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List of works by Motohiro Okada

A Working Hypothesis Regarding Identical Pathomechanisms between Clinical Efficacy and Adverse Reaction of Clozapine via the Activation of Connexin43

scientific article published on 24 September 2020

A de novo KCNQ2 mutation detected in non-familial benign neonatal convulsions.

scientific article

A functional near-infrared spectroscopy study on the basic word order in Japanese

scientific article published on 01 June 2008

Activation of Astroglial Connexin is Involved in Concentration-Dependent Double-Edged Sword Clinical Action of Clozapine

scientific article published on 11 February 2020

Age-Dependent and Sleep/Seizure-Induced Pathomechanisms of Autosomal Dominant Sleep-Related Hypermotor Epilepsy

scientific article published on 30 October 2020

Amantadine Combines Astroglial System Xc- Activation with Glutamate/NMDA Receptor Inhibition.

scientific article published on 17 May 2019

Amantadine Improves Delayed Neuropsychiatric Sequelae of Carbon Monoxide Poisoning: A Case Report

scientific article published on 25 October 2019

An event-related fNIRS investigation of Japanese word order.

scientific article published on 25 December 2009

Analysing regional unemployment rates, GDP per capita and financial support for regional suicide prevention programme on suicide mortality in Japan using governmental statistical data

scientific article published on 27 August 2020

Are some idiopathic epilepsies disorders of ion channels?: A working hypothesis.

scientific article

Associations between psychotic-like experiences and mental health status and other psychopathologies among Japanese early teens.

scientific article published on 8 January 2008

Astroglial Connexin43 as a Potential Target for a Mood Stabiliser

scientific article published on 30 December 2020

Asymmetry of prefrontal cortex activities and catechol-O-methyltransferase Val158Met genotype in patients with panic disorder during a verbal fluency task: near-infrared spectroscopy study.

scientific article published on 21 January 2009

Biphasic actions of topiramate on monoamine exocytosis associated with both soluble N-ethylmaleimide-sensitive factor attachment protein receptors and Ca(2+)-induced Ca(2+)-releasing systems.

scientific article published in January 2005

Both 3,4-dihydroxyphenylalanine and dopamine releases are regulated by Ca2+-induced Ca2+ releasing system in rat striatum.

scientific article

Can Financial Support Reduce Suicide Mortality Rates?

scientific article published on 29 November 2019

Candidate Strategies for Development of a Rapid-Acting Antidepressant Class That Does Not Result in Neuropsychiatric Adverse Effects: Prevention of Ketamine-Induced Neuropsychiatric Adverse Reactions

scientific article published on 26 October 2020

Carbamazepine Attenuates Astroglial L-Glutamate Release Induced by Pro-Inflammatory Cytokines via Chronically Activation of Adenosine A2A Receptor

scientific article published on 30 July 2019

Clozapine, but not haloperidol, enhances glial D-serine and L-glutamate release in rat frontal cortex and primary cultured astrocytes

scientific article

Combination Therapy of Zonisamide With Aripiprazole on ECT- and Benzodiazepine-Resistant Periodic Catatonia ⬇️

scientific article published on 01 January 2012

Congenital malformations due to antiepileptic drugs

scientific article published in February 1999

Cystine/Glutamate Antiporter and Aripiprazole Compensate NMDA Antagonist-Induced Dysfunction of Thalamocortical L-Glutamatergic Transmission ⬇️

article

Defective function of GABA-containing synaptic vesicles in mice lacking the AP-3B clathrin adaptor.

scientific article

Determination of exocytosis mechanisms of DOPA in rat striatum using in vivo microdialysis.

scientific article

Determination of genomic breakpoints in an epileptic patient using genotyping array

scientific article published on 19 January 2006

Determination of the effects of caffeine and carbamazepine on striatal dopamine release by in vivo microdialysis.

scientific article published in February 1997

Different actions for acute and chronic administration of mirtazapine on serotonergic transmission associated with raphe nuclei and their innervation cortical regions.

scientific article

Dopamine D2 and serotonin 5-HT1A receptors mediate the actions of aripiprazole in mesocortical and mesoaccumbens transmission.

