List of works - Hyun Seung Ban

A Novel Malate Dehydrogenase 2 Inhibitor Suppresses Hypoxia-Inducible Factor-1 by Regulating Mitochondrial Respiration

scientific article

Allene as an alternative functional group for drug design: effect of C--C multiple bonds conjugated with quinazolines on the inhibition of EGFR tyrosine kinase.

scientific article

Bcl-2-dependent synthetic lethal interaction of the IDF-11774 with the V0 subunit C of vacuolar ATPase (ATP6V0C) in colorectal cancer

scientific article published on 13 November 2018

Biological evaluation of dopamine analogues containing phenylboronic acid group as new boron carriers.

scientific article published on 19 April 2011

Boron-Based Drug Design

scientific article published on 20 March 2015

Boron-containing phenoxyacetanilide derivatives as hypoxia-inducible factor (HIF)-1α inhibitors

scientific article published on 06 January 2010

DDIAS suppresses TRAIL-mediated apoptosis by inhibiting DISC formation and destabilizing caspase-8 in cancer cells.

scientific article published on 15 December 2017

DNA damage induced apoptosis suppressor (DDIAS) is upregulated via ERK5/MEF2B signaling and promotes β-catenin-mediated invasion

scientific article published on 10 July 2016

DNA damage-induced apoptosis suppressor (DDIAS), a novel target of NFATc1, is associated with cisplatin resistance in lung cancer

scientific article published on 19 October 2015

Data on the transcriptional regulation of DNA damage induced apoptosis suppressor (DDIAS) by ERK5/MEF2B pathway in lung cancer cells

scientific article

Design and synthesis of fluorescence-labeled closo-dodecaborate lipid: its liposome formation and in vivo imaging targeting of tumors for boronneutron capture therapy

scientific article published on 23 December 2011

Development of High Boron Content Liposomes and Their Promising Antitumor Effect for Neutron Capture Therapy of Cancers

article

Development of boron nanocapsules for neutron capture therapy.

scientific article published on 28 March 2009

Development of hypoxia-inducible factor (HIF)-1α inhibitors: effect of ortho-carborane substituents on HIF transcriptional activity under hypoxia.

scientific article published on 8 December 2012

Diaryl-substituted ortho-carboranes as a new class of hypoxia inducible factor-1α inhibitors.

scientific article published on April 2014

Discovery of (2-aminophenyl)methanol as a new molecular chaperone that rescues the localization of P123S mutant pendrin stably expressed in HEK293 cells

scientific article

Discovery of 1-[4-(N-benzylamino)phenyl]-3-phenylurea derivatives as non-peptidic selective SUMO-sentrin specific protease (SENP)1 inhibitors

scientific article published on 03 July 2012

Discovery of Indenopyrazoles as a New Class of Hypoxia Inducible Factor (HIF)-1 Inhibitors

scientific article published on 27 January 2013

Discovery of boron-conjugated 4-anilinoquinazoline as a prolonged inhibitor of EGFR tyrosine kinase.

scientific article published on 20 August 2009

Discovery of carboranes as inducers of 20S proteasome activity.

scientific article published on August 2010

Discovery of indenopyrazoles as EGFR and VEGFR-2 tyrosine kinase inhibitors by in silico high-throughput screening.

scientific article published on 30 October 2007

Dodecaborate lipid liposomes as new vehicles for boron delivery system of neutron capture therapy.

scientific article published on 27 March 2010

Effects of hyperin, isoquercitrin and quercetin on lipopolysaccharide-induced nitrite production in rat peritoneal macrophages.

scientific article published in November 2008

Epigenetic Alterations of Heat Shock Proteins (HSPs) in Cancer

scientific article published on 25 September 2019

Epigenetic Associations between lncRNA/circRNA and miRNA in Hepatocellular Carcinoma

scientific article published on 14 September 2020

High-Performance Conducting Polymer Nanotube-based Liquid-Ion Gated Field-Effect Transistor Aptasensor for Dopamine Exocytosis

scientific article published on 28 February 2020

Hypoxia-inducible factor (HIF) inhibitors: a patent survey (2011-2015).

scientific article published on 16 February 2016

Hypoxia-inducible factor inhibitors: a survey of recent patented compounds (2004 - 2010).

scientific article published on 06 January 2011

Identification of HSP60 as a Primary Target ofo-Carboranylphenoxyacetanilide, an HIF-1α Inhibitor

scientific article published on 01 September 2010

Identification of Targets of the HIF-1 Inhibitor IDF-11774 Using Alkyne-Conjugated Photoaffinity Probes.

