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List of works by Steven Foung

A Point Mutation Leading to Hepatitis C Virus Escape from Neutralization by a Monoclonal Antibody to a Conserved Conformational Epitope

scientific article

A novel neutralizing human monoclonal antibody broadly abrogates hepatitis C virus infection in vitro and in vivo

scientific article published on 23 October 2017

Affinity maturation of a broadly neutralizing human monoclonal antibody that prevents acute hepatitis C virus infection in mice.

scientific article

Affinity maturation to improve human monoclonal antibody neutralization potency and breadth against hepatitis C virus

scientific article

An anti-H5N1 influenza virus FcDART antibody is a highly efficacious therapeutic agent and prophylactic against H5N1 influenza virus infection

scientific article

Analysis of a Highly Flexible Conformational Immunogenic Domain A in Hepatitis C Virus E2

scientific article

Antibodies to hepatitis C virus in low-risk blood donors: Implications for counseling positive donors ⬇️

scientific article published on December 1, 1991

Antibody Response to Hypervariable Region 1 Interferes with Broadly Neutralizing Antibodies to Hepatitis C Virus

scientific article published on 6 January 2016

Antibody Treatment of Ebola and Sudan Virus Infection via a Uniquely Exposed Epitope within the Glycoprotein Receptor-Binding Site

scientific article published on 4 May 2016

Antibody light chain-catalyzed hydrolysis of a hepatitis C virus peptide

scientific article

Antibody-Dependent Enhancement of Hepatitis C Virus Infection

scientific article (publication date: March 2008)

Antigen-specific proteolysis by hybrid antibodies containing promiscuous proteolytic light chains paired with an antigen-binding heavy chain

scientific article published on 19 June 2009

Antigenicity and Immunogenicity of Differentially Glycosylated Hepatitis C Virus E2 Envelope Proteins Expressed in Mammalian and Insect Cells

scientific article published on 21 March 2019

Breadth of neutralization and synergy of clinically relevant human monoclonal antibodies against HCV genotypes 1a, 1b, 2a, 2b, 2c, and 3a.

scientific article published on 2 October 2014

Broadly neutralizing antibodies from an individual that naturally cleared multiple hepatitis C virus infections uncover molecular determinants for E2 targeting and vaccine design

scientific article published on 17 May 2019

Broadly neutralizing human monoclonal antibodies to the hepatitis C virus E2 glycoprotein

scientific article

CD81 is dispensable for hepatitis C virus cell-to-cell transmission in hepatoma cells

scientific journal article

Characterization of hepatitis C virus recombinants with chimeric E1/E2 envelope proteins and identification of single amino acids in the E2 stem region important for entry

scientific article published on 14 November 2012

Cloning and analysis of a recombinant antigen containing an epitope specific for human T-cell lymphotropic virus type II ⬇️

scientific article published on May 15, 1992

Comprehensive linker-scanning mutagenesis of the hepatitis C virus E1 and E2 envelope glycoproteins reveals new structure-function relationships

scientific article published on 22 June 2011

Conformational Flexibility in the Immunoglobulin-Like Domain of the Hepatitis C Virus Glycoprotein E2.

scientific article

Contrasting roles of mitogen-activated protein kinases in cellular entry and replication of hepatitis C virus: MKNK1 facilitates cell entry

scientific article published on 30 January 2013

Cooperativity in virus neutralization by human monoclonal antibodies to two adjacent regions located at the amino terminus of hepatitis C virus E2 glycoprotein

scientific article published on 24 October 2012

Crystal Structure of a Bivalent Antibody Fab Fragment

scientific article published on 18 November 2020

DC-SIGN and L-SIGN are high affinity binding receptors for hepatitis C virus glycoprotein E2

scientific article

Definition of a Conserved Immunodominant Domain on Hepatitis C Virus E2 Glycoprotein by Neutralizing Human Monoclonal Antibodies

scientific article (publication date: June 2008)

