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List of works by Joseph C. Wu

1357. A Combination of Itraconazole and Amiodarone Is Highly Effective Against Trypanosoma cruzi Infection of Human Stem Cell-Derived Cardiomyocytes

18F-labeled bombesin analogs for targeting GRP receptor-expressing prostate cancer.

scientific article published on March 2006

A Comprehensive TALEN-Based Knockout Library for Generating Human-Induced Pluripotent Stem Cell-Based Models for Cardiovascular Diseases

scientific article

A Rapid, High-Quality, Cost-Effective, Comprehensive and Expandable Targeted Next-Generation Sequencing Assay for Inherited Heart Diseases.

scientific article

A Tension-Based Model Distinguishes Hypertrophic versus Dilated Cardiomyopathy

scientific article published on 20 April 2016

A computational model of induced pluripotent stem-cell derived cardiomyocytes for high throughput risk stratification of KCNQ1 genetic variants

scientific article published on 14 August 2020

A human pluripotent stem cell surface N-glycoproteome resource reveals markers, extracellular epitopes, and drug targets.

scientific article

A nonviral minicircle vector for deriving human iPS cells

scientific article published on 7 February 2010

A novel platform device for rodent echocardiography

scientific article published on 6 June 2007

A review of human pluripotent stem cell-derived cardiomyocytes for high-throughput drug discovery, cardiotoxicity screening, and publication standards

scientific article published on 15 November 2012

A transgenic tri-modality reporter mouse

scientific article

Abnormal calcium handling properties underlie familial hypertrophic cardiomyopathy pathology in patient-specific induced pluripotent stem cells

scientific article

Abstract 151: short hairpin RNA interference therapy for diabetic murine wound closure and hindlimb ischemia

scientific article published on 01 March 2014

Abstract 158: Identification of BMP-Responsive Long Noncoding RNAs in Pluripotent Cells

scientific article published in March 2014

Adult Stem Cell Therapy and Heart Failure, 2000 to 2016: A Systematic Review

scientific article published on 24 August 2016

Advances in cardiovascular molecular imaging for tracking stem cell therapy

scientific article published on 10 May 2010

Advances in nanotechnology for the management of coronary artery disease

scientific article published on 13 December 2012

Allogeneic Mesenchymal Stromal Cells Overexpressing Mutant Human Hypoxia-Inducible Factor 1-α (HIF1-α) in an Ovine Model of Acute Myocardial Infarction

scientific article published on 06 July 2016

Alloimmune Responses of Humanized Mice to Human Pluripotent Stem Cell Therapeutics

scientific article published on August 2017

Alternative approaches to generating cardiomyocytes are under development

scientific article published on 19 August 2016

American Journal of Nuclear Medicine and Molecular Imaging: Editorial Board (2011) e-Century Publishing Corporation ⬇️

scientific article published on August 3, 2011

An antibody against SSEA-5 glycan on human pluripotent stem cells enables removal of teratoma-forming cells

scientific article published on 14 August 2011

An extracellular matrix paradox in myocardial scar formation

scientific article published on 12 August 2020

An unusual cause of stroke from a left atrial mass.

scientific article

Anisotropic microfibrous scaffolds enhance the organization and function of cardiomyocytes derived from induced pluripotent stem cells.

scientific article published on 17 July 2017

Antioxidants improve early survival of cardiomyoblasts after transplantation to the myocardium

scientific article

Applications of genetically engineered human pluripotent stem cell reporters in cardiac stem cell biology

scientific article published on 24 March 2018

Assessment of the Radiation Effects of Cardiac CT Angiography Using Protein and Genetic Biomarkers

scientific article published on 15 July 2015

Atomic force mechanobiology of pluripotent stem cell-derived cardiomyocytes

scientific article (publication date: 2012)

Autologous iPSC-Based Vaccines Elicit Anti-tumor Responses In Vivo

scientific article

Bioacoustic-enabled patterning of human iPSC-derived cardiomyocytes into 3D cardiac tissue.

scientific article published on 28 March 2017

Bioluminescence reporter gene imaging characterize human embryonic stem cell-derived teratoma formation

scientific article

Bioluminescence reporter gene imaging of human embryonic stem cell survival, proliferation, and fate

scientific article published in January 2009

Bone marrow characteristics associated with changes in infarct size after STEMI: a biorepository evaluation from the CCTRN TIME trial.

scientific article

Brief Report: External Beam Radiation Therapy for the Treatment of Human Pluripotent Stem Cell-Derived Teratomas

scientific article

CCL2-mediated endothelial injury drives cardiac dysfunction in long COVID

scientific article published in 2024

CD44 antibody-targeted liposomal nanoparticles for molecular imaging and therapy of hepatocellular carcinoma.

scientific article

COCATS 4 Task Force 4: Training in Multimodality Imaging

scientific article

COVID-19 and cardiovascular disease: from basic mechanisms to clinical perspectives

scientific article published on 20 July 2020

Can radionuclide imaging predict future response to stem cell therapy?

scientific article published in May 2008

Cancer therapy-induced cardiomyopathy: can human induced pluripotent stem cell modelling help prevent it?

scientific article published on 25 January 2018

Cardiac Cell Cycle Activation as a Strategy to Improve iPSC-Derived Cardiomyocyte Therapy

scientific article published in January 2018

Cardiac differentiation of embryonic stem cells with point-source electrical stimulation

scientific article

Cardiac stem cell biology: glimpse of the past, present, and future.