scientific article published on 10 September 2011

Dysfunction of M-channel enhances propagation of neuronal excitability in rat hippocampus monitored by multielectrode dish and microdialysis systems.

scientific article

Effect of novel atypical antipsychotic, blonanserin, on extracellular neurotransmitter level in rat prefrontal cortex

scientific article published on 11 December 2010

Effects of Carbamazepine, Lacosamide and Zonisamide on Gliotransmitter Release Associated with Activated Astroglial Hemichannels

scientific article published on 05 June 2020

Effects of Financial Expenditure of Prefectures/Municipalities on Regional Suicide Mortality in Japan

scientific article published on 17 August 2021

Effects of Magnitude of Leading Stimulus on Prepulse Inhibition of Auditory Evoked Cerebral Responses: An Exploratory Study

scientific article published in 2021

Effects of carbamazepine on acetylcholine release and metabolism

scientific article published on 01 July 2000

Effects of carbamazepine on hippocampal serotonergic system ⬇️

scientific article published on August 1, 1998

Effects of levetiracetam on astroglial release of kynurenine-pathway metabolites

scientific article published on 06 October 2018

Effects of ryanodine receptor activation on neurotransmitter release and neuronal cell death following kainic acid-induced status epilepticus.

scientific article published on June 2005

Effects of valproate on neurotransmission associated with ryanodine receptors.

scientific article published on 9 September 2010

Effects of zonisamide on dopaminergic system

scientific article published on 01 November 1995

Effects of zonisamide on extracellular levels of monoamine and its metabolite, and on Ca2+ dependent dopamine release

scientific article published on November 1, 1992

Enhanced L-β-Aminoisobutyric Acid Is Involved in the Pathophysiology of Effectiveness for Treatment-Resistant Schizophrenia and Adverse Reactions of Clozapine

scientific article published in 2023

Factors responsible for the prolongation of school refusal.

scientific article published in August 1999

Genetic abnormalities underlying familial epilepsy syndromes.

scientific article

Genetic identifiers of epilepsy.

scientific article

Genetics of epilepsy: current status and perspectives.

scientific article

Hyperpolarization-activated cyclic nucleotide gated channels: a potential molecular link between epileptic seizures and Aβ generation in Alzheimer's disease

scientific article

Impacts of Dual-Income Household Rate on Suicide Mortalities in Japan

scientific article published on 26 May 2021

Improved accuracy of diagnosis of lumbar intra and/or extra-foraminal stenosis by use of three-dimensional MR imaging: comparison with conventional MR imaging

scientific article published on 11 December 2014

Incidence and Risk Factors of Postoperative Delirium following Pancreatic Surgery: Does the Administration of TJ-54 Reduce the Incidence of Delirium

scientific article

Interaction between Mesocortical and Mesothalamic Catecholaminergic Transmissions Associated with NMDA Receptor in the Locus Coeruleus

scientific article published on 01 July 2020

Interaction between carbamazepine, zonisamide and voltage-sensitive Ca2+ channel on acetylcholine release in rat frontal cortex.

scientific article

Knockdown of Cav2.1 calcium channels is sufficient to induce neurological disorders observed in natural occurring Cacna1a mutants in mice

scientific article published on 23 October 2009

Lamotrigine-induced neuroleptic malignant syndrome under risperidone treatment: a case report.

scientific article

Levetiracetam inhibits neurotransmitter release associated with CICR.

scientific article

Magnesium ion augmentation of inhibitory effects of adenosine on dopamine release in the rat striatum

scientific article published on 01 June 1996

Marital status of patients with epilepsy with special reference to the influence of epileptic seizures on the patient's married life.

scientific article published in January 2004

Memantine protects thalamocortical hyper-glutamatergic transmission induced by NMDA receptor antagonism via activation of system xc

scientific article published on 07 January 2019

Memantine protects thalamocortical hyper-glutamatergic transmission induced by NMDA receptor antagonism via activation of system xc<sup/>

Memory-based pre-attentive auditory N1 elicited by sound movement ⬇️

scientific article published on April 15, 2012

Mutation screening of AP3M2 in Japanese epilepsy patients.

scientific article published on 12 February 2007

Mutational analysis of GABRG2 in a Japanese cohort with childhood epilepsies.

