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List of works by Anthony R Green

A Detailed Physical and Transcriptional Map of the Region of Chromosome 20 That Is Deleted in Myeloproliferative Disorders and Refinement of the Common Deleted Region

scientific article published on 01 May 1998

A kinase-independent function of CDK6 links the cell cycle to tumor angiogenesis

scientific article

A novel mode of enhancer evolution: the Tal1 stem cell enhancer recruited a MIR element to specifically boost its activity

scientific article (publication date: September 2008)

A novel signalling screen demonstrates that CALR mutations activate essential MAPK signalling and facilitate megakaryocyte differentiation.

scientific article published on 14 October 2016

A screen of the complete protein kinase gene family identifies diverse patterns of somatic mutations in human breast cancer

scientific article published on 22 May 2005

Age and aging in blood disorders: EHA theme of the year 2013-2014.

scientific article published in June 2013

Analyses of the extent of shared synteny and conserved gene orders between the genome of Fugu rubripes and human 20q.

scientific article published on May 2002

Analysis of Jak2 signaling reveals resistance of mouse embryonic hematopoietic stem cells to myeloproliferative disease mutation.

scientific article published on 10 February 2016

Analysis of human leukaemias and lymphomas using extensive immunophenotypes from an antibody microarray.

scientific article published on 25 August 2006

Analysis of multiple genomic sequence alignments: a web resource, online tools, and lessons learned from analysis of mammalian SCL loci.

scientific article

BET protein inhibition shows efficacy against JAK2V617F-driven neoplasms

scientific article published on 9 August 2013

Bone marrow pathology in essential thrombocythemia: interobserver reliability and utility for identifying disease subtypes

scientific article (publication date: 2008)

CALR mutations in myeloproliferative neoplasms: hidden behind the reticulum.

scientific article published on 11 March 2014

Characterization of the imprinted polycomb gene L3MBTL, a candidate 20q tumour suppressor gene, in patients with myeloid malignancies

scientific article

Chromosome 20 deletions in myeloid malignancies: reduction of the common deleted region, generation of a PAC/BAC contig and identification of candidate genes

article

Chronic myeloproliferative diseases with and without the Ph chromosome: some unresolved issues.

scientific article published on 30 July 2009

Clinical and biological implications of driver mutations in myelodysplastic syndromes

scientific article published on 12 September 2013

Clinical utility of routine MPL exon 10 analysis in the diagnosis of essential thrombocythaemia and primary myelofibrosis.

scientific article published on 11 February 2010

Clonal analyses reveal associations of JAK2V617F homozygosity with hematologic features, age and gender in polycythemia vera and essential thrombocythemia ⬇️

scientific article published on May 1, 2013

Clonal heterogeneity as a driver of disease variability in the evolution of myeloproliferative neoplasms

scientific article published on 06 September 2014

Combined Single-Cell Functional and Gene Expression Analysis Resolves Heterogeneity within Stem Cell Populations

scientific article

Coming to grips with complex disorders: genetic risk prediction in bipolar disorder using panels of genes identified through convergent functional genomics

scientific article published on June 2010

Constitutive activation of JAK2 in mammary epithelium elevates Stat5 signalling, promotes alveologenesis and resistance to cell death, and contributes to tumourigenesis ⬇️

scientific article published on September 23, 2011

Cooperativity of imprinted genes inactivated by acquired chromosome 20q deletions ⬇️

scientific article published on April 2013

Correlation of blood counts with vascular complications in essential thrombocythemia: analysis of the prospective PT1 cohort ⬇️

scientific article published on June 18, 2012

Costs of haematological disease high and rising.

scientific article published on 22 July 2016

Cytokine-induced megakaryocytic differentiation is regulated by genome-wide loss of a uSTAT transcriptional program.

scientific article

DNMT3A mutations occur early or late in patients with myeloproliferative neoplasms and mutation order influences phenotype

scientific article published on 6 August 2015

Definition of subtypes of essential thrombocythaemia and relation to polycythaemia vera based on JAK2 V617F mutation status: a prospective study.

