List of works by Alain Filloux

A Cell-Free Biosensor for Detecting Quorum Sensing Molecules in P. aeruginosa-Infected Respiratory Samples.

scientific article published on 5 October 2017

A Pseudomonas aeruginosa TIR effector mediates immune evasion by targeting UBAP1 and TLR adaptors.

scientific article

A method to capture large DNA fragments from genomic DNA

scientific article published on 01 January 2014

A novel two-component system controls the expression of Pseudomonas aeruginosa fimbrial cup genes

scientific journal article

A visual assay to monitor T6SS-mediated bacterial competition.

scientific article published on 20 March 2013

Agrobacterium tumefaciens deploys a superfamily of type VI secretion DNase effectors as weapons for interbacterial competition in planta.

scientific article

An rhs gene linked to the second type VI secretion cluster is a feature of the Pseudomonas aeruginosa strain PA14.

scientific article published on 6 December 2013

Assembly of fimbrial structures in Pseudomonas aeruginosa: functionality and specificity of chaperone-usher machineries

scientific article published on 9 February 2007

Biofilm formation in Pseudomonas aeruginosa: fimbrial cup gene clusters are controlled by the transcriptional regulator MvaT

scientific journal article

Biofilms 2018: A diversity of microbes and mechanisms

scientific article published on 19 February 2019

Biofilms and Cyclic di-GMP (c-di-GMP) Signaling: Lessons from Pseudomonas aeruginosa and Other Bacteria

scientific article

Caenorhabditis elegans semi-automated liquid screen reveals a specialized role for the chemotaxis gene cheB2 in Pseudomonas aeruginosa virulence

scientific article

Causalities of war: The connection between type VI secretion system and microbiota

scientific article published on 12 January 2020

Characterization of a novel Zn²⁺-dependent intrinsic imipenemase from Pseudomonas aeruginosa

scientific journal article

Chemical analysis of cellular and extracellular carbohydrates of a biofilm-forming strain Pseudomonas aeruginosa PA14

scientific article

Coevolution of the ATPase ClpV, the sheath proteins TssB and TssC, and the accessory protein TagJ/HsiE1 distinguishes type VI secretion classes.

scientific article published on 10 October 2014

Complete Genome Sequence of Pseudomonas aeruginosa Reference Strain PAK

scientific article published on 10 October 2019

Contribution of Cyclic di-GMP in the Control of Type III and Type VI Secretion in Pseudomonas aeruginosa.

scientific article published on January 2017

Correction: The Diguanylate Cyclase HsbD Intersects with the HptB Regulatory Cascade to Control Pseudomonas aeruginosa Biofilm and Motility

scientific article published on 30 November 2016

Cross talk between type III secretion and flagellar assembly systems in Pseudomonas aeruginosa.

scientific article published on 16 February 2007

Crystal structure of the CupB6 adhesive tip from the chaperone-usher family of pili from Pseudomonas aeruginosa

scientific article

Current and future therapies for Pseudomonas aeruginosa infection in patients with cystic fibrosis.

scientific article published on August 2017

Cyclic di-GMP inactivates T6SS and T4SS activity in Agrobacterium tumefaciens

scientific article published on 04 June 2019

Cyclic-di-GMP regulates lipopolysaccharide modification and contributes to Pseudomonas aeruginosa immune evasion

scientific article published on 6 March 2017

Delivery of the Pseudomonas aeruginosa Phospholipase Effectors PldA and PldB in a VgrG- and H2-T6SS-Dependent Manner

scientific article published on 31 July 2019

Detection of Colistin Resistance in Escherichia coli by Use of the MALDI Biotyper Sirius Mass Spectrometry System

scientific article published on 22 November 2019

Detection of Colistin Resistance in Salmonella enterica Using MALDIxin Test on the Routine MALDI Biotyper Sirius Mass Spectrometer

scientific article published on 03 June 2020

Diguanylate cyclase DgcP is involved in plant and human Pseudomonas spp. infections

scientific article published on 25 March 2015

Direct detection of lipid A on intact Gram-negative bacteria by MALDI-TOF mass spectrometry

scientific article published on 3 December 2015

Distinct oligomeric forms of the Pseudomonas aeruginosa RetS sensor domain modulate accessibility to the ligand binding site

scientific article

Effectiveness of Pseudomonas aeruginosa type VI secretion system relies on toxin potency and type IV pili-dependent interaction

scientific article published in 2023

Emergence of secretion-defective sublines of Pseudomonas aeruginosa PAO1 resulting from spontaneous mutations in the vfr global regulatory gene

scientific journal article

Erratum: Corrigendum: The p110δ isoform of the kinase PI(3)K controls the subcellular compartmentalization of TLR4 signaling and protects from endotoxic shock

scholarly article by Ezra Aksoy et al published August 2013 in Nature Immunology

FppA, a novel Pseudomonas aeruginosa prepilin peptidase involved in assembly of type IVb pili

scientific journal article

Gene amplification and qRT-PCR.

