List of works - Kira Irina Astakhova

"Clickable" LNA/DNA probes for fluorescence sensing of nucleic acids and autoimmune antibodies.

scientific article published in November 2013

"Clicking" gene therapeutics: A successful union of chemistry and biomedicine for new solutions.

scientific article published on 4 January 2018

A locked nucleic acid-based nanocrawler: designed and reversible movement detected by multicolor fluorescence.

scientific article published on 8 February 2013

Antibodies to synthetic citrullinated peptide epitope correlate with disease activity and flares in rheumatoid arthritis

scientific article published on 23 April 2020

Antisense Oligonucleotides Internally Labeled with Peptides Show Improved Target Recognition and Stability to Enzymatic Degradation

scientific article

Autoantibodies in Morphea: An Update

scientific article published on 09 July 2019

Autoantibody Profiling in Lupus Patients using Synthetic Nucleic Acids.

scientific article published on 3 April 2018

Branched DNA nanostructures efficiently stabilised and monitored by novel pyrene–perylene 2′-α-l-amino-LNA FRET pairs

scientific article published on 01 January 2013

Citrullinated Peptide Epitope Targets Therapeutic Nanoparticles to Human Neutrophils

scientific article published on 27 September 2019

Combination of ichthyosis with Recklinghausen's disease

scientific article published on November 1, 1976

Combined Assay for Detecting Autoantibodies to Nucleic Acids and Apolipoprotein H in Patients with Systemic Lupus Erythematosus

scientific article published on 01 January 2020

Complexes of DNA with fluorescent dyes are effective reagents for detection of autoimmune antibodies.

scientific article

Condition of the paranasal sinuses in respiratory system diseases

scientific article published on 01 July 1981

Control of LDL Uptake in Human Cells by Targeting the LDLR Regulatory Long Non-coding RNA BM450697

scientific article published on 07 June 2019

Detection of autoimmune antibodies in localized scleroderma by synthetic oligonucleotide antigens.

scientific article published on 11 April 2018

Dihydropyridine Fluorophores Allow for Specific