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List of works by Mary C Farach-Carson

1,25 dihydroxyvitamin D(3) activates sphingomyelin turnover in ROS17/2.8 osteosarcoma cells without sphingolipid-induced changes in cytosolic Ca(2+)

scientific article published on 01 June 2000

1,25(OH)2-vitamin D3, a steroid hormone that produces biologic effects via both genomic and nongenomic pathways

scientific article published on March 1, 1992

A 3D in vitro model of patient-derived prostate cancer xenograft for controlled interrogation of in vivo tumor-stromal interactions.

scientific article

A control engineering approach to understanding the TGF-β paradox in cancer.

scientific article

A hydrogel-based tumor model for the evaluation of nanoparticle-based cancer therapeutics.

scientific article published on 18 January 2014

A promoter-level mammalian expression atlas

scientific article

Artificial Induction of Native Aquaporin-1 Expression in Human Salivary Cells

scientific article published on January 2017

Assay of direct effect of 1,25-dihydroxyvitamin D3 on calcium ion influx into cultured osteoblasts.

scientific article published on January 1997

Association of the α(2)δ(1) subunit with Ca(v)3.2 enhances membrane expression and regulates mechanically induced ATP release in MLO-Y4 osteocytes.

scientific article published on September 2011

Attachment, proliferation, and migration of marrow stromal osteoblasts cultured on biomimetic hydrogels modified with an osteopontin-derived peptide.

scientific article published on February 2004

Bioactive analogs that simulate subsets of biological activities of 1alpha,25(OH)(2)D(3) in osteoblasts.

scientific article

Biofunctionalization of electrospun PCL-based scaffolds with perlecan domain IV peptide to create a 3-D pharmacokinetic cancer model.

scientific article

Biomaterials-based strategies for salivary gland tissue regeneration

scientific article published on 15 February 2016

Border patrol: insights into the unique role of perlecan/heparan sulfate proteoglycan 2 at cell and tissue borders

scientific article published on 31 August 2013

Bottom-up assembly of salivary gland microtissues for assessing myoepithelial cell function.

scientific article published on 14 July 2017

Cabozantinib Reverses Renal Cell Carcinoma-Mediated Osteoblast Inhibition in Three-Dimensional Co-culture In Vitro and Reduces Bone Osteolysis In Vivo

scientific article published on 27 March 2020

Calcium signals in prostate cancer cells: specific activation by bone-matrix proteins

scientific article published on 01 January 2000

Chaperone properties of pdia3 participate in rapid membrane actions of 1α,25-dihydroxyvitamin d3

scientific article published on 9 May 2013

Chondrogenic differentiation on perlecan domain I, collagen II, and bone morphogenetic protein-2-based matrices.

scientific article published on July 2006

Co-culture of osteocytes and neurons on a unique patterned surface.

scientific article published on December 2011

Coating electrospun collagen and gelatin fibers with perlecan domain I for increased growth factor binding.

scientific article

Comparison of 6-s-cis- and 6-s-trans-locked analogs of 1alpha,25-dihydroxyvitamin D3 indicates that the 6-s-cis conformation is preferred for rapid nongenomic biological responses and that neither 6-s-cis- nor 6-s-trans-locked analogs are preferred

scientific article published on 01 September 1997

Conditional disruption of calcineurin B1 in osteoblasts increases bone formation and reduces bone resorption.

scientific article published on 19 September 2007

Correction: Perlecan/HSPG2 and matrilysin/MMP-7 as indices of tissue invasion: tissue localization and circulating perlecan fragments in a cohort of 288 radical prostatectomy patients.

scientific article published on September 2016

Decidual heparanase activity is increased during pregnancy in the baboon (Papio anubis) and in in vitro decidualization of human stromal cells.

scientific article

Deficiency in perlecan/HSPG2 during bone development enhances osteogenesis and decreases quality of adult bone in mice

scientific article

Developmental expression of a 53 KD dentin sialoprotein in rat tooth organs.

scientific article published on March 1992

Differentiation-induced loss of heparan sulfate in human exostosis derived chondrocytes

scientific article published on 01 June 2005

Dual 1,25-dihydroxyvitamin D3 signal response pathways in osteoblasts: Cross-talk between genomic and membrane-initiated pathways

scientific article published on April 1, 1998

Dynamic interactions between L-type voltage-sensitive calcium channel Cav1.2 subunits and ahnak in osteoblastic cells.

