List of works - Quentin J Sattentau

A Plea for Justice for Jailed Medical Workers

scientific article published in Science

A functional human IgM response to HIV-1 Env after immunization with NYVAC HIV C

scientific article published on 01 February 2007

A novel strategy for inducing enhanced mucosal HIV-1 antibody responses in an anti-inflammatory environment

scientific article

A potential molecular mechanism for hypersensitivity caused by formalin-inactivated vaccines

article

A sweet cleft in HIV's armour ⬇️

scientific article published on December 14, 2011

Adhesion molecule interactions facilitate human immunodeficiency virus type 1-induced virological synapse formation between T cells

scientific article published on 3 October 2007

Analysis of memory B cell responses and isolation of novel monoclonal antibodies with neutralizing breadth from HIV-1-infected individuals

scientific article

Anti-HIV IgA isotypes: differential virion capture and inhibition of transcytosis are linked to prevention of mucosal R5 SHIV transmission

scientific article

Antibody-based HIV-1 vaccines: recent developments and future directions

scientific article published on December 2007

Antigenicity and Immunogenicity in HIV-1 Antibody-Based Vaccine Design

scientific article

Architecture and Regulation of the HIV-1 Assembly and Holding Compartment in Macrophages ⬇️

scientific article published on May 25, 2011

Astrocytes Resist HIV-1 Fusion but Engulf Infected Macrophage Material

scientific article published on February 2017

Attachment factors

scientific article published on January 2013

Avoiding the void: cell-to-cell spread of human viruses

scientific article

Candidate polyanionic microbicides inhibit human T-cell lymphotropic virus type 1 receptor interactions, cell-free infection, and cell-cell spread

scientific article

Carnauba wax nanoparticles enhance strong systemic and mucosal cellular and humoral immune responses to HIV-gp140 antigen.

scientific article

Cell-to-Cell Spread of Retroviruses ⬇️

scientific article published on June 10, 2010

Cell-to-cell HIV-1 spread and its implications for immune evasion

scientific article published on March 2009

Cell-to-cell spread of HIV-1 and evasion of neutralizing antibodies

scientific article published on 17 October 2013

Chemical Cross-Linking Stabilizes Native-Like HIV-1 Envelope Glycoprotein Trimer Antigens

scientific article

Comparative efficiency of HIV-1-infected T cell killing by NK cells, monocytes and neutrophils

scientific article

Comparison of neutralizing antibody responses elicited from highly diverse polyvalent heterotrimeric HIV-1 gp140 cocktail immunogens versus a monovalent counterpart in rhesus macaques

scientific article

Correction: HIV-1 envelope glycan modifications that permit neutralization by germline-reverted VRC01-class broadly neutralizing antibodies

article

Correction: Neutralization-guided design of HIV-1 envelope trimers with high affinity for the unmutated common ancestor of CH235 lineage CD4bs broadly neutralizing antibodies

scientific article published on 02 December 2019

Correlates of antibody-mediated protection against HIV infection

scientific article published on May 2008

Cryo-electron tomographic structure of an immunodeficiency virus envelope complex in situ

scientific article published in August 2006

Dangerous liaisons at the virological synapse

scientific article published in September 2004

Defense-in-depth by mucosally administered anti-HIV dimeric IgA2 and systemic IgG1 mAbs: complete protection of rhesus monkeys from mucosal SHIV challenge

scientific article published on 11 March 2015

Development of prophylactic vaccines against HIV-1.

scientific article published on 17 July 2013

Dry roasting enhances peanut-induced allergic sensitization across mucosal and cutaneous routes in mice

scientific article (publication date: December 2014)

EV01: a phase I trial in healthy HIV negative volunteers to evaluate a clade C HIV vaccine, NYVAC-C undertaken by the EuroVacc Consortium.

scientific article

Efferocytosis of Pathogen-Infected Cells

scientific article published on 22 December 2017

Efficient HIV-1 transmission from macrophages to T cells across transient virological synapses

scientific article

Efficient macrophage infection by phagocytosis of dying HIV-1 -infected CD4+T cells.

scientific article published on 3 October 2011

Elimination of retroviral infectivity by N-ethylmaleimide with preservation of functional envelope glycoproteins

scientific article

Envelope Glycoprotein Trimers as HIV-1 Vaccine Immunogens

scientific article published on 28 October 2013

European Union and EDCTP strategy in the global context: Recommendations for preventive HIV/AIDS vaccines research

article

Expression-system-dependent modulation of HIV-1 envelope glycoprotein antigenicity and immunogenicity

scientific article

Fundamental immunology and what it can teach us about HIV vaccine development

scientific article

HIV's gut feeling

scientific article published on 01 March 2008

HIV-1 Envelope Glycan Modifications that Permit Neutralization by Germline-Reverted VRC01-Class Broadly Neutralizing Antibodies

article

HIV-1 cell to cell transfer across an Env-induced, actin-dependent synapse

scientific article

HIV-1-neutralizing antibody induced by simian adenovirus- and poxvirus MVA-vectored BG505 native-like envelope trimers

scientific article published on 9 August 2017

Heparan sulfate targets the HIV-1 envelope glycoprotein gp120 coreceptor binding site.

