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List of works by Andrea Biondi

A Childhood Leukaemia Cluster in Milan: Possible Role of Pandemic AH1N1 Swine Flu Virus. ⬇️

scholarly article

A European paediatric cancer mission: aspiration or reality?

scientific article published on 01 September 2019

A Multicenter Phase II Study of Sequential Administration of Unmanipulated DLI and Donor Derived Cytokine Induced Killer (CIK) Cells in HSCT Patients, Relapsed of Disease ⬇️

scholarly article

A Question of Frame: The Role of the Bone Marrow Stromal Niche in Myeloid Malignancies

scientific article published in 2023

A Simple RNA Target Capture NGS Strategy for Fusion Genes Assessment in the Diagnostics of Pediatric B-cell Acute Lymphoblastic Leukemia

scientific article published on 04 June 2019

A Versatile DNA/RNA NGS Targeted Capture Strategy for Detection of Fusion Genes in Pediatric ALL ⬇️

scholarly article

A boy with Burkitt lymphoma associated with Noonan syndrome due to a mutation in RAF1.

scientific article published on 23 April 2013

A case of Philadelphia Positive Acute Lymphoblastic Leukaemia with three different phenotypic lineage, each one presenting the same BCR-ABL hybrid transcript

scientific article published on 23 May 2009

A human immunodeficiency virus type 1 pol gene-derived sequence (cPPT/CTS) increases the efficiency of transduction of human nondividing monocytes and T lymphocytes by lentiviral vectors

scientific article published in October 2002

A new case report of severe mucopolysaccharidosis type VII: diagnosis, treatment with haematopoietic cell transplantation and prenatal diagnosis in a second pregnancy

scientific article published on 16 November 2018

A single high dose of idarubicin combined with high-dose ARA-C for treatment of first relapse in childhood 'high-risk' acute lymphoblastic leukaemia: a study of the AIEOP group

scientific article published in September 2002

A treatment protocol for infants younger than 1 year with acute lymphoblastic leukaemia (Interfant-99): an observational study and a multicentre randomised trial

scientific article published in July 2007

A wide role for NOTCH1 signaling in acute leukemia

scientific article

AIEOP-BFM consensus guidelines 2016 for flow cytometric immunophenotyping of Pediatric acute lymphoblastic leukemia.

scientific article published on 10 February 2017

Abnormally expanded pro-B hematogones associated with congenital cytomegalovirus infection

scientific article published on 01 October 2007

Absent B cells, agammaglobulinemia, and hypertrophic cardiomyopathy in Folliculin Interacting Protein 1 deficiency

scientific article published on 09 September 2020

Activin A contributes to the definition of a pro-oncogenic bone marrow microenvironment in t(12;21) preleukemia

scientific article published on 28 February 2019

ActivinA: a new leukemia-promoting factor conferring migratory advantage to B-cell precursor-acute lymphoblastic leukemic cells

scientific article published on 27 September 2018

Acute Myeloid Leukemia Targeting by Chimeric Antigen Receptor T Cells: Bridging the Gap from Preclinical Modeling to Human Studies

scientific article published on 14 December 2016

Acute lymphoblastic leukemia in children with Down syndrome: a retrospective analysis from the Ponte di Legno study group

scientific article

Acute myeloid leukaemia niche regulates response to L-asparaginase

scientific article published on 01 May 2019

Acute myeloid leukemia shapes the bone marrow stromal niche in vivo

scientific article published on 07 May 2020

Additional cytogenetic abnormalities and variant t(9;22) at the diagnosis of childhood chronic myeloid leukemia: The experience of the International Registry for Chronic Myeloid Leukemia in Children and Adolescents.

scientific article

Adolescents with Cancer in Italy: Improving Access to National Cooperative Pediatric Oncology Group (AIEOP) Centers

scientific article

Adolescents’ Health Awareness and Understanding of Cancer and Tumor Prevention: When and Why an Adolescent Decides to Consult a Physician

article

Advanced targeted, cell and gene-therapy approaches for pediatric hematological malignancies: results and future perspectives

scientific article published on 30 April 2013

Agranulocytosis due to deferiprone: a case report with cytomorphological and functional bone marrow examination ⬇️

scientific article published on July 18, 2011

Allogeneic mesenchymal stem cell infusion for the stabilization of focal segmental glomerulosclerosis.

scientific article

An Extensive Quality Control and Quality Assurance (QC/QA) Program Significantly Improves Inter-Laboratory Concordance Rates of Flow-Cytometric Minimal Residual Disease Assessment in Acute Lymphoblastic Leukemia: An I-BFM-FLOW-Network Report

scientific article published on 6 December 2021

An Inv(16)(p13.3q24.3)-encoded CBFA2T3-GLIS2 fusion protein defines an aggressive subtype of pediatric acute megakaryoblastic leukemia

scientific article published on November 2012

An immune-based biomarker signature is associated with mortality in COVID-19 patients

scientific article published on 24 November 2020

Analysis of a Global Registration Trial of the Efficacy and Safety of CTL019 in Pediatric and Young Adults with Relapsed/Refractory Acute Lymphoblastic Leukemia (ALL) ⬇️

scholarly article

Antileukemic Efficacy of BET Inhibitor in a Preclinical Mouse Model of MLL-AF4 Infant ALL

scientific article published on 10 May 2018

Antitumour activity of trabectedin in myelodysplastic/myeloproliferative neoplasms.

scientific article published on 10 January 2017

Asparagine levels in the cerebrospinal fluid of children with acute lymphoblastic leukemia treated with pegylated-asparaginase in the induction phase of the AIEOP-BFM ALL 2009 study

scientific article published on 31 January 2019

Assessment of submicroscopic genetic lesions by single nucleotide polymorphism arrays in a child with acute myeloid leukemia and FLT3-internal tandem duplication

scientific article published on 01 June 2006

Ataluren-driven Restoration of Shwachman-Bodian-Diamond Syndrome Protein Function in Shwachman-Diamond Syndrome Bone Marrow Cells

scientific article

Auto-antibodies against type I IFNs in patients with life-threatening COVID-19

scientific article published on 24 September 2020

Autoantibodies neutralizing type I IFNs are present in 4% of uninfected individuals over 70 years old and account for 20% of COVID-19 deaths

scientific article published on 19 August 2021

Autologous purified peripheral blood stem cell transplantation compare to chemotherapy in childhood acute lymphoblastic leukemia after low‐risk relapse ⬇️

scientific article published on May 16, 2011

BCR-ABL1-like acute lymphoblastic leukemia in childhood and targeted therapy

scientific article published on 15 May 2020

Balance of Anti-CD123 Chimeric Antigen Receptor (CAR) Binding Affinity and Density for the Treatment of Acute Myeloid Leukemia ⬇️

scholarly article

Balance of Anti-CD123 Chimeric Antigen Receptor Binding Affinity and Density for the Targeting of Acute Myeloid Leukemia

scientific article published on 3 May 2017

Biological Features and Prognostic Impact of CRLF2 Overexpression In Childhood ALL ⬇️

scholarly article

Bone Marrow Mesenchymal Stromal Cells and Inflammation Contribute to ETV6-RUNX1+ Preleukemic Cells Persistence and DNA Damaging ⬇️

scholarly article

Both carboxy-terminus NES motif and mutated tryptophan(s) are crucial for aberrant nuclear export of nucleophosmin leukemic mutants in NPMc+ AML.

scientific article published on 2 February 2006

C-kit+ cardiac progenitors exhibit mesenchymal markers and preferential cardiovascular commitment.

