Search filters

List of works by Sam M Janes

A comparison of tracheal scaffold strategies for pediatric transplantation in a rabbit model

scientific article published on 4 August 2017

A general mechanism for intracellular toxicity of metal-containing nanoparticles.

scientific article

Airway Basal Cell Heterogeneity and Lung Squamous Cell Carcinoma.

scientific article

Airway and alveolar epithelial cells in culture

scientific article published on 07 November 2019

Airway stem cells and lung cancer.

scientific article

Airway tissue engineering for congenital laryngotracheal disease

scientific article published on 22 February 2016

Antitumor effects of TRAIL-expressing mesenchymal stromal cells in a mouse xenograft model of human mesothelioma

scientific article published on 19 December 2014

Attitudes towards lung cancer screening in socioeconomically deprived and heavy smoking communities: informing screening communication

scientific article published on 11 July 2016

Autologous Cell Seeding in Tracheal Tissue Engineering.

scientific article published on 26 October 2017

BARD1 serum autoantibodies for the detection of lung cancer.

scientific article

BRCA1/MAD2L1 deficiency disrupts the spindle assembly checkpoint to confer vinorelbine resistance in mesothelioma

scientific article published on 06 November 2020

Bioengineered airway epithelial grafts with mucociliary function based on collagen IV- and laminin-containing extracellular matrix scaffolds

scientific article published on 22 May 2020

Bone marrow stem cells expressing keratinocyte growth factor via an inducible lentivirus protects against bleomycin-induced pulmonary fibrosis

scientific article

CADM1 inhibits squamous cell carcinoma progression by reducing STAT3 activity.

scientific article

Cell migration leads to spatially distinct but clonally related airway cancer precursors.

scientific article published on 18 February 2014

Cell-intrinsic differences between human airway epithelial cells from children and adults

scientific article published on 20 April 2020

Characterizing smoking-induced transcriptional heterogeneity in the human bronchial epithelium at single-cell resolution

scientific article published on 11 December 2019

Children must be protected from the tobacco industry's marketing tactics.

scientific article published on 9 December 2013

Combination of endobronchial ultrasound‐guided transbronchial needle aspiration with standard bronchoscopic techniques for the diagnosis of stage I and stage II pulmonary sarcoidosis

scientific article published on April 1, 2011

Combined cell-gene therapy for lung cancer: rationale, challenges and prospects.

scientific article

Corrigendum: Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution

scientific article published in Nature

Cross-talk between human airway epithelial cells and 3T3-J2 feeder cells involves partial activation of human MET by murine HGF.

scientific article

Cryopreservation of human mesenchymal stromal cells expressing TRAIL for human anti-cancer therapy.

scientific article published on July 2016

Deciphering the genomic, epigenomic, and transcriptomic landscapes of pre-invasive lung cancer lesions

scientific article published on 21 January 2019

Defining the path: lung cancer CT screening in Europe.

scientific article published on 19 July 2017

Delivering low-dose CT screening for lung cancer: a pragmatic approach

scientific article published on 13 August 2020

Diagnostic accuracy of whole-body MRI versus standard imaging pathways for metastatic disease in newly diagnosed colorectal cancer: the prospective Streamline C trial.

scientific article published on 9 May 2019

Diagnostic accuracy of whole-body MRI versus standard imaging pathways for metastatic disease in newly diagnosed non-small-cell lung cancer: the prospective Streamline L trial

scientific article published on 09 May 2019

Emerging resistance pathways in lung cancer: what has ROS-1 taught us?

scientific article published in February 2018

Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration for the Diagnosis of Intrathoracic Lymphadenopathy in Patients with Extrathoracic Malignancy: A Multicenter Study

scientific article published on September 1, 2011

Endobronchial ultrasound-guided transbronchial needle aspiration for lymphoma: the final frontier

scientific article published on November 2013

Endobronchial ultrasound-guided transbronchial needle aspiration prevents mediastinoscopies in the diagnosis of isolated mediastinal lymphadenopathy: a prospective trial

scientific article

Engineered human mesenchymal stem cells for neuroblastoma therapeutics.