scientific article published in January 2014

High-level antibiotic resistance in Pseudomonas aeruginosa biofilm: the ndvB gene is involved in the production of highly glycerol-phosphorylated beta-(1->3)-glucans, which bind aminoglycosides.

scientific article published on 26 March 2010

Higher Prevalence of PldA, a -Kingdom H2-Type VI Secretion System Effector, in Clinical Isolates Responsible for Acute Infections and in Multidrug Resistant Strains

scientific article published in 2018

Identification of Tse8 as a Type VI secretion system toxin from Pseudomonas aeruginosa that targets the bacterial transamidosome to inhibit protein synthesis in prey cells

scientific article published on 19 August 2021

Identification of XcpP domains that confer functionality and specificity to the Pseudomonas aeruginosa type II secretion apparatus

scientific article

Internalization of Pseudomonas aeruginosa Strain PAO1 into Epithelial Cells Is Promoted by Interaction of a T6SS Effector with the Microtubule Network

scientific article published on 2 June 2015

Key two-component regulatory systems that control biofilm formation in Pseudomonas aeruginosa

scientific article published on 09 May 2011

Lifestyle transitions and adaptive pathogenesis of Pseudomonas aeruginosa.

scientific article published on 18 November 2017

Looking inside an injection system

scientific article published on 17 September 2019

Manipulating the type VI secretion system spike to shuttle passenger proteins

scientific article published on 26 February 2020

Multiple Roles of c-di-GMP Signaling in Bacterial Pathogenesis

scientific article published on 01 September 2019

Multiple structures disclose the Secretins Secrets.

scientific article published on 20 December 2017

Optimization of the MALDIxin test for the rapid identification of colistin resistance in Klebsiella pneumoniae using MALDI-TOF MS

scientific article published on 01 January 2020

Organization and PprB-dependent control of the Pseudomonas aeruginosa tad Locus, involved in Flp pilus biology

scientific journal article

PAAR proteins act as the 'sorting hat' of the type VI secretion system

scientific article published on 01 November 2019

Pel is a cationic exopolysaccharide that cross-links extracellular DNA in the Pseudomonas aeruginosa biofilm matrix

scientific article

PelC is a Pseudomonas aeruginosa outer membrane lipoprotein of the OMA family of proteins involved in exopolysaccharide transport

scientific journal article

Pore-forming activity of the Pseudomonas aeruginosa type III secretion system translocon alters the host epigenome

scientific article

Probing the internal micromechanical properties of Pseudomonas aeruginosa biofilms by Brillouin imaging.

scientific article published on 8 September 2017

Professor Dieter Haas (1945-2017)

scientific article published on 14 August 2017

Protein secretion systems in Pseudomonas aeruginosa: A wealth of pathogenic weapons ⬇️

scientific article published on October 13, 2010

Pseudomonas aeruginosa infection in cystic fibrosis: pathophysiological mechanisms and therapeutic approaches

scientific article published on 13 May 2016

Pyoverdine-mediated iron uptake in Pseudomonas aeruginosa: the Tat system is required for PvdN but not for FpvA transport

scientific article

Quorum sensing negatively controls type III secretion regulon expression in Pseudomonas aeruginosa PAO1.

scientific article published on June 2005

Rapid detection and discrimination of chromosome- and MCR-plasmid-mediated resistance to polymyxins by MALDI-TOF MS in Escherichia coli: the MALDIxin test

scientific article published on 01 December 2018

Rapid detection of colistin resistance in Acinetobacter baumannii using MALDI-TOF-based lipidomics on intact bacteria

scientific article published in Scientific Reports

Regulatory RNAs and the HptB/RetS signalling pathways fine-tune Pseudomonas aeruginosa pathogenesis.

scientific article published on April 2010

Role of XcpP in the functionality of the Pseudomonas aeruginosa secreton

scientific article published on 01 September 2005

RsmA and AmrZ orchestrate the assembly of all three type VI secretion systems in Pseudomonas aeruginosa

scientific article published on 3 July 2017

Shigella-Induced Emergency Granulopoiesis Protects Zebrafish Larvae from Secondary Infection.