scientific article published on 10 September 2010

CD123 AML targeting by chimeric antigen receptors: A novel magic bullet for AML therapeutics?

scientific article published on 14 May 2014

CD34+ stem cell recovery after positive selection of "overloaded" immunomagnetic columns

scientific article published in December 2005

CD40 activation of BCP-ALL cells generates IL-10-producing, IL-12-defective APCs that induce allogeneic T-cell anergy

scientific article published on 4 March 2004

CI-FISH, GEP, and SNPs Correlate Genomic Categories with Risk Stratification in Children with T-ALL. ⬇️

scholarly article

CRLF2 over-expression is a poor prognostic marker in children with high risk T-cell acute lymphoblastic leukemia

scientific article published on 15 July 2016

Characterization of CD34+, CD13+, CD33- cells, a rare subset of immature human hematopoietic cells

scientific article published on 01 April 2002

Characterization of in vitro migratory properties of anti-CD19 chimeric receptor-redirected CIK cells for their potential use in B-ALL immunotherapy

scientific article published in September 2006

Characterization of migratory activity and cytokine profile of helper and cytotoxic CMV-specific T-cell lines expanded by a selective peptide library

scientific article

Characterization of the human myeloid leukemia-derived cell line GF-D8 by multiplex fluorescence in situ hybridization, subtelomeric probes, and comparative genomic hybridization

Chemerin Produced By Mesenchymal Stromal Cells (MSC) Is an Important Factor for In Vivo macrophage Migration ⬇️

scholarly article

Chemotherapy induces canalization of cell state in childhood B-cell precursor acute lymphoblastic leukemia

scientific article published on 05 July 2021

Childhood high-risk acute lymphoblastic leukemia in first remission: results after chemotherapy or transplant from the AIEOP ALL 2000 study

scientific article published on 10 January 2014

Children with cancer in the time of COVID-19: An 8-week report from the six pediatric onco-hematology centers in Lombardia, Italy

scientific article published on 26 May 2020

Chimeric T-cell receptors: new challenges for targeted immunotherapy in hematologic malignancies

scientific article published on March 2007

Clinical Implications of Minimal Residual Disease Detection in Infants With <i>KMT2A</i>-Rearranged Acute Lymphoblastic Leukemia Treated on the Interfant-06 Protocol

scientific article published on 06 January 2021

Clinical and Biological Characterization of Children with FLT3ITD Mutated Acute Myeloid Leukemia (AML): A Report from the AIEOP AML-2002 Study Group ⬇️

scholarly article

Clinical and molecular genetic characterization of wild-type MLL infant acute lymphoblastic leukemia identifies few recurrent abnormalities

scientific article published on 17 December 2015

Clinical features and outcome of SIL/TAL1-positive T-cell acute lymphoblastic leukemia in children and adolescents: a 10-year experience of the AIEOP group

scientific article published on 10 October 2014

Clinico-biological features of 5202 patients with acute lymphoblastic leukemia enrolled in the Italian AIEOP and GIMEMA protocols and stratified in age cohorts

scientific article published on 28 May 2013

Clonal Evolution and Lack of BCR-ABL1 Mutations in Pediatric Ph+ ALL Patients Resistant/Refractory to Imatinib Treatment ⬇️

scholarly article

Collaboration between Activating Mutations in JAK2 and Trisomy 21 in the Acute Lymphoblastic Leukemias of Down Syndrome (DS). ⬇️

scholarly article

Collaboration of the Meningioma 1 (MN1) Oncogene with MLL-Fusions in Pediatric Leukemia ⬇️

scholarly article

Collateral effects of COVID-19 pandemic in pediatric hematooncology: Fatalities caused by diagnostic delay

scientific article published on 11 June 2020

Combined cord blood and bone marrow transplantation from the same human leucocyte antigen-identical sibling donor for children with malignant and non-malignant diseases

scientific article published on 18 December 2014

Combined expression of pTalpha and Notch3 in T cell leukemia identifies the requirement of preTCR for leukemogenesis

scientific article

Combining the Expression of CD33.CAR and CXCR4 to Increase CAR-CIK Cell Homing to Bone Marrow Niche and Leukemic Stem Cell Eradication in Acute Myeloid Leukemia

scientific article published on 23 November 2021

Commitment of juvenile myelo-monocytic (JMML) leukemic cells to spontaneously differentiate into dendritic cells

scientific article

Comparative analysis of multilineage properties of mesenchymal stromal cells derived from fetal sources shows an advantage of mesenchymal stromal cells isolated from cord blood in chondrogenic differentiation potential

scientific article published in May 2014

Comparison of Dfferent Suicide Gene Strategies for the Safety Improvement of Genetically Manipulated T Cells. ⬇️

scholarly article

Comparison of MRD Monitoring By IG/TR Rearrangement and BCR/ABL1 Transcript in Ph+ Pediatric Acute Lymphoblastic Leukemia Patients Treated with Imatinib in the Esphall Study ⬇️

scholarly article

Comparison of different suicide-gene strategies for the safety improvement of genetically manipulated T cells.

scientific article published on December 2012

Constitutional Segmental Uniparental Disomy in a Twin Pair with t(12;21) Positive Acute Lymphoblastic Leukemia Characterized by the Same Prenatal Clone and Divergent Clonal Evolution. ⬇️

scholarly article

Cross-linking of the mannose receptor on monocyte-derived dendritic cells activates an anti-inflammatory immunosuppressive program

scientific article published in November 2003

CyclinD1 Down-Regulation and Increased Apoptosis Are Common Features of Cohesinopathies

scientific article published on 23 July 2015

Cytokine-induced killer cells for cell therapy of acute myeloid leukemia: improvement of their immune activity by expression of CD33-specific chimeric receptors

scientific article published on 16 August 2010

Cytoskeletal Regulatory Gene Expression and Migratory Properties of B-cell Progenitors Are Affected by the ETV6-RUNX1 Rearrangement

article

Defining and listing very rare cancers of paediatric age: consensus of the Joint Action on Rare Cancers in cooperation with the European Cooperative Study Group for Pediatric Rare Tumors

scientific article published on 19 February 2019

Defining the correct role of minimal residual disease tests in the management of acute lymphoblastic leukaemia ⬇️

scientific article published on 04 August 2011

Description and Management of Accelerated Phase and Blast Crisis in 21 CML Pediatric Patients ⬇️

scholarly article

Detection of CALM-AF10 Fusion Transcript Does Not Predict A Poor Prognosis in Children with T-Lineage Acute Lymphoblastic Leukemia Treated with AIEOP ALL 2000 Protocol and Subsequent Modified 2000 Study (R-2006). ⬇️

scholarly article

Detection of minimal residual disease identifies differences in treatment response between T-ALL and precursor B-ALL.

scientific article published in June 2002

Detection of minimal residual disease in pediatric acute lymphoblastic leukemia

scientific article published on 26 June 2013

Detection of prognostically relevant genetic abnormalities in childhood B-cell precursor acute lymphoblastic leukaemia: recommendations from the Biology and Diagnosis Committee of the International Berlin-Frankfürt-Münster study group

scientific article published on October 2010

Development of advanced therapies in Italy: Management models and sustainability in six Italian cell factories

scientific article

Development of an algorithm for the management of cervical lymphadenopathy in children: consensus of the Italian Society of Preventive and Social Pediatrics, jointly with the Italian Society of Pediatric Infectious Diseases and the Italian Society o

scientific article

Developmental origins and impact of BCR-ABL1 fusion and IKZF1 deletions in monozygotic twins with Ph+ acute lymphoblastic leukemia

scientific article published on 29 September 2011

Dexamethasone Stimulation Test in the Diagnostic Work-Up of Growth Hormone Deficiency in Childhood: Clinical Value and Comparison With Insulin-Induced Hypoglycemia

scientific article published on 09 December 2020

Dexamethasone vs prednisone in induction treatment of pediatric ALL: results of the randomized trial AIEOP-BFM ALL 2000.