scientific article published on 7 July 2016

Identification of malate dehydrogenase 2 as a target protein of the HIF-1 inhibitor LW6 using chemical probes.

scientific article published on 9 August 2013

Inhibition of prostaglandin E(2) production by taiwanin C isolated from the root of Acanthopanax chiisanensis and the mechanism of action

scientific article published in November 2002

Inhibition of prostaglandin E2 production by platycodin D isolated from the root of Platycodon grandiflorum.

scientific article published in June 2001

Inhibitory effects of furanocoumarins isolated from the roots of Angelica dahurica on prostaglandin E2 production.

scientific article

Lignans from Acanthopanax chiisanensis having an inhibitory activity on prostaglandin E2 production.

scientific article published in February 2005

Methyl 3-(3-(4-(2,4,4-Trimethylpentan-2-yl)phenoxy)-propanamido)benzoate as a Novel and Dual Malate Dehydrogenase (MDH) 1/2 Inhibitor Targeting Cancer Metabolism.

scientific article

NFATc1 regulates the transcription of DNA damage-induced apoptosis suppressor

scientific article

PI3K/AKT/β-Catenin Signaling Regulates Vestigial-Like 1 Which Predicts Poor Prognosis and Enhances Malignant Phenotype in Gastric Cancer

scientific article published on 03 December 2019

Properties of a glycogen like polysaccharide produced by a mutant of Escherichia coli lacking glycogen synthase and maltodextrin phosphorylase.

scientific article published on 30 September 2015

Stability of the cancer target DDIAS is regulated by the CHIP/HSP70 pathway in lung cancer cells

scientific article published on 12 January 2017

Suppression of HIF-1α accumulation by betulinic acid through proteasome activation in hypoxic cervical cancer

scientific article published on 14 January 2020

Synthesis and biological evaluation of benzamides and benzamidines as selective inhibitors of VEGFR tyrosine kinases

scientific article published on 08 August 2006

Synthesis and biological evaluation of kresoxim-methyl analogues as novel inhibitors of hypoxia-inducible factor (HIF)-1 accumulation in cancer cells.

scientific article published on 9 May 2017

Synthesis and structure-activity relationship study of chemical probes as hypoxia induced factor-1α/malate dehydrogenase 2 inhibitors.

scientific article

The Epigenetic Regulation of HCC Metastasis

scientific article published in 2018

The Roles of Hypoxia-Inducible Factors and Non-Coding RNAs in Gastrointestinal Cancer

scientific article published on 04 December 2019

The novel hypoxia-inducible factor-1α inhibitor IDF-11774 regulates cancer metabolism, thereby suppressing tumor growth.

scientific article published on June 2017

o-Carboranylalkoxy-1,3,5-Triazine Derivatives: Synthesis, Characterization, X-ray Structural Studies, and Biological Activity

scientific article published on 30 August 2018

p300 cooperates with c-Jun and PARP-1 at the p300 binding site to activate RhoB transcription in NSC126188-mediated apoptosis

scientific article published on 15 March 2014

List of works by Hyun Seung Ban

A Novel Malate Dehydrogenase 2 Inhibitor Suppresses Hypoxia-Inducible Factor-1 by Regulating Mitochondrial Respiration

Allene as an alternative functional group for drug design: effect of C--C multiple bonds conjugated with quinazolines on the inhibition of EGFR tyrosine kinase.

Bcl-2-dependent synthetic lethal interaction of the IDF-11774 with the V0 subunit C of vacuolar ATPase (ATP6V0C) in colorectal cancer

Biological evaluation of dopamine analogues containing phenylboronic acid group as new boron carriers.

Boron-Based Drug Design

Boron-containing phenoxyacetanilide derivatives as hypoxia-inducible factor (HIF)-1α inhibitors

DDIAS suppresses TRAIL-mediated apoptosis by inhibiting DISC formation and destabilizing caspase-8 in cancer cells.

DNA damage induced apoptosis suppressor (DDIAS) is upregulated via ERK5/MEF2B signaling and promotes β-catenin-mediated invasion

DNA damage-induced apoptosis suppressor (DDIAS), a novel target of NFATc1, is associated with cisplatin resistance in lung cancer

Data on the transcriptional regulation of DNA damage induced apoptosis suppressor (DDIAS) by ERK5/MEF2B pathway in lung cancer cells

Design and synthesis of fluorescence-labeled closo-dodecaborate lipid: its liposome formation and in vivo imaging targeting of tumors for boronneutron capture therapy

Development of High Boron Content Liposomes and Their Promising Antitumor Effect for Neutron Capture Therapy of Cancers

Development of boron nanocapsules for neutron capture therapy.