scientific article published on January 2014

Cardiac subtype characterization using all-optical action potential imaging.

scientific article

Cardiac tissue slice transplantation as a model to assess tissue-engineered graft thickness, survival, and function

scientific article

Cardiovascular molecular imaging

scientific article published on 25 June 2007

Cardiovascular molecular imaging as a tool to study biology

scientific article published on 9 December 2013

Cardiovascular molecular imaging: focus on clinical translation

scientific article

Cell Type-Specific Chromatin Signatures Underline Regulatory DNA Elements in Human Induced Pluripotent Stem Cells and Somatic Cells

scientific article published on 13 October 2017

Challenging the complementarity of different metrics of left atrial function: insight from a cardiomyopathy-based study

scientific article published on 16 September 2016

Characterization of the molecular mechanisms underlying increased ischemic damage in the aldehyde dehydrogenase 2 genetic polymorphism using a human induced pluripotent stem cell model system

scientific article

Chemically Defined Culture and Cardiomyocyte Differentiation of Human Pluripotent Stem Cells

scientific article published on 6 October 2015

Chemically defined generation of human cardiomyocytes

scientific article

Clinical dilemmas in treating left ventricular thrombus

scientific article published on 17 October 2006

Clinical hurdles for the transplantation of cardiomyocytes derived from human embryonic stem cells: role of molecular imaging

scientific article published on 29 December 2006

Clinical trial in a dish using iPSCs shows lovastatin improves endothelial dysfunction and cellular cross-talk in LMNA cardiomyopathy

scientific article published on 01 July 2020

Clonal precursor of bone, cartilage, and hematopoietic niche stromal cells.

scientific article published on 15 July 2013

Combining hiPSCs and Human Genetics: Major Applications in Drug Development

scientific article published in August 2017

Comparable calcium handling of human iPSC-derived cardiomyocytes generated by multiple laboratories.

scientific article

Comparison of Magnetic Resonance Imaging and Serum Biomarkers for Detection of Human Pluripotent Stem Cell-Derived Teratomas

scientific article published on 7 January 2016

Comparison of Non-Coding RNAs in Exosomes and Functional Efficacy of Human Embryonic Stem Cell- versus Induced Pluripotent Stem Cell-Derived Cardiomyocytes.

scientific article

Comparison of Non-human Primate versus Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes for Treatment of Myocardial Infarction.

scientific article published on 26 January 2018

Comparison of different adult stem cell types for treatment of myocardial ischemia

scientific article published on September 2008

Comparison of gene-transfer efficiency in human embryonic stem cells

scientific article

Comparison of human induced pluripotent and embryonic stem cells: fraternal or identical twins?

scientific article

Comparison of imaging techniques for tracking cardiac stem cell therapy

scientific article published on December 2007

Comparison of optical bioluminescence reporter gene and superparamagnetic iron oxide MR contrast agent as cell markers for noninvasive imaging of cardiac cell transplantation

scientific article published on 25 November 2008

Comparison of reporter gene and iron particle labeling for tracking fate of human embryonic stem cells and differentiated endothelial cells in living subjects

scientific article published on 24 January 2008

Comparison of transplantation of adipose tissue- and bone marrow-derived mesenchymal stem cells in the infarcted heart

scientific article

Concise Review: Review and Perspective of Cell Dosage and Routes of Administration From Preclinical and Clinical Studies of Stem Cell Therapy for Heart Disease

scientific article

Construction and validation of nano gold tripods for molecular imaging of living subjects

scientific article

Contractile force generation by 3D hiPSC-derived cardiac tissues is enhanced by rapid establishment of cellular interconnection in matrix with muscle-mimicking stiffness

scientific article published on 30 March 2017

Correction of human phospholamban R14del mutation associated with cardiomyopathy using targeted nucleases and combination therapy

scientific article

Cortical bone-derived stem cells: a novel class of cells for myocardial protection

scientific article published on August 2013

Costimulation-adhesion blockade is superior to cyclosporine A and prednisone immunosuppressive therapy for preventing rejection of differentiated human embryonic stem cells following transplantation

scientific article published on November 2013

Cross talk of combined gene and cell therapy in ischemic heart disease: role of exosomal microRNA transfer

scientific article published on September 2014

Cross-Site Reliability of Human Induced Pluripotent Stem-Cell Derived Cardiomyocyte Based Safety Assays using Microelectrode Arrays: Results from a Blinded CiPA Pilot Study.

scientific article published on 27 April 2018

Current perspectives on imaging cardiac stem cell therapy

scientific article published on 15 April 2010

Current-Controlled Electrical Point-Source Stimulation of Embryonic Stem Cells

scientific article

DNA damage-associated biomarkers in studying individual sensitivity to low-dose radiation from cardiovascular imaging

scientific article published on 5 June 2016

Defective Signaling in the JAK-STAT Pathway Tracks with Chronic Inflammation and Cardiovascular Risk in Aging Humans

scientific article published on 12 October 2016

Derivation of human induced pluripotent stem cells for cardiovascular disease modeling

scientific article published on April 2011

Development of a scalable suspension culture for cardiac differentiation from human pluripotent stem cells

scientific article

Development of poly(β-amino ester)-based biodegradable nanoparticles for nonviral delivery of minicircle DNA.

scientific article

Differences in Osteogenic Differentiation of Adipose-Derived Stromal Cells from Murine, Canine, and Human Sources In Vitro and In Vivo ⬇️

scientific article published on August 1, 2011

Differentiation, survival, and function of embryonic stem cell derived endothelial cells for ischemic heart disease.