scientific article published on 17 February 2016

Diagnosis and monitoring of PML-RARA-positive acute promyelocytic leukemia by qualitative RT-PCR.

scientific article

Digital-Droplet PCR, an Accurate Method for IG/TR PCR-MRD Stratification in Childhood Acute Lymphoblastic Leukemia ⬇️

scholarly article

Dominant-Negative Impact of PAX5/TEL on Downstream Targets of PAX5 and Essential Pre-B Cell Receptor Genes ⬇️

scholarly article

Donor-derived CD19-targeted T cells in allogeneic transplants

scientific article published on 18 September 2015

Dysregulation of NIPBL leads to impaired RUNX1 expression and haematopoietic defects

scientific article published on 23 April 2020

ETV6–RUNX1 fusion gene and additional genetic changes in infant leukemia: a genome-wide analysis

article

Early Response Does Not Impact on the Long-Term Outcome of Children and Adolescents with Chronic Myeloid Leukemia Treated with High-Dose Imatinib. the Italian Experience ⬇️

scholarly article

Early T-cell precursor acute lymphoblastic leukaemia in children treated in AIEOP centres with AIEOP-BFM protocols: a retrospective analysis

scientific article published on 26 January 2016

Early T-cell precursor leukaemia: a subtype of very high-risk acute lymphoblastic leukaemia

scientific article

Early response does not predict outcome in children and adolescents with chronic myeloid leukaemia treated with high-dose imatinib

scientific article

Effects of plasma transfusion on hepcidin production in human congenital hypotransferrinemia

article

Efficacy and Safety of Imatinib on Top of BFM-Like Chemotherapy in Pediatric Patients with Ph+/BCR-ABL+ Acute Lymphoblastic Leukemia (Ph+ALL). the EsPhALL Study ⬇️

scholarly article

Either IL-7 activation of JAK-STAT or BEZ inhibition of PI3K-AKT-mTOR pathways dominates the single-cell phosphosignature of ex vivo treated pediatric T-cell acute lymphoblastic leukemia cells

scientific article published in 2021

Engineered T cells towards TNFRSF13C (BAFFR): a novel strategy to efficiently target B-cell acute lymphoblastic leukaemia

scientific article published on 18 August 2017

Engineering tandem CD33xCD146 CAR CIK (cytokine-induced killer) cells to target the acute myeloid leukemia niche

scientific article published in 2023

Enhancement of the anti-leukemic activity of cytokine induced killer cells with an anti-CD19 chimeric receptor delivering a 4-1BB-ζ activating signal

scientific article published on 25 July 2007

Enzymatic replacement therapy for Hunter disease: Up to 9 years experience with 17 patients.

scientific article published on 22 April 2015

Epigenetic silencing of BIM in glucocorticoid poor-responsive pediatric acute lymphoblastic leukemia, and its reversal by histone deacetylase inhibition.

scientific article published on 20 July 2010

Establishment of bone marrow and hematopoietic niches in vivo by reversion of chondrocyte differentiation of human bone marrow stromal cells

scientific article

Euroflow-Based Immunophenotypic Characterization of CD34+ Cell Compartment in Juvenile Myelomonocytic Leukemia (JMML): A New Tool for Differential Diagnosis ⬇️

scholarly article

Evaluation of Minimal Residual Disease As a Surrogate Endpoint for Event Free Survival in Childhood B-Lineage Acute Lymphoblastic Leukemia ⬇️

scholarly article

Evaluation of Technical Issues in a Pilot Multicenter Newborn Screening Program for Sickle Cell Disease

scientific article published on 21 December 2018

Evaluation of the Pattern of Use of a Pediatric Emergency Department in Italy

scientific article published on 30 March 2020

Expression of CD58 in normal, regenerating and leukemic bone marrow B cells: implications for the detection of minimal residual disease in acute lymphocytic leukemia ⬇️

scientific article published on 01 November 2003

Extracorporeal photochemotherapy is accompanied by increasing levels of circulating CD4+CD25+GITR+Foxp3+CD62L+ functional regulatory T-cells in patients with graft-versus-host disease

scientific article published on 01 July 2007

Extramedullary involvement in patients with acute promyelocytic leukemia

FLT3 internal tandem duplication in childhood acute myeloid leukaemia: association with hyperleucocytosis in acute promyelocytic leukaemia.

scientific article

Failure of interferon-γ pre-treated mesenchymal stem cell treatment in a patient with Crohn's disease

scientific article

Favorable Outcome of Children with Acute Megakaryoblastic Leukemia Treated with the AIEOP AML 2002/01 Protocol ⬇️

scholarly article

Fine tuning of surface CRLF2 expression and its associated signaling profile in childhood B-cell precursor acute lymphoblastic leukemia.

scientific article published on 10 April 2015

First evidence of a paediatric patient with Cornelia de Lange syndrome with acute lymphoblastic leukaemia

scientific article published on 04 April 2019

From Adjustment to Thriving: Exploring Well-Being in Young Adult Survivors of Childhood Cancer and Their Siblings

scientific article published on 13 June 2016

From bone marrow transplantation to cellular therapies: possible therapeutic strategies in managing autoimmune disorders

scientific article published in January 2012

Full GMP-compliant validation of bone marrow-derived human CD133(+) cells as advanced therapy medicinal product for refractory ischemic cardiomyopathy.

scientific article

GIMEMA-AIEOP AIDA Protocols for the Treatment of Newly Diagnosed Acute Promyelocytic Leukemia (APL) In Children: Analysis of 247 Patients Enrolled In Two Sequential Italian Multicenter Trials ⬇️

scholarly article

GIMEMA-AIEOPAIDA protocol for the treatment of newly diagnosed acute promyelocytic leukemia (APL) in children

scientific article

GMP-based CD133(+) cells isolation maintains progenitor angiogenic properties and enhances standardization in cardiovascular cell therapy

scientific article published on 20 July 2009

Gain-of-function mutations in interleukin-7 receptor-α (IL7R) in childhood acute lymphoblastic leukemias ⬇️

scientific article

Gain-of-function mutations ininterleukin-7 receptor-α (IL7R) in childhood acute lymphoblastic leukemias

