 2013

Loss of Humoral and Cellular Immunity to Invasive Nontyphoidal Salmonella during Current or Convalescent Plasmodium falciparum Infection in Malawian Children ⬇️

scientific article published on 17 May 2017

Loss of Multicellular Behavior in Epidemic African Nontyphoidal Salmonella enterica Serovar Typhimurium ST313 Strain D23580.

scientific article published on March 2016

Loss of endothelial protein C receptors links coagulation and inflammation to parasite sequestration in cerebral malaria in African children

scientific article published on 05 June 2013

Lumbar puncture in the management of adults with suspected bacterial meningitis--a survey of practice.

scientific article published on 4 October 2005

Management of diagnostic uncertainty in children with possible meningitis: a qualitative study ⬇️

scientific article published on August 1, 2003

Management of meningococcal infections.

scientific article

Management of severe non-TB bacterial infection in HIV-infected adults

scientific article published on February 2015

Managing acute cystitis in women

scientific article published on 01 April 2004

Mathematical Modeling to Assess the Drivers of the Recent Emergence of Typhoid Fever in Blantyre, Malawi

scientific article published in November 2015

Methodological challenges in measuring vaccine effectiveness using population cohorts in low resource settings

scientific article (publication date: 11 September 2015)

Methods and challenges in measuring the impact of national pneumococcal and rotavirus vaccine introduction on morbidity and mortality in Malawi

scientific article published on 24 April 2015

Microinvasion by Streptococcus pneumoniae induces epithelial innate immunity during colonisation at the human mucosal surface

scientific article published on 16 July 2019

Modelling the Contributions of Malaria, HIV, Malnutrition and Rainfall to the Decline in Paediatric Invasive Non-typhoidal Salmonella Disease in Malawi

scientific article published on 31 July 2015

Modulation of the endothelial procoagulant response to lipopolysaccharide and tumour necrosis factor-alpha in-vitro: the effects of dexamethasone, pentoxifylline, iloprost and a polyclonal anti-human IL-1 alpha antibody

scientific article published on 01 July 1995

Molecular Surveillance Identifies Multiple Transmissions of Typhoid in West Africa

scientific article published on 22 September 2016

Monocyte unresponsiveness and impaired IL1β, TNFα and IL7 production are associated with a poor outcome in Malawian adults with pulmonary tuberculosis

scientific article published on 13 November 2015

Mucosal immunity and optimizing protection with meningococcal serogroup B vaccines

scientific article published on 15 February 2006

Mucosal immunity in healthy adults after parenteral vaccination with outer-membrane vesicles from Neisseria meningitidis serogroup B

scientific article published on 01 September 2008

Mucosal immunity in resource-limited setting: is the battle ground different?

scientific article

Multiplex Real-Time PCR Detection of Intestinal Protozoa in HIV-Infected Children in Malawi, Enterocytozoon Bieneusi is Common and Associated with Gastrointestinal Complaints and May Delay BMI (Nutritional Status) Recovery.

scientific article published on 14 May 2018

Naturally-acquired influenza-specific CD4+ T-cell proliferative responses are impaired in HIV-infected African adults

scientific article

Neisseria lactamica selectively induces mitogenic proliferation of the naive B cell pool via cell surface Ig.

scientific article published on 13 August 2010

Neutrophil response to Neisseria meningitidis: inhibition of adhesion molecule expression and phagocytosis by recombinant bactericidal/permeability-increasing protein (rBPI21)

scientific article published on 01 May 1999

Non-secretor histo-blood group antigen phenotype is associated with reduced risk of clinical rotavirus vaccine failure in Malawian infants

scientific article published on 01 September 2019

Omicron B.1.1.529 variant infections associated with severe disease are uncommon in a COVID-19 under-vaccinated, high SARS-CoV-2 seroprevalence population in Malawi

scientific article published in 2023

One-year Mortality Outcomes From the Advancing Cryptococcal Meningitis Treatment for Africa Trial of Cryptococcal Meningitis Treatment in Malawi

scientific article published on 01 January 2020

Osmotic therapies added to antibiotics for acute bacterial meningitis

scientific article published in 2013

Osmotic therapies added to antibiotics for acute bacterial meningitis.

scientific article published on 6 February 2018

Osmotic therapies as adjuncts to antibiotics for acute bacterial meningitis

scientific article

Pan-GWAS of Streptococcus agalactiae Highlights Lineage-Specific Genes Associated with Virulence and Niche Adaptation

scientific article published on 09 June 2020

Parenteral influenza vaccination influences mucosal and systemic T cell-mediated immunity in healthy adults

scientific article published on 27 October 2004

Performance of HIV Rapid Tests Among Breastfeeding, Malawian Infants

scientific article published on 27 October 2016

Persistent endothelial activation and inflammation after Plasmodium falciparum Infection in Malawian children

scientific article published on 17 September 2013

Pharmacodynamic Modeling of Bacillary Elimination Rates and Detection of Bacterial Lipid Bodies in Sputum to Predict and Understand Outcomes in Treatment of Pulmonary Tuberculosis

scientific article published on 16 March 2015

Phenotypic Correlates of HIV-1 Macrophage Tropism

scientific article published on 2 September 2015

Phylogeographical analysis of the dominant multidrug-resistant H58 clade of Salmonella Typhi identifies inter- and intracontinental transmission events

scientific article published on 11 May 2015

Piliation of invasive Streptococcus pneumoniae isolates in the era before pneumococcal conjugate vaccine introduction in Malawi ⬇️

scientific article published on 11 September 2013

Platelet and soluble CD40L in meningococcal sepsis.

