List of works - Byungkook Lee

A binding domain on mesothelin for CA125/MUC16

scientific article

A model for obesity and gigantism due to disruption of the Ankrd26 gene

scientific journal article

A recombinant immunotoxin engineered for increased stability by adding a disulfide bond has decreased immunogenicity.

scientific article published on 17 November 2011

Accuracy of structure-based sequence alignment of automatic methods

scientific article

Anoctamin and transmembrane channel-like proteins are evolutionarily related.

scientific article published on July 2009

Antigen shedding may improve efficiencies for delivery of antibody-based anticancer agents in solid tumors

scientific article

Assessment of CASP10 contact-assisted predictions.

scientific article

Assessment of CASP6 predictions for new and nearly new fold targets

scientific article

Assessment of template-free modeling in CASP10 and ROLL.

scientific article

Cloning, molecular characterization, and expression analysis of Copine 8.

scientific article

Composition bias and the origin of ORFan genes

scientific article

Context-specific amino acid substitution matrices and their use in the detection of protein homologs

scientific article

DOMIRE: a web server for identifying structural domains and their neighbors in proteins ⬇️

scientific article published on February 15, 2012

Definition and classification of evaluation units for CASP10

scientific article

Detecting internally symmetric protein structures

scientific article

Discovery of the breast cancer gene BASE using a molecular approach to enrich for genes encoding membrane and secreted proteins

scientific article

Effect of antigen shedding on targeted delivery of immunotoxins in solid tumors from a mathematical model

scientific article

Evaluation of domain prediction in CASP6.

scientific article

Evolution and expression of chimeric POTE-actin genes in the human genome

scholarly article

Finding fusion genes resulting from chromosome rearrangement by analyzing the expressed sequence databases

scholarly article

Five POTE paralogs and their splice variants are expressed in human prostate and encode proteins of different lengths

scientific article published on August 2004

Frequency of gaps observed in a structurally aligned protein pair database suggests a simple gap penalty function

scientific article

High expression of a cytokeratin-associated protein in many cancers

scientific article

Human-specific nonsense mutations identified by genome sequence comparisons

scientific article

Hydration entropy change from the hard sphere model.

scientific article published on December 2002

Iterative refinement of structure-based sequence alignments by Seed Extension

scientific article

MRP9, an unusual truncated member of the ABC transporter superfamily, is highly expressed in breast cancer

scientific article

Mesothelin, Stereocilin, and Otoancorin are predicted to have superhelical structures with ARM-type repeats

scientific article

Mesothelin-MUC16 binding is a high affinity, N-glycan dependent interaction that facilitates peritoneal metastasis of ovarian tumors

scientific article

Molecular Models of STAT5A Tetramers Complexed to DNA Predict Relative Genome-Wide Frequencies of the Spacing between the Two Dimer Binding Motifs of the Tetramer Binding Sites

scientific article (publication date: 2016)

Mutants of immunotoxin anti-Tac(dsFv)-PE38 with variable number of lysine residues as candidates for site-specific chemical modification. 1. Properties of mutant molecules

scientific article published in March 2003

NGEP, a gene encoding a membrane protein detected only in prostate cancer and normal prostate

scientific article

NGEP, a prostate-specific plasma membrane protein that promotes the association of LNCaP cells.

scientific article published on February 2007

Neighbor Overlap Is Enriched in the Yeast Interaction Network: Analysis and Implications ⬇️

scientific article published on June 26, 2012

On the intactness of hydrogen bonds around nonpolar solutes dissolved in water

scientific article published on April 2005

PATE gene clusters code for multiple, secreted TFP/Ly-6/uPAR proteins that are expressed in reproductive and neuron-rich tissues and possess neuromodulatory activity

scientific article

POTE paralogs are induced and differentially expressed in many cancers.

scientific article published on January 2006

POTE, a highly homologous gene family located on numerous chromosomes and expressed in prostate, ovary, testis, placenta, and prostate cancer

scientific article

PRAC2: A new gene expressed in human prostate and prostate cancer ⬇️

scientific article published on July 1, 2003

Poor correlation between T-cell activation assays and HLA-DR binding prediction algorithms in an immunogenic fragment of Pseudomonas exotoxin A.

scientific article

Protein domain assignment from the recurrence of locally similar structures ⬇️

scientific article published on December 22, 2010

ROC and confusion analysis of structure comparison methods identify the main causes of divergence from manual protein classification

scientific article

Recombinant immunotoxin against B-cell malignancies with no immunogenicity in mice by removal of B-cell epitopes.

scientific article

Recombinant immunotoxin engineered for low immunogenicity and antigenicity by identifying and silencing human B-cell epitopes

scientific article

Recombinant immunotoxin for cancer treatment with low immunogenicity by identification and silencing of human T-cell epitopes

scientific article

SE: an algorithm for deriving sequence alignment from a pair of superimposed structures

scientific article

Selective POTE paralogs on chromosome 2 are expressed in human embryonic stem cells.

scientific article

SymD webserver: a platform for detecting internally symmetric protein structures

scientific article

TEPP, a new gene specifically expressed in testis, prostate, and placenta and well conserved in chordates

scientific journal article

Topology of NGEP, a prostate-specific cell:cell junction protein widely expressed in many cancers of different grade level

scientific article published on August 2008

Towards an automatic classification of protein structural domains based on structural similarity

scientific article

List of works by Byungkook Lee

A binding domain on mesothelin for CA125/MUC16

A model for obesity and gigantism due to disruption of the Ankrd26 gene

A recombinant immunotoxin engineered for increased stability by adding a disulfide bond has decreased immunogenicity.