Generation of Cytomegalovirus (CMV)-Specific CD4 and CD8 T Cell Lines Using Protein-Spanning Pools of pp65 and IE1 Derived Peptides. ⬇️

scholarly article

Generation of a New Chimeric Antigen Receptor (CAR) to Target CD23 Expressed on Chronic Lymphocytic Leukemia (B-CLL) Cells ⬇️

scholarly article

Generic formulations of imatinib for treatment of Philadelphia chromosome-positive leukemia in pediatric patients

scientific article published on 30 August 2018

Genetic evidence for lineage-related and differentiation stage-related contribution of somatic PTPN11 mutations to leukemogenesis in childhood acute leukemia

scientific article published on 24 February 2004

Genetic predisposition to hemophagocytic lymphohistiocytosis: Report on 500 patients from the Italian registry

scientific article

Genetics Directing Therapy in Acute Lymphocytic Leukemia: Identifying Risk, Defining Targets ⬇️

scholarly article

Genomewide Association Study of Severe Covid-19 with Respiratory Failure

scientific article published on 17 June 2020

Genomic and Transcriptomic Analyses Revealed Differences and Similarities Between T-Lbl and T-ALL . ⬇️

scholarly article

Genotypes of the glutathione S-transferase superfamily do not correlate with outcome of childhood acute lymphoblastic leukemia ⬇️

scientific article published on May 1, 2003

Germ-Line TP53 Mutation in an Adolescent With CMML/Atypical CML and Familiar Cancer Predisposition

scientific article published on 17 September 2020

Glutathione S-transferase homozygous deletions and relapse in childhood acute lymphoblastic leukemia: a novel study design in a large Italian AIEOP cohort

scientific article published in December 2012

Hepatic Granulomatous Lesions Caused by Systemic Bartonella vinsonii subsp. arupensis Infection in a Child

scientific article

Heterogeneity of the bone marrow niche in patients with myeloproliferative neoplasms: ActivinA secretion by mesenchymal stromal cells correlates with the degree of marrow fibrosis

scientific article published on 21 October 2020

Heterozygous Mutation in Adenosine Deaminase Gene in a Patient With Severe Lymphopenia Following Corticosteroid Treatment of Autoimmune Hemolytic Anemia

article

High Clonal Evolution Rate in Relapsing Infant ALL Patients. ⬇️

scholarly article

High Dose Imatinib Is Effective In Children and Adolescents With Chronic Myelogenous Leukemia In Chronic Phase. The Italian Experience ⬇️

scholarly article

High EVI1 Expression due to NRIP1/EVI1 Fusion in Therapy-related Acute Myeloid Leukemia: Description of the First Pediatric Case

scientific article published on 17 September 2020

High expression of miR-125b-2 and SNORD116 noncoding RNA clusters characterize ERG-related B cell precursor acute lymphoblastic leukemia.

scientific article published on 21 March 2017

Hodgkin lymphoma in a patient with mosaic trisomy 18: First clinical observation

scientific article published on 24 December 2015

How I treat infant leukemia

scientific article published on 20 November 2018

Human aplastic anaemia-derived mesenchymal stromal cells form functional haematopoietic stem cell niche in vivo

scientific article published on 02 August 2016

Human umbilical cord blood-borne fibroblasts contain marrow niche precursors that form a bone/marrow organoid in vivo.

scientific article

Hurler Disease Bone Marrow Stromal Cells Exhibit Altered Ability to Support Osteoclast Formation

scientific article published on 02 March 2012

IDUA mutational profiling of a cohort of 102 European patients with mucopolysaccharidosis type I: identification and characterization of 35 novel α-L-iduronidase (IDUA) alleles.

scientific article

IKZF1 status as a prognostic feature in BCR-ABL1-positive childhood ALL.

scientific article

IKZF1plus Defines a New Minimal Residual Disease-Dependent Very-Poor Prognostic Profile in Pediatric B-Cell Precursor Acute Lymphoblastic Leukemia

scientific article published on 2 March 2018

Ictal hypoxemia: A systematic review and meta-analysis

Identical EP300 variant leading to Rubinstein–Taybi syndrome with different clinical and immunologic phenotype

scientific article published on 9 March 2022

Identification Of Low Risk Group In Infants With Acute Lymphoblastic Leukemia By Flow Cytometric Minimal Residual Disease Measurement At Day 15 Of Interfant-99 and Interfant-06 Protocols Treatment ⬇️

scholarly article

Identification of New Genomic Lesions in Childhood ALL without Known Genetic Aberrations: A Microarray Study of Gene Expression and Genotype Data. ⬇️

scholarly article

Identification of immunophenotypic signatures by clustering analysis in pediatric patients with Philadelphia chromosome-positive acute lymphoblastic leukemia

scientific article published on 01 February 2010

Identification of preleukemic precursors of hyperdiploid acute lymphoblastic leukemia in cord blood

scientific article published on May 2004

Imatinib after induction for treatment of children and adolescents with Philadelphia-chromosome-positive acute lymphoblastic leukaemia (EsPhALL): a randomised, open-label, intergroup study

scientific article

Imatinib treatment of paediatric Philadelphia chromosome-positive acute lymphoblastic leukaemia (EsPhALL2010): a prospective, intergroup, open-label, single-arm clinical trial

scientific article published on 01 December 2018

ImmunoTyper-SR: A Novel Computational Approach for Genotyping Immunoglobulin Heavy Chain Variable Genes Using Short Read Data

conference paper published in 2022

ImmunoTyper-SR: A Novel Computational Approach for Genotyping Immunoglobulin Heavy Chain Variable Genes using Short Read Data

preprint published on 2 February 2022

ImmunoTyper-SR: A computational approach for genotyping immunoglobulin heavy chain variable genes using short-read data

scientific article published on 19 October 2022

Immunogenotype changes prevail in relapses of young children with TEL-AML1-positive acute lymphoblastic leukemia and derive mainly from clonal selection

scientific article published on 01 November 2005

Immunopathological signatures in multisystem inflammatory syndrome in children and pediatric COVID-19

Immunosuppression does not affect human bone marrow mesenchymal stromal cell efficacy after transplantation in traumatized mice brain

scientific article

Immunotherapy of acute leukemia by chimeric antigen receptor-modified lymphocytes using an improved Sleeping Beauty transposon platform

scientific article published on 13 June 2016

Impact of COVID-19 on the Pattern of Access to a Pediatric Emergency Department in the Lombardy Region, Italy

scientific article published on 18 August 2020

Impact of IKZF1 deletions on IKZF1 expression and outcome in Philadelphia chromosome negative childhood BCP-ALL. Reply to "incidence and biological significance of IKZF1/Ikaros gene deletions in pediatric Philadelphia chromosome negative and Philade

scientific article published on December 2013

Impairment of Retinoic Acid Signaling in Cornelia de Lange Syndrome Fibroblasts

scientific article published on 28 July 2017

Improved outcome with hematopoietic stem cell transplantation in a poor prognostic subgroup of infants with mixed-lineage-leukemia (MLL)-rearranged acute lymphoblastic leukemia: results from the Interfant-99 Study

scientific article published on 30 June 2010

In Infant ALL with t(4;11)/MLL-AF4 Multiple and Phenotypically Distinct CD19+ BM Subsets Initiate Leukemia in NOD/SCID Mice..

scientific article published in 2009

In Vitro Comparison of Three Different Chimeric Receptor-modified Effector T-cell Populations for Leukemia Cell Therapy ⬇️

scientific article published on July 1, 2011

In vitro and in vivo model of a novel immunotherapy approach for chronic lymphocytic leukemia by anti-CD23 chimeric antigen receptor

scientific article

Inborn errors of type I IFN immunity in patients with life-threatening COVID-19

scientific article published on 24 September 2020

Increased Frequency of Cells with Activated Ribosomal Protein S6 at Diagnosis Associates with MRD Positivity and Relapse in Childhood BCP ALL ⬇️

scholarly article

Influence of Cranial Radiotherapy on Outcome in Children With Acute Lymphoblastic Leukemia Treated With Contemporary Therapy

scientific article published on 11 January 2016

Infusion of Donor Derived Cytokine Induced Killer Cells May Induce Clinical Remission with Limited GVHD in Patients Relapsing after Allogeneic Stem Cell Transplantation. ⬇️

scholarly article

Integration of genomic and gene expression data of childhood ALL without known aberrations identifies subgroups with specific genetic hallmarks

scientific article

Inter-society consensus document on treatment and prevention of bronchiolitis in newborns and infants

scientific article

Interleukin-17–Producing T-Helper Cells as New Potential Player Mediating Graft-Versus-Host Disease in Patients Undergoing Allogeneic Stem-Cell Transplantation

