Search filters

List of works by Joseph Lachance

A custom genotyping array reveals population-level heterogeneity for the genetic risks of prostate cancer and other cancers in Africa

scientific article published on 11 May 2020

A fundamental relationship between genotype frequencies and fitnesses

scientific article published on 09 September 2008

A recent bottleneck of Y chromosome diversity coincides with a global change in culture

scientific article

Apparent variation in Neanderthal admixture among African populations is consistent with gene flow from Non-African populations

scientific article (publication date: 2013)

Biased gene conversion skews allele frequencies in human populations, increasing the disease burden of recessive alleles

scientific article

Corrigendum: Model-based analyses of whole-genome data reveal a complex evolutionary history involving archaic introgression in Central African Pygmies

scientific article

Detecting selection-induced departures from Hardy-Weinberg proportions

scientific article published on 21 January 2009

Development, Evaluation, and Implementation of a Pan-African Cancer Research Network: Men of African Descent and Carcinoma of the Prostate

scholarly article

Disease-associated alleles in genome-wide association studies are enriched for derived low frequency alleles relative to HapMap and neutral expectations

scientific article

Evolutionary history and adaptation from high-coverage whole-genome sequences of diverse African hunter-gatherers

scientific article (publication date: 3 August 2012)

Evolving Antibiotics against Resistance: a Potential Platform for Natural Product Development?

scientific article published on 24 December 2019

Genetic disease risks can be misestimated across global populations

article published in 2018

Genetic hitchhiking and population bottlenecks contribute to prostate cancer disparities in men of African descent

scientific article published on 8 February 2018

Genomic analyses inform on migration events during the peopling of Eurasia

scientific article (publication date: 13 October 2016)

Hybrid fitness effects modify fixation probabilities of introgressed alleles

scientific article published in 2022

Inbreeding, pedigree size, and the most recent common ancestor of humanity

scientific article published on 11 August 2009

Long-term adaptation of epistatic genetic networks

scientific article published on 28 June 2008

Model-based analyses of whole-genome data reveal a complex evolutionary history involving archaic introgression in Central African Pygmies

scientific article

Population Genomics of Human Adaptation

scientific article

SNP ascertainment bias in population genetic analyses: Why it is important, and how to correct it ⬇️

scientific article published on 09 July 2013

Testing the generalizability of ancestry-specific polygenic risk scores to predict prostate cancer in sub-Saharan Africa

scientific article published in 2022

The Genomic Health of Ancient Hominins.

scientific article published in January 2017

The Population Genetics of X–Autosome Synthetic Lethals and Steriles ⬇️

scientific article published on September 6, 2011

The genetic prehistory of southern Africa

scientific article

The genetics of sex chromosomes: evolution and implications for hybrid incompatibility

scientific article

Whole-genome sequence analyses of Western Central African Pygmy hunter-gatherers reveal a complex demographic history and identify candidate genes under positive natural selection

scientific article

X-autosome incompatibilities in Drosophila melanogaster: tests of Haldane's rule and geographic patterns within species

scientific article

Paulina is supported by:

About Paulina

Help