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List of works by Francois Mercier

A Model-Based Meta-analysis to Compare Efficacy and Tolerability of Tramadol and Tapentadol for the Treatment of Chronic Non-Malignant Pain.

scientific article

A continuous-time multistate Markov model to describe the occurrence and severity of diarrhea events in metastatic breast cancer patients treated with lumretuzumab in combination with pertuzumab and paclitaxel

scientific article published on 18 June 2018

Association Between Tumor Size Kinetics and Survival in Patients With Urothelial Carcinoma Treated With Atezolizumab: Implication for Patient Follow-Up

scientific article published on 05 July 2019

Bayesian inference using Hamiltonian Monte-Carlo algorithm for nonlinear joint modeling in the context of cancer immunotherapy

scientific article published on 08 October 2020

Characterization of dose-response for count data using a generalized MCP-Mod approach in an adaptive dose-ranging trial.

scientific article published on 17 June 2015

Estimating time to disease progression comparing transition models and survival methods--an analysis of multiple sclerosis data

scientific article

Evaluation of tumor size response metrics to predict survival in oncology clinical trials.

scientific article published on 13 January 2014

Exposure-response analysis of alectinib in crizotinib-resistant ALK-positive non-small cell lung cancer.

scientific article published on 10 May 2018

From waterfall plots to spaghetti plots in early oncology clinical development

scientific article published on 03 April 2019

Longitudinal analysis of organ-specific tumor lesion sizes in metastatic colorectal cancer patients receiving first line standard chemotherapy in combination with anti-angiogenic treatment

scientific article published on 31 August 2020

Model-based drug development in oncology: what's next?

scientific article published in April 2013

Model-based prediction of progression-free survival in patients with first-line renal cell carcinoma using week 8 tumor size change from baseline.

scientific article published on 28 July 2016

Modeling and simulations relating overall survival to tumor growth inhibition in renal cell carcinoma patients

scientific article

Population pharmacokinetics of fingolimod phosphate in healthy participants.

scientific article published on 22 November 2011

Rivastigmine exposure provided by a transdermal patch versus capsules.

scientific article published in December 2007

Temporal profile of lymphocyte counts and relationship with infections with fingolimod therapy

scientific article published on 15 August 2013

Therapeutically-induced stable disease in oncology early clinical trials

scientific article published on 29 May 2020

Tumor Size and Overall Survival in Patients With Platinum-Resistant Ovarian Cancer Treated With Chemotherapy and Bevacizumab.

scientific article published on 28 May 2019

Using historical control information for the design and analysis of clinical trials with overdispersed count data

scientific article

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