scientific article published on 01 December 2009

International Laboratory Comparison of Methodologies for Determining Minimal Residual Disease (MRD) in Childhood Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia (Ph+ ALL) ⬇️

scholarly article

Intraperitoneal adoptive transfer of mesenchymal stem cells enhances recovery from acid aspiration acute lung injury in mice

scientific article published on 06 March 2017

Isolation and Characterization of Mesenchymal Stromal Cells Derived from Paediatric Patients with B Acute Lymphoblastic Leukemia ⬇️

scholarly article

Isolation of monocytes from leukapheretic products for large-scale GMP-grade generation of cytomegalovirus-specific T-cell lines by means of an automated elutriation device

scientific article

KIT activating mutations: incidence in adult and pediatric acute myeloid leukemia, and identification of an internal tandem duplication

scientific article published in August 2004

LCK over-expression drives STAT5 oncogenic signaling in PAX5 translocated BCP-ALL patients

scientific article

Late MRD response determines relapse risk overall and in subsets of childhood T-cell ALL: results of the AIEOP-BFM-ALL 2000 study

scientific article

Late mortality and causes of death among 5-year survivors of childhood cancer diagnosed in the period 1960-1999 and registered in the Italian Off-Therapy Registry

scientific article published on 14 February 2019

Lessons after the early management of the COVID-19 outbreak in a pediatric transplant and hemato-oncology center embedded within a COVID-19 dedicated hospital in Lombardia, Italy. Estote parati

scientific article published on 20 April 2020

Linking genomic lesions with minimal residual disease improves prognostic stratification in children with T-cell acute lymphoblastic leukaemia.

scientific article published on 2 June 2013

Location First: Targeting Acute Myeloid Leukemia Within Its Niche

scientific article published on 18 May 2020

Long-term follow up of pediatric Philadelphia positive acute lymphoblastic leukemia treated with the EsPhALL2004 study: high white blood cell count at diagnosis is the strongest prognostic factor

scholarly article by Andrea Biondi et al published January 2019 in Haematologica

Long-term results of high-dose imatinib in children and adolescents with chronic myeloid leukaemia in chronic phase: the Italian experience

scientific article

Long-term results of the AIEOP-ALL-95 Trial for Childhood Acute Lymphoblastic Leukemia: insight on the prognostic value of DNA index in the framework of Berlin-Frankfurt-Muenster based chemotherapy

scientific article published in January 2008

Long-term survivors of childhood cancer: cure and care-the Erice Statement (2006) revised after 10 years (2016)

scientific article published on 26 June 2018

Loss of CBL E3-ligase activity in B-lineage childhood acute lymphoblastic leukaemia

scientific article published on 27 July 2012

Loss of PTEN in Pediatric T-Cell Acute Lymphoblastic Leukemia Patients: Proteomic and Molecular Characterization ⬇️

scholarly article

Low-Dose Lenalidomide Improves CAR-Based Immunotherapy In CLL By Reverting T-Cell Defects In Vivo ⬇️

scholarly article

Lymphoblastic predominance of blastic phase in children with chronic myeloid leukaemia treated with imatinib: A report from the I-CML-Ped Study

scientific article published on 13 August 2020

Magnitude and Dynamics of the T-Cell Response to SARS-CoV-2 Infection at Both Individual and Population Levels

scientific article published on 04 August 2020

Management of Chronic Myeloid Leukemia in Children and Adolescents According to Local Guidelines.the Italian Experience ⬇️

scholarly article

Managing children with chronic myeloid leukaemia (CML): recommendations for the management of CML in children and young people up to the age of 18 years

scientific article published on 30 June 2014

Mass Cytometry Analysis Dissects CRLF2-Driven Signaling Pathways in Childhood B-Cell Precursor Acute Lymphoblastic Leukemia (BCP-ALL) ⬇️

scholarly article

Maturation signatures of conventional dendritic cell subtypes in COVID-19 suggest direct viral sensing

scientific article published on 01 October 2021

Mechanism of Altered Nucleo-Cytoplasmic Traffic of Nucleophosmin in Acute Myelogenous Leukemia Carrying Exon-12 NPM Mutations (NPMc+ AML). ⬇️

scholarly article

Mesenchymal Stromal Cell-Derived PTX3 Promotes Wound Healing via Fibrin Remodeling

scientific article published in January 2016

Mesenchymal stromal cell-secreted chemerin is a novel immunomodulatory molecule driving the migration of ChemR23-expressing cells

scientific article published on 6 December 2016

Mesenchymal stromal cells do not increase the risk of viral reactivation nor the severity of viral events in recipients of allogeneic stem cell transplantation

scientific article

Mesenchymal stromal cells from Shwachman-Diamond syndrome patients fail to recreate a bone marrow niche in vivo and exhibit impaired angiogenesis

scientific article published on 16 May 2018

MiR-125b Cooperates with BCR-ABL and Enhances Therapy Resistance in Childhood Ph+ ALL ⬇️

scholarly article

Minimal residual disease as a surrogate marker for risk assignment to ALL patients

scientific article published on September 2003

Minimal residual disease before and after transplantation for childhood acute lymphoblastic leukaemia: is there any room for intervention?

scientific article published on 01 February 2014

Modeling Cornelia de Lange syndrome in vitro and in vivo reveals a role for cohesin complex in neuronal survival and differentiation

scientific article published on 01 January 2019

Modulation of antigen expression in B-cell precursor acute lymphoblastic leukemia during induction therapy is partly transient: evidence for a drug-induced regulatory phenomenon. Results of the AIEOP-BFM-ALL-FLOW-MRD-Study Group

scientific article published on 01 May 2010

Molecular Pathways and Respiratory Involvement in Lysosomal Storage Diseases ⬇️

scientific article published on 15 January 2019

Molecular characterization of a new recombination of the SIL/TAL-1 locus in a child with T-cell acute lymphoblastic leukaemia

scientific article (publication date: September 2002)

Molecular monitoring of childhood acute lymphoblastic leukemia using antigen receptor gene rearrangements and quantitative polymerase chain reaction technology.

scientific article

Molecular remission induced by gemtuzumab ozogamicin associated with donor lymphocyte infusions in t(4;11) acute lymphoblastic leukemia relapsed after transplantation

scientific article published on 01 November 2003

Molecular response to treatment redefines all prognostic factors in children and adolescents with B-cell precursor acute lymphoblastic leukemia: results in 3184 patients of the AIEOP-BFM ALL 2000 study

scientific article published on 12 February 2010

Monitoring minimal residual disease using chromosomal translocations in childhood ALL.

scientific article

Monitoring of minimal residual disease in leukemia, advantages and pitfalls

scientific article published on January 2006

Monokine production by microglial cell clones

scientific article published on August 1989

Monozygotic Twins with Childhood ALL Demonstrate Prenatal Origin of the Philadelphia Chromosome and Post-Natal Ikaros Deletion. ⬇️

scholarly article

Multicenter analysis of neutrophil extracellular trap dysregulation in adult and pediatric COVID-19

scientific article published in 2022

Multivariate Analysis Reveals a miRNA Profile Correlated To Karyotype and Outcome In Pediatric B-Cell Precursor ALL ⬇️

scholarly article

Mutations in exon 2 of GATA1 are early events in megakaryocytic malignancies associated with trisomy 21

scientific article (publication date: August 2003)

Mutations of JAK2 in acute lymphoblastic leukaemias associated with Down's syndrome

scientific article published on 19 September 2008

NIPBL: a new player in myeloid cell differentiation

scientific article published on 10 January 2019

Neonatal bone marrow transplantation prevents bone pathology in a mouse model of mucopolysaccharidosis type I.