scientific article published on 20 May 2010

Neuroleptic malignant syndrome induced by blonanserin

scientific article published on 01 January 2011

Novel δ1-receptor agonist KNT-127 increases the release of dopamine and L-glutamate in the striatum, nucleus accumbens and median pre-frontal cortex.

scientific article published on 17 January 2012

ONO-2506 inhibits spike-wave discharges in a genetic animal model without affecting traditional convulsive tests via gliotransmission regulation.

scientific article published on March 2013

Observations in the diagnosis of cervical myelopathy in patients suffering from diabetes mellitus ⬇️

scientific article published on May 15, 2012

Pathogenesis and pathophysiology of autosomal dominant sleep-related hypermotor epilepsy with S284L-mutant α4 subunit of nicotinic ACh receptor

scientific article published on 03 January 2020

Pharmacological discrimination of protein kinase associated exocytosis mechanisms between dopamine and 3,4-dihydroxyphenylalanine in rat striatum using in vivo microdialysis.

scientific article published on June 2004

Physical and psychomotor development in the offspring born to mothers with epilepsy.

scientific article published in January 2004

Prognosis and clinical features of intractable epilepsy: A prospective study ⬇️

scientific article published on August 1, 1997

Protein kinase associated with gating and closing transmission mechanisms in temporoammonic pathway.

scientific article published in September 2004

Rats harboring S284L Chrna4 mutation show attenuation of synaptic and extrasynaptic GABAergic transmission and exhibit the nocturnal frontal lobe epilepsy phenotype.

scientific article published in November 2008

Relationship between the prefrontal function during a cognitive task and the severity of the symptoms in patients with panic disorder: a multi-channel NIRS study.

scientific article

Relationships between Expenditure of Regional Governments and Suicide Mortalities Caused by Six Major Motives in Japan

scientific article published on 22 December 2021

Sociomedical aspects of epileptic patients: their employment and marital status.

scientific article published in April 2001

Source localization of posterior slow waves of youth using dipole modeling ⬇️

scientific article published on December 1, 2012

Specific panic attack symptoms in panic disorder patients with putative genetic factor

scientific article published on 01 April 2009

Spontaneous epileptic seizures in transgenic rats harboring a human ADNFLE missense mutation in the β2-subunit of the nicotinic acetylcholine receptor

scientific article published on 16 June 2015

Staphylococcal enterotoxin induces emesis through increasing serotonin release in intestine and it is downregulated by cannabinoid receptor 1.

scientific article

The Association of BDNF Val66Met Polymorphism With Trait Anxiety in Panic Disorder.

scientific article published in January 2014

The development of agoraphobia is associated with the symptoms and location of a patient's first panic attack

scientific article

The genetics of febrile seizures and related epilepsy syndromes.

scientific article

Topiramate and zonisamide prevent paradoxical intoxication induced by carbamazepine and phenytoin.

scientific article published on 5 March 2009

Upregulated Connexin 43 Induced by Loss-of-Functional S284L-Mutant α4 Subunit of Nicotinic ACh Receptor Contributes to Pathomechanisms of Autosomal Dominant Sleep-Related Hypermotor Epilepsy

scientific article published on 29 March 2020

Upregulated and Hyperactivated Thalamic Connexin 43 Plays Important Roles in Pathomechanisms of Cognitive Impairment and Seizure of Autosomal Dominant Sleep-Related Hypermotor Epilepsy with S284L-Mutant α4 Subunit of Nicotinic ACh Receptor

scientific article published on 18 May 2020

Upregulation of Intervertebral Disc-Cell Matrix Synthesis by Pulsed Electromagnetic Field Is Mediated by Bone Morphogenetic Proteins ⬇️

scientific article published on May 1, 2013

Vortioxetine Subchronically Activates Serotonergic Transmission via Desensitization of Serotonin 5-HT1A Receptor with 5-HT3 Receptor Inhibition in Rats ⬇️

scientific article published on 10 December 2019

Zonisamide at clinically relevant concentrations inhibits field EPSP but not presynaptic fiber volley in rat frontal cortex.

scientific article published on 26 September 2005

Zonisamide enhances delta receptor-associated neurotransmitter release in striato-pallidal pathway.

scientific article published on 29 May 2009

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