scientific article

Structure of ATP synthase from ESKAPE pathogen <i>Acinetobacter baumannii</i>

scientific article published on 16 February 2022

Structure of the Pseudomonas aeruginosa XcpT pseudopilin, a major component of the type II secretion system

scientific article

Structure-function analysis of HsiF, a gp25-like component of the type VI secretion system, in Pseudomonas aeruginosa

scientific article published on 26 August 2011

Structure-function analysis reveals that the Pseudomonas aeruginosa Tps4 two-partner secretion system is involved in CupB5 translocation

scientific article

Subcomplexes from the Xcp secretion system of Pseudomonas aeruginosa

scientific journal article

Subinhibitory concentration of kanamycin induces the Pseudomonas aeruginosa type VI secretion system

scientific article

TagF-mediated repression of bacterial type VI secretion systems involves a direct interaction with the cytoplasmic protein Fha.

scientific article published on 29 March 2018

The C-terminal amphipathic alpha-helix of Pseudomonas aeruginosa PelC outer membrane protein is required for its function

scientific article

The Diguanylate Cyclase HsbD Intersects with the HptB Regulatory Cascade to Control Pseudomonas aeruginosa Biofilm and Motility

scientific article

The HsiB1C1 (TssB-TssC) complex of the Pseudomonas aeruginosa type VI secretion system forms a bacteriophage tail sheathlike structure

scientific article published on 22 January 2013

The Hybrid Histidine Kinase LadS Forms a Multicomponent Signal Transduction System with the GacS/GacA Two-Component System in Pseudomonas aeruginosa

scientific article published on 13 May 2016

The Pseudomonas aeruginosa T6SS Delivers a Periplasmic Toxin that Disrupts Bacterial Cell Morphology

scientific article published on 01 October 2019

The Pseudomonas aeruginosa T6SS-VgrG1b spike is topped by a PAAR protein eliciting DNA damage to bacterial competitors.

scientific article published on 19 November 2018

The Pseudomonas aeruginosa reference strain PA14 displays increased virulence due to a mutation in ladS.

scientific article

The Pseudomonas aeruginosa sensor RetS switches type III and type VI secretion via c-di-GMP signalling

scientific article published on 29 September 2011

The Pseudomonas putida T6SS is a plant warden against phytopathogens

scientific article

The VgrG proteins are "à la carte" delivery systems for bacterial type VI effectors

scientific journal article

The absence of the Pseudomonas aeruginosa OprF protein leads to increased biofilm formation through variation in c-di-GMP level

scientific article published on 23 June 2015

The archetype Pseudomonas aeruginosa proteins TssB and TagJ form a novel subcomplex in the bacterial type VI secretion system.

scientific article published on 29 August 2012

The diguanylate cyclase SadC is a central player in Gac/Rsm-mediated biofilm formation in Pseudomonas aeruginosa.

scientific article

The p110δ isoform of the kinase PI(3)K controls the subcellular compartmentalization of TLR4 signaling and protects from endotoxic shock.

scientific article

The pel genes of the Pseudomonas aeruginosa PAK strain are involved at early and late stages of biofilm formation.

scientific article published in March 2005

The second type VI secretion system of Pseudomonas aeruginosa strain PAO1 is regulated by quorum sensing and Fur and modulates internalization in epithelial cells

scientific article

TssA forms a gp6-like ring attached to the type VI secretion sheath

scientific journal article

Two-component regulatory systems in Pseudomonas aeruginosa: an intricate network mediating fimbrial and efflux pump gene expression

scientific journal article

Type II Protein Secretion in Pseudomonas aeruginosa : the Pseudopilus Is a Multifibrillar and Adhesive Structure ⬇️

scientific article published on May 1, 2003

Type II-dependent secretion of a Pseudomonas aeruginosa DING protein

scientific journal article

Type VI secretion and anti-host effectors

scientific article published on 23 December 2015

Type VI secretion system in Pseudomonas aeruginosa: secretion and multimerization of VgrG proteins

scientific journal article

Visualizing Antimicrobials in Bacterial Biofilms: Three-Dimensional Biochemical Imaging Using TOF-SIMS.

scientific article

XphA/XqhA, a novel GspCD subunit for type II secretion in Pseudomonas aeruginosa

scientific journal article

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