scientific article published on 04 March 2009

Effect of agents used in perforation repair on osteoblastic cells

scientific article published on 01 March 1997

Effects of Sphingosine Derivatives on MC3T3-E1 Preosteoblasts: Psychosine Elicits Release of Calcium from Intracellular Stores

scientific article published on September 14, 1995

Evidence for the formation of a complex between osteopontin and osteocalcin

scientific article published on 01 August 1992

Evidence that a non-RGD domain in rat osteopontin is involved in cell attachment

scientific article published on 01 December 1993

Evolution of the perlecan/HSPG2 gene and its activation in regenerating Nematostella vectensis

scientific article published on 15 April 2015

Expression of the heparan sulfate proteoglycan, perlecan, during mouse embryogenesis and perlecan chondrogenic activity in vitro

scientific article

Expression of voltage sensitive calcium channel (VSCC) L-type Cav1.2 (alpha1C) and T-type Cav3.2 (alpha1H) subunits during mouse bone development.

scientific article

FANTOM5 CAGE profiles of human and mouse samples

scientific article published on 29 August 2017

Fiber diameters control osteoblastic cell migration and differentiation in electrospun gelatin.

scientific article published on September 2010

Gabapentin Disrupts Binding of Perlecan to the α2δ1 Voltage Sensitive Calcium Channel Subunit and Impairs Skeletal Mechanosensation

scientific article published in 2022

HIP/RPL29 antagonizes VEGF and FGF2 stimulated angiogenesis by interfering with HS-dependent responses.

scientific article published in December 2008

Heparan sulfate interacting protein (HIP/L29) negatively regulates growth responses to basic fibroblast growth factor in gingival fibroblasts

scientific article published on 01 April 2002

Heparan sulfate proteoglycans: key players in cartilage biology.

scientific article

Heparanase expression and activity influences chondrogenic and osteogenic processes during endochondral bone formation

scientific article

Heparanase expression and function during early pregnancy in mice.

scientific article published on 16 May 2007

Heralding a new paradigm in 3D tumor modeling

scientific article published on 2 September 2016

Hierarchically structured, hyaluronic acid-based hydrogel matrices via the covalent integration of microgels into macroscopic networks.

scientific article published on June 2010

High extracellular calcium attenuates adipogenesis in 3T3-L1 preadipocytes.

scientific article published on December 2004

Hyaluronan: a simple polysaccharide with diverse biological functions.

scientific article published on 18 December 2013

Hyaluronic acid-based hydrogels as 3D matrices for in vitro evaluation of chemotherapeutic drugs using poorly adherent prostate cancer cells.

scientific article published on 19 August 2009

Hyaluronic acid-based hydrogels: from a natural polysaccharide to complex networks

scientific article published on January 1, 2012

Hydrogel-based 3D model of patient-derived prostate xenograft tumors suitable for drug screening

scientific article

Hypoxia increases VEGF-A production by prostate cancer and bone marrow stromal cells and initiates paracrine activation of bone marrow endothelial cells.

scientific article published on 07 July 2006

IL-1β induces p62/SQSTM1 and represses androgen receptor expression in prostate cancer cells

scientific article

Identification and characterization of 1,25D3-membrane-associated rapid response, steroid (1,25D3-MARRS)-binding protein in rat IEC-6 cells

scientific journal article

Identification of the rat bone 60K acidic glycoprotein as alpha 2HS-glycoprotein

scientific article published on 01 April 1991

Immunolocalization of osteopontin, osteocalcin, and dentin sialoprotein during dental root formation and early cementogenesis in the rat

scientific article published on 01 June 1994

Implantable three-dimensional salivary spheroid assemblies demonstrate fluid and protein secretory responses to neurotransmitters.

scientific article published on 10 May 2013

Improved binding of acidic bone matrix proteins to cationized filters during solid phase assays

scientific article published on 01 January 1992

Improved immunohistochemical staining of osteopontin (OPN) in paraffin-embedded archival bone specimens following antigen retrieval: anti-human OPN antibody recognizes multiple molecular forms.

scientific article published on April 1997

Inflammatory breast cancer: a model for investigating cluster-based dissemination.

scientific article

Involvement of 1,25D3-MARRS (membrane associated, rapid response steroid-binding), a novel vitamin D receptor, in growth inhibition of breast cancer cells.