Development of hypoxia-inducible factor (HIF)-1α inhibitors: effect of ortho-carborane substituents on HIF transcriptional activity under hypoxia.

Diaryl-substituted ortho-carboranes as a new class of hypoxia inducible factor-1α inhibitors.

Discovery of (2-aminophenyl)methanol as a new molecular chaperone that rescues the localization of P123S mutant pendrin stably expressed in HEK293 cells

Discovery of 1-[4-(N-benzylamino)phenyl]-3-phenylurea derivatives as non-peptidic selective SUMO-sentrin specific protease (SENP)1 inhibitors

Discovery of Indenopyrazoles as a New Class of Hypoxia Inducible Factor (HIF)-1 Inhibitors

Discovery of boron-conjugated 4-anilinoquinazoline as a prolonged inhibitor of EGFR tyrosine kinase.

Discovery of carboranes as inducers of 20S proteasome activity.

Discovery of indenopyrazoles as EGFR and VEGFR-2 tyrosine kinase inhibitors by in silico high-throughput screening.

Dodecaborate lipid liposomes as new vehicles for boron delivery system of neutron capture therapy.

Effects of hyperin, isoquercitrin and quercetin on lipopolysaccharide-induced nitrite production in rat peritoneal macrophages.

Epigenetic Alterations of Heat Shock Proteins (HSPs) in Cancer

Epigenetic Associations between lncRNA/circRNA and miRNA in Hepatocellular Carcinoma

High-Performance Conducting Polymer Nanotube-based Liquid-Ion Gated Field-Effect Transistor Aptasensor for Dopamine Exocytosis

Hypoxia-inducible factor (HIF) inhibitors: a patent survey (2011-2015).

Hypoxia-inducible factor inhibitors: a survey of recent patented compounds (2004 - 2010).

Identification of HSP60 as a Primary Target ofo-Carboranylphenoxyacetanilide, an HIF-1α Inhibitor

Identification of Targets of the HIF-1 Inhibitor IDF-11774 Using Alkyne-Conjugated Photoaffinity Probes.

Identification of malate dehydrogenase 2 as a target protein of the HIF-1 inhibitor LW6 using chemical probes.

Inhibition of prostaglandin E(2) production by taiwanin C isolated from the root of Acanthopanax chiisanensis and the mechanism of action

Inhibition of prostaglandin E2 production by platycodin D isolated from the root of Platycodon grandiflorum.

Inhibitory effects of furanocoumarins isolated from the roots of Angelica dahurica on prostaglandin E2 production.

Lignans from Acanthopanax chiisanensis having an inhibitory activity on prostaglandin E2 production.

Methyl 3-(3-(4-(2,4,4-Trimethylpentan-2-yl)phenoxy)-propanamido)benzoate as a Novel and Dual Malate Dehydrogenase (MDH) 1/2 Inhibitor Targeting Cancer Metabolism.

NFATc1 regulates the transcription of DNA damage-induced apoptosis suppressor

PI3K/AKT/β-Catenin Signaling Regulates Vestigial-Like 1 Which Predicts Poor Prognosis and Enhances Malignant Phenotype in Gastric Cancer

Properties of a glycogen like polysaccharide produced by a mutant of Escherichia coli lacking glycogen synthase and maltodextrin phosphorylase.

Stability of the cancer target DDIAS is regulated by the CHIP/HSP70 pathway in lung cancer cells

Suppression of HIF-1α accumulation by betulinic acid through proteasome activation in hypoxic cervical cancer

Synthesis and biological evaluation of benzamides and benzamidines as selective inhibitors of VEGFR tyrosine kinases

Synthesis and biological evaluation of kresoxim-methyl analogues as novel inhibitors of hypoxia-inducible factor (HIF)-1 accumulation in cancer cells.

Synthesis and structure-activity relationship study of chemical probes as hypoxia induced factor-1α/malate dehydrogenase 2 inhibitors.

The Epigenetic Regulation of HCC Metastasis

The Roles of Hypoxia-Inducible Factors and Non-Coding RNAs in Gastrointestinal Cancer

The novel hypoxia-inducible factor-1α inhibitor IDF-11774 regulates cancer metabolism, thereby suppressing tumor growth.

o-Carboranylalkoxy-1,3,5-Triazine Derivatives: Synthesis, Characterization, X-ray Structural Studies, and Biological Activity

p300 cooperates with c-Jun and PARP-1 at the p300 binding site to activate RhoB transcription in NSC126188-mediated apoptosis