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List of works by Przemysław Juszczyński

A novel, dual pan-PIM/FLT3 inhibitor SEL24 exhibits broad therapeutic potential in acute myeloid leukemia.

scientific article published on 30 March 2018

AP1-dependent galectin-1 expression delineates classical hodgkin and anaplastic large cell lymphomas from other lymphoid malignancies with shared molecular features

scientific article published on 01 June 2008

Association of human leukocyte antigen ancestral haplotype 8.1 with adverse outcome of non-Hodgkin's lymphoma.

scientific article published on May 2007

BAL1 and BBAP are regulated by a gamma interferon-responsive bidirectional promoter and are overexpressed in diffuse large B-cell lymphomas with a prominent inflammatory infiltrate

scientific article

BBAP monoubiquitylates histone H4 at lysine 91 and selectively modulates the DNA damage response

scientific article

BCL6 modulates tonic BCR signaling in diffuse large B-cell lymphomas by repressing the SYK phosphatase, PTPROt.

scientific article published on 23 October 2009

BCL6 programs lymphoma cells for survival and differentiation through distinct biochemical mechanisms

scientific article

BRAF inhibition curtails IFN-gamma-inducible PD-L1 expression and upregulates the immunoregulatory protein galectin-1 in melanoma cells

scientific article published on 24 April 2020

CXCR4 upregulation is an indicator of sensitivity to B-cell receptor/PI3K blockade and a potential resistance mechanism in B-cell receptor-dependent diffuse large B-cell lymphomas

scientific article published on 30 August 2019

Chronic eosinophilic leukemia with erythroblastic proliferation and the rare translocation t(8;9)(p22;p24) with PCM1-JAK2 fusion gene: a distinct clinical, pathological and genetic entity with potential treatment target?

scientific article published on 13 March 2012

Comparison of high-resolution melting analysis with direct sequencing for the detection of recurrent mutations in DNA methyltransferase 3A and isocitrate dehydrogenase 1 and 2 genes in acute myeloid leukemia patients.

scientific article published on 13 May 2015

Comparison of promoter DNA methylation and expression levels of genes encoding CCAAT/enhancer binding proteins in AML patients

scientific article published on 09 May 2014

Comparison study for genotyping of a single-nucleotide polymorphism in the tumor necrosis factor promoter gene

scientific article published on 01 December 2002

Constitutive AP-1 activity and EBV infection induce PD-L1 in Hodgkin lymphomas and posttransplant lymphoproliferative disorders: implications for targeted therapy

scientific article published on 23 January 2012

DEPTOR is a microRNA-155 target regulating migration and cytokine production in diffuse large B-cell lymphoma cells

scientific article published on 20 July 2020

Expression of PIM kinases in Reed-Sternberg cells fosters immune privilege and tumor cell survival in Hodgkin lymphoma.

scientific article published on 11 July 2017

Expression of the multidrug resistance-associated protein (mrp) gene in chronic lymphocytic leukemia

scientific article published on 01 January 2002

FOXO1 activation is an effector of SYK and AKT inhibition in tonic BCR signal-dependent diffuse large B-cell lymphomas.

scientific article published on 19 November 2015

FOXO1 is a TXN- and p300-dependent sensor and effector of oxidative stress in diffuse large B-cell lymphomas characterized by increased oxidative metabolism

scientific article

FOXO1 promotes resistance of non-Hodgkin lymphomas to anti-CD20-based therapy

scientific article published on 25 January 2018

FOXO1 transcription factor: a critical effector of the PI3K-AKT axis in B-cell development

scientific article

Haplotype-specific pattern of association of human major histocompatibility complex with non-Hodgkin's lymphoma outcome.

scientific article published on 29 October 2007

Host immune response in B-cell lymphomas: friend or foe?

scientific article published on 29 July 2008

Human leukocyte antigens HLA DRB1 influence clinical outcome of chronic lymphocytic leukemia?

scientific article published on 01 May 2007

Human leukocyte antigens class II and tumor necrosis factor genetic polymorphisms are independent predictors of non-Hodgkin lymphoma outcome

scientific article published in October 2002

Increased expression of E3 ubiquitin ligases targeting p53 in CLL patients with wild-type TP53 exhibits associations with clinical features of the disease.