scientific article published on September 2007

Direct measurement of myocardial viability by manganese-enhanced MRI (MEMRI) tracks the regenerative effects by human pluripotent stem cell derived cardiomyocytes (hPCMs)

Disruption of mesoderm formation during cardiac differentiation due to developmental exposure to 13-cis-retinoic acid

scientific article published in Scientific Reports

Dissecting the molecular relationship among various cardiogenic progenitor cells

scientific article published on 5 March 2013

Dissecting the oncogenic and tumorigenic potential of differentiated human induced pluripotent stem cells and human embryonic stem cells

scientific article

Distilling complexity to advance cardiac tissue engineering

scientific article

Distinct roles of microRNA-1 and -499 in ventricular specification and functional maturation of human embryonic stem cell-derived cardiomyocytes

scientific article (publication date: 2011)

Double knockdown of prolyl hydroxylase and factor-inhibiting hypoxia-inducible factor with nonviral minicircle gene therapy enhances stem cell mobilization and angiogenesis after myocardial infarction

scientific article

Drug screening using a library of human induced pluripotent stem cell-derived cardiomyocytes reveals disease-specific patterns of cardiotoxicity

scientific article

Dynamic microRNA expression during the transition from right ventricular hypertrophy to failure

scientific article

Dynamic microRNA expression programs during cardiac differentiation of human embryonic stem cells: role for miR-499.

scientific article

Dyslipidaemia: In vivo genome editing of ANGPTL3: a therapy for atherosclerosis?

scientific article published on 5 April 2018

Early stem cell engraftment predicts late cardiac functional recovery: preclinical insights from molecular imaging

scientific article

Effect of human donor cell source on differentiation and function of cardiac induced pluripotent stem cells

scientific article

Effective delivery of stem cells using an extracellular matrix patch results in increased cell survival and proliferation and reduced scarring in skin wound healing

scientific article published on 16 November 2012

Effects of cell number on teratoma formation by human embryonic stem cells

scientific article

Effects of epigenetic modulation on reporter gene expression: implications for stem cell imaging.

scientific article published on 24 October 2005

Effects of intracoronary CD34+ stem cell transplantation in nonischemic dilated cardiomyopathy patients: 5-year follow-up.

scientific article

Effects of ionizing radiation on self-renewal and pluripotency of human embryonic stem cells.

scientific article

Effects of long-term culture on human embryonic stem cell aging.

scientific article

Efficient Genome Editing in Induced Pluripotent Stem Cells with Engineered Nucleases In Vitro

scientific article published in January 2017

Efficient gene delivery of primary human cells using peptide linked polyethylenimine polymer hybrid

scientific article published on 8 April 2011

Elastic properties of induced pluripotent stem cells

scientific article

Electrophysiologic Characterization of Calcium Handling in Human Induced Pluripotent Stem Cell-Derived Atrial Cardiomyocytes.

scientific article

Embryonic stem cell biology: insights from molecular imaging

scientific article published on January 2010

Embryonic stem cell-derived endothelial cells engraft into the ischemic hindlimb and restore perfusion

scientific article

Enabling consistency in pluripotent stem cell-derived products for research and development and clinical applications through material standards.

scientific article

Endothelial progenitor cells in cardiovascular disease and chronic inflammation: from biomarker to therapeutic agent

scientific article published on December 2011

Engineered heart tissues and induced pluripotent stem cells: Macro- and microstructures for disease modeling, drug screening, and translational studies

scientific article

Engraftment of embryonic stem cells and differentiated progeny by host conditioning with total lymphoid irradiation and regulatory T cells

scientific article published on March 2015

Enhanced Aβ(1-40) production in endothelial cells stimulated with fibrillar Aβ(1-42)

scientific article

Enhanced healing of diabetic wounds by topical administration of adipose tissue-derived stromal cells overexpressing stromal-derived factor-1: biodistribution and engraftment analysis by bioluminescent imaging

scientific article

Enhancement of human adipose-derived stromal cell angiogenesis through knockdown of a BMP-2 inhibitor

scientific article published on January 2012

Epigenetic Modulations of Induced Pluripotent Stem Cells: Novel Therapies and Disease Models

scientific article published on January 2012

Epigenetic Regulation of Phosphodiesterases 2A and 3A Underlies Compromised β-Adrenergic Signaling in an iPSC Model of Dilated Cardiomyopathy.

scientific article

Exosomes as potential alternatives to stem cell therapy in mediating cardiac regeneration

scientific article published on June 2015

Extracellular Matrix can Recover the Downregulation of Adhesion Molecules after Cell Detachment and Enhance Endothelial Cell Engraftment.

scientific article published on 3 June 2015

Feeder-free derivation of induced pluripotent stem cells from adult human adipose stem cells

scientific article published on 08 September 2009

Finding Expandable Induced Cardiovascular Progenitor Cells

scientific article published on June 2016

Finding the rhythm of sudden cardiac death: new opportunities using induced pluripotent stem cell-derived cardiomyocytes

scientific article

Functional and transcriptional characterization of human embryonic stem cell-derived endothelial cells for treatment of myocardial infarction

scientific article

Functional characterization and expression profiling of human induced pluripotent stem cell- and embryonic stem cell-derived endothelial cells.

scientific article

GDF-15 (Growth Differentiation Factor 15) Is Associated With Lack of Ventricular Recovery and Mortality After Transcatheter Aortic Valve Replacement.