scientific article

Determination of complex subclonal structures of hematological malignancies by multiplexed genotyping of blood progenitor colonies

scientific article published on 9 October 2017

Determination of human neutrophil antigen‐1, ‐3, ‐4 and ‐5 allele frequencies in English Caucasoid blood donors using a multiplex fluorescent DNA‐based assay ⬇️

scientific article published on February 9, 2013

Diagnostic pathway for the investigation of thrombocytosis.

scientific article published on 11 March 2013

Directing oncogenic fusion genes into stem cells via an SCL enhancer

scientific article

Discordant regulation of SCL/TAL-1 mRNA and protein during erythroid differentiation.

scientific article published on July 1995

Distinct clinical phenotypes associated with JAK2V617F reflect differential STAT1 signaling

scientific article

Distinct mechanisms direct SCL/tal-1 expression in erythroid cells and CD34 positive primitive myeloid cells

scientific article published in March 1997

Double jeopardy from a single translocation: deletions of the derivative chromosome 9 in chronic myeloid leukemia.

scientific article

Effect of mutation order on myeloproliferative neoplasms

scientific article

Effect of mutation order on myeloproliferative neoplasms

scientific article published on 01 May 2015

Equivalence of BCSH and WHO diagnostic criteria for ET.

scientific article published on 29 November 2016

Essential thrombocythaemia

scientific article published on 01 January 2006

Establishing the transcriptional programme for blood: the SCL stem cell enhancer is regulated by a multiprotein complex containing Ets and GATA factors.

scientific article published on June 2002

Fli1, Elf1, and Ets1 regulate the proximal promoter of the LMO2 gene in endothelial cells.

scientific article published on 30 June 2005

Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells

scientific article published on 11 May 2015

Gata2, Fli1, and Scl form a recursively wired gene-regulatory circuit during early hematopoietic development

scientific journal article

Genetic variation at MECOM, TERT, JAK2 and HBS1L-MYB predisposes to myeloproliferative neoplasms

scientific article

Genetically tagging endothelial cells in vivo: bone marrow-derived cells do not contribute to tumor endothelium.

scientific article

Genome-wide analysis of simultaneous GATA1/2, RUNX1, FLI1, and SCL binding in megakaryocytes identifies hematopoietic regulators.

scientific article

Genome-wide association study of borderline personality disorder reveals genetic overlap with bipolar disorder, major depression and schizophrenia

scientific article published on 20 June 2017

Genome-wide identification of cis-regulatory sequences controlling blood and endothelial development.

scientific article published on 13 January 2005

Genome-wide linkage analysis of 972 bipolar pedigrees using single-nucleotide polymorphisms.

scientific article

Genomic imbalances in CML blast crisis: 8q24.12-q24.13 segment identified as a common region of over-representation.

scientific article published on August 2003

Genotype-phenotype interactions in the myeloproliferative neoplasms.

scientific article published on 28 August 2012

Guideline for investigation and management of adults and children presenting with a thrombocytosis

scientific article

Guideline for the diagnosis and management of myelofibrosis.

scientific article published in June 2012

Guidelines for the diagnosis, investigation and management of polycythaemia/erythrocytosis.

scientific article published in July 2005

How good a model is the Fugu genome?

scientific article published in Nature

Hoxa9 and Meis1 Cooperatively Induce Addiction to Syk Signaling by Suppressing miR-146a in Acute Myeloid Leukemia

scientific article

Hydroxycarbamide Plus Aspirin Versus Aspirin Alone in Patients With Essential Thrombocythemia Age 40 to 59 Years Without High-Risk Features

scientific article published on 28 August 2018

Hydroxyurea compared with anagrelide in high-risk essential thrombocythemia

scientific article (publication date: 7 July 2005)