scientific article

Platelet satellitism

scientific article published on 01 July 1998

Pleural tuberculosis in Harare, Zimbabwe: the relationship between human immunodeficiency virus, CD4 lymphocyte count, granuloma formation and disseminated disease.

scientific article published in January 1998

Pneumococcal pneumonia and carriage in Africa before and after introduction of pneumococcal conjugate vaccines, 2000-2019: protocol for systematic review

scientific article published on 13 November 2019

Polysaccharide-specific memory B cells generated by conjugate vaccines in humans conform to the CD27+IgG+ isotype-switched memory B Cell phenotype and require contact-dependent signals from bystander T cells activated by bacterial proteins to differ

scientific article published on 13 November 2013

Polysaccharide–protein conjugate vaccination induces antibody production but not sustained B-cell memory in the human nasopharyngeal mucosa ⬇️

scientific article published on July 18, 2012

Population Impact and Effectiveness of Monovalent Rotavirus Vaccination in Urban Malawian Children 3 Years After Vaccine Introduction: Ecological and Case-Control Analyses

scientific article published on May 2016

Population genetic structure, antibiotic resistance, capsule switching and evolution of invasive pneumococci before conjugate vaccination in Malawi ⬇️

scientific article published on 12 July 2017

Population pharmacokinetic and pharmacogenetic analysis of nevirapine in hypersensitive and tolerant HIV-infected patients from Malawi

scientific article published on 11 November 2013

Population pharmacokinetic and pharmacogenetic analysis of nevirapine in hypersensitive and tolerant HIV-infected patients from Malawi

article

Postinfectious purpura fulminans caused by an autoantibody directed against protein S ⬇️

scientific article published on September 1, 1995

Potential role for mucosally active vaccines against pneumococcal pneumonia

scientific article

Preclinical Development of Virulence Attenuated <i>Streptococcus pneumoniae</i> Strains Able to Enhance Protective Immunity Against Pneumococcal Infection

scientific article published on 17 December 2020

Prediction of Outcome From Adult Bacterial Meningitis in a High-HIV-Seroprevalence, Resource-Poor Setting Using the Malawi Adult Meningitis Score (MAMS).

scientific article published on 7 December 2016

Predictive value of C-reactive protein for tuberculosis, bloodstream infection or death among HIV-infected individuals with chronic, non-specific symptoms and negative sputum smear microscopy.

scientific article

Predictors of Uptake and Timeliness of Newly Introduced Pneumococcal and Rotavirus Vaccines, and of Measles Vaccine in Rural Malawi: A Population Cohort Study

scientific article published on 6 May 2016

Prevalence and spectrum of illness among hospitalized adults with malaria in Blantyre, Malawi

scientific article

Prostacyclin concentrations in haemolytic uraemic syndrome after acute shigellosis.

scientific article published on July 1992

Public engagement in Malawi through a health-talk radio programme 'Umoyo nkukambirana': A mixed-methods evaluation

scientific article published on 30 June 2016

Pulmonary tuberculosis in Harare, Zimbabwe: analysis by spoligotyping.

scientific article published on May 1998

Quality of in-hospital care for adults with acute bacterial meningitis: a national retrospective survey.

scientific article published on November 2006

Raltegravir-intensified initial antiretroviral therapy in advanced HIV disease in Africa: A randomised controlled trial

article

Rapid emergence of multidrug resistant, H58-lineage Salmonella typhi in Blantyre, Malawi.

scientific article published on 24 April 2015

Rapid emergence of resistance to penicillin and trimethoprim-sulphamethoxazole in invasive Streptococcus pneumoniae in Zimbabwe.

scientific article

Re: Moxifloxacin should not be discounted in the treatment of bacterial meningitis

scientific article published on 3 June 2016

Recognising and treatment seeking for acute bacterial meningitis in adults and children in resource-poor settings: a qualitative study

scientific article published on 4 July 2013

Recombination in Streptococcus pneumoniae Lineages Increase with Carriage Duration and Size of the Polysaccharide Capsule

scientific article published on 27 September 2016

Reduction of the anticoagulant activity of glycosaminoglycans on the surface of the vascular endothelium by endotoxin and neutrophils: evaluation by an amidolytic assay

scientific article published on September 15, 1992

Region-specific diversification of the highly virulent serotype 1 Streptococcus pneumoniae

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Unstructured treatment interruption: an important risk factor for arterial stiffness in adult Malawian patients with antiretroviral treatment

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Whole blood model of meningococcal bacteraemia--a method for exploring host-bacterial interactions

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