List of works - Yazi D Ke

A decade of tau transgenic animal models and beyond

scientific article published on January 2007

ALS/FTLD: experimental models and reality

scientific article published on 5 January 2017

Adeno-associated virus-based Alzheimer's disease mouse models and potential new therapeutic avenues

scientific article published on 23 April 2019

Altered levels of PP2A regulatory B/PR55 isoforms indicate role in neuronal differentiation

scientific article published on 11 October 2006

An N-terminal motif unique to primate tau enables differential protein-protein interactions

scientific article

Aβ-dependent reduction of NCAM2-mediated synaptic adhesion contributes to synapse loss in Alzheimer's disease

scientific article

Brief update on different roles of tau in neurodegeneration

scientific article published on July 2011

CNS cell type-specific gene profiling of P301S tau transgenic mice identifies genes dysregulated by progressive tau accumulation

scientific article published on 31 July 2019

Cytoplasmic accumulation and aggregation of TDP-43 upon proteasome inhibition in cultured neurons

scientific article

Dendritic function of tau mediates amyloid-beta toxicity in Alzheimer's disease mouse models

scientific journal article

Developmental Expression of Mutant PFN1 in Motor Neurons Impacts Neuronal Growth and Motor Performance of Young and Adult Mice

scientific article published on 27 September 2019

Disinhibition-like behavior in a P301S mutant tau transgenic mouse model of frontotemporal dementia

scientific article published on 10 August 2016

Dissecting toxicity of tau and beta-amyloid

scientific article

ERK inhibition with PD184161 mitigates brain damage in a mouse model of stroke.

scientific article published on 14 December 2013

Epothilone D - correct drug, wrong disease

scientific article published on 13 February 2018

Experimental diabetes mellitus exacerbates tau pathology in a transgenic mouse model of Alzheimer's disease

scientific article

Functional genomics dissects pathomechanisms in tauopathies: mitosis failure and unfolded protein response

scientific article published on 06 March 2008

Generation of a New Tau Knockout (tauΔex1) Line Using CRISPR/Cas9 Genome Editing in Mice

scientific article published in January 2018

Mouse models of frontotemporal dementia: A comparison of phenotypes with clinical symptomatology

scientific article published on 11 January 2017

Neuronal microRNA deregulation in response to Alzheimer's disease amyloid-beta

scientific article

No Overt Deficits in Aged Tau-Deficient C57Bl/6.Mapttm1(EGFP)Kit GFP Knockin Mice

scientific article

Parkinsonism and impaired axonal transport in a mouse model of frontotemporal dementia

scholarly article

Peptide Nanofiber Substrates for Long-Term Culturing of Primary Neurons

article

Phosphorylated Tau interacts with c-Jun N-terminal kinase-interacting protein 1 (JIP1) in Alzheimer disease

scientific article published on 02 June 2009

Phosphorylation of soluble tau differs in Pick's disease and Alzheimer's disease brains

scientific article published on 20 August 2009

Primary support cultures of hippocampal and substantia nigra neurons

article

SARS-CoV-2 infection and viral fusogens cause neuronal and glial fusion that compromises neuronal activity

Selective spatio-temporal vulnerability of central nervous system neurons to pathological TAR DNA-binding protein 43 in aged transgenic mice.

scientific article published on 22 March 2018

Short-term suppression of A315T mutant human TDP-43 expression improves functional deficits in a novel inducible transgenic mouse model of FTLD-TDP and ALS.

scientific article published on 5 October 2015

Site-specific phosphorylation of tau inhibits amyloid-β toxicity in Alzheimer's mice

scientific article

Sodium selenate mitigates tau pathology, neurodegeneration, and functional deficits in Alzheimer's disease models

scientific article

TDP-43 mutations causing amyotrophic lateral sclerosis are associated with altered expression of RNA-binding protein hnRNP K and affect the Nrf2 antioxidant pathway.

