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List of works by Trevor Lawley

A modified R-type bacteriocin specifically targeting Clostridium difficile prevents colonization of mice without affecting gut microbiota diversity

scientific article published on 24 March 2015

Abundant and diverse clustered regularly interspaced short palindromic repeat spacers in Clostridium difficile strains and prophages target multiple phage types within this pathogen

scientific article

Adaptation of host transmission cycle during Clostridium difficile speciation

scientific article published on 12 August 2019

Analysis of TcdB Proteins within the Hypervirulent Clade 2 Reveals an Impact of RhoA Glucosylation on Clostridium difficile Proinflammatory Activities

scientific article published on 11 January 2016

Antibiotic treatment of clostridium difficile carrier mice triggers a supershedder state, spore-mediated transmission, and severe disease in immunocompromised hosts

scientific article published on 29 June 2009

As Clear as Mud? Determining the Diversity and Prevalence of Prophages in the Draft Genomes of Estuarine Isolates of Clostridium difficile

scientific article published on 27 May 2015

Bacteriotherapy for the treatment of intestinal dysbiosis caused by Clostridium difficile infection ⬇️

scientific article published on July 15, 2013

Behavior and target site selection of conjugative transposon Tn916 in two different strains of toxigenic Clostridium difficile

scientific article

Clostridium sordellii genome analysis reveals plasmid localized toxin genes encoded within pathogenicity loci

scientific article published on 16 May 2015

Comparative genome and phenotypic analysis of Clostridium difficile 027 strains provides insight into the evolution of a hypervirulent bacterium

scientific article

Comparative genomics of vancomycin-resistant Staphylococcus aureus strains and their positions within the clade most commonly associated with Methicillin-resistant S. aureus hospital-acquired infection in the United States

scientific article

Comparative whole genome sequence analysis of the carcinogenic bacterial model pathogen Helicobacter felis

scientific article

Complete Genome Sequence of Campylobacter fetus subsp. venerealis Biovar Intermedius, Isolated from the Prepuce of a Bull

scientific article published on August 2013

Culturing of 'unculturable' human microbiota reveals novel taxa and extensive sporulation.

scientific article published on 04 May 2016

Defining the Roles of TcdA and TcdB in Localized Gastrointestinal Disease, Systemic Organ Damage, and the Host Response during Clostridium difficile Infections

scientific article published on 2 June 2015

Distinct Commensals Induce Interleukin-1β via NLRP3 Inflammasome in Inflammatory Monocytes to Promote Intestinal Inflammation in Response to Injury

scientific article published on 7 April 2015

Distinct microbial and immune niches of the human colon

scientific article published on 17 February 2020

Emergence and global spread of epidemic healthcare-associated Clostridium difficile

scientific article published on 9 December 2012

Emergence of an outbreak-associated Clostridium difficile variant with increased virulence.

scientific article

Emerging insights on intestinal dysbiosis during bacterial infections

scientific article

Enhanced susceptibility to Citrobacter rodentium infection in microRNA-155-deficient mice

scientific article published on 21 December 2012

Epithelial IL-22RA1-mediated fucosylation promotes intestinal colonization resistance to an opportunistic pathogen

scientific article

Evaluation of PacBio sequencing for full-length bacterial 16S rRNA gene classification

scientific article

Evolutionary dynamics of Clostridium difficile over short and long time scales

scientific article published on 20 April 2010

Functional and mutational analysis of conjugative transfer region 2 (Tra2) from the IncHI1 plasmid R27

scientific article

Functional genomics reveals that Clostridium difficile Spo0A coordinates sporulation, virulence and metabolism

scientific article

Genome-Based Infection Tracking Reveals Dynamics of Clostridium difficile Transmission and Disease Recurrence

scientific article published on 18 December 2015

Genome-wide screen for Salmonella genes required for long-term systemic infection of the mouse

scientific article

Global analysis of the sporulation pathway of Clostridium difficile.

scientific article

Gut-educated IgA plasma cells defend the meningeal venous sinuses

scientific article published on 04 November 2020

HPMCD: the database of human microbial communities from metagenomic datasets and microbial reference genomes

scientific article published on 17 November 2015

High-throughput analysis of gene essentiality and sporulation in Clostridium difficile

scientific article published on 24 February 2015

Host transmission of Salmonella enterica serovar Typhimurium is controlled by virulence factors and indigenous intestinal microbiota

scientific article

Identification of gut microbial species linked with disease variability in a widely used mouse model of colitis

scientific article published on 01 April 2022

Intestinal colonization resistance

scientific article published on January 2013

Lymphoid-Tissue-Resident Commensal Bacteria Promote Members of the IL-10 Cytokine Family to Establish Mutualism

scientific article

Murine models to study Clostridium difficile infection and transmission

scientific article

Neutrophils recruited by IL-22 in peripheral tissues function as TRAIL-dependent antiviral effectors against MCMV.

scientific article published on April 2014

Pathogen Resistance Mediated by IL-22 Signaling at the Epithelial-Microbiota Interface

scientific article

Pathogens' exploitation of the intestinal food web.

scientific article published on December 2014

Proteomic and genomic characterization of highly infectious Clostridium difficile 630 spores

scientific article published on 19 June 2009

Proteomic identification of Axc, a novel beta-lactamase with carbapenemase activity in a meropenem-resistant clinical isolate of Achromobacter xylosoxidans.

scientific article

Questioning the fetal microbiome illustrates pitfalls of low-biomass microbial studies

scientific article published in 2023

SpoIVA and SipL are Clostridium difficile spore morphogenetic proteins

scientific journal article

Systematic discovery of probiotics

scientific article published on January 2015

Targeted restoration of the intestinal microbiota with a simple, defined bacteriotherapy resolves relapsing Clostridium difficile disease in mice

scientific article

The essential genomic landscape of the commensal Bifidobacterium breve UCC2003.

scientific article

Therapeutic modulation of intestinal dysbiosis

scientific article published on 24 September 2012

Variation in Taxonomic Composition of the Fecal Microbiota in an Inbred Mouse Strain across Individuals and Time

scientific article published on 13 November 2015

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