scientific article published on 8 May 2019

Epidermal stem cells

scientific article

Epithelial cell migration as a potential therapeutic target in early lung cancer

scientific article published on 31 January 2017

Evaluation of cardiovascular risk in a lung cancer screening cohort

scientific article published on 26 September 2019

Expansion of Human Airway Basal Stem Cells and Their Differentiation as 3D Tracheospheres.

scientific article

Genetically modified mesenchymal stromal cells in cancer therapy

scientific article

Genomic evidence of pre‐invasive clonal expansion, dispersal and progression in bronchial dysplasia

scientific article published on April 19, 2011

High prevalence of malignancy in HIV-positive patients with mediastinal lymphadenopathy: a study in the era of antiretroviral therapy

scientific article

Human SARS-CoV-2 challenge uncovers local and systemic response dynamics

scientific article published on 19 June 2024

Hyperthermia treatment of tumors by mesenchymal stem cell-delivered superparamagnetic iron oxide nanoparticles.

scientific article published on 9 May 2016

Immune surveillance in clinical regression of pre-invasive squamous cell lung cancer

scientific article published on 20 July 2020

Impact of EBUS-TBNA on modalities for tissue acquisition in patients with lung cancer

scientific article

Impact of a Lung Cancer Screening Information Film on Informed Decision-making: A Randomized Trial

scientific article published on 01 June 2019

Impact of radiographer immediate reporting of chest X-rays from general practice on the lung cancer pathway (radioX): study protocol for a randomised control trial.

scientific article published on 6 November 2017

In vivo implantation of a tissue engineered stem cell seeded hemi-laryngeal replacement maintains airway, phonation, and swallowing in pigs.

scientific article published on 19 October 2017

Integrated 18F-fluorodeoxyglucose-positron emission tomography/dynamic contrast-enhanced computed tomography to phenotype non-small cell lung carcinoma

scientific article

LRIG1 regulates cadherin-dependent contact inhibition directing epithelial homeostasis and pre-invasive squamous cell carcinoma development.

scientific article published on March 2013

Lessons on managing pulmonary nodules from NELSON: we have come a long way

scientific article published on 06 March 2019

Local and systemic responses to SARS-CoV-2 infection in children and adults

scientific article published on 22 December 2021

Long term radiological features of radiation-induced lung damage.

scientific article published on 27 November 2017

Loss of functional BAP1 augments sensitivity to TRAIL in cancer cells

scientific article published on 18 January 2018

Low-dose Computed Tomography Screening: The (Other) Lung Cancer Revolution

scientific article published on 27 August 2019

Lung Screen Uptake Trial (LSUT): Randomized Controlled Clinical Trial Testing Targeted Invitation Materials

scientific article published on 11 December 2019

Lung Screen Uptake Trial: results from a single lung cancer screening round

scientific article published on 05 August 2020

Lung cancer and lung stem cells: strange bedfellows?

scientific article published on 7 December 2006

Lung cancer diagnosis and staging with endobronchial ultrasound-guided transbronchial needle aspiration compared with conventional approaches: an open-label, pragmatic, randomised controlled trial.

scientific article

Lung cancer screening: improving understanding of the psychological impact.

scientific article published on 31 August 2016

Lung cancer screening: what we can learn from UKLS?

scientific article

Lung cancer: progress in diagnosis, staging and therapy.

scientific article

Macrophage migration inhibitory factor-CXCR4 is the dominant chemotactic axis in human mesenchymal stem cell recruitment to tumors.

scientific article

Massive pulmonary carcinoid tumor deemed inoperable until (68)Ga DOTATATE positron emission tomography/magnetic resonance imaging.

scientific article published in September 2014

Mediastinal staging of NSCLC with endoscopic and endobronchial ultrasound

scientific article

Membrane-spanning DNA nanopores with cytotoxic effect

scientific article published on 7 October 2014

Mesenchymal stem cell therapy for lung diseases: oasis or mirage?