ID1 promotes expansion and survival of primary erythroid cells and is a target of JAK2V617F-STAT5 signaling

scientific article published on July 2009

Identification of endoglin as a functional marker that defines long-term repopulating hematopoietic stem cells

scientific article published on 15 November 2002

Identifying gene regulatory elements by genomic microarray mapping of DNaseI hypersensitive sites

scientific article

Imatinib improves but may not fully reverse the poor prognosis of patients with CML with derivative chromosome 9 deletions.

scientific article published on 15 May 2003

Imprinting of the human L3MBTL gene, a polycomb family member located in a region of chromosome 20 deleted in human myeloid malignancies

scientific article

In vivo fate-tracing studies using the Scl stem cell enhancer: embryonic hematopoietic stem cells significantly contribute to adult hematopoiesis.

scientific article published on 14 December 2004

Inactivating CUX1 mutations promote tumorigenesis

scientific article

Independently acquired biallelic JAK2 mutations are present in a minority of patients with essential thrombocythemia.

scientific article

Inducible chronic phase of myeloid leukemia with expansion of hematopoietic stem cells in a transgenic model of BCR-ABL leukemogenesis.

scientific article published on 26 August 2004

International network of cancer genome projects

scientific article

JAK2 V617F impairs hematopoietic stem cell function in a conditional knock-in mouse model of JAK2 V617F-positive essential thrombocythemia

scientific article

JAK2 phosphorylates histone H3Y41 and excludes HP1alpha from chromatin

scientific article

JAK2V617F homozygosity drives a phenotypic switch in myeloproliferative neoplasms, but is insufficient to sustain disease

scientific article published in April 2014

JAK2V617F leads to intrinsic changes in platelet formation and reactivity in a knock-in mouse model of essential thrombocythemia

scientific article published on October 2013

JAK2V617F mediates resistance to DNA damage-induced apoptosis by modulating FOXO3A localization and Bcl-xL deamidation

scientific article published on 3 August 2015

JAK2V617F promotes replication fork stalling with disease-restricted impairment of the intra-S checkpoint response

scientific article

Janus kinase deregulation in leukemia and lymphoma

scientific article

Kidney, blood, and endothelium: developmental expression of stem cell leukemia during nephrogenesis.

scientific article published on April 2004

L3mbtl, the mouse orthologue of the imprinted L3MBTL, displays a complex pattern of alternative splicing and escapes genomic imprinting

scientific journal article

LIF-independent JAK signalling to chromatin in embryonic stem cells uncovered from an adult stem cell disease

scientific article

Lineage-restricted regulation of the murine SCL/TAL-1 promoter.

scientific article

Low-dose methotrexate in myeloproliferative neoplasm models

scientific article published on 26 May 2017

MARIMO cells harbor a CALR mutation but are not dependent on JAK2/STAT5 signaling

scientific article published on 24 September 2014

MEDULLOBLASTOMA

MPL mutations in myeloproliferative disorders: analysis of the PT-1 cohort.

scientific article

MPN-associated myelofibrosis (MPN-MF).

scientific article published on 4 August 2010

Manipulation of Mouse Hematopoietic Progenitors by Specific Retroviral Infection

scientific article published on 18 August 2003

Master regulator unmasked

scientific article published in Nature

Mbd3/NuRD controls lymphoid cell fate and inhibits tumorigenesis by repressing a B cell transcriptional program.

scientific article published on 12 September 2017

Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

scientific article

Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder.

scientific article

Methods for detecting mutations in the human JAK2 gene.

scientific article published in January 2013

Methylation of the suppressor of cytokine signaling 3 gene (SOCS3) in myeloproliferative disorders

scientific article published on 24 September 2008

MicroRNA-101 expression is associated with JAK2V617F activity and regulates JAK2/STAT5 signaling

scientific article published on 27 February 2018

Modification of British Committee for Standards in Haematology diagnostic criteria for essential thrombocythaemia

scientific article published on 17 June 2014

Molecular cytogenetics of polycythaemia vera: lack of occult rearrangements detectable by 20q LSP screening, CGH, and M-FISH

scientific article published on 01 July 2003

Molecular determinants of pathogenesis and clinical phenotype in myeloproliferative neoplasms

scientific article published on December 2016

Multiplexing for Oxidative Bisulfite Sequencing (oxBS-seq).