scientific article

Lumen formation in three-dimensional cultures of salivary acinar cells.

scientific article

Matrilysin/MMP-7 Cleavage of Perlecan/HSPG2 Complexed with Semaphorin 3A Supports FAK-Mediated Stromal Invasion by Prostate Cancer Cells.

scientific article

Matrilysin/matrix metalloproteinase-7(MMP7) cleavage of perlecan/HSPG2 creates a molecular switch to alter prostate cancer cell behavior

scientific article published on 14 May 2014

Mecp2 deficiency decreases bone formation and reduces bone volume in a rodent model of Rett syndrome.

scientific article published on 03 May 2009

Medical and Dental Electronic Health Record Reporting Discrepancies in Integrated Patient Care

scientific article published on 27 September 2019

Membrane receptors for steroid hormones: a case for specific cell surface binding sites for vitamin D metabolites and estrogens.

scientific article

Membrane receptors for vitamin D steroid hormones: potential new drug targets.

scientific article

Microfabricated electrospun collagen membranes for 3-D cancer models and drug screening applications.

scientific article published on August 2009

Mining the extracellular matrix for tissue engineering applications.

scientific article

Modular Proteoglycan Perlecan/: Mutations, Phenotypes, and Functions

article

Modulation of osteopontin post-translational state by 1, 25-(OH)2-vitamin D3. Dependence on Ca2+ influx.

scientific article published on November 1998

Multilayered, Hyaluronic Acid-Based Hydrogel Formulations Suitable for Automated 3D High Throughput Drug Screening of Cancer-Stromal Cell Cocultures.

scientific article

Neuronal Trans-Differentiation in Prostate Cancer Cells.

scientific article published on 12 July 2016

Nongenomic actions of 1,25-dihydroxyvitamin D3 in rat osteosarcoma cells: structure-function studies using ligand analogs

scientific article published on 01 October 1991

Novel surface expression of reticulocalbin 1 on bone endothelial cells and human prostate cancer cells is regulated by TNF-alpha.

scientific article

Nuclear translocation of the 1,25D3-MARRS (membrane associated rapid response to steroids) receptor protein and NFkappaB in differentiating NB4 leukemia cells.

scientific article published on 11 January 2010

Osteoblast Ca(2+) permeability and voltage-sensitive Ca(2+) channel expression is temporally regulated by 1,25-dihydroxyvitamin D(3).

scientific article published on 12 October 2005

Osteoprotegerin expression and secretion are regulated by calcium influx through the L-type voltage-sensitive calcium channel

scientific article (publication date: 2004)

Paracrine factors produced by bone marrow stromal cells induce apoptosis and neuroendocrine differentiation in prostate cancer cells

scientific article published on February 1, 2011

Parathyroid hormone-stimulated resorption in calvaria cultured in serum-free medium is enhanced by the calcium-mobilizing activity of 1,25-dihydroxyvitamin D(3).

scientific article

Perlecan domain I gradients establish stable biomimetic heparin binding growth factor gradients for cell migration in hydrogels

scientific article published on 24 July 2019

Perlecan domain I promotes fibroblast growth factor 2 delivery in collagen I fibril scaffolds.

scientific article published on January 2005

Perlecan domain IV peptide stimulates salivary gland cell assembly in vitro

scientific article

Perlecan functions in chondrogenesis: insights from in vitro and in vivo models

scientific article (publication date: 2004)

Perlecan--a multifunctional extracellular proteoglycan scaffold.

scientific article published on 18 April 2007

Perlecan-containing pericellular matrix regulates solute transport and mechanosensing within the osteocyte lacunar-canalicular system.

scientific article published on April 2014

Perlecan/HSPG2 and matrilysin/MMP-7 as indices of tissue invasion: tissue localization and circulating perlecan fragments in a cohort of 288 radical prostatectomy patients

scientific article published on 04 February 2016

Perlecan/HSPG2: Signaling role of domain IV in chondrocyte clustering with implications for Schwartz‐Jampel Syndrome

scientific article published on 11 September 2018

Perlecan/Hspg2 deficiency alters the pericellular space of the lacunocanalicular system surrounding osteocytic processes in cortical bone.

scientific article published on March 2011

Primary Salivary Human Stem/Progenitor Cells Undergo Microenvironment-Driven Acinar-Like Differentiation in Hyaluronate Hydrogel Culture.