scientific article

High multiplicity HIV-1 cell-to-cell transmission from macrophages to CD4+ T cells limits antiretroviral efficacy

scientific article

High-multiplicity HIV-1 infection and neutralizing antibody evasion mediated by the macrophage-T cell virological synapse.

scientific article

Human T-cell leukemia virus type 1 envelope glycoprotein gp46 interacts with cell surface heparan sulfate proteoglycans

scientific article

Human immunodeficiency virus type 1 assembly, budding, and cell-cell spread in T cells take place in tetraspanin-enriched plasma membrane domains

scientific article published on 23 May 2007

Human immunodeficiency virus type 1 virological synapse formation in T cells requires lipid raft integrity

scientific article published on September 2005

Human monoclonal antibodies to HIV-1 gp140 from mice bearing YAC-based human immunoglobulin transloci ⬇️

scientific article published on August 2, 2011

Immunogen design to focus the B-cell repertoire

scientific article published on May 2014

Immunological and pathological outcomes of SARS-CoV-2 challenge following formalin-inactivated vaccine in ferrets and rhesus macaques

scientific article published on 10 September 2021

Improved HIV-1 specific T-cell responses by short-interval DNA tattooing as compared to intramuscular immunization in non-human primates

article

Interfacial metal and antibody recognition

scientific article

International network for comparison of HIV neutralization assays: the NeutNet report

scientific article

International network for comparison of HIV neutralization assays: the NeutNet report II

scientific article (publication date: 2012)

Macrophage infection via selective capture of HIV-1-infected CD4+ T cells

scientific article

Macrophages and HIV-1: An Unhealthy Constellation

scientific article

Membrane nanotubes physically connect T cells over long distances presenting a novel route for HIV-1 transmission

scientific article

Mixed adjuvant formulations reveal a new combination that elicit antibody response comparable to Freund's adjuvants

scientific article (publication date: 2012)

Multiple proviral integration events after virological synapse-mediated HIV-1 spread

scientific article published on 28 May 2013

Nasal Immunization Confers High Avidity Neutralizing Antibody Response and Immunity to Primary and Recurrent Genital Herpes in Guinea Pigs

scientific article published on 26 December 2016

Neutralization of Infectivity of Diverse R5 Clinical Isolates of Human Immunodeficiency Virus Type 1 by gp120-Binding 2′F-RNA Aptamers ⬇️

scientific article published on December 1, 2003

Neutralization-guided design of HIV-1 envelope trimers with high affinity for the unmutated common ancestor of CH235 lineage CD4bs broadly neutralizing antibodies

scientific article published on 17 September 2019

New templates for HIV-1 antibody-based vaccine design

scientific article

Polyethyleneimine is a potent mucosal adjuvant for viral glycoprotein antigens

scientific article

Polyethyleneimine is a potent systemic adjuvant for glycoprotein antigens

scientific article published on 20 May 2014

Potent adaptive immune responses induced against HIV-1 gp140 and influenza virus HA by a polyanionic carbomer

scientific article

Production and characterization of high-affinity human monoclonal antibodies to human immunodeficiency virus type 1 envelope glycoproteins in a mouse model expressing human immunoglobulins.

scientific article

RNA Helicase DDX1 Converts RNA G-Quadruplex Structures into R-Loops to Promote IgH Class Switch Recombination.

scientific article published on 3 May 2018

Re: “Enhancement of HIV Infection by Cellulose Sulfate,” by Tao et al

article

Reactive carbonyls are a major Th2-inducing damage-associated molecular pattern generated by oxidative stress.

scientific article

Refocussing Antibody Responses by Chemical Modification of Vaccine Antigens

article

Regulated secretion from CD4+ T cells.

scientific article published on 24 October 2007

Requirement for an intact T-cell actin and tubulin cytoskeleton for efficient assembly and spread of human immunodeficiency virus type 1.

scientific article published on 14 March 2007

Retroviral spread by induction of virological synapses

scientific article published in September 2004

Retroviruses and the Third Synapse ⬇️

scientific article published on April 15, 2010

SDF-1/CXCL12 production by mature dendritic cells inhibits the propagation of X4-tropic HIV-1 isolates at the dendritic cell-T-cell infectious synapse.

