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List of works by Sergio Portal-Núñez

2017 update on the relationship between diabetes and colorectal cancer: epidemiology, potential molecular mechanisms and therapeutic implications

scientific article

Activation of bombesin receptor Subtype-3 by [D-Tyr 6 ,β-Ala 11 ,Phe 13 ,Nle 14 ]bombesin 6-14 increased glucose uptake and lipogenesis in human and rat adipocytes

scholarly article by Zaida Moreno-Villegas et al published October 2018 in Molecular and Cellular Endocrinology

Adverse Effects of Diabetes Mellitus on the Skeleton of Aging Mice

scientific article published on 18 September 2015

Alterations of the Wnt/β-catenin pathway and its target genes for the N- and C-terminal domains of parathyroid hormone-related protein in bone from diabetic mice

article

Aryl hydrocarbon receptor-induced adrenomedullin mediates cigarette smoke carcinogenicity in humans and mice.

scientific article

Autophagy impairment aggravates the inhibitory effects of high glucose on osteoblast viability and function

scientific journal article

Bombesin receptor subtype-3 (BRS-3), a novel candidate as therapeutic molecular target in obesity and diabetes

scientific article published on 3 January 2013

Characterization of Hybrid Bioactive Glass-polyvinyl Alcohol Scaffolds Containing a PTHrP-derived Pentapeptide as Implants for Tissue Engineering Applications

scientific article published on 07 March 2014

Characterization of skeletal alterations in a model of prematurely aging mice

scientific article published on 11 January 2012

Comparison of the osteoblastic activity conferred on Si-doped hydroxyapatite scaffolds by different osteostatin coatings

scientific article published on 14 June 2011

Comparison of the skeletal effects induced by daily administration of PTHrP (1-36) and PTHrP (107-139) to ovariectomized mice

scientific article published on 01 April 2012

Differentially expressed nucleolar transforming growth factor-beta1 target (DENTT) exhibits an inhibitory role on tumorigenesis

scientific article

Effect of bombesin receptor subtype-3 and its synthetic agonist on signaling, glucose transport and metabolism in myocytes from patients with obesity and type 2 diabetes

scientific article

Evaluation of bacterial adherence of clinical isolates of Staphylococcus sp. using a competitive model: An in vitro approach to the "race for the surface" theory.

scientific article

Fisiopatología del envejecimiento óseo

scientific article published on 14 December 2011

Functional roles of the nuclear localization signal of parathyroid hormone-related protein (PTHrP) in osteoblastic cells

scientific article published on 11 April 2014

Handling Parathormone Receptor Type 1 in Skeletal Diseases: Realities and Expectations of Abaloparatide

scientific article published on 11 August 2019

Human BRS-3 receptor: functions/role in cell signaling pathways and glucose metabolism in obese or diabetic myocytes

scientific article

Inhibition of the canonical Wnt pathway by high glucose can be reversed by parathyroid hormone-related protein in osteoblastic cells

scientific article published on August 2013

Local delivery of parathyroid hormone-related protein-derived peptides coated onto a hydroxyapatite-based implant enhances bone regeneration in old and diabetic rats.

scientific article published on 18 April 2016

Molecular basis for agonist selectivity and activation of the orphan bombesin receptor subtype 3 receptor.

scientific article published on 15 November 2007

Molecular evidence of field cancerization initiated by diabetes in colon cancer patients

scientific article published on 16 February 2019

Osteostatin improves the osteogenic activity of fibroblast growth factor-2 immobilized in Si-doped hydroxyapatite in osteoblastic cells

scientific article

Oxidative stress, autophagy, epigenetic changes and regulation by miRNAs as potential therapeutic targets in osteoarthritis

scientific article published on 19 December 2015

Parathyroid Hormone-Related Protein Analogs as Osteoporosis Therapies

scientific article published on 11 August 2015

Parathyroid Hormone-Related Protein Protects Osteoblastic Cells From Oxidative Stress by Activation of MKP1 Phosphatase

scientific article published on 30 June 2016

Parathyroid hormone-related protein (107-111) improves the bone regeneration potential of gelatin-glutaraldehyde biopolymer-coated hydroxyapatite.

scientific article published on 2 April 2014

Parathyroid hormone-related protein exhibits antioxidant features in osteoblastic cells through its N-terminal and osteostatin domains.

scientific article published in January 2018

Peptide inhibitors of hepatitis C virus NS3 protease

scientific article published in September 2003

Presence of a functional receptor for GLP-1 in osteoblastic cells, independent of the cAMP-linked GLP-1 receptor

scientific article published on November 2010

Proadrenomedullin NH2-terminal 20 peptide is a potent angiogenic factor, and its inhibition results in reduction of tumor growth

scientific article published on September 2004

Role of Oxidative Stress in Bone Ageing

Role of the N- and C-terminal fragments of parathyroid-hormone-related protein as putative therapies to improve bone regeneration under high glucocorticoid treatment

scientific article published in April 2010

The C-terminal fragment of parathyroid hormone-related peptide promotes bone formation in diabetic mice with low-turnover osteopaenia

scientific article published on March 2011

The central role of adrenomedullin in host defense

scientific article published on 12 June 2006

The combined therapy with chondroitin sulfate plus glucosamine sulfate or chondroitin sulfate plus glucosamine hydrochloride does not improve joint damage in an experimental model of knee osteoarthritis in rabbits

scientific article published on 11 November 2016

The vertebrae of prematurely aging mice as a skeletal model of involutional osteoporosis.

scientific article published on 15 May 2013

Treatment with N- and C-terminal peptides of parathyroid hormone-related protein partly compensate the skeletal abnormalities in IGF-I deficient mice

scientific article

Unexpected Bone Formation Produced by RANKL Blockade.

scientific article