scientific article

Tau downregulates BDNF expression in animal and cellular models of Alzheimer's disease

scientific article published on 31 August 2016

Tau exacerbates excitotoxic brain damage in an animal model of stroke

scientific article published on 7 September 2017

Tau-mediated nuclear depletion and cytoplasmic accumulation of SFPQ in Alzheimer's and Pick's disease

scientific article

Tau-targeted immunization impedes progression of neurofibrillary histopathology in aged P301L tau transgenic mice

scientific article

List of works by Yazi D Ke

A decade of tau transgenic animal models and beyond

ALS/FTLD: experimental models and reality

Adeno-associated virus-based Alzheimer's disease mouse models and potential new therapeutic avenues

Altered levels of PP2A regulatory B/PR55 isoforms indicate role in neuronal differentiation

An N-terminal motif unique to primate tau enables differential protein-protein interactions

Aβ-dependent reduction of NCAM2-mediated synaptic adhesion contributes to synapse loss in Alzheimer's disease

Brief update on different roles of tau in neurodegeneration

CNS cell type-specific gene profiling of P301S tau transgenic mice identifies genes dysregulated by progressive tau accumulation

Cytoplasmic accumulation and aggregation of TDP-43 upon proteasome inhibition in cultured neurons

Dendritic function of tau mediates amyloid-beta toxicity in Alzheimer's disease mouse models

Developmental Expression of Mutant PFN1 in Motor Neurons Impacts Neuronal Growth and Motor Performance of Young and Adult Mice

Disinhibition-like behavior in a P301S mutant tau transgenic mouse model of frontotemporal dementia

Dissecting toxicity of tau and beta-amyloid

ERK inhibition with PD184161 mitigates brain damage in a mouse model of stroke.

Epothilone D - correct drug, wrong disease

Experimental diabetes mellitus exacerbates tau pathology in a transgenic mouse model of Alzheimer's disease

Functional genomics dissects pathomechanisms in tauopathies: mitosis failure and unfolded protein response

Generation of a New Tau Knockout (tauΔex1) Line Using CRISPR/Cas9 Genome Editing in Mice

Mouse models of frontotemporal dementia: A comparison of phenotypes with clinical symptomatology

Neuronal microRNA deregulation in response to Alzheimer's disease amyloid-beta

No Overt Deficits in Aged Tau-Deficient C57Bl/6.Mapttm1(EGFP)Kit GFP Knockin Mice

Parkinsonism and impaired axonal transport in a mouse model of frontotemporal dementia

Peptide Nanofiber Substrates for Long-Term Culturing of Primary Neurons

Phosphorylated Tau interacts with c-Jun N-terminal kinase-interacting protein 1 (JIP1) in Alzheimer disease

Phosphorylation of soluble tau differs in Pick's disease and Alzheimer's disease brains

Primary support cultures of hippocampal and substantia nigra neurons

SARS-CoV-2 infection and viral fusogens cause neuronal and glial fusion that compromises neuronal activity

Selective spatio-temporal vulnerability of central nervous system neurons to pathological TAR DNA-binding protein 43 in aged transgenic mice.

Short-term suppression of A315T mutant human TDP-43 expression improves functional deficits in a novel inducible transgenic mouse model of FTLD-TDP and ALS.

Site-specific phosphorylation of tau inhibits amyloid-β toxicity in Alzheimer's mice

Sodium selenate mitigates tau pathology, neurodegeneration, and functional deficits in Alzheimer's disease models

TDP-43 mutations causing amyotrophic lateral sclerosis are associated with altered expression of RNA-binding protein hnRNP K and affect the Nrf2 antioxidant pathway.

Tau downregulates BDNF expression in animal and cellular models of Alzheimer's disease

Tau exacerbates excitotoxic brain damage in an animal model of stroke

Tau-mediated nuclear depletion and cytoplasmic accumulation of SFPQ in Alzheimer's and Pick's disease

Tau-targeted immunization impedes progression of neurofibrillary histopathology in aged P301L tau transgenic mice