scientific article published in December 2017

Gene correction in human embryonic and induced pluripotent stem cells: promises and challenges ahead

scientific article

Generation of adult human induced pluripotent stem cells using nonviral minicircle DNA vectors

scientific article published on 23 December 2010

Generation of human iPSCs from human peripheral blood mononuclear cells using non-integrative Sendai virus in chemically defined conditions.

scientific article published on January 2013

Genetic and Epigenetic Regulation of Human Cardiac Reprogramming and Differentiation in Regenerative Medicine

scientific article

Genetic modification of embryonic stem cells with VEGF enhances cell survival and improves cardiac function

scientific article published on January 2007

Genome Editing in Cardiovascular Biology

scientific article published in March 2017

Genome Editing of Induced Pluripotent Stem Cells to Decipher Cardiac Channelopathy Variant

Genome editing of human embryonic stem cells and induced pluripotent stem cells with zinc finger nucleases for cellular imaging.

scientific article

Genome editing of isogenic human induced pluripotent stem cells recapitulates long QT phenotype for drug testing

scientific article

Genome-Wide Temporal Profiling of Transcriptome and Open Chromatin of Early Cardiomyocyte Differentiation Derived From hiPSCs and hESCs

scientific article published on 29 June 2017

Global Overview of the Transnational Alliance for Regenerative Therapies in Cardiovascular Syndromes (TACTICS) Recommendations: A Comprehensive Series of Challenges and Priorities of Cardiovascular Regenerative Medicine

scientific article published in January 2018

Global epigenomic reconfiguration during mammalian brain development

scientific article (publication date: 9 August 2013)

Global position paper on cardiovascular regenerative medicine

article

Guidelines for translational research in heart failure

scientific article published on 21 January 2015

Hemodynamic forces regulate embryonic stem cell commitment to vascular progenitors

scientific article published on November 2008

Hepatocyte growth factor or vascular endothelial growth factor gene transfer maximizes mesenchymal stem cell-based myocardial salvage after acute myocardial infarction.

scientific article

High efficiency differentiation of human pluripotent stem cells to cardiomyocytes and characterization by flow cytometry

scientific article published on 23 September 2014

High-throughput screening of tyrosine kinase inhibitor cardiotoxicity with human induced pluripotent stem cells.

scientific article

Human Engineered Heart Muscles Engraft and Survive Long Term in a Rodent Myocardial Infarction Model

scientific article published on 19 August 2015

Human Induced Pluripotent Stem Cell (hiPSC)-Derived Cells to Assess Drug Cardiotoxicity: Opportunities and Problems

scientific article published on 6 October 2017

Human Induced Pluripotent Stem Cells as a Platform for Personalized and Precision Cardiovascular Medicine.

scientific article published on July 2016

Human cardiac progenitor cells engineered with Pim-I kinase enhance myocardial repair.

scientific article

Human embryonic stem cell-derived endothelial cells as cellular delivery vehicles for treatment of metastatic breast cancer.

scientific article

Human germ cell differentiation from fetal- and adult-derived induced pluripotent stem cells

scientific article

Human iPS cell-based therapy: considerations before clinical applications

scientific article published on 02 March 2010

Human induced pluripotent stem cell (hiPSC) derived cardiomyocytes to understand and test cardiac calcium handling: A glass half full

scientific article published on 01 December 2015

Human induced pluripotent stem cell-derived cardiomyocytes as an in vitro model for coxsackievirus B3-induced myocarditis and antiviral drug screening platform

scientific article

Human neural stem cell grafts modify microglial response and enhance axonal sprouting in neonatal hypoxic-ischemic brain injury.

scientific article

Human stem cells for modeling heart disease and for drug discovery

scientific article

Human-induced pluripotent stem cell approaches to model inborn and acquired metabolic heart diseases

scientific article published on 26 March 2016

Human-induced pluripotent stem cell models of inherited cardiomyopathies

scientific article

Hurdles to clinical translation of human induced pluripotent stem cells

scientific article

Identification of a new modulator of the intercalated disc in a zebrafish model of arrhythmogenic cardiomyopathy.

scientific article published on June 2014

Image-guided cardiac cell delivery using high-resolution small-animal ultrasound

scientific article published on 18 August 2005

Imaging atherosclerosis with F18-fluorodeoxyglucose positron emission tomography: What are we actually seeing?

scientific article published on 01 August 2011

Imaging cardiac stem cell therapy: translations to human clinical studies

scientific article published on 03 May 2011

Imaging cardiac stem cell transplantation using radionuclide labeling techniques: clinical applications and future directions.

scientific article published on October 2013

Imaging chemically modified adenovirus for targeting tumors expressing integrin alphavbeta3 in living mice with mutant herpes simplex virus type 1 thymidine kinase PET reporter gene.

scientific article

Imaging gene expression in human mesenchymal stem cells: from small to large animals

scientific article published on 14 April 2009

Imaging neural stem cell graft-induced structural repair in stroke

scientific article published in January 2013

Imaging of STAT3 signaling pathway during mouse embryonic stem cell differentiation

scientific article

Imaging of VEGF receptor in a rat myocardial infarction model using PET

scientific article

Imaging of embryonic stem cell migration in vivo

scientific article published on January 2011

Imaging stem cell therapy for the treatment of peripheral arterial disease

scientific article published in May 2012

Imaging survival and function of transplanted cardiac resident stem cells

scientific article

Immunogenicity of pluripotent stem cells and their derivatives

scientific article published on February 2013

Immunologic Network and Response to Intramyocardial CD34+ Stem Cell Therapy in Patients With Dilated Cardiomyopathy.

