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List of works by Cecilia Garlanda

A 'Multiomic' Approach of Saliva Metabolomics, Microbiota, and Serum Biomarkers to Assess the Need of Hospitalization in Coronavirus Disease 2019

scientific article published on 07 February 2022

AHR drives the development of gut ILC22 cells and postnatal lymphoid tissues via pathways dependent on and independent of Notch

scientific article

Absence of Toll-IL-1 receptor 8/single immunoglobulin IL-1 receptor-related molecule reduces house dust mite-induced allergic airway inflammation in mice

scientific article

Amyotrophic lateral sclerosis transcriptomics reveals immunological effects of low-dose interleukin-2

scientific article published on 29 June 2021

An acidic microenvironment sets the humoral pattern recognition molecule PTX3 in a tissue repair mode

scientific article published on 11 May 2015

An alternative role of C1q in cell migration and tissue remodeling: contribution to trophoblast invasion and placental development

scientific article

An integrated view of humoral innate immunity: pentraxins as a paradigm

scientific article

Anti-tumor activity of cytokines against opportunistic vascular tumors in mice

scientific article published on 01 March 1996

Author Correction: Complement as a target in COVID-19?

scientific article published on 12 June 2020

Cancer-related inflammation, the seventh hallmark of cancer: links to genetic instability

scientific article

Cardioprotective Function of the Long Pentraxin PTX3 in Acute Myocardial Infarction

Cerebrospinal fluid pentraxin 3 early after subarachnoid hemorrhage is associated with vasospasm

scientific article

Chorionic gonadotropin up-regulates long pentraxin 3 expression in myeloid cells

scientific article published on 6 August 2008

Cigarette smoke induces PTX3 expression in pulmonary veins of mice in an IL-1 dependent manner

scientific article published on 4 October 2010

Circulating biomarkers and cardiac function over 3 years after chemotherapy with anthracyclines: the ICOS-ONE trial

scientific article published on 01 May 2020

Complement C3 vs C5 inhibition in severe COVID-19: Early clinical findings reveal differential biological efficacy

scientific article published on 19 September 2020

Complement Dependent Amplification of the Innate Response to a Cognate Microbial Ligand by the Long Pentraxin PTX3

scientific article published on 01 November 2007

Complement activation promoted by the lectin pathway mediates C3aR-dependent sarcoma progression and immunosuppression

scientific article published on 18 February 2021

Complement as a target in COVID-19?

scientific article published on 23 April 2020

Complementary Roles of Short and Long Pentraxins in the Complement-Mediated Immune Response to Aspergillus fumigatus Infections

scientific article published in 2021

Complexity and complementarity of outer membrane protein A recognition by cellular and humoral innate immunity receptors

scientific article published in May 2005

Coregulation in human leukocytes of the long pentraxin PTX3 and TSG-6.

scientific article

Correction: The soluble pattern recognition receptor PTX3 links humoral innate and adaptive immune responses by helping marginal zone B cells

scientific article published on 18 April 2017

Cytokine decoy and scavenger receptors as key regulators of immunity and inflammation

scientific article

Cytokine regulation of endothelial cell function: New molecules in an old paradigm ⬇️

scholarly article

Damping excessive inflammation and tissue damage in Mycobacterium tuberculosis infection by Toll IL-1 receptor 8/single Ig IL-1-related receptor, a negative regulator of IL-1/TLR signaling

scientific article published on 01 September 2007

Decoys and Regulatory "Receptors" of the IL-1/Toll-Like Receptor Superfamily

scientific article published on 09 July 2013

Defective dendritic cell migration and activation of adaptive immunity in PI3Kgamma-deficient mice

scientific article

Deficiency of the Long Pentraxin PTX3 Promotes Vascular Inflammation and Atherosclerosis

Detrimental and protective action of microglial extracellular vesicles on myelin lesions: astrocyte involvement in remyelination failure

scientific article published on 30 July 2019

Early and transient release of leukocyte pentraxin 3 during acute myocardial infarction

scientific article

Editorial: The Role of Pentraxins: From Inflammation, Tissue Repair and Immunity to Biomarkers

scientific article published on 03 December 2019

Elevated maternal levels of the long pentraxin 3 (PTX3) in preeclampsia and intrauterine growth restriction

