List of works - Rab K Prinjha

A Chemical Probe for the ATAD2 Bromodomain

scientific article

A Chemical Probe for the ATAD2 Bromodomain

article

BET Inhibition Improves NASH and Liver Fibrosis

scientific article published in Scientific Reports

Click chemistry enables preclinical evaluation of targeted epigenetic therapies.

scientific article published on 15 June 2017

Discovery of I-BRD9, a Selective Cell Active Chemical Probe for Bromodomain Containing Protein 9 Inhibition

scientific article

Discovery of a first-in-class reversible DNMT1-selective inhibitor with improved tolerability and efficacy in acute myeloid leukemia

scientific article published on 27 September 2021

Drawing on disorder: How viruses use histone mimicry to their advantage

scientific article published on 22 June 2018

Functional interdependence of BRD4 and DOT1L in MLL leukemia

scientific article published on 13 June 2016

Generation of a Selective Small Molecule Inhibitor of the CBP/p300 Bromodomain for Leukemia Therapy

scientific article

Histone H3K27me3 demethylases regulate human Th17 cell development and effector functions by impacting on metabolism

scientific article published on 02 March 2020

Influenza virus infection causes global RNAPII termination defects

Muscle hypertrophy in hypoxia with inflammation is controlled by bromodomain and extra-terminal domain proteins.

scientific article published on 21 September 2017

SRPK1 maintains acute myeloid leukemia through effects on isoform usage of epigenetic regulators including BRD4

scientific article published in Nature Communications

Selective targeting of BD1 and BD2 of the BET proteins in cancer and immuno-inflammation

scientific article

Signaling function of PRC2 is essential for TCR-driven T cell responses

scientific article published on 09 March 2018

Suppression of the antiviral response by an influenza histone mimic

scientific article

Targeting enhancer switching overcomes non-genetic drug resistance in acute myeloid leukaemia.

scientific article published on 20 June 2019

List of works by Rab K Prinjha

A Chemical Probe for the ATAD2 Bromodomain

A Chemical Probe for the ATAD2 Bromodomain

BET Inhibition Improves NASH and Liver Fibrosis

Click chemistry enables preclinical evaluation of targeted epigenetic therapies.

Discovery of I-BRD9, a Selective Cell Active Chemical Probe for Bromodomain Containing Protein 9 Inhibition

Discovery of a first-in-class reversible DNMT1-selective inhibitor with improved tolerability and efficacy in acute myeloid leukemia

Drawing on disorder: How viruses use histone mimicry to their advantage

Functional interdependence of BRD4 and DOT1L in MLL leukemia

Generation of a Selective Small Molecule Inhibitor of the CBP/p300 Bromodomain for Leukemia Therapy

Histone H3K27me3 demethylases regulate human Th17 cell development and effector functions by impacting on metabolism

Influenza virus infection causes global RNAPII termination defects

Muscle hypertrophy in hypoxia with inflammation is controlled by bromodomain and extra-terminal domain proteins.

SRPK1 maintains acute myeloid leukemia through effects on isoform usage of epigenetic regulators including BRD4

Selective targeting of BD1 and BD2 of the BET proteins in cancer and immuno-inflammation

Signaling function of PRC2 is essential for TCR-driven T cell responses

Suppression of the antiviral response by an influenza histone mimic

Targeting enhancer switching overcomes non-genetic drug resistance in acute myeloid leukaemia.