scientific article published in January 2018

Mutant calreticulin knock-in mice develop thrombocytosis and myelofibrosis without a stem cell self-renewal advantage

scientific article

Mutations of JAK2 in acute lymphoblastic leukaemias associated with Down's syndrome

scientific article published on 19 September 2008

Myeloproliferative disorders

scientific article published on 01 September 2001

Myeloproliferative neoplasms: from origins to outcomes.

scientific article published on 6 December 2017

Myeloproliferative neoplasms: from origins to outcomes.

scientific article published in December 2017

Nongenetic stochastic expansion of JAK2V617F-homozygous subclones in polycythemia vera?

scientific article published in November 2014

Not so NICE for CML.

scientific article

Nuclear JAK2.

scientific article published in December 2011

Order Matters: The Order of Somatic Mutations Influences Cancer Evolution

scientific article published on 17 January 2017

Origins and functional consequences of somatic mitochondrial DNA mutations in human cancer

scientific article

Pain from myelofibrosis treated with regular pamidronate.

scientific article published in November 2004

Pathogenesis and management of essential thrombocythemia.

scientific article

Pathogenesis of Myeloproliferative Disorders.

scientific article published on May 2016

Persistent STAT5 activation in myeloid neoplasms recruits p53 into gene regulation

scientific article published on 31 March 2014

Polygenic dissection of the bipolar phenotype

scientific article

Population dynamics of normal human blood inferred from somatic mutations

scientific article published in Nature

Progenitors homozygous for the V617F mutation occur in most patients with polycythemia vera, but not essential thrombocythemia.

scientific article published on 13 June 2006

Proliferation Drives Aging-Related Functional Decline in a Subpopulation of the Hematopoietic Stem Cell Compartment

scientific article published on May 2017

Quantification of PRV-1 mRNA distinguishes polycythemia vera from secondary erythrocytosis

scientific article published on 31 July 2003

RECQL5 Suppresses Oncogenic JAK2-Induced Replication Stress and Genomic Instability ⬇️

scientific article published on 9 December 2015

RFP represses transcriptional activation by bHLH transcription factors

scientific journal article

Randomized comparison of low-dose versus high-dose interferon-alfa in chronic myeloid leukemia: prospective collaboration of 3 joint trials by the MRC and HOVON groups

scientific article

Replication of bipolar disorder susceptibility alleles and identification of two novel genome-wide significant associations in a new bipolar disorder case-control sample

scientific article published on 16 October 2012

Retinoic acid and the differentiation of lymphohaemopoietic stem cells.

scientific article published on March 1995

Ruxolitinib-induced defects in DNA repair cause sensitivity to PARP inhibitors in myeloproliferative neoplasms.

scientific article published on 17 October 2017

SC3: consensus clustering of single-cell RNA-seq data

scientific article

SCL and related hemopoietic helix-loop-helix transcription factors

scientific article (publication date: September 1992)

SOCS3 tyrosine phosphorylation as a potential bio-marker for myeloproliferative neoplasms associated with mutant JAK2 kinases

scientific article published on 19 February 2009

Self-renewal of single mouse hematopoietic stem cells is reduced by JAK2V617F without compromising progenitor cell expansion

scientific article (publication date: 2013)

Single-cell approaches identify the molecular network driving malignant hematopoietic stem cell self-renewal

scientific article published on 10 July 2018

Solid phase PCR sequencing of biotinylated products

scientific article published on 01 January 1993

Somatic CALR mutations in myeloproliferative neoplasms with nonmutated JAK2

scientific article

Somatic SF3B1 mutation in myelodysplasia with ring sideroblasts

scientific article

Somatic mutations of the protein kinase gene family in human lung cancer

scientific article published on September 2005

TUMOUR BIOLOGY

Temporal regulation of Cre-recombinase activity in Scl-positive neurons of the central nervous system.