Endogenous and exogenous pentraxin-3 limits postischemic acute and chronic kidney injury

Epigenetic regulation of the extrinsic oncosuppressor PTX3 gene in inflammation and cancer

scientific article

Erratum: IL-1 family nomenclature

scholarly article by Charles A. Dinarello et al published March 2011 in Nature Immunology

Evolution of the pentraxin family: the new entry PTX4

scientific article

Expression and function of IL-1R8 (TIR8/SIGIRR): a regulatory member of the IL-1 receptor family in platelets

scientific article published on 13 June 2016

Extracellular and intracellular decoys in the tuning of inflammatory cytokines and Toll-like receptors: the new entry TIR8/SIGIRR.

scientific article published on 12 December 2003

Extracellular and nuclear roles of IL-37 after spinal cord injury

scientific article published on 28 September 2020

Extracellular forms of IL-37 inhibit innate inflammation in vitro and in vivo but require the IL-1 family decoy receptor IL-1R8.

scientific article

First trimester PTX3 levels in women who subsequently develop preeclampsia and fetal growth restriction

scientific article published on 01 January 2009

Fluid phase recognition molecules in neutrophil-dependent immune responses

scientific article

Follicular Fuid Levels of the Long Pentraxin PTX3

Gene and protein expression in response to different growth temperatures and oxygen availability in Burkholderia thailandensis.

scientific article

Glucose availability enhances lipopolysaccharide production and immunogenicity in the opportunistic pathogen Acinetobacter baumannii.

scientific article published on 02 March 2016

High IL-1R8 expression in breast tumors promotes tumor growth and contributes to impaired antitumor immunity.

scientific article published on 9 May 2017

Humoral innate immunity at the crossroad between microbe and matrix recognition: The role of PTX3 in tissue damage

scientific article

IL-1 and IL-1 regulatory pathways in cancer progression and therapy

scientific article published in January 2018

IL-1 family nomenclature

scientific article

IL-1F5 mediates anti-inflammatory activity in the brain through induction of IL-4 following interaction with SIGIRR/TIR8

scientific article published on 18 February 2008

IL-1R8 is a checkpoint in NK cells regulating anti-tumour and anti-viral activity.

scientific article

IL-37 exerts therapeutic effects in experimental autoimmune encephalomyelitis through the receptor complex IL-1R5/IL-1R8

scientific article published on 01 January 2021

IL-37 inhibits inflammasome activation and disease severity in murine aspergillosis

scientific article (publication date: November 2014)

IL-37 requires the receptors IL-18Rα and IL-1R8 (SIGIRR) to carry out its multifaceted anti-inflammatory program upon innate signal transduction

scientific article

IL1R8 Deficiency Drives Autoimmunity-Associated Lymphoma Development

scientific article published on 24 April 2019

Increased Susceptibility to Colitis-Associated Cancer of Mice Lacking TIR8, an Inhibitory Member of the Interleukin-1 Receptor Family

scientific article published on 01 July 2007

Inflammation and neutrophil extracellular traps in cerebral cavernous malformation

scientific article published on 25 March 2022

Inflammation-mediated promotion of invasion and metastasis

scientific article published on June 2010

Influence of pentraxin 3 (PTX3) genetic variants on myocardial infarction risk and PTX3 plasma levels

scientific article

Innate immunity, hemostasis and matrix remodeling: PTX3 as a link

scientific article published on 20 November 2016

Interactions of the humoral pattern recognition molecule PTX3 with the complement system ⬇️

scientific article published on November 1, 2012

Interleukin 1 Receptor 8 Deficiency Does not Impact Atherosclerosis

scientific article published in 2022

Interleukin 37 reverses the metabolic cost of inflammation, increases oxidative respiration, and improves exercise tolerance

scientific article published on 13 February 2017

Interleukin-1 and Related Cytokines in the Regulation of Inflammation and Immunity