scientific article

Neonatal cellular and gene therapies for mucopolysaccharidoses: the earlier the better?

scientific article published on 17 November 2015

Neonatal combination therapy improves some of the clinical manifestations in the Mucopolysaccharidosis type I murine model

scientific article published on 11 May 2020

Neonatal umbilical cord blood transplantation halts skeletal disease progression in the murine model of MPS-I.

scientific article published on 25 August 2017

New advances in leukaemia immunotherapy by the use of Chimeric Artificial Antigen Receptors (CARs): state of the art and perspectives for the near future ⬇️

scientific article published on September 22, 2011

New policies to address the global burden of childhood cancers

scientific article published on 20 February 2013

New susceptibility loci for severe COVID-19 by detailed GWAS analysis in European populations

scholarly article published 23 July 2021

Noonan Syndrome Peripheral Blood Cells Show Enhanced Spontaneous Colonies Growth In Vitro and Hyperactive JAK and RAS Intracellular Signalling Pathways ⬇️

scholarly article

Novel activating mutations lacking cysteine in type I cytokine receptors in acute lymphoblastic leukemia

scientific article published in May 2014

Nucleophosmin mutations in childhood acute myelogenous leukemia with normal karyotype

scientific article published on 03 May 2005

Optimal response to thalidomide in a patient with thalassaemia major resistant to conventional therapy

scientific article

Optimal response to thalidomide in a patient with thalassaemia major resistant to conventional therapy.

scientific article published in July 2010

Oral Nutritional Supplementation in Children Treated for Cancer in Low- and Middle-Income Countries Is Feasible and Effective: the Experience of the Children's Hospital Manuel De Jesus Rivera "La Mascota" in Nicaragua.

scientific article published on 23 June 2018

Outcome of Infants Younger Than 1 Year With Acute Lymphoblastic Leukemia Treated With the Interfant-06 Protocol: Results From an International Phase III Randomized Study

scientific article published on 08 July 2019

Outcome of Infants Younger Than 1 Year with Acute Lymphoblastic Leukemia Treated with the Interfant-06 Protocol; Results from an International Randomised Study ⬇️

scholarly article

Outcome of adolescent patients with acute lymphoblastic leukaemia aged 10-14 years as compared with those aged 15-17 years: Long-term results of 1094 patients of the AIEOP-BFM ALL 2000 study

scientific article published on 17 October 2019

Outcome of congenital acute lymphoblastic leukemia treated on the Interfant-99 protocol.

scientific article

Outcome of very late relapse in children with acute lymphoblastic leukemia

scientific article published on 01 April 2004

Outcomes of paediatric patients with B-cell acute lymphocytic leukaemia with ABL-class fusion in the pre-tyrosine-kinase inhibitor era: a multicentre, retrospective, cohort study

scientific article published on 22 December 2020

PACSIN2 rs2413739 influence on thiopurine pharmacokinetics: validation studies in pediatric patients

scientific article published on 03 December 2019

PAX5 Fusion Genes Activate The STAT5 Signaling Pathway Through Lck Over-Expression ⬇️

scholarly article

PAX5/TEL Causes Down Modulation of B-Lineage Specific Genes, and Enhances Migration to CXCL12 in preBI Cells. ⬇️

scholarly article

PAX5/TEL Exhibits a Dominant-Negative Role by Inhibiting the Expression of Genes Involved in BCR Signalling and Suppressing the Binding of Wild Type PAX5 to Its Direct Target Gene CD79A (mb-1) in a human Pre-B ALL Cell Line. ⬇️

scholarly article

PAX5/TEL Has An Opposite Dominant Effect on Endogenous PAX5, Affecting Its Transcriptional Regulation, B Cell Adhesion and BCR Signaling In Murine Pre-BI Cells ⬇️

scholarly article

PAX5/TEL acts as a transcriptional repressor causing down-modulation of CD19, enhances migration to CXCL12, and confers survival advantage in pre-BI cells

scientific article published on 01 January 2008

PCR Technology to Identify Minimal Residual Disease

scientific article published on 01 January 2021

PTX3 as a Potential Novel Tool for the Diagnosis and Monitoring of Pulmonary Fungal Infections in Immuno-compromised Pediatric Patients

Partial duplication of the PARK2 gene in a child with developmental delay and her normal mother: A second report ⬇️

scientific article published on June 6, 2013

Patient perspectives on the acceptability of mHealth technology for remote measurement and management of epilepsy: A qualitative analysis

scientific article published on 24 June 2019

Pentraxin 3 plasma levels at graft-versus-host disease onset predict disease severity and response to therapy in children given haematopoietic stem cell transplantation

scientific article

Pentraxin-3: An Easily Measurable Soluble Factor to Improve Post-Transplant Graft Versus Host Disease Monitoring and Management. ⬇️

scholarly article

Peripheral blood progenitor cell collection in chronic myeloid leukemia patients with complete cytogenetic response after treatment with imatinib mesylate

scientific article published on July 2005

Pharmacodynamic effects in the cerebrospinal fluid of rats after intravenous administration of different asparaginase formulations

scientific article

Pharmacokinetic profile of imatinib mesylate and N-desmethyl-imatinib (CGP 74588) in children with newly diagnosed Ph+ acute leukemias

scientific article published on 3 June 2008

Phase II Study of Sequential Infusion of Donor Lymphocyte Infusion and Cytokine-Induced Killer Cells for Patients Relapsed after Allogeneic Hematopoietic Stem Cell Transplantation.

scientific article published on 13 July 2017

Phenotypical and Functional Characterization of Mesenchymal Stem Cells Derived From Patients Affected by Schwachman-Diamond Syndrome

scientific article published in 2011

Philadelphia-Like Signature In Childhood Acute Lymphoblastic Leukemia: The AIEOP Experience ⬇️

scholarly article

Platelet-lysate-Expanded Mesenchymal Stromal Cells as a Salvage Therapy for Severe Resistant Graft-versus-Host Disease in a Pediatric Population

scientific article published on 27 March 2010

Potential use of CD40 ligand for immunotherapy of childhood B-cell precursor acute lymphoblastic leukaemia

scientific article published in September 2004

Pre-ictal heart rate changes: A systematic review and meta-analysis.

scientific article published on 8 January 2018

Preclinical Efficacy and Safety of CD19CAR Cytokine-Induced Killer Cells Transfected with Sleeping Beauty Transposon for the Treatment of Acute Lymphoblastic Leukemia.

scientific article

Predictive value of minimal residual disease in Philadelphia-chromosome-positive acute lymphoblastic leukemia treated with imatinib in the European intergroup study of post-induction treatment of Philadelphia-chromosome-positive acute lymphoblastic l

scholarly article by Giovanni Cazzaniga et al published January 2018 in Haematologica

Prednisone induces immunophenotypic modulation of CD10 and CD34 in nonapoptotic B-cell precursor acute lymphoblastic leukemia cells.

scientific article

Prevalence and Prognostic Impact of CEBPA mutations in Children with AML Treated with the AIEOP-LAM 2002/01 Protocol. ⬇️

scholarly article

Pro-inflammatory cytokines favor the emergence of ETV6-RUNX1-positive pre-leukemic cells in a model of mesenchymal niche

scientific article published on 02 March 2020

Prognostic Value of Immunophenotype In Infant ALL – Results of the INTERFANT'99 Study ⬇️

scholarly article

Prognostic discrimination based on the EUTOS long term survival score within the international registry for chronic myeloid leukemia in children and adolescents

scientific article

Prognostic value of minimal residual disease measured by flow-cytometry in two cohorts of infants with acute lymphoblastic leukemia treated according to either MLL-Baby or Interfant protocols

scientific article published on 12 June 2020

Prospective molecular monitoring of BCR/ABL transcript in children with Ph+ acute lymphoblastic leukaemia unravels differences in treatment response

scientific article published in November 2002

Protocol II vs protocol III given twice during reinduction therapy in children with medium-risk ALL.

