List of works - Tae-Sung Koo

Comparative single-dose pharmacokinetics of sildenafil after oral and rectal administration in healthy beagle dogs

scientific article published on 24 September 2018

Comparison of body surface area-based and weight-based dosing format for oral prednisolone administration in small and large-breed dogs.

scientific article published in September 2017

Comparison of pharmacokinetics of loxoprofen and its active metabolites after an intravenous, intramuscular, and oral administration of loxoprofen in rats: evidence for extrahepatic metabolism.

scientific article published in October 2005

Development and Evaluation of Raloxifene-Hydrochloride-Loaded Supersaturatable SMEDDS Containing an Acidifier

scientific article published on 29 June 2018

Development and validation of a liquid chromatography-tandem mass spectrometry method for the assay of tafamidis in rat plasma: Application to a pharmacokinetic study in rats.

scientific article published on 10 January 2017

Development of a LC-MS/MS method for the determination of CKD-712 in rat plasma: Application to a pharmacokinetic study in rats

scientific article published on 08 July 2017

Discovery and optimization of ATX inhibitors via modeling, synthesis and biological evaluation

scientific article published on 17 February 2018

Discovery of Tyk2 inhibitors via the virtual site-directed fragment-based drug design

scientific article published on 21 July 2015

Discovery of non-LBD inhibitor for androgen receptor by structure-guide design.

scientific article published on 3 May 2013

Enhanced Solubility, Dissolution and Lipase Inhibition of a Self-Nanoemulsifying Drug Delivery System Containing Orlistat

scientific article published on 01 February 2019

Hair-growth-promoting effect of conditioned medium of high integrin α6 and low CD 71 (α6bri/CD71dim) positive keratinocyte cells.

scientific article

Liquid chromatography-tandem mass spectrometry of recombinant human extracellular superoxide dismutase (rhSOD3) in mouse plasma and its application to pharmacokinetic study

scientific article published on 15 November 2018

Orlistat-loaded solid SNEDDS for the enhanced solubility, dissolution, and in vivo performance

scientific article published on 05 November 2018

Pharmacokinetic study of meropenem in healthy beagle dogs receiving intermittent hemodialysis.

scientific article published on 15 June 2016

Pharmacokinetics and Acid Suppressant Efficacy of Esomeprazole after Intravenous, Oral, and Subcutaneous Administration to Healthy Beagle Dogs.

scientific article

Pharmacokinetics and pharmacodynamics of intravenous esomeprazole at 2 different dosages in dogs.

scientific article published on 13 December 2018

Pharmacokinetics of enzalutamide, an anti-prostate cancer drug, in rats

scientific article

Pharmacokinetics of lurasidone, a novel atypical anti-psychotic drug, in rats.

scientific article published on 13 August 2011

Pharmacokinetics of tafamidis, a transthyretin amyloidosis drug, in rats.

scientific article published on 14 August 2017

Pharmacokinetics, brain distribution, and plasma protein binding of the antiepileptic drug lacosamide in rats ⬇️

scientific article published on December 31, 2011

Protective effect of RIPK1-inhibitory compound in in vivo models for retinal degenerative disease

scientific article published on 27 November 2018

Quantification of clotiazepam in human plasma by gas chromatography-mass spectrometry.

scientific article published on 6 March 2006

Quantitative determination of enzalutamide, an anti-prostate cancer drug, in rat plasma using liquid chromatography-tandem mass spectrometry, and its application to a pharmacokinetic study

scientific article published on 15 January 2014

Simultaneous quantification of methylene blue and its major metabolite, azure B, in plasma by LC-MS/MS and its application for a pharmacokinetic study.

scientific article

Subacute toxicity evaluation of KR-33493, FAF1 inhibitor for a new anti-parkinson's disease agent, after oral administration in rats and dogs

scientific article published on 21 September 2016

Systemic optimization and structural evaluation of quinoline derivatives as transthyretin amyloidogenesis inhibitors.

scientific article

The pharmacokinetics of the β2-adrenoceptor agonist, tulobuterol, in Beagle dogs following transdermal and intravenous administration.

scientific article published on 13 October 2015

List of works by Tae-Sung Koo

Comparative single-dose pharmacokinetics of sildenafil after oral and rectal administration in healthy beagle dogs

Comparison of body surface area-based and weight-based dosing format for oral prednisolone administration in small and large-breed dogs.

Comparison of pharmacokinetics of loxoprofen and its active metabolites after an intravenous, intramuscular, and oral administration of loxoprofen in rats: evidence for extrahepatic metabolism.

Development and Evaluation of Raloxifene-Hydrochloride-Loaded Supersaturatable SMEDDS Containing an Acidifier

Development and validation of a liquid chromatography-tandem mass spectrometry method for the assay of tafamidis in rat plasma: Application to a pharmacokinetic study in rats.

Development of a LC-MS/MS method for the determination of CKD-712 in rat plasma: Application to a pharmacokinetic study in rats

Discovery and optimization of ATX inhibitors via modeling, synthesis and biological evaluation

Discovery of Tyk2 inhibitors via the virtual site-directed fragment-based drug design

Discovery of non-LBD inhibitor for androgen receptor by structure-guide design.

Enhanced Solubility, Dissolution and Lipase Inhibition of a Self-Nanoemulsifying Drug Delivery System Containing Orlistat

Hair-growth-promoting effect of conditioned medium of high integrin α6 and low CD 71 (α6bri/CD71dim) positive keratinocyte cells.

Liquid chromatography-tandem mass spectrometry of recombinant human extracellular superoxide dismutase (rhSOD3) in mouse plasma and its application to pharmacokinetic study

Orlistat-loaded solid SNEDDS for the enhanced solubility, dissolution, and in vivo performance

Pharmacokinetic study of meropenem in healthy beagle dogs receiving intermittent hemodialysis.

Pharmacokinetics and Acid Suppressant Efficacy of Esomeprazole after Intravenous, Oral, and Subcutaneous Administration to Healthy Beagle Dogs.

Pharmacokinetics and pharmacodynamics of intravenous esomeprazole at 2 different dosages in dogs.

Pharmacokinetics of enzalutamide, an anti-prostate cancer drug, in rats

Pharmacokinetics of lurasidone, a novel atypical anti-psychotic drug, in rats.

Pharmacokinetics of tafamidis, a transthyretin amyloidosis drug, in rats.

Pharmacokinetics, brain distribution, and plasma protein binding of the antiepileptic drug lacosamide in rats ⬇️

Protective effect of RIPK1-inhibitory compound in in vivo models for retinal degenerative disease

Quantification of clotiazepam in human plasma by gas chromatography-mass spectrometry.

Quantitative determination of enzalutamide, an anti-prostate cancer drug, in rat plasma using liquid chromatography-tandem mass spectrometry, and its application to a pharmacokinetic study

Simultaneous quantification of methylene blue and its major metabolite, azure B, in plasma by LC-MS/MS and its application for a pharmacokinetic study.

Subacute toxicity evaluation of KR-33493, FAF1 inhibitor for a new anti-parkinson's disease agent, after oral administration in rats and dogs

Systemic optimization and structural evaluation of quinoline derivatives as transthyretin amyloidogenesis inhibitors.

The pharmacokinetics of the β2-adrenoceptor agonist, tulobuterol, in Beagle dogs following transdermal and intravenous administration.