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List of works by Kasper Almholt

Absence of functional compensation between coagulation factor VIII and plasminogen in double-knockout mice

scientific article published on 01 November 2018

Antibody-Mediated Neutralization of uPA Proteolytic Function Reduces Disease Progression in Mouse Arthritis Models

scientific article published on 27 December 2017

Antibody-mediated Targeting of the Urokinase-type Plasminogen Activator Proteolytic Function Neutralizes Fibrinolysisin Vivo

scientific article published on 17 September 2008

Cancer invasion and tissue remodeling: common themes in proteolytic matrix degradation

scientific article published on 01 October 1998

Concomitant lack of MMP9 and uPA disturbs physiological tissue remodeling ⬇️

scientific article published on July 22, 2011

Extracellular protease mRNAs are predominantly expressed in the stromal areas of microdissected mouse breast carcinomas.

scientific article published on 10 March 2005

Extracellular proteolysis in transgenic mouse models of breast cancer

scientific article published on March 2007

Glucagon-like Peptide-1 receptor agonists activate rodent thyroid C-cells causing calcitonin release and C-cell proliferation.

scientific article

Identification and preclinical development of an anti-proteolytic uPA antibody for rheumatoid arthritis

scientific article published on 27 February 2020

Indication of a role of plasminogen activator inhibitor type I in protecting murine fibrosarcoma cells against apoptosis

scientific article published on 01 October 2005

Lung metastasis fails in MMTV-PyMT oncomice lacking S100A4 due to a T-cell deficiency in primary tumors

scientific article published on 26 January 2010

Metastasis of transgenic breast cancer in plasminogen activator inhibitor-1 gene-deficient mice

scientific article published on 01 July 2003

Plasminogen activation independent of uPA and tPA maintains wound healing in gene-deficient mice.

scientific article

Preclinical pharmacokinetics and biodistribution of subcutaneously administered glycoPEGylated recombinant factor VIII (N8-GP) and development of a human pharmacokinetic prediction model.

scientific article published on 26 March 2018

Profibrinolytic effects of metalloproteinases during skin wound healing in the absence of plasminogen.

scientific article published on 13 March 2008

Sensitive and specific in situ hybridization for early drug discovery.

scientific article published in January 2014

Simultaneous visualization of the translocation of protein kinase Calpha-green fluorescent protein hybrids and intracellular calcium concentrations.

scientific article published on January 1999

Spontaneous metastasis in matrix metalloproteinase 3-deficient mice.

scientific article

Stromal cell involvement in cancer.

scientific article

Target-mediated clearance and bio-distribution of a monoclonal antibody against the Kunitz-type protease inhibitor 2 domain of Tissue Factor Pathway Inhibitor

scientific article published on 17 December 2013

Tumor cell-derived and macrophage-derived cathepsin B promotes progression and lung metastasis of mammary cancer.

scientific article published in May 2006

Urokinase Plasminogen Activator Is a Central Regulator of Macrophage Three-Dimensional Invasion, Matrix Degradation, and Adhesion

scientific article published on 10 March 2014

Urokinase plasminogen activator and receptor promote collagen-induced arthritis through expression in hematopoietic cells

scientific article published on 21 March 2017

Urokinase receptor cleavage correlates with tumor volume in a transgenic mouse model of breast cancer.

scientific article published on 25 March 2015

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