scientific article published on 01 April 2019

Interleukin-1alpha and HMGB1 mediate hippocampal dysfunction in SIGIRR-deficient mice

scientific article published in March 2011

Interplay between Myeloid Cells and Humoral Innate Immunity

scientific article published on December 2016

Intestinal inflammation in mice deficient in Tir8, an inhibitory member of the IL-1 receptor family

scholarly article

Intraperitoneal adoptive transfer of mesenchymal stem cells enhances recovery from acid aspiration acute lung injury in mice

scientific article published on 06 March 2017

Lack of IL-1R8 in neurons causes hyperactivation of IL-1 receptor pathway and induces MECP2-dependent synaptic defects

scientific article published on 28 March 2017

Lack of SIGIRR/TIR8 aggravates hydrocarbon oil-induced lupus nephritis

scientific article published in April 2010

Lack of TIR8/SIGIRR triggers progression of chronic lymphocytic leukemia in mouse models

scientific article published on 7 June 2011

Lack of Toll IL-1R8 Exacerbates Th17 Cell Responses in Fungal Infection

article

Lack of the long pentraxin PTX3 promotes autoimmune lung disease but not glomerulonephritis in murine systemic lupus erythematosus

scientific article

Ligands and Receptors of the Interleukin-1 Family in Immunity and Disease ⬇️

scientific article published on November 20, 2013

Long pentraxin 3, a key component of innate immunity, is modulated by high-density lipoproteins in endothelial cells

scientific article published on 24 January 2008

Long pentraxin 3/tumor necrosis factor-stimulated gene-6 interaction: a biological rheostat for fibroblast growth factor 2-mediated angiogenesis

scientific journal article

Long pentraxin PTX3 is associated with mortality and disease severity in severe Leptospirosis

scientific article

Long pentraxin PTX3 is upregulated systemically and centrally after experimental neurotrauma, but its depletion leaves unaltered sensorimotor deficits or histopathology

scientific article published on 05 May 2021

Long pentraxin-3 as an epithelial-stromal fibroblast growth factor-targeting inhibitor in prostate cancer.

scientific article published on June 2013

Macrophage diversity and polarization in atherosclerosis: a question of balance

scientific article published on 20 August 2009

Macrophage expression and prognostic significance of the long pentraxin PTX3 in COVID-19

scientific article published on 18 November 2020

Mesenchymal Stromal Cell-Derived PTX3 Promotes Wound Healing via Fibrin Remodeling

scientific article published in January 2016

MiR-146b Mediates Endotoxin Tolerance in Human Phagocytes

scientific article published on 14 September 2015

Molecular pathways and targets in cancer-related inflammation

scientific article published on April 2010

Negative regulatory receptors of the IL-1 family

scientific article

Neutrophils Driving Unconventional T Cells Mediate Resistance against Murine Sarcomas and Selected Human Tumors

scientific article published on 27 June 2019

Neutrophils in innate and adaptive immunity

scientific article published on 04 April 2013

Non-redundant role of the long pentraxin PTX3 in anti-fungal innate immune response

scientific article

Nonredundant role of CCRL2 in lung dendritic cell trafficking

scientific article

Occurrence and significance of tumor-associated neutrophils in patients with colorectal cancer

scientific article

Optical in vivo imaging detection of preclinical models of gut tumors through the expression of integrin αVβ3

scientific article published on 31 July 2018

PTX3 acts as an extrinsic oncosuppressor

scientific article published on 11 July 2015

PTX3 as a paradigm for the interaction of pentraxins with the complement system

scientific article published on February 2013

PTX3 expression in the heart tissues of patients with myocardial infarction and infectious myocarditis

article by Manuela Nebuloni et al published January 2011 in Cardiovascular Pathology

