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List of works by Bik-Kwoon Tye

A comprehensive genome-wide map of autonomously replicating sequences in a naive genome

scientific article

A viable allele of Mcm4 causes chromosome instability and mammary adenocarcinomas in mice

scientific article published on 3 December 2006

Alternative mechanisms for coordinating polymerase alpha and MCM helicase

scientific article published on 16 November 2009

Aneuploidy and improved growth are coincident but not causal in a yeast cancer model

scientific article published on 28 July 2009

Budding yeast mcm10/dna43 mutant requires a novel repair pathway for viability ⬇️

scientific article published on 01 May 2003

Computational detection of significant variation in binding affinity across two sets of sequences with application to the analysis of replication origins in yeast

scientific article

Drosophila MCM10 interacts with members of the prereplication complex and is required for proper chromosome condensation

scientific article

Dual functional regulators coordinate DNA replication and gene expression in proliferating cells

scientific article published in September 2004

Erratum: Unusual DNA sequences associated with the ends of yeast chromosomes

scholarly article published in Nature

Evidence for a role of MCM (mini-chromosome maintenance)5 in transcriptional repression of sub-telomeric and Ty-proximal genes in Saccharomyces cerevisiae.

scientific article

Genome-wide hierarchy of replication origin usage in Saccharomyces cerevisiae

scientific article published on 25 July 2006

Humanizing the yeast origin recognition complex

scientific article published on 04 January 2021

Mcm1 binds replication origins

scientific article

Mcm1 promotes replication initiation by binding specific elements at replication origins

scientific article published on July 2004

Mcm10 and Cdc45 cooperate in origin activation in Saccharomyces cerevisiae

scientific article published in July 2004

Mcm10 is required for the maintenance of transcriptional silencing in Saccharomyces cerevisiae

scientific article

Mcm10 mediates the interaction between DNA replication and silencing machineries

scientific article

Mcm3 is polyubiquitinated during mitosis before establishment of the pre-replication complex

scientific article published on 27 August 2002

Mcm7, a Subunit of the Presumptive MCM Helicase, Modulates Its Own Expression in Conjunction with Mcm1 ⬇️

scientific article published on May 7, 2003

Memories of Ray Wu by a colleague

scientific article published in February 2009

Novel DNA binding properties of the Mcm10 protein from Saccharomyces cerevisiae

scientific article

Novel features of ARS selection in budding yeast Lachancea kluyveri

scientific article

Old-fashioned genetic screens give new insights to DNA replication ⬇️

scientific article published on 01 December 2010

Open-ringed structure of the Cdt1-Mcm2-7 complex as a precursor of the MCM double hexamer

scientific article published on 13 February 2017

Ploidy dictates repair pathway choice under DNA replication stress

scientific article

Structural Insight into the MCM double hexamer activation by Dbf4-Cdc7 kinase

scientific article published on 16 March 2022

Structural insights into the Cdt1-mediated MCM2-7 chromatin loading.

scientific article

Structure of the MCM2-7 Double Hexamer and Its Implications for the Mechanistic Functions of the Mcm2-7 Complex

scientific article published in January 2017

Structure of the eukaryotic MCM complex at 3.8 Å

scientific article

Structure of the origin recognition complex bound to DNA replication origin

scientific article published in Nature

The Methanobacterium thermoautotrophicum MCM protein can form heptameric rings

scientific article

Two mcm3 mutations affect different steps in the initiation of DNA replication

scientific article

Unique Roles of the Non-identical MCM Subunits in DNA Replication Licensing

scientific article

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