scientific article published on 24 January 2013

Mesenchymal stem cells as vectors for lung cancer therapy

scientific article

Mesenchymal stem cells as vectors for lung disease

scientific article published on August 2008

Mesenchymal stromal cell delivery of full-length tumor necrosis factor-related apoptosis-inducing ligand is superior to soluble type for cancer therapy.

scientific article

Mobile DNA in cancer. Extensive transduction of nonrepetitive DNA mediated by L1 retrotransposition in cancer genomes

scientific article

Monitoring neovascularization and integration of decellularized human scaffolds using photoacoustic imaging

scientific article published on 08 January 2019

Myd88 deficiency influences murine tracheal epithelial metaplasia and submucosal gland abundance

scientific article published on June 1, 2011

New roles for integrins in squamous-cell carcinoma

scientific article

Non-Invasive Longitudinal Bioluminescence Imaging of Human Mesoangioblasts in Bioengineered Esophagi

scientific article published on 01 February 2019

Non-small-cell lung cancer resectability: diagnostic value of PET/MR.

scientific article

On the Origin of Lung Cancers

scientific article published on 01 March 2020

Optimized isolation and expansion of human airway epithelial basal cells from endobronchial biopsy samples

scientific article published on 10 May 2017

PI3-kinase-dependent activation of apoptotic machinery occurs on commitment of epidermal keratinocytes to terminal differentiation

scientific article published on March 2009

Patient experience and perceived acceptability of whole-body magnetic resonance imaging for staging colorectal and lung cancer compared with current staging scans: a qualitative study

scientific article published on 6 September 2017

Patient preferences for whole-body MRI or conventional staging pathways in lung and colorectal cancer: a discrete choice experiment

scientific article published on 01 April 2019

Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution

scientific article

Preinvasive disease of the airway.

scientific article

Primed infusion with delayed equilibrium of Gd.DTPA for enhanced imaging of small pulmonary metastases

scientific article

Psychological outcomes of low-dose CT lung cancer screening in a multisite demonstration screening pilot: the Lung Screen Uptake Trial (LSUT)

scientific article published on 21 October 2020

Pulmonary mass in a 19-year-old male. Inflammatory myofibroblastic tumour

scientific article

Pulmonary nodules and CT screening: the past, present and future

scientific article

Rac1 deletion causes thymic atrophy

scientific article published on 29 April 2011

Rapid Expansion of Human Epithelial Stem Cells Suitable for Airway Tissue Engineering.

scientific article

Regenerating human epithelia with cultured stem cells: feeder cells, organoids and beyond.

scientific article

Reply to: "Recent Advances in Circumferential Tracheal Replacement and Transplantation".

scientific article published on 27 January 2016

Reply: Optimum performance of endobronchial ultrasound-guided transbronchial needle aspiration

scientific article published in November 2013

Retrospective response analysis of BAP1 expression to predict the clinical activity of systemic cytotoxic chemotherapy in mesothelioma

scientific article published on 05 December 2018

Review of the British Thoracic Society Winter Meeting 2013, 4-6 December, London, UK.

scientific article published on April 2014

Review of the British Thoracic Society Winter Meeting 2014, 3-5 December, London, UK.

scientific article published in March 2015

Review of the British Thoracic Society Winter Meeting 2015, 2-4 December, London, UK.

scientific article published on 25 March 2016

Sequential screening for lung cancer in a high-risk group: randomised controlled trial: LungSEARCH: a randomised controlled trial of Surveillance using sputum and imaging for the EARly detection of lung Cancer in a High-risk group

scientific article published on 17 October 2019

Sestrins induce natural killer function in senescent-like CD8+ T cells

scientific article published on 30 March 2020

Single-cell multi-omics analysis of the immune response in COVID-19

scientific article published on 20 April 2021

Smokers' interest in a lung cancer screening programme: a national survey in England.