Delineation of an immunodominant and human T-cell lymphotropic virus (HTLV)-specific epitope within the HTLV-I transmembrane glycoprotein ⬇️

scientific article published on August 15, 1995

Designing a B Cell-Based Vaccine against a Highly Variable Hepatitis C Virus

scientific article published in January 2017

Epitope mapping of HTLV envelope seroreactivity in LGL leukaemia ⬇️

scientific article published on May 1, 1998

Experimental Infection of Chimpanzees with Hepatitis G Virus and Genetic Analysis of the Virus ⬇️

scientific article published on April 1, 1998

GBV-C/HGV: A new virus within the Flaviviridae and its clinical implications ⬇️

scientific article published on April 1, 1998

Global mapping of antibody recognition of the hepatitis C virus E2 glycoprotein: Implications for vaccine design

scientific article published on 26 October 2016

Hepatitis C Virus (HCV)-Apolipoprotein Interactions and Immune Evasion and Their Impact on HCV Vaccine Design.

scientific article published on 21 June 2018

Hepatitis C Virus (HCV)-Induced Immunoglobulin Hypermutation Reduces the Affinity and Neutralizing Activities of Antibodies against HCV Envelope Protein

scientific article

Hepatitis C virus E2 has three immunogenic domains containing conformational epitopes with distinct properties and biological functions

scientific article

Hepatitis C virus e2 protein ectodomain is essential for assembly of infectious virions

scientific article

Hepatitis C virus hypervariable region 1 modulates receptor interactions, conceals the CD81 binding site, and protects conserved neutralizing epitopes.

scientific article

Hepatitis C virus induces toll-like receptor 4 expression, leading to enhanced production of beta interferon and interleukin-6

scientific article

Hepatitis C virus vaccine candidates inducing protective neutralizing antibodies

scientific article

Human monoclonal antibodies to a novel cluster of conformational epitopes on HCV E2 with resistance to neutralization escape in a genotype 2a isolate

scientific article

Human monoclonal antibody to hepatitis C virus E1 glycoprotein that blocks virus attachment and viral infectivity

scientific article

Immune responsiveness to the immunodominant recombinant envelope epitopes of human T lymphotropic virus types I and II in diverse geographic populations

scientific article published on November 1, 1992

Immunogenic and Functional Organization of Hepatitis C Virus (HCV) Glycoprotein E2 on Infectious HCV Virions

scientific article

In vitro selection of a neutralization-resistant hepatitis C virus escape mutant

scientific article

In vivo combination of human anti-envelope glycoprotein E2 and -Claudin-1 monoclonal antibodies for prevention of hepatitis C virus infection

scientific article published on 30 December 2018

Interferon-Induced Transmembrane Proteins Mediate Viral Evasion in Acute and Chronic Hepatitis C Virus Infection

scientific article published on 21 June 2019

Isolation of HCV Neutralizing Antibodies by Yeast Display

Isotypic and IgG Subclass Restriction of the Humoral Immune Responses to Human T-Lymphotropic Virus Type-I ⬇️

scientific article published on April 1, 1993

Large granular lymphocyte leukaemia occurring after renal transplantation ⬇️

scientific article published on June 1, 1998

Learning from a clinical cohort for HCV vaccine development

scientific article published on 13 April 2019

Macaque Monoclonal Antibodies Targeting Novel Conserved Epitopes within Filovirus Glycoprotein.

scientific article

Mapping a region of hepatitis C virus E2 that is responsible for escape from neutralizing antibodies and a core CD81-binding region that does not tolerate neutralization escape mutations

scientific article

Modified Western Blot Assay for Confirmation and Differentiation of Human T Cell Lymphotropic Virus Types I and II ⬇️

scientific article published on August 1, 1991

Mutations in Hepatitis C Virus E2 Located outside the CD81 Binding Sites Lead to Escape from Broadly Neutralizing Antibodies but Compromise Virus Infectivity

scientific article (publication date: June 2009)

Mutations that alter use of hepatitis C virus cell entry factors mediate escape from neutralizing antibodies

scientific article published on 10 April 2012

Mutations within a conserved region of the hepatitis C virus E2 glycoprotein that influence virus-receptor interactions and sensitivity to neutralizing antibodies.