scientific article published on 24 February 2010

Stabilized HIV-1 envelope glycoprotein trimers for vaccine use.

scientific article

Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors

scientific article

Structural and immunologic correlates of chemically stabilized HIV-1 envelope glycoproteins.

scientific article

Synergistic inhibition of HIV-1 infection by combinations of soluble polyanions with other potential microbicides

scientific article published on 26 March 2007

The Carbomer-Lecithin Adjuvant Adjuplex Has Potent Immunoactivating Properties and Elicits Protective Adaptive Immunity against Influenza Virus Challenge in Mice.

scientific article

The HIV-1-containing macrophage compartment: a perfect cellular niche?

scientific article published on 02 June 2013

The autophagy gene Atg16l1 differentially regulates Treg and TH2 cells to control intestinal inflammation.

scientific article published on 24 February 2016

The direct passage of animal viruses between cells ⬇️

scientific article published on 06 October 2011

The prospects for vaccines against HIV-1: more than a field of long-term nonprogression?

scientific article

The regulated secretory pathway in CD4(+) T cells contributes to human immunodeficiency virus type-1 cell-to-cell spread at the virological synapse

scientific article (publication date: September 2011)

The regulated secretory pathway in CD4+T cells contributes to HIV-1 transmission at the virological synapse.

scientific article published on 3 October 2011

Thymic stromal lymphopoietin-elicited basophil responses promote eosinophilic esophagitis.

scientific article published on 21 July 2013

V3: HIV's switch-hitter

scientific article

Viral determinants of HIV-1 macrophage tropism

scientific article published on 15 November 2011

Virological synapse-mediated spread of human immunodeficiency virus type 1 between T cells is sensitive to entry inhibition

scientific article

List of works by Quentin J Sattentau

A Plea for Justice for Jailed Medical Workers

A functional human IgM response to HIV-1 Env after immunization with NYVAC HIV C

A novel strategy for inducing enhanced mucosal HIV-1 antibody responses in an anti-inflammatory environment

A potential molecular mechanism for hypersensitivity caused by formalin-inactivated vaccines

A sweet cleft in HIV's armour ⬇️

Adhesion molecule interactions facilitate human immunodeficiency virus type 1-induced virological synapse formation between T cells

Analysis of memory B cell responses and isolation of novel monoclonal antibodies with neutralizing breadth from HIV-1-infected individuals

Anti-HIV IgA isotypes: differential virion capture and inhibition of transcytosis are linked to prevention of mucosal R5 SHIV transmission

Antibody-based HIV-1 vaccines: recent developments and future directions

Antigenicity and Immunogenicity in HIV-1 Antibody-Based Vaccine Design

Architecture and Regulation of the HIV-1 Assembly and Holding Compartment in Macrophages ⬇️

Astrocytes Resist HIV-1 Fusion but Engulf Infected Macrophage Material

Attachment factors

Avoiding the void: cell-to-cell spread of human viruses

Candidate polyanionic microbicides inhibit human T-cell lymphotropic virus type 1 receptor interactions, cell-free infection, and cell-cell spread

Carnauba wax nanoparticles enhance strong systemic and mucosal cellular and humoral immune responses to HIV-gp140 antigen.

Cell-to-Cell Spread of Retroviruses ⬇️

Cell-to-cell HIV-1 spread and its implications for immune evasion

Cell-to-cell spread of HIV-1 and evasion of neutralizing antibodies

Chemical Cross-Linking Stabilizes Native-Like HIV-1 Envelope Glycoprotein Trimer Antigens

Comparative efficiency of HIV-1-infected T cell killing by NK cells, monocytes and neutrophils

Comparison of neutralizing antibody responses elicited from highly diverse polyvalent heterotrimeric HIV-1 gp140 cocktail immunogens versus a monovalent counterpart in rhesus macaques

Correction: HIV-1 envelope glycan modifications that permit neutralization by germline-reverted VRC01-class broadly neutralizing antibodies

Correction: Neutralization-guided design of HIV-1 envelope trimers with high affinity for the unmutated common ancestor of CH235 lineage CD4bs broadly neutralizing antibodies

Correlates of antibody-mediated protection against HIV infection

Cryo-electron tomographic structure of an immunodeficiency virus envelope complex in situ

Dangerous liaisons at the virological synapse

Defense-in-depth by mucosally administered anti-HIV dimeric IgA2 and systemic IgG1 mAbs: complete protection of rhesus monkeys from mucosal SHIV challenge

Development of prophylactic vaccines against HIV-1.

Dry roasting enhances peanut-induced allergic sensitization across mucosal and cutaneous routes in mice

EV01: a phase I trial in healthy HIV negative volunteers to evaluate a clade C HIV vaccine, NYVAC-C undertaken by the EuroVacc Consortium.