scientific article published on 2 May 2018

Smoking is associated with pessimistic and avoidant beliefs about cancer: results from the International Cancer Benchmarking Partnership.

scientific article

Spatial and temporal diversity in genomic instability processes defines lung cancer evolution

scientific article

Stem Cell Implants for Cancer Therapy: TRAIL-Expressing Mesenchymal Stem Cells Target Cancer Cells In Situ

scientific article

Stem cells and pulmonary fibrosis: cause or cure?

scientific article published in July 2012

Stem cells for lung disease

scientific article published on July 2007

Stem cells of the alveolar epithelium

scientific article

Stochastic homeostasis in human airway epithelium is achieved by neutral competition of basal cell progenitors

scientific article published on 22 October 2013

Streamlining staging of lung and colorectal cancer with whole body MRI; study protocols for two multicentre, non-randomised, single-arm, prospective diagnostic accuracy studies (Streamline C and Streamline L)

scientific article

Suitability of endobronchial ultrasound-guided transbronchial needle aspiration specimens for subtyping and genotyping of non-small cell lung cancer: a multicenter study of 774 patients

scientific article

Surface modification of a POSS-nanocomposite material to enhance cellular integration of a synthetic bioscaffold.

scientific article published on 5 January 2016

Systemic but not topical TRAIL-expressing mesenchymal stem cells reduce tumour growth in malignant mesothelioma

scientific article

TRAIL delivery by MSC-derived extracellular vesicles is an effective anticancer therapy

scientific article

Targeting EGFR signalling in chronic lung disease: therapeutic challenges and opportunities

scientific article

The secret lives of cancer cell lines

Therapeutic potential of stem cells in lung disease: progress and pitfalls

scientific article published on January 2008

Thoracic Oncology HERMES syllabus: setting the basis for thoracic oncology training in Europe: Table 1–

scientific article published on 01 September 2013

Thoracic oncology HERMES: European curriculum recommendations for training in thoracic oncology.

scientific article published on September 2016

Tissue engineering airway mucosa: a systematic review

scientific article

Tissue-Engineered Tracheal Replacement in a Child: A 4-Year Follow-Up Study

scientific article published on 2 June 2015

Tracheal Replacement Therapy with a Stem Cell-Seeded Graft: Lessons from Compassionate Use Application of a GMP-Compliant Tissue-Engineered Medicine

scientific article published on June 2017

Tracking genomic cancer evolution for precision medicine: the lung TRACERx study

scientific article

Tracking the Evolution of Non-Small-Cell Lung Cancer

scientific article published on 26 April 2017

Transcriptional Profiling of Endobronchial Ultrasound-Guided Lymph Node Samples Aids Diagnosis of Mediastinal Lymphadenopathy

scientific article published on 13 August 2015

Transient activation of FOXN1 in keratinocytes induces a transcriptional programme that promotes terminal differentiation: contrasting roles of FOXN1 and Akt.

scientific article

Tumor heterogeneity and permeability as measured on the CT component of PET/CT predict survival in patients with non-small cell lung cancer.

scientific article published on 9 May 2013

Two phenotypes that predict prognosis in lung adenocarcinoma

scientific article published in 2022

Using a Three-Dimensional Collagen Matrix to Deliver Respiratory Progenitor Cells to Decellularized Trachea In Vivo

scientific article published on 01 February 2019

Utility of endobronchial ultrasound-guided transbronchial needle aspiration in patients with tuberculous intrathoracic lymphadenopathy: a multicentre study

scientific article

Vacuum-assisted decellularization: an accelerated protocol to generate tissue-engineered human tracheal scaffolds.

scientific article published on 05 February 2017

Whole-body MRI compared with standard pathways for staging metastatic disease in lung and colorectal cancer: the Streamline diagnostic accuracy studies

scientific article published on 01 December 2019

β-Catenin determines upper airway progenitor cell fate and preinvasive squamous lung cancer progression by modulating epithelial-mesenchymal transition

scientific article