scientific article

Native Folding of a Recombinant gpE1/gpE2 Heterodimer Vaccine Antigen from a Precursor Protein Fused with Fc IgG.

scientific article published on 19 October 2016

Naturally selected hepatitis C virus polymorphisms confer broad neutralizing antibody resistance

scientific article

Neutralization resistance of hepatitis C virus can be overcome by recombinant human monoclonal antibodies

scientific article published on 7 August 2013

Neutralizing antibody response to hepatitis C virus

scientific article

Neutralizing human monoclonal antibodies to conformational epitopes of human T-cell lymphotropic virus type 1 and 2 gp46 ⬇️

scientific article published on August 1, 1997

Non-random escape pathways from a broadly neutralizing human monoclonal antibody map to a highly conserved region on the hepatitis C virus E2 glycoprotein encompassing amino acids 412-423

scientific article

Parameters to enhance human hybridoma formation with hypoosmolar electrofusion

scientific article published on July 1, 1991

Preclinical Evaluation of Two Neutralizing Human Monoclonal Antibodies against Hepatitis C Virus (HCV): a Potential Treatment To Prevent HCV Reinfection in Liver Transplant Patients

scientific article (publication date: March 2006)

Recognition of native hepatitis C virus E1E2 heterodimers by a human monoclonal antibody.

scientific article

Rescue of human monoclonal antibody production from an EBV-transformed B cell line by fusion to a human-mouse hybridoma ⬇️

scientific article published on May 11, 1984

SARS-CoV-2 RNAemia in a Healthy Blood Donor 40 Days After Respiratory Illness Resolution

scientific article published on 17 July 2020

Serologic confirmation of simian T-lymphotropic virus type I infection by using immunoassays developed for human T-lymphotropic virus antibody detection ⬇️

scientific article published on April 1, 1992

Seroreactivity to an envelope protein of human T-cell leukemia/lymphoma virus in patients with CD3- (natural killer) lymphoproliferative disease of granular lymphocytes ⬇️

scientific article published on September 1, 1997

Significance of Human T-Lymphotropic Virus Type I Indeterminant Serological Findings among Healthy Individuals ⬇️

scientific article published on January 1, 1991

Structural Basis of HCV Neutralization by Human Monoclonal Antibodies Resistant to Viral Neutralization Escape

scientific article

Structural basis for penetration of the glycan shield of hepatitis C virus E2 glycoprotein by a broadly neutralizing human antibody

scientific article

Structural elucidation of critical residues involved in binding of human monoclonal antibodies to hepatitis C virus E2 envelope glycoprotein

scientific article (publication date: March 2008)

Structure-based design of hepatitis C virus E2 glycoprotein improves serum binding and cross-neutralization

scientific article published on 17 April 2020

Structure-based design of hepatitis C virus E2 glycoprotein improves serum binding and cross-neutralization

scientific article published on 02 September 2020

The B-cell receptor of a hepatitis C virus (HCV)–associated non-Hodgkin lymphoma binds the viral E2 envelope protein, implicating HCV in lymphomagenesis ⬇️

scientific article published on December 15, 2001

The GB viruses: a review and proposed classification of GBV-A, GBV-C (HGV), and GBV-D in genus Pegivirus within the family Flaviviridae

scientific article

The Neutralizing Activity of Anti-Hepatitis C Virus Antibodies Is Modulated by Specific Glycans on the E2 Envelope Protein

scientific article

The effects of starvation and refeeding on muscle protein synthesis and catabolism in the young rat

scientific article published on May 1, 1978

The hepatitis C virus E1 glycoprotein undergoes productive folding but accelerated degradation when expressed as an individual subunit in CHO cells

scientific article

Toward a Hepatitis C Virus Vaccine: the Structural Basis of Hepatitis C Virus Neutralization by AP33, a Broadly Neutralizing Antibody

scientific article

Transient activation of the PI3K-AKT pathway by hepatitis C virus to enhance viral entry

scientific article

Viral evasion and challenges of hepatitis C virus vaccine development

scientific article published on 19 September 2016

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