scientific article published on 8 April 2015

Immunosuppressive therapy mitigates immunological rejection of human embryonic stem cell xenografts

scholarly article

Improved approach for chondrogenic differentiation of human induced pluripotent stem cells

scientific article published on April 2015

Improving the engraftment and integration of cell transplantation for cardiac regeneration

scientific article published on 01 March 2020

In Vivo Molecular Imaging of Murine Embryonic Stem Cells Delivered to a Burn Wound Surface via Integra® Scaffolding ⬇️

scientific article published on March 1, 2012

In vitro and in vivo bioluminescence reporter gene imaging of human embryonic stem cells

scientific article published on 02 May 2008

In vivo bioluminescence for tracking cell fate and function

scientific article

In vivo bioluminescence imaging of cord blood derived mesenchymal stem cell transplantation into rat myocardium

scientific article published on April 2006

In vivo directed differentiation of pluripotent stem cells for skeletal regeneration.

scientific article

In vivo functional and transcriptional profiling of bone marrow stem cells after transplantation into ischemic myocardium

scientific article published on 27 October 2011

In vivo imaging and evaluation of different biomatrices for improvement of stem cell survival

scientific article published on November 2007

In vivo imaging of embryonic stem cells reveals patterns of survival and immune rejection following transplantation

scientific article published in December 2008

In vivo multi-modality tracking of the regenerative effects of the human induced pluripotent stem cell-derived cardiomyocytes (iCMs).

scientific article published on 3 February 2015

In vivo visualization of embryonic stem cell survival, proliferation, and migration after cardiac delivery

scientific article

In vivo, ex vivo, and in vitro studies on apelin's effect on myocardial glucose uptake ⬇️

scientific article published on August 10, 2012

Increased Pyruvate Dehydrogenase Kinase 4 Expression in Lung Pericytes Is Associated with Reduced Endothelial-Pericyte Interactions and Small Vessel Loss in Pulmonary Arterial Hypertension.

scientific article published on 22 July 2016

Incremental value of right heart metrics and exercise performance to well-validated risk scores in dilated cardiomyopathy

scientific article

Induced Pluripotent Stem Cell Model of Pulmonary Arterial Hypertension Reveals Novel Gene Expression and Patient Specificity

scientific article published on 25 October 2016

Induced Pluripotent Stem Cells as a Platform to Understand Patient-Specific Responses to Opioids and Anaesthetics

scientific article published on 07 August 2020

Induced pluripotency of human prostatic epithelial cells.

scientific article

Induced pluripotent stem cell technology: a decade of progress

scientific article published on 16 December 2016

Induced pluripotent stem cell-derived cardiomyocytes for cardiovascular disease modeling and drug screening

scientific article

Induced pluripotent stem cells

scientific article published in April 2015

Induced pluripotent stem cells as a biopharmaceutical factory for extracellular vesicles

scientific article published on 13 March 2018

Induced pluripotent stem cells as a disease modeling and drug screening platform

scientific article

Induced pluripotent stem cells: at the heart of cardiovascular precision medicine

scientific article published on 24 March 2016

Inducible expression of stem cell associated intermediate filament nestin reveals an important role in glioblastoma carcinogenesis

scientific article published on 28 July 2010

Integration of genomics, proteomics, and imaging for cardiac stem cell therapy

scientific article published on June 2007

Intracellular and extracellular targets of molecular imaging in the myocardium

scientific article published on August 2008

Intracoronary transplantation of CD34(+) cells is associated with improved myocardial perfusion in patients with nonischemic dilated cardiomyopathy.

scientific article published on 18 November 2014

Large Animal Models of Ischemic Cardiomyopathy: Are They Enough to Bridge the Translational Gap?

scientific article published on 01 August 2015

Large animal induced pluripotent stem cells as pre-clinical models for studying human disease

scientific article published on June 2012

Lift NIH restrictions on chimera research.

scientific article

Limitations of dobutamine for enhancing flow heterogeneity in the presence of single coronary stenosis: implications for technetium-99m-sestamibi imaging ⬇️

scientific article published on March 1, 1998

Long term non-invasive imaging of embryonic stem cells using reporter genes

scientific article published on 23 July 2009

Loss of CDKN2B promotes p53-dependent smooth muscle cell apoptosis and aneurysm formation

scientific article

Magnetic Resonance Imaging of Cardiac Strain Pattern Following Transplantation of Human Tissue Engineered Heart Muscles.

scientific article

Magnetic resonance imaging of progressive cardiomyopathic changes in the db/db mouse

scientific article published on 22 November 2006

Manganese-Enhanced cardiac MRI (MEMRI) tracks long-term in vivo survival and restorative benefit of transplanted human Amnion-Derived Mesenchymal Stem Cells (hAMSC) after porcine ischemia-reperfusion injury

Manganese-enhanced MRI enables longitudinal tracking of transplanted stem cell viability in the murine myocardium.

scientific article

Matrigel Mattress: A Method for the Generation of Single Contracting Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes.

scientific article

Methods to assess stem cell lineage, fate and function

scientific article

Micro-CT for characterization of murine CV disease models

scientific article

Micro-positron emission tomography imaging of cardiac gene expression in rats using bicistronic adenoviral vector-mediated gene delivery

scientific article published on 8 March 2004

MicroRNA expression profiling of human-induced pluripotent and embryonic stem cells

scientific article published on January 2013

MicroRNA profiling of human-induced pluripotent stem cells

scientific article published on June 2009

MicroRNA-210 as a novel therapy for treatment of ischemic heart disease

scientific article

MicroRNA-302 increases reprogramming efficiency via repression of NR2F2.