Accuracy of structure-based sequence alignment of automatic methods

Anoctamin and transmembrane channel-like proteins are evolutionarily related.

Antigen shedding may improve efficiencies for delivery of antibody-based anticancer agents in solid tumors

Assessment of CASP10 contact-assisted predictions.

Assessment of CASP6 predictions for new and nearly new fold targets

Assessment of template-free modeling in CASP10 and ROLL.

Cloning, molecular characterization, and expression analysis of Copine 8.

Composition bias and the origin of ORFan genes

Context-specific amino acid substitution matrices and their use in the detection of protein homologs

DOMIRE: a web server for identifying structural domains and their neighbors in proteins ⬇️

Definition and classification of evaluation units for CASP10

Detecting internally symmetric protein structures

Discovery of the breast cancer gene BASE using a molecular approach to enrich for genes encoding membrane and secreted proteins

Effect of antigen shedding on targeted delivery of immunotoxins in solid tumors from a mathematical model

Evaluation of domain prediction in CASP6.

Evolution and expression of chimeric POTE-actin genes in the human genome

Finding fusion genes resulting from chromosome rearrangement by analyzing the expressed sequence databases

Five POTE paralogs and their splice variants are expressed in human prostate and encode proteins of different lengths

Frequency of gaps observed in a structurally aligned protein pair database suggests a simple gap penalty function

High expression of a cytokeratin-associated protein in many cancers

Human-specific nonsense mutations identified by genome sequence comparisons

Hydration entropy change from the hard sphere model.

Iterative refinement of structure-based sequence alignments by Seed Extension

MRP9, an unusual truncated member of the ABC transporter superfamily, is highly expressed in breast cancer

Mesothelin, Stereocilin, and Otoancorin are predicted to have superhelical structures with ARM-type repeats

Mesothelin-MUC16 binding is a high affinity, N-glycan dependent interaction that facilitates peritoneal metastasis of ovarian tumors

Molecular Models of STAT5A Tetramers Complexed to DNA Predict Relative Genome-Wide Frequencies of the Spacing between the Two Dimer Binding Motifs of the Tetramer Binding Sites

Mutants of immunotoxin anti-Tac(dsFv)-PE38 with variable number of lysine residues as candidates for site-specific chemical modification. 1. Properties of mutant molecules

NGEP, a gene encoding a membrane protein detected only in prostate cancer and normal prostate

NGEP, a prostate-specific plasma membrane protein that promotes the association of LNCaP cells.

Neighbor Overlap Is Enriched in the Yeast Interaction Network: Analysis and Implications ⬇️

On the intactness of hydrogen bonds around nonpolar solutes dissolved in water

PATE gene clusters code for multiple, secreted TFP/Ly-6/uPAR proteins that are expressed in reproductive and neuron-rich tissues and possess neuromodulatory activity

POTE paralogs are induced and differentially expressed in many cancers.

POTE, a highly homologous gene family located on numerous chromosomes and expressed in prostate, ovary, testis, placenta, and prostate cancer

PRAC2: A new gene expressed in human prostate and prostate cancer ⬇️

Poor correlation between T-cell activation assays and HLA-DR binding prediction algorithms in an immunogenic fragment of Pseudomonas exotoxin A.

Protein domain assignment from the recurrence of locally similar structures ⬇️

ROC and confusion analysis of structure comparison methods identify the main causes of divergence from manual protein classification

Recombinant immunotoxin against B-cell malignancies with no immunogenicity in mice by removal of B-cell epitopes.

Recombinant immunotoxin engineered for low immunogenicity and antigenicity by identifying and silencing human B-cell epitopes

Recombinant immunotoxin for cancer treatment with low immunogenicity by identification and silencing of human T-cell epitopes

SE: an algorithm for deriving sequence alignment from a pair of superimposed structures

Selective POTE paralogs on chromosome 2 are expressed in human embryonic stem cells.

SymD webserver: a platform for detecting internally symmetric protein structures

TEPP, a new gene specifically expressed in testis, prostate, and placenta and well conserved in chordates

Topology of NGEP, a prostate-specific cell:cell junction protein widely expressed in many cancers of different grade level

Towards an automatic classification of protein structural domains based on structural similarity