scientific article published on 22 September 2017

Protocol-based treatment for children with cancer in low income countries in Latin America: a report on the recent meetings of the Monza International School of Pediatric Hematology/Oncology (MISPHO)--part II

scientific article published on 01 April 2007

Protumoral role of monocytes in human B-cell precursor acute lymphoblastic leukemia: involvement of the chemokine CXCL10.

scientific article

Purified Peripheral Autologous Stem Cell Transplant Versus Conventional Chemotherapy for Childhood Low Risk Relapsed Acute Lymphoblastic Leukemia. ⬇️

scholarly article

Quantitative Detection of NPM1 Mutations as Marker of Minimal Residual Disease (MRD) in the Large Majority of AML with Normal Karyotype. ⬇️

scholarly article

Quiescent leukaemic cells account for minimal residual disease in childhood lymphoblastic leukaemia

scientific article

RAG-mediated recombination is the predominant driver of oncogenic rearrangement in ETV6-RUNX1 acute lymphoblastic leukemia

scientific article

Randomized post-induction and delayed intensification therapy in high-risk pediatric acute lymphoblastic leukemia: long-term results of the international AIEOP-BFM ALL 2000 trial

scientific article published on 5 December 2019

Real-Life Management of Children and Adolescents with Chronic Myeloid Leukemia: The Italian Experience

scientific article published on 18 September 2018

Reconstitution of lymphocyte subpopulations in children with inherited metabolic storage diseases after haematopoietic cell transplantation

scientific article published on 01 July 2005

Redirecting T cells with Chimeric Antigen Receptor (CAR) for the treatment of childhood acute lymphoblastic leukemia

scientific article published on 23 August 2017

Reduced Intensity Delayed Intensification in Standard-Risk Patients Defined By Minimal Residual Disease in Childhood Acute Lymphoblastic Leukemia: Results of an International Randomized Trial in 1164 Patients (Trial AIEOP-BFM ALL 2000) ⬇️

scholarly article

Reduced-Intensity Delayed Intensification in Standard-Risk Pediatric Acute Lymphoblastic Leukemia Defined by Undetectable Minimal Residual Disease: Results of an International Randomized Trial (AIEOP-BFM ALL 2000).

scientific article published on 17 November 2017

Regulatory T cells and extracorporeal photochemotherapy: correlation with clinical response and decreased frequency of proinflammatory T cells.

scientific article published in May 2009

Relapses and treatment-related events contributed equally to poor prognosis in children with ABL-class fusion positive B-cell acute lymphoblastic leukemia treated according to AIEOP-BFM protocols

scientific article published on 10 October 2019

Remote Assessment of Disease and Relapse in Epilepsy: Protocol for a Multicenter Prospective Cohort Study

scientific article published on 16 December 2020

Repeated infusions of donor-derived cytokine-induced killer cells in patients relapsing after allogeneic stem cell transplantation: a phase I study

scientific article published in July 2007

Response to High Dose Imatinib and Long-Term Outcome in Children and Adolescents with Previously Untreated Chronic Myeloid Leukemia in Chronic Phase. the Italian Experience ⬇️

scholarly article

Results and outcome of intermittent imatinib (ON/OFF schedule) in children and adolescents with chronic myeloid leukaemia

scientific article published on 22 February 2020

Results of a multicenter universal newborn screening program for sickle cell disease in Italy: A call to action

scientific article published on 05 February 2019

Results of minimal residual disease (MRD) evaluation and MRD-based treatment stratification in childhood ALL.

scientific article

Results of the AIEOP AML 2002/01 multicenter prospective trial for the treatment of children with acute myeloid leukemia

scientific article published on 14 May 2013

Results of the AIEOP-BFM ALL 2000 Study for Childhood Acute Lymphoblastic Leukemia IN AIEOP High Risk Patients. ⬇️

scholarly article

Revised recommendations of the International Working Group for Diagnosis, Standardization of Response Criteria, Treatment Outcomes, and Reporting Standards for Therapeutic Trials in Acute Myeloid Leukemia

scientific article published on December 2003

Rings and Bricks: Expression of Cohesin Components is Dynamic during Development and Adult Life

scientific article published in February 2018

Risk factors for relapse in childhood acute lymphoblastic leukemia: prediction and prevention

scientific article

Risk of relapse of childhood acute lymphoblastic leukemia is predicted by flow cytometric measurement of residual disease on day 15 bone marrow.

scientific article published on 5 October 2009

Rituximab Unveils Hypogammaglobulinemia and Immunodeficiency in Children with Autoimmune Cytopenia

scientific article published on 02 August 2019

Rituximab induces different but overlapping sets of genes in human B-lymphoma cell lines

scientific article published on 23 September 2004

Role Of Long Pentraxin 3 (PTX3) In Wound Closure Induced By Bone Marrow-Derived Mesenchymal Stromal Cells ⬇️

scholarly article

Role of CXCR4-mediated bone marrow colonization in CNS infiltration by T cell acute lymphoblastic leukemia

scientific article

Role of the Histone Deacetylase Inhibitor Givinostat (ITF2357) in Treatment of CRLF2 Rearranged Acute Lymphoblastic Leukemia ⬇️

scholarly article

Role of treatment intensification in infants with acute lymphoblastic leukemia: results of two consecutive AIEOP studies.

scientific article published on 15 March 2006

SENTIERI KIDS: protecting health and preventing childhood cancer in contaminated sites

scientific article published on March 1, 2013

SRC/ABL inhibition disrupts CRLF2-driven signaling to induce cell death in B-cell acute lymphoblastic leukemia.

scientific article published in May 2018

STAT5 Phosphorylation Status by Flow Cytometry Is a Rapid and Reliable Tool for Diagnosis and Follow-up of Juvenile Myelomonocytic Leukemia ⬇️

scholarly article

Seizure forecasting using minimally invasive, ultra‐long‐term subcutaneous EEG: Generalizable cross‐patient models

scientific article published in 2022

Seizure forecasting using minimally invasive, ultra‐long‐term subcutaneous electroencephalography: Individualized intrapatient models

scientific article published in 2022

Selective homing of CAR-CIK cells to the bone marrow niche enhances control of the Acute Myeloid Leukemia burden

scientific article published in 2023

Sensitivity to imatinib but low frequency of the TEL/PDGFRbeta fusion protein in chronic myelomonocytic leukemia

scientific article published on April 2003

Single-Cell Profiling of Signal Transduction Pathways in Pediatric T-Cell Acute Lymphoblastic Leukemia By Mass Cytometry:Dissecting JAK/STAT and PI3K/Akt/mTOR Active Signalling

scientific article published in 2020

Single-cell developmental classification of B cell precursor acute lymphoblastic leukemia at diagnosis reveals predictors of relapse

scientific article published on 5 March 2018

Single-cell profiling of pediatric T-cell acute lymphoblastic leukemia: Impact of PTEN exon 7 mutation on PI3K/Akt and JAK-STAT signaling pathways

scientific article published on 01 June 2020

Sleeping Beauty Modified CAR+ Lymphocytes Engraft and Exhibit Anti-Tumor Activity in Patient-Derived Xenograft Models of Acute Lymphoblastic Leukemia ⬇️

scholarly article

Sleeping Beauty-engineered CAR T cells achieve anti-leukemic activity without severe toxicities

scientific article published on 11 August 2020

Somatic PTPN11 mutations in childhood acute myeloid leukaemia

scientific article

Somatically acquired JAK1 mutations in adult acute lymphoblastic leukemia

scientific article

Specific Targeting of Acute Myeloid Leukemia By the Use of Non-Virally Engineered CIK (Cytokine-Induced Killer) Cells Expressing the Anti-CD33 Chimeric Antigen Receptor (CAR) ⬇️

scholarly article

Spiritual support for adolescent cancer patients: a survey of pediatric oncology centers in Italy and Spain

scientific article

Standardization of flow cytometric minimal residual disease evaluation in acute lymphoblastic leukemia: Multicentric assessment is feasible.