scientific article

MicroRNA-mediated regulation of differentiation and trans-differentiation in stem cells

scientific article

Microfluidic Single-Cell Analysis of Transplanted Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes After Acute Myocardial Infarction

scientific article published on August 2015

Microfluidic single-cell analysis shows that porcine induced pluripotent stem cell-derived endothelial cells improve myocardial function by paracrine activation

scientific article

Microfluidic single-cell real-time PCR for comparative analysis of gene expression patterns

scientific article published on 5 April 2012

Mining Exosomal MicroRNAs from Human-Induced Pluripotent Stem Cells-Derived Cardiomyocytes for Cardiac Regeneration.

scientific article published in January 2018

Modeling Cardiovascular Diseases with Patient-Specific Human Pluripotent Stem Cell-Derived Cardiomyocytes

scientific article published on 18 February 2015

Modeling conduction in host-graft interactions between stem cell grafts and cardiomyocytes

scientific article

Modeling human diseases with induced pluripotent stem cells: from 2D to 3D and beyond

scientific article published on 8 March 2018

Molecular and functional resemblance of differentiated cells derived from isogenic human iPSCs and SCNT-derived ESCs

scientific article published on 4 December 2017

Molecular and magnetic resonance imaging of human embryonic stem cell-derived neural stem cell grafts in ischemic rat brain.

scientific article

Molecular imaging of RNA interference therapy targeting PHD2 for treatment of myocardial ischemia

scientific article

Molecular imaging of bone marrow mononuclear cell homing and engraftment in ischemic myocardium

scientific article published on 12 July 2007

Molecular imaging of cardiac cell transplantation in living animals using optical bioluminescence and positron emission tomography

scientific article

Molecular imaging of cardiac stem cell transplantation

scientific article

Molecular imaging of cardiovascular gene products

scientific article published in July 2004

Molecular imaging of embryonic stem cell misbehavior and suicide gene ablation.

scientific article published in January 2007

Molecular imaging of human embryonic stem cells.

scientific article published in January 2009

Molecular imaging of human embryonic stem cells: keeping an eye on differentiation, tumorigenicity and immunogenicity

scientific article published in December 2006

Molecular imaging of stem cells: tracking survival, biodistribution, tumorigenicity, and immunogenicity

scientific article published on April 2012

Molecular imaging of the kinetics of vascular endothelial growth factor gene expression in ischemic myocardium

scientific article

Molecular imaging: antidote to cardiac stem cell controversy

scientific article

Molecular imaging: the key to advancing cardiac stem cell therapy

scientific article published on 03 April 2013

Multimodal evaluation of in vivo magnetic resonance imaging of myocardial restoration by mouse embryonic stem cells.

scientific article

Multimodality imaging evaluation of functional and clinical benefits of percutaneous coronary intervention in patients with chronic total occlusion lesion

scientific article

Multiscale technologies for treatment of ischemic cardiomyopathy

scientific article published in September 2017

Myocardial perfusion imaging: Lessons learned and work to be done-update.

scientific article

Non-invasive bioluminescence imaging of myoblast-mediated hypoxia-inducible factor-1 alpha gene transfer

scientific article published on December 2011

Non-invasive indices of right ventricular function are markers of ventricular-arterial coupling rather than ventricular contractility: insights from a porcine model of chronic pressure overload.

scientific article published on 15 May 2013

Nonintegrating knockdown and customized scaffold design enhances human adipose-derived stem cells in skeletal repair.

scientific article

Noninvasive de novo imaging of human embryonic stem cell-derived teratoma formation

scientific article

Noninvasive evaluation of immunosuppressive drug efficacy on acute donor cell survival

scientific article published on May 2006

Noninvasive imaging of hypoxia-inducible factor-1α gene therapy for myocardial ischemia

scientific article published on October 2013

Noninvasive radionuclide imaging of cardiac gene therapy: progress and potential

scientific article published on August 2008

Novel codon-optimized mini-intronic plasmid for efficient, inexpensive, and xeno-free induction of pluripotency.

scientific article

Novel microRNA prosurvival cocktail for improving engraftment and function of cardiac progenitor cell transplantation

scientific article

Novel minicircle vector for gene therapy in murine myocardial infarction ⬇️

scientific article

Omics, Big Data, and Precision Medicine in Cardiovascular Sciences

scientific article published on 01 April 2018

Optical imaging of cardiac reporter gene expression in living rats

scientific article

Overview of High Throughput Sequencing Technologies to Elucidate Molecular Pathways in Cardiovascular Diseases ⬇️

scientific article published on June 7, 2013

Overview of stem cells and imaging modalities for cardiovascular diseases

scientific article published on July 2006

Partial Reprogramming of Pluripotent Stem Cell-Derived Cardiomyocytes into Neurons.

scientific article

Passive Stretch Induces Structural and Functional Maturation of Engineered Heart Muscle as Predicted by Computational Modeling.

scientific article published on 31 October 2017

Patient-Specific Induced Pluripotent Stem Cell-Based Disease Model for Pathogenesis Studies and Clinical Pharmacotherapy.

scientific article published in June 2017

Patient-Specific and Genome-Edited Induced Pluripotent Stem Cell-Derived Cardiomyocytes Elucidate Single-Cell Phenotype of Brugada Syndrome.