Efferocytosis of Pathogen-Infected Cells

Efficient HIV-1 transmission from macrophages to T cells across transient virological synapses

Efficient macrophage infection by phagocytosis of dying HIV-1 -infected CD4+T cells.

Elimination of retroviral infectivity by N-ethylmaleimide with preservation of functional envelope glycoproteins

Envelope Glycoprotein Trimers as HIV-1 Vaccine Immunogens

European Union and EDCTP strategy in the global context: Recommendations for preventive HIV/AIDS vaccines research

Expression-system-dependent modulation of HIV-1 envelope glycoprotein antigenicity and immunogenicity

Fundamental immunology and what it can teach us about HIV vaccine development

HIV's gut feeling

HIV-1 Envelope Glycan Modifications that Permit Neutralization by Germline-Reverted VRC01-Class Broadly Neutralizing Antibodies

HIV-1 cell to cell transfer across an Env-induced, actin-dependent synapse

HIV-1-neutralizing antibody induced by simian adenovirus- and poxvirus MVA-vectored BG505 native-like envelope trimers

Heparan sulfate targets the HIV-1 envelope glycoprotein gp120 coreceptor binding site.

High multiplicity HIV-1 cell-to-cell transmission from macrophages to CD4+ T cells limits antiretroviral efficacy

High-multiplicity HIV-1 infection and neutralizing antibody evasion mediated by the macrophage-T cell virological synapse.

Human T-cell leukemia virus type 1 envelope glycoprotein gp46 interacts with cell surface heparan sulfate proteoglycans

Human immunodeficiency virus type 1 assembly, budding, and cell-cell spread in T cells take place in tetraspanin-enriched plasma membrane domains

Human immunodeficiency virus type 1 virological synapse formation in T cells requires lipid raft integrity

Human monoclonal antibodies to HIV-1 gp140 from mice bearing YAC-based human immunoglobulin transloci ⬇️

Immunogen design to focus the B-cell repertoire

Immunological and pathological outcomes of SARS-CoV-2 challenge following formalin-inactivated vaccine in ferrets and rhesus macaques

Improved HIV-1 specific T-cell responses by short-interval DNA tattooing as compared to intramuscular immunization in non-human primates

Interfacial metal and antibody recognition

International network for comparison of HIV neutralization assays: the NeutNet report

International network for comparison of HIV neutralization assays: the NeutNet report II

Macrophage infection via selective capture of HIV-1-infected CD4+ T cells

Macrophages and HIV-1: An Unhealthy Constellation

Membrane nanotubes physically connect T cells over long distances presenting a novel route for HIV-1 transmission

Mixed adjuvant formulations reveal a new combination that elicit antibody response comparable to Freund's adjuvants

Multiple proviral integration events after virological synapse-mediated HIV-1 spread

Nasal Immunization Confers High Avidity Neutralizing Antibody Response and Immunity to Primary and Recurrent Genital Herpes in Guinea Pigs

Neutralization of Infectivity of Diverse R5 Clinical Isolates of Human Immunodeficiency Virus Type 1 by gp120-Binding 2′F-RNA Aptamers ⬇️

Neutralization-guided design of HIV-1 envelope trimers with high affinity for the unmutated common ancestor of CH235 lineage CD4bs broadly neutralizing antibodies

New templates for HIV-1 antibody-based vaccine design

Polyethyleneimine is a potent mucosal adjuvant for viral glycoprotein antigens

Polyethyleneimine is a potent systemic adjuvant for glycoprotein antigens

Potent adaptive immune responses induced against HIV-1 gp140 and influenza virus HA by a polyanionic carbomer

Production and characterization of high-affinity human monoclonal antibodies to human immunodeficiency virus type 1 envelope glycoproteins in a mouse model expressing human immunoglobulins.

RNA Helicase DDX1 Converts RNA G-Quadruplex Structures into R-Loops to Promote IgH Class Switch Recombination.

Re: “Enhancement of HIV Infection by Cellulose Sulfate,” by Tao et al

Reactive carbonyls are a major Th2-inducing damage-associated molecular pattern generated by oxidative stress.

Refocussing Antibody Responses by Chemical Modification of Vaccine Antigens

Regulated secretion from CD4+ T cells.

Requirement for an intact T-cell actin and tubulin cytoskeleton for efficient assembly and spread of human immunodeficiency virus type 1.

Retroviral spread by induction of virological synapses

Retroviruses and the Third Synapse ⬇️

SDF-1/CXCL12 production by mature dendritic cells inhibits the propagation of X4-tropic HIV-1 isolates at the dendritic cell-T-cell infectious synapse.

Stabilized HIV-1 envelope glycoprotein trimers for vaccine use.