scientific article published on 16 November 2015

Inhibition of protein disulfide isomerase induces differentiation of acute myeloid leukemia cells

scientific article published on 12 July 2018

Inhibitors of SRC kinases impair antitumor activity of anti-CD20 monoclonal antibodies.

scientific article

Integrative analysis reveals selective 9p24.1 amplification, increased PD-1 ligand expression, and further induction via JAK2 in nodular sclerosing Hodgkin lymphoma and primary mediastinal large B-cell lymphoma.

scientific article

MEK Inhibition Sensitizes Precursor B-Cell Acute Lymphoblastic Leukemia (B-ALL) Cells to Dexamethasone through Modulation of mTOR Activity and Stimulation of Autophagy

scientific article

MLL-rearranged B lymphoblastic leukemias selectively express the immunoregulatory carbohydrate-binding protein galectin-1.

scientific article

MYC deregulation in lymphoid tumors: molecular mechanisms, clinical consequences and therapeutic implications

scientific article published on 06 September 2014

MiR-17-92 represses PTPROt and PP2A phosphatases and amplifies tonic BCR signaling in DLBCL cells.

scientific article published on 06 October 2016

Microenvironment-induced PIM kinases promote CXCR4-triggered mTOR pathway required for chronic lymphocytic leukaemia cell migration.

scientific article published on 17 April 2018

New insights into redox homeostasis as a therapeutic target in B-cell malignancies.

scientific article

P044: PIM kinases support protumoral and immunosuppressive phenotype and functions of macrophages in classical Hodgkin Lymphoma

scientific article published in 2022

PIM kinases promote survival and immune escape in primary mediastinal large B-cell lymphoma through modulation of JAK-STAT and NFκB activity

scientific article published on 08 December 2020

Predictive significance of selected gene mutations in relapsed and refractory chronic lymphocytic leukemia patients treated with ibrutinib

scientific article published on 15 November 2020

Promoter DNA methylation and expression levels of HOXA4, HOXA5 and MEIS1 in acute myeloid leukemia.

scientific article published on 13 January 2015

Protein tyrosine phosphatase receptor-type O truncated (PTPROt) regulates SYK phosphorylation, proximal B-cell-receptor signaling, and cellular proliferation

scientific article

Rebelled epigenome: histone H3S10 phosphorylation and H3S10 kinases in cancer biology and therapy

scientific article published on 14 October 2020

Repetitive genomic elements and overall DNA methylation changes in acute myeloid and childhood B-cell lymphoblastic leukemia patients

scientific article published on 20 May 2014

SYK inhibition modulates distinct PI3K/AKT- dependent survival pathways and cholesterol biosynthesis in diffuse large B cell lymphomas

scientific article published on June 2013

SYK inhibition targets acute myeloid leukemia stem cells by blocking their oxidative metabolism

scientific article published on 06 November 2020

SYK-dependent tonic B-cell receptor signaling is a rational treatment target in diffuse large B-cell lymphoma

scientific article

Serine Biosynthesis Pathway Supports MYC-miR-494-EZH2 Feed-Forward Circuit Necessary to Maintain Metabolic and Epigenetic Reprogramming of Burkitt Lymphoma Cells

scientific article published on 03 March 2020

Targeting the thioredoxin system as a novel strategy against B-cell acute lymphoblastic leukemia

scientific article published on 05 April 2019

The AP1-dependent secretion of galectin-1 by Reed Sternberg cells fosters immune privilege in classical Hodgkin lymphoma

scholarly article

The heat shock protein 90 inhibitor IPI-504 induces apoptosis of AKT-dependent diffuse large B-cell lymphomas.

scientific article

Transcriptional signature with differential expression of BCL6 target genes accurately identifies BCL6-dependent diffuse large B cell lymphomas.

scholarly article

Viral induction and targeted inhibition of galectin-1 in EBV+ posttransplant lymphoproliferative disorders

scientific article published on 7 February 2011

[The role of HLA DRB1 genetic polymorphisms in non-Hodgkin's lymphomas]

scientific article published on 01 January 2005

[The role of genetic polymorphisms within tumor necrosis factor promoter gene in non-Hodgkin's lymphomas]

scientific article published on 01 January 2005

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