scientific article

Patient-Specific iPSC-Derived Endothelial Cells Uncover Pathways that Protect against Pulmonary Hypertension in BMPR2 Mutation Carriers

scientific article published on 02 December 2016

Patient-specific induced pluripotent stem cells as a model for familial dilated cardiomyopathy.

scientific article

Patient-specific stem cells and cardiovascular drug discovery

scientific article published on November 2013

Persistent donor cell gene expression among human induced pluripotent stem cells contributes to differences with human embryonic stem cells

scientific article

Pluripotent Stem Cell-Derived Cardiomyocytes as a Platform for Cell Therapy Applications: Progress and Hurdles for Clinical Translation

scientific article published on 6 March 2018

Pluripotent Stem Cells: Immune to the Immune System? ⬇️

scientific article published on December 12, 2012

Poor functional recovery after transplantation of diabetic bone marrow stem cells in ischemic myocardium

scientific article

Positron emission tomography imaging of cardiac reporter gene expression in living rats

scientific article

Positron emission tomography imaging of conditional gene activation in the heart.

scientific article published on 24 March 2007

Positron-emission tomography reporter gene expression imaging in rat myocardium

scientific article

Potential Strategies to Address the Major Clinical Barriers Facing Stem Cell Regenerative Therapy for Cardiovascular Disease: A Review

scientific article published on 31 August 2016

Pravastatin reverses obesity-induced dysfunction of induced pluripotent stem cell-derived endothelial cells via a nitric oxide-dependent mechanism

scientific article

Preclinical derivation and imaging of autologously transplanted canine induced pluripotent stem cells

scientific article published on 30 June 2011

Predicting the future with stem cells

scientific article

Pretreatment with angiotensin-converting enzyme inhibitor improves doxorubicin-induced cardiomyopathy via preservation of mitochondrial function

scientific article

Production of de novo cardiomyocytes: human pluripotent stem cell differentiation and direct reprogramming

scientific article

Prolonged survival of transplanted stem cells after ischaemic injury via the slow release of pro-survival peptides from a collagen matrix

scientific article published on 06 February 2018

Proteomic analysis of reporter genes for molecular imaging of transplanted embryonic stem cells

scientific article published on December 2006

Pushing the reset button: chemical-induced conversion of amniotic fluid stem cells into a pluripotent state

scientific article

Quantum dot imaging for embryonic stem cells

scientific article

RNA Sequencing Analysis Detection of a Novel Pathway of Endothelial Dysfunction in Pulmonary Arterial Hypertension.

scientific article

Radiation exposure from imaging tests: is there an increased cancer risk? ⬇️

scientific article published on February 1, 2011

Radiolabeled Duramycin: Promising Translational Imaging of Myocardial Apoptosis.

scientific article published on 9 February 2018

Rapid and efficient conversion of integration-free human induced pluripotent stem cells to GMP-grade culture conditions

scientific article (publication date: 2014)

Relationship between echocardiographic and magnetic resonance derived measures of right ventricular size and function in patients with pulmonary hypertension

scientific article

Reporter gene imaging following percutaneous delivery in swine moving toward clinical applications

scientific article

Reprogramming and transdifferentiation for cardiovascular development and regenerative medicine: where do we stand?

scientific article

Response to letter regarding article, "Cross talk of combined gene and cell therapy in ischemic heart disease: role of exosomal microRNA transfer"

scientific article published on 01 March 2015

Returns of the living dead: therapeutic action of irradiated and mitotically inactivated embryonic stem cells

scientific article published in October 2012

Right Heart Score for Predicting Outcome in Idiopathic, Familial, or Drug- and Toxin-Associated Pulmonary Arterial Hypertension

scientific article published on 14 May 2015

Right coronary cameral fistula resulting from surgery of double chamber right ventricle

scientific article published in September 2006

Role of molecular imaging in stem cell therapy for myocardial restoration

scientific article published on August 2010

Rosiglitazone increases myocardial glucose metabolism in insulin-resistant cardiomyopathy

scientific article published on March 2010

SETD7 Drives Cardiac Lineage Commitment through Stage-Specific Transcriptional Activation

scientific article published in March 2018

Sacrificial layer technique for axial force post assay of immature cardiomyocytes

scientific article published on February 2013

Safe genetic modification of cardiac stem cells using a site-specific integration technique

scientific article

Sex differences in the diagnostic evaluation of coronary artery disease

scientific article published on February 2011

Short Hairpin RNA Silencing of PHD-2 Improves Neovascularization and Functional Outcomes in Diabetic Wounds and Ischemic Limbs

scientific article

Short hairpin RNA interference therapy for ischemic heart disease

scientific article published on September 2008

Short-term immunosuppression promotes engraftment of embryonic and induced pluripotent stem cells

scientific article

Single cell transcriptional profiling reveals heterogeneity of human induced pluripotent stem cells

scientific article

Single-cell RNA sequencing in cardiovascular development, disease and medicine

scientific article published on 30 March 2020

Site-specific recombinase strategy to create induced pluripotent stem cells efficiently with plasmid DNA.

scientific article published on November 2011

Spatial and temporal kinetics of teratoma formation from murine embryonic stem cell transplantation

scientific article

Specific Imaging of Bacterial Infection using 6'' -(18)F-Fluoromaltotriose: A Second Generation PET Tracer Targeting the Maltodextrin Transporter in Bacteria

scientific article published on 10 May 2017

Stage-specific Effects of Bioactive Lipids on Human iPSC Cardiac Differentiation and Cardiomyocyte Proliferation.