scientific article published in November 2008

Suppressors and activators of JAK-STAT signaling at diagnosis and relapse of acute lymphoblastic leukemia in Down syndrome

scientific article published in May 2017

Switch to Subsequent Line of Treatment in Children and Adolescents with Chronic Myeloid Leukemia (CML) Treated with Imatinib: Experience of the International Registry for Chronic Myeloid Leukemia in Children and Adolescents (I-CML-Ped Study) ⬇️

scholarly article

TCR Redirected T Cells for Cancer Treatment: Achievements, Hurdles, and Goals

scientific article published on 03 September 2020

TEL-AML1 Affects the Regulation of Cytoskeleton and Causes Alteration In Cellular Adhesive and Migratory Properties In An In Vitro Model of Pre-Leukemia. ⬇️

scholarly article

TEL/AML1 Rearrangement Is Rare in Children with Acute Lymphoblastic Leukemia (ALL) and Down Syndrome (DS). Presenting Features and Treatment Outcome in the Experience of the Associazione Italiana Ematologia Oncologia Pediatrica (AIEOP). ⬇️

scholarly article

TEL/ARG induces cytoskeletal abnormalities in 293T cells.

scientific article

TNFRSF13C (BAFFR) positive blasts persist after early treatment and at relapse in childhood B-cell precursor acute lymphoblastic leukaemia

scientific article published in June 2017

Tailoring treatment strategy for acute promyelocytic leukemia in low-income countries.

scientific article published in September 2009

Targeting CD33 in Chemoresistant AML Patient-Derived Xenografts by CAR-CIK Cells Modified with an Improved SB Transposon System

scientific article published on 30 May 2020

Targeting a Specific Glycosylated Epitope of CD43 with a New Humanized Monoclonal Antibody for the Treatment of Pediatric and Adult T-Cell Acute Lymphoblastic Leukemia (T-ALL) ⬇️

scholarly article

Targeting of acute myeloid leukaemia by cytokine-induced killer cells redirected with a novel CD123-specific chimeric antigen receptor.

scientific article

The ABO blood group locus and a chromosome 3 gene cluster associate with SARS-CoV-2 respiratory failure in an Italian-Spanish genome-wide association analysis

scientific article (preprint)

The Chemerin/ChemR23 Axis Plays a Pivotal Role in the Pathogenesis of Intestinal Damage in a Murine Model of Graft Versus Host Disease ⬇️

scholarly article

The EuroChimerism Concept for a Standardized Approach to Chimerism Analysis Following Allogeneic Stem Cell Transplantation. ⬇️

scholarly article

The International Registry for Chronic Myeloid Leukemia (CML) in Children and Adolescents (I-CML-Ped-Study): Objectives and Preliminary Results ⬇️

scholarly article

The Italian Registry for Primary Immunodeficiencies (Italian Primary Immunodeficiency Network; IPINet): Twenty Years of Experience (1999-2019)

scientific article published on 15 August 2020

The SIOPE strategic plan: A European cancer plan for children and adolescents

The Transition from Childhood to Adulthood in Chronic Immune Thrombocytopenia Patients: Clinical Management and the Role of Splenectomy and Thrombopoietin Receptor Agonists in a Single Center Experience ⬇️

scholarly article

The effects of propofol and ketamine on the cytokine levels of children with acute lymphoblastic leukemia

scientific article published in October 2013

The endocannabinoid anandamide neither impairs in vitro T-cell function nor induces regulatory T-cell generation.

scientific article published on November 2008

The new frame for Mucopolysaccharidoses

scientific article published on 16 November 2018

The presence of mutated and deleted PTEN is associated with an increased risk of relapse in childhood T cell acute lymphoblastic leukaemia treated with AIEOP-BFM ALL protocols

scientific article published on 25 June 2018

The risk of COVID-19 death is much greater and age dependent with type I IFN autoantibodies

scientific article published on 16 May 2022

The sensitivity of acute lymphoblastic leukemia cells carrying the t(12;21) translocation to campath-1H-mediated cell lysis.

scientific article published on March 2006

The silent mutational landscape of infant MLL-AF4 pro-B acute lymphoblastic leukemia.

scientific article published on 26 July 2013

The thirteenth international childhood acute lymphoblastic leukemia workshop report: La Jolla, CA, USA, December 7–9, 2011 ⬇️

scientific article published on September 28, 2012

The washouts of discarded bone marrow collection bags and filters are a very abundant source of hMSCs.

scientific article

Three novel fusion transcripts of the paired box 5 gene in B-cell precursor acute lymphoblastic leukemia

scientific article published on 10 October 2014

Thrombocytopenia and Cornelia de Lange syndrome: Still an enigma?

scientific article

Time point-dependent concordance of flow cytometry and real-time quantitative polymerase chain reaction for minimal residual disease detection in childhood acute lymphoblastic leukemia

scientific article

Transposon-Based CAR T Cells in Acute Leukemias: Where are We Going?

scientific article published on 27 May 2020

Treatment of graft versus host disease with mesenchymal stromal cells: a phase I study on 40 adult and pediatric patients

scientific article published on 7 December 2013

Two cases of hepatic adenomas in patients with Wolf-Hirschhorn syndrome: a new rare complication?

scientific article published on 21 May 2013

Tyrosine kinase inhibitors in BCR-ABL positive acute lymphoblastic leukemia

scientific article published in March 2015

Understanding the Immunomodulatory Effect of Mesenchymal Stem Cell Infused In Transplanted Patients with Steroid-Refractory GvHD ⬇️

scholarly article

Unraveling the Efficacy and Safety Profiles of Anti-CD123 Chimeric Antigen Receptors (CARs) in a Model of Acute Myeloid Leukemia Immunotherapy By Investigating CAR Binding Affinity and Density Variables ⬇️

scholarly article

Validation of Minimal Residual Disease as Surrogate Endpoint for Event-Free Survival in Childhood Acute Lymphoblastic Leukemia

scientific article published on 01 October 2018

WT1 gene expression: useful marker for minimal residual disease in childhood myelodysplastic syndromes and juvenile myelo-monocytic leukemia?

scientific article published in July 2004

Wearable technology in epilepsy: The views of patients, caregivers, and healthcare professionals

What is the relevance of Ikaros gene deletions as a prognostic marker in pediatric Philadelphia-negative B-cell precursor acute lymphoblastic leukemia?

scientific article published on 12 April 2013

Williams syndrome and mature B-Leukemia: A random association?

scientific article published on 19 October 2016

X-linked recessive TLR7 deficiency in ~1% of men under 60 years old with life-threatening COVID-19

scholarly article by Takaki Asano published in 2021

“There's no Reason why”: A Campaign to Raise Cancer Awareness among Adolescents

scientific article published on 26 March 2016

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