PTX3 is an extrinsic oncosuppressor regulating complement-dependent inflammation in cancer

scientific article

PTX3 orchestrates tissue repair

scientific article published on 2 September 2015

PTX3 plays a key role in the organization of the cumulus oophorus extracellular matrix and in in vivo fertilization

scientific article

PTX3 predicts severe disease in febrile patients at the emergency department

scientific article published on 2 December 2009

PTX3, a Humoral Pattern Recognition Molecule, in Innate Immunity, Tissue Repair, and Cancer

scientific article published in April 2018

PTX3, a humoral pattern recognition molecule at the interface between microbe and matrix recognition

scientific article

Pathogen Recognition by the Long Pentraxin PTX3 ⬇️

scientific article published on June 2, 2011

Pathogenic NLRP3 Inflammasome Activity during Candida Infection Is Negatively Regulated by IL-22 via Activation of NLRC4 and IL-1Ra

scientific article

Pathways connecting inflammation and cancer

scientific article published on February 2008

Pattern recognition by pentraxins

scientific article

Pentraxin 3 deficiency protects from the metabolic inflammation associated to diet-induced obesity

scientific article published on 01 November 2019

Pentraxin 3 mediates neurogenesis and angiogenesis after cerebral ischaemia.

scientific article

Pentraxin 3 plasma levels at graft-versus-host disease onset predict disease severity and response to therapy in children given haematopoietic stem cell transplantation

scientific article

Pentraxin 3 promotes long-term cerebral blood flow recovery, angiogenesis, and neuronal survival after stroke

article

Pentraxin 3 protects from MCMV infection and reactivation through TLR sensing pathways leading to IRF3 activation

scientific article published on 13 July 2006

Pentraxin 3 recruits complement factor H to protect against oxidative stress-induced complement and inflammasome overactivation

scientific article

Pentraxin 3 regulates synaptic function by inducing AMPA receptor clustering via ECM remodeling and β1-integrin

scientific article published on 05 November 2018

Pentraxin 3, a non-redundant soluble pattern recognition receptor involved in innate immunity

scientific article

Pentraxin-3 is upregulated in the central nervous system during MS and EAE, but does not modulate experimental neurological disease

scientific article published on 18 November 2015

Pentraxins and Atherosclerosis

Pentraxins and atherosclerosis: the role of PTX3.

scientific article published on January 2011

Pentraxins as a key component of innate immunity

scientific article

Pentraxins at the crossroads between innate immunity, inflammation, matrix deposition, and female fertility

scientific article

Pentraxins in Innate Immunity and Inflammation

Pentraxins in Vascular Pathology: The Role of PTX3

scholarly article

Pentraxins in humoral innate immunity

scientific article published on January 2012

Pentraxins in innate immunity and inflammation

scientific article published on January 2006

Pentraxins in innate immunity: from C-reactive protein to the long pentraxin PTX3.

scientific article

Pentraxins in innate immunity: lessons from PTX3.

scientific article published on 04 August 2010

Pentraxins in the activation and regulation of innate immunity

scientific article

Pentraxins, humoral innate immunity and tissue injury

scientific article published on 23 June 2008

Pentraxins: multifunctional proteins at the interface of innate immunity and inflammation

scientific article published on March 2009

Plasma pentraxin-3 as a marker of bioincompatibility in hemodialysis patients

scientific article published on 01 January 2012

Platelet-macrophage partnership in innate immunity and inflammation

scientific article published in August 2013

Production of the Long Pentraxin PTX3 by Myeloid Dendritic Cells: Linking Cellular and Humoral Innate Immunity

Production of the long pentraxin PTX3 in advanced atherosclerotic plaques

scientific article

Production of the soluble pattern recognition receptor PTX3 by myeloid, but not plasmacytoid, dendritic cells

scientific article published in October 2003

Prognostic and diagnostic potential of local and circulating levels of pentraxin 3 in lung cancer patients

scientific article published on 27 August 2015

Prototypic long pentraxin PTX3 is present in breast milk, spreads in tissues, and protects neonate mice from Pseudomonas aeruginosa lung infection

scientific article published on 17 July 2013

Recognition and inhibition of SARS-CoV-2 by humoral innate immunity pattern recognition molecules

scientific article

Recognition of Neisseria meningitidis by the long pentraxin PTX3 and its role as an endogenous adjuvant

scientific article

Regulation of PTX3, a key component of humoral innate immunity in human dendritic cells: stimulation by IL-10 and inhibition by IFN-

scientific article published on 03 February 2006

Regulation of leukocyte recruitment by the long pentraxin PTX3.

scientific article published on 7 March 2010

Regulatory Role of IL-1R8 in Immunity and Disease

scientific article published in 2016

Regulatory pathways in inflammation

scientific article published on 26 March 2007

Repeated 5-day cycles of low dose aldesleukin in amyotrophic lateral sclerosis (IMODALS): A phase 2a randomised, double-blind, placebo-controlled trial

scientific article published on 01 July 2020

Resident dendritic cells prevent postischemic acute renal failure by help of single Ig IL-1 receptor-related protein.

scientific article published on 19 August 2009

Response of CFTR-deficient mice to long-term chronic Pseudomonas aeruginosa infection and PTX3 therapy

scientific article

Role Of Long Pentraxin 3 (PTX3) In Wound Closure Induced By Bone Marrow-Derived Mesenchymal Stromal Cells ⬇️

scholarly article

Role of Toll interleukin-1 receptor (IL-1R) 8, a negative regulator of IL-1R/Toll-like receptor signaling, in resistance to acute Pseudomonas aeruginosa lung infection

scientific article published on 24 October 2011

Role of a fluid-phase PRR in fighting an intracellular pathogen: PTX3 in Shigella infection

scientific article published on 07 December 2018

Role of complement and Fc receptors in the protective activity of the long pentraxin PTX3 against Aspergillus fumigatus

scientific article published on 09 September 2010

Role of pentraxin 3 in shaping arthritogenic alphaviral disease: from enhanced viral replication to immunomodulation. ⬇️

scientific article

SIGIRR/TIR-8 is an inhibitor of toll-like receptor signaling in primary human cells and regulates inflammation in models of rheumatoid arthritis

article

Serum amyloid P component is an essential element of resistance against Aspergillus fumigatus

scientific article published on 18 June 2021

Sexual Dimorphism in Innate Immunity.

scientific article published on 30 September 2017

Single immunoglobulin interleukin-1 receptor-related molecule impairs host defense during pneumonia and sepsis caused by Streptococcus pneumoniae.

scientific article

Structure and function of the long pentraxin PTX3 glycosidic moiety: fine-tuning of the interaction with C1q and complement activation.

scientific article published in September 2006

TIR8/SIGIRR is an Interleukin-1 Receptor/Toll Like Receptor Family Member with Regulatory Functions in Inflammation and Immunity

scientific article published on 29 October 2012

TIR8/SIGIRR: an IL-1R/TLR family member with regulatory functions in inflammation and T cell polarization

scientific article published on 21 August 2009

The "sweet" side of a long pentraxin: how glycosylation affects PTX3 functions in innate immunity and inflammation

scientific article published on January 2012

The Dual Complexity of PTX3 in Health and Disease: A Balancing Act?

scientific article

The Long Pentraxin 3 Contributes to Joint Inflammation in Gout by Facilitating the Phagocytosis of Monosodium Urate Crystals

scientific article published on 04 February 2019

The Long Pentraxin PTX3 Is an Endogenous Inhibitor of Hyperoxaluria-Related Nephrocalcinosis and Chronic Kidney Disease

The Long Pentraxin PTX3 as a Humoral Innate Immunity Functional Player and Biomarker of Infections and Sepsis

The Long Pentraxin PTX3 as a Link Between Innate Immunity, Tissue Remodeling, and Cancer

The Therapeutic Potential of the Humoral Pattern Recognition Molecule PTX3 in Chronic Lung Infection Caused by Pseudomonas aeruginosa

scientific article published on 25 March 2011

The Toll-IL-1R Member Tir8/SIGIRR Negatively Regulates Adaptive Immunity against Kidney Grafts

scientific article published on 04 September 2009

The Yin Yang of Cancer Related Inflammation

article

The Yin-Yang of tumor-associated macrophages in neoplastic progression and immune surveillance

scientific article published on April 2008

The acute-phase protein PTX3 is an essential mediator of glial scar formation and resolution of brain edema after ischemic injury

scientific article published on 18 December 2013

The clearance of cell remnants and the regeneration of the injured muscle depend on soluble pattern recognition receptor PTX3.