scientific article published on 26 April 2018

Stem cell isolation: Differential stickiness

scientific article published in June 2013

Stem cell reprogramming: A 3D boost

scientific article published in February 2016

Stem cells and cardiovascular drug development--reply

scientific article

Strategies for Improving the Maturity of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes

scientific article published on 01 August 2018

Studies in adipose-derived stromal cells: migration and participation in repair of cranial injury after systemic injection.

scientific article published on March 2011

Surgically palliated double-inlet left ventricle with transposition of the great arteries mistaken for aortic aneurysm with dissection

scientific article published on 08 August 2007

Systematic Characterization of Long Noncoding RNAs Reveals the Contrasting Coordination of Cis- and Trans-Molecular Regulation in Human Fetal and Adult Hearts.

scientific article published on 19 February 2016

Telomere shortening and metabolic compromise underlie dystrophic cardiomyopathy

scientific article (publication date: 15 November 2016)

Telomere shortening is a hallmark of genetic cardiomyopathies

article published in the Proceedings of the National Academy of Sciences of the United States of America

Teratoma formation: a tool for monitoring pluripotency in stem cell research

scientific article

The Right Heart in Congenital Heart Disease, Mechanisms and Recent Advances ⬇️

scientific article published on June 15, 2012

The effects of levosimendan on renal function early after heart transplantation: results from a pilot randomized trial

scientific article published on 14 August 2014

The manipulation of natural killer cells to target tumor sites using magnetic nanoparticles

scientific article published on 8 May 2012

The presence of electromechanical mismatch in nonischemic dilated cardiomyopathy is associated with ventricular repolarization instability.

scientific article published on 25 November 2014

The role of Hath6, a newly identified shear-stress-responsive transcription factor, in endothelial cell differentiation and function

scientific article

The role of SIRT6 protein in aging and reprogramming of human induced pluripotent stem cells

scientific article

The use of human mesenchymal stem cells encapsulated in RGD modified alginate microspheres in the repair of myocardial infarction in the rat.

scientific article published on 20 June 2010

Time-dependent evolution of functional vs. remodeling signaling in induced pluripotent stem cell-derived cardiomyocytes and induced maturation with biomechanical stimulation

scientific article published on 16 December 2015

Timing of bone marrow cell delivery has minimal effects on cell viability and cardiac recovery after myocardial infarction

scientific article

Towards Cardio-Precision medicine

scientific article published in April 2017

Tracking gene and cell fate for therapeutic gain

scientific article published on February 2014

Trafficking mesenchymal stem cell engraftment and differentiation in tumor-bearing mice by bioluminescence imaging

scientific article

Transcriptional and functional profiling of human embryonic stem cell-derived cardiomyocytes

scientific article (publication date: 2008)

Transcriptional profiling of reporter genes used for molecular imaging of embryonic stem cell transplantation

scientific article published on 3 January 2006

Transcriptome Profiling of Patient-Specific Human iPSC-Cardiomyocytes Predicts Individual Drug Safety and Efficacy Responses In Vitro

scientific article

Transcriptome alteration in the diabetic heart by rosiglitazone: implications for cardiovascular mortality

scientific article

Transient, inducible, placenta-specific gene expression in mice

scientific article

Translation of Human-Induced Pluripotent Stem Cells: From Clinical Trial in a Dish to Precision Medicine

scientific article

Transplantation of human embryonic stem cell-derived endothelial cells for vascular diseases.

scientific article published on February 2009

Transplanted terminally differentiated induced pluripotent stem cells are accepted by immune mechanisms similar to self-tolerance

scientific article

Tumor-Promoting Effects of Myeloid-Derived Suppressor Cells Are Potentiated by Hypoxia-Induced Expression of miR-210.

scientific article published on 23 July 2015

Tumorigenicity as a clinical hurdle for pluripotent stem cell therapies

scientific article published on 06 August 2013

Tumorigenicity of pluripotent stem cells: biological insights from molecular imaging

scientific article published on 29 September 2010

Type 2 Diabetes Modifies the Association of CAD Genomic Risk Variants With Subclinical Atherosclerosis

scientific article published in December 2023

Universal intracellular biomolecule delivery with precise dosage control

scientific article published on 31 October 2018

Using Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes as a Model to Study Trypanosoma cruzi Infection.

scientific article

VEGF-C and aortic cardiomyocytes guide coronary artery stem development

scientific article

Variable activation of the DNA damage response pathways in patients undergoing single-photon emission computed tomography myocardial perfusion imaging

scientific article

[Molecular imaging for stem cell myocardial regeneration]

scientific article published on 01 November 2008

[Pyr1]-Apelin-13 delivery via nano-liposomal encapsulation attenuates pressure overload-induced cardiac dysfunction.

scientific article published on 13 October 2014

iPSC-derived cardiomyocytes reveal abnormal TGF-β signalling in left ventricular non-compaction cardiomyopathy.

scientific article published on 19 September 2016

mTORC1 and mTORC2 Play Different Roles in the Functional Survival of Transplanted Adipose-Derived Stromal Cells in Hind Limb Ischemic Mice Via Regulating Inflammation In Vivo ⬇️

scientific article published on January 1, 2013

nAChRs mediate human embryonic stem cell-derived endothelial cells: proliferation, apoptosis, and angiogenesis

scientific article

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