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List of works by Eugenio Morelli

A 13 mer LNA-i-miR-221 Inhibitor Restores Drug Sensitivity in Melphalan-Refractory Multiple Myeloma Cells.

scientific article published on 2 November 2015

Bortezomib induces anti-multiple myeloma immune response mediated by cGAS/STING pathway activation

scientific article published on 23 April 2021

Drugging the lncRNA MALAT1 via LNA gapmeR ASO inhibits gene expression of proteasome subunits and triggers anti-multiple myeloma activity.

scientific article published on 22 February 2018

In vitro and in vivo activity of a novel locked nucleic acid (LNA)-inhibitor-miR-221 against multiple myeloma cells.

scientific article published on 21 February 2014

Inhibition of Haspin Kinase Promotes Cell-Intrinsic and Extrinsic Antitumor Activity

scientific article published on 27 December 2019

Inhibition of histone methyltransferase DOT1L silences ERα gene and blocks proliferation of antiestrogen-resistant breast cancer cells

article

Inhibition of miR-21 restores RANKL/OPG ratio in multiple myeloma-derived bone marrow stromal cells and impairs the resorbing activity of mature osteoclasts

scientific article published on 24 June 2015

JunB is a key regulator of multiple myeloma bone marrow angiogenesis

scientific article published on 18 May 2021

MiR-29b antagonizes the pro-inflammatory tumor-promoting activity of multiple myeloma-educated dendritic cells

scientific article published on 21 November 2017

MicroRNAs: Novel Crossroads between Myeloma Cells and the Bone Marrow Microenvironment

scientific article

Molecular targets for the treatment of multiple myeloma.

scientific article published on September 2012

Protein arginine methyltransferase 5 has prognostic relevance and is a druggable target in multiple myeloma

scientific article published on 21 November 2017

Selective targeting of IRF4 by synthetic microRNA-125b-5p mimics induces anti-multiple myeloma activity in vitro and in vivo.

scientific article

Synthetic miR-34a mimics as a novel therapeutic agent for multiple myeloma: in vitro and in vivo evidence.

scientific article published on 3 October 2012

Targeting histone deacetylase 3 (HDAC3) in the bone marrow microenvironment inhibits multiple myeloma proliferation by modulating exosomes and IL-6 trans-signaling

scientific article published on 29 May 2019

Targeting miR-21 inhibits in vitro and in vivo multiple myeloma cell growth

scientific article

The AP-1 transcription factor JunB is essential for multiple myeloma cell proliferation and drug resistance in the bone marrow microenvironment.

scientific article published on 28 November 2016

Therapeutic Targeting of miR-29b/HDAC4 Epigenetic Loop in Multiple Myeloma.

scientific article published on 18 May 2016

Therapeutic vulnerability of multiple myeloma to MIR17PTi, a first-in-class inhibitor of pri-miR-17-92

scientific article published on 11 July 2018

miR-22 suppresses DNA ligase III addiction in multiple myeloma

scientific article published on 17 August 2018

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