scientific article

The complement system in Aspergillus fumigatus infections and its crosstalk with pentraxins

scientific article published on 28 January 2020

The expression pattern of TIR8 is conserved among vertebrates

scientific article published on 24 March 2009

The first case of COVID-19 treated with the complement C3 inhibitor AMY-101

scientific article published on 29 April 2020

The humoral pattern recognition molecule PTX3 is a key component of innate immunity against urinary tract infection

scientific article published on April 2014

The humoral pattern recognition receptor PTX3 is stored in neutrophil granules and localizes in extracellular traps

scientific article

The immunoproteasome controls the availability of the cardioprotective pattern recognition molecule Pentraxin3.

scientific article

The interleukin-1 family: back to the future

scientific article

The long pentraxin 3 is a soluble and cell-associated component of the human semen

scientific article published on 30 December 2007

The long pentraxin PTX3 as a correlate of cancer-related inflammation and prognosis of malignancy in gliomas

scientific article published on 9 May 2013

The long pentraxin PTX3 as a key component of humoral innate immunity and a candidate diagnostic for inflammatory diseases

scientific article published on 20 December 2014

The long pentraxin PTX3 as a link among innate immunity, inflammation, and female fertility

scientific article

The long pentraxin PTX3 as a prototypic humoral pattern recognition receptor: interplay with cellular innate immunity

scientific article published on January 2009

The long pentraxin PTX3 in human endometrium: regulation by steroids and trophoblast products

scientific article published on 29 November 2007

The long pentraxin PTX3 in vascular pathology

scientific article published on 23 August 2006

The long pentraxin PTX3: A prototypical sensor of tissue injury and a regulator of homeostasis

scientific article published in November 2017

The long pentraxin PTX3: a modulator of the immunoinflammatory response in atherosclerosis and cardiovascular diseases.

scientific article published on February 2010

The long pentraxin PTX3: a paradigm for humoral pattern recognition molecules

scientific article published on 25 March 2013

The pentraxins PTX3 and SAP in innate immunity, regulation of inflammation and tissue remodelling

scientific article

The soluble pattern recognition receptor PTX3 links humoral innate and adaptive immune responses by helping marginal zone B cells

scientific article published on 12 September 2016

The soluble pattern recognition receptor pentraxin-3 in innate immunity, inflammation and fertility.

scientific article

The tumor microenvironment of colorectal cancer: stromal TLR-4 expression as a potential prognostic marker

scientific article

The yin-yang of the interaction between myelomonocytic cells and NK cells

scientific article published on 19 August 2018

Tir8/Sigirr prevents murine lupus by suppressing the immunostimulatory effects of lupus autoantigens.

scientific article published on 21 July 2008

Tir8/Sigirr prevents murine lupus by suppressing the immunostimulatory effects of lupus autoantigens.

scientific article

Toll IL-1R8/single Ig IL-1-related receptor regulates psoriasiform inflammation through direct inhibition of innate IL-17A expression by γδ T cells

scientific article published on 14 August 2013

Toll-like receptor signaling and SIGIRR in renal fibrosis upon unilateral ureteral obstruction

scientific article published on 22 April 2011

Treating experimental arthritis with the innate immune inhibitor interleukin-37 reduces joint and systemic inflammation

scientific article published on 26 August 2016

Treating experimental arthritis with the innate immune inhibitor interleukin-37 reduces joint and systemic inflammation

scientific article published on 01 December 2017

Tumor associated macrophages and neutrophils in cancer

scientific article published on 17 June 2013

Tumor associated macrophages and neutrophils in tumor progression

scientific article

Tumor-associated macrophages and the related myeloid-derived suppressor cells as a paradigm of the diversity of macrophage activation

scientific article published on 21 February 2009

Tuning inflammation and immunity by the negative regulators IL-1R2 and IL-1R8.

scientific article published in January 2018

Unique pattern of expression and inhibition of IL-1 signaling by the IL-1 receptor family member TIR8/SIGIRR.

scientific article

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