scientific article

Prostate cancer and neuroendocrine differentiation: more neuronal, less endocrine?

scientific article

RANK- and c-Met-mediated signal network promotes prostate cancer metastatic colonization

scientific article published on 04 March 2014

Rapamycin selectively reduces the association of transcripts containing complex 5' UTRs with ribosomes in C4-2B prostate cancer cells.

scientific article

Rational design of vitamin D3 analogues which selectively restore activity to a vitamin D receptor mutant associated with rickets.

scientific article published on October 2002

Reassembly of Functional Human Stem/Progenitor Cells in 3D Culture

scientific article published on 01 January 2018

Recreating the tumor microenvironment in a bilayer, hyaluronic acid hydrogel construct for the growth of prostate cancer spheroids

scientific article

Regulation of expression of 1,25D3-MARRS/ERp57/PDIA3 in rat IEC-6 cells by TGF beta and 1,25(OH)2D3.

scientific article published on 26 December 2006

Retracted: Improved Cellular Specificity of Plasmonic Nanobubbles versus Nanoparticles in Heterogeneous Cell Systems

retracted article

Retraction of "Tunable Plasmonic Nanoprobes for Theranostics of Prostate Cancer".

scientific article published on 7 January 2017

Ribozyme ablation demonstrates that the cardiac subtype of the voltage-sensitive calcium channel is the molecular transducer of 1, 25-dihydroxyvitamin D(3)-stimulated calcium influx in osteoblastic cells

scientific article published on 01 March 2000

Ribozyme knockdown functionally links a 1,25(OH)2D3 membrane binding protein (1,25D3-MARRS) and phosphate uptake in intestinal cells.

scientific article

Ribozyme-mediated reduction of wild-type and mutant cartilage oligomeric matrix protein (COMP) mRNA and protein

scientific article published on 23 February 2009

Rodent osteoblastic cells express voltage-sensitive calcium channels lacking a gamma subunit.

scientific article published on 10 September 2003

Sex Differences and Bone Metastases of Breast, Lung, and Prostate Cancers: Do Bone Homing Cancers Favor Feminized Bone Marrow?

scientific article published on 7 August 2017

Single molecule force measurements of perlecan/HSPG2: A key component of the osteocyte pericellular matrix

scientific article published on 4 November 2015

Spatiotemporal distribution of heparan sulfate epitopes during murine cartilage growth plate development

scientific article

Steroid hormone interactions with target cells: cross talk between membrane and nuclear pathways.

scientific article published on 8 October 2003

Structure-based design of selective agonists for a rickets-associated mutant of the vitamin d receptor.

scientific article

Systematic Analysis of Actively Transcribed Core Matrisome Genes Across Tissues and Cell Phenotypes

scientific article published in 2022

TISSUE ENGINEERING PERFUSABLE CANCER MODELS.

scientific article published on February 2014

Target gene activation by 1,25-dihydroxyvitamin D3 in osteosarcoma cells is independent of calcium influx

scientific article published on 01 December 1994

Three-dimensional (3D) culture of bone-derived human 786-O renal cell carcinoma retains relevant clinical characteristics of bone metastases.

scientific article published on 21 May 2015

Three-dimensional in vitro tumor models for cancer research and drug evaluation.

scientific article

Transcriptional activation by NFκB increases perlecan/HSPG2 expression in the desmoplastic prostate tumor microenvironment

scientific article

Tumor necrosis factor‐α treatment of HepG2 cells mobilizes a cytoplasmic pool of ERp57/1,25D3‐MARRS to the nucleus

scientific article published on September 1, 2011

Tuning Hydrogel Properties to Promote the Assembly of Salivary Gland Spheroids in 3D.

scientific article published on 18 October 2016

Ultrahigh-throughput Generation and Characterization of Cellular Aggregates in Laser-ablated Microwells of Poly(dimethylsiloxane).

scientific article

Ultrastructural immunolocalization of noncollagenous (osteopontin and osteocalcin) and plasma (albumin and alpha 2HS-glycoprotein) proteins in rat bone

scientific article published on 01 April 1993

Voltage-sensitive calcium channels in osteoblasts: mediators of plasma membrane signalling events.

scientific article published on January 1996

p62/SQSTM1 is required for cell survival of apoptosis-resistant bone metastatic prostate cancer cell lines.

scientific article published on 30 September 2013