scientific article published in March 2007

The European Hematology Association Roadmap for European Hematology Research: a consensus document

scientific article

The JAK-STAT signaling pathway is differentially activated in CALR-positive compared with JAK2V617F-positive ET patients.

scientific article published on March 2015

The JAK2 46/1 haplotype predisposes to MPL-mutated myeloproliferative neoplasms

scientific article

The Ph-positive and Ph-negative myeloproliferative neoplasms: some topical pre-clinical and clinical issues

scientific article

The Philadelphia translocation and pre-existing myeloproliferative disorders.

scientific article

The SCL +40 enhancer targets the midbrain together with primitive and definitive hematopoiesis and is regulated by SCL and GATA proteins.

scientific article published on 20 August 2007

The SCL gene specifies haemangioblast development from early mesoderm.

scientific article published on July 1998

The SCL transcriptional network and BMP signaling pathway interact to regulate RUNX1 activity

scholarly article

The V617F JAK2 mutation is uncommon in cancers and in myeloid malignancies other than the classic myeloproliferative disorders

scientific article

The bipolar disorder risk allele at CACNA1C also confers risk of recurrent major depression and of schizophrenia

scientific article

The evolving genomic landscape of myeloproliferative neoplasms.

scientific article

The gene encoding hematopoietic cell phosphatase (SHP-1) is structurally and transcriptionally intact in polycythemia vera

article

The paralogous hematopoietic regulators Lyl1 and Scl are coregulated by Ets and GATA factors, but Lyl1 cannot rescue the early Scl-/- phenotype.

scientific article published on 19 October 2006

The pufferfish SLP-1 gene, a new member of the SCL/TAL-1 family of transcription factors.

scientific article published in February 1998

The stem/progenitor landscape is reshaped in a mouse model of essential thrombocythemia and causes excess megakaryocyte production

scientific article published on 25 November 2020

The transcription factors Scl and Lmo2 act together during development of the hemangioblast in zebrafish

scientific article published on 7 November 2006

The unfolded protein response governs integrity of the haematopoietic stem-cell pool during stress.

scientific article published on 28 April 2014

The use of granulocyte colony-stimulating factor in volunteer blood and marrow registry donors.

scientific article published on 25 September 2006

Three distinct patterns of histone H3Y41 phosphorylation mark active genes.

scientific article

Thrombopoietin signaling to chromatin elicits rapid and pervasive epigenome remodeling within poised chromatin architectures

scientific article published on 2 February 2018

Transcription factors and the regulation of haemopoiesis: lessons from GATA and SCL proteins.

scientific article published in July 1994

Transcription factors, translocations and haematological malignancies ⬇️

scientific article published on June 1, 1992

Transcription of the SCL gene in erythroid and CD34 positive primitive myeloid cells is controlled by a complex network of lineage-restricted chromatin-dependent and chromatin-independent regulatory elements.

scientific article published in November 1997

Transcriptional link between blood and bone: the stem cell leukemia gene and its +19 stem cell enhancer are active in bone cells

scientific article

Transcriptional regulation of the stem cell leukemia gene (SCL)--comparative analysis of five vertebrate SCL loci

scientific article

Transcriptional regulation of the stem cell leukemia gene by PU.1 and Elf-1.

scientific article

Transgenic analysis of the stem cell leukemia +19 stem cell enhancer in adult and embryonic hematopoietic and endothelial cells.

scientific article published on 28 July 2005

Two routes to leukemic transformation after a JAK2 mutation-positive myeloproliferative neoplasm.

scientific article published on 11 December 2009

Two unusual neurological presentations of granulocytic sarcoma in Philadelphia positive chronic myeloid leukaemia

scientific article published on 01 October 1994

Use of JAK inhibitors in the management of myelofibrosis: a revision of the British Committee for Standards in Haematology Guidelines for Investigation and Management of Myelofibrosis 2012.

scientific article published on 25 June 2014

cis-Regulatory remodeling of the SCL locus during vertebrate evolution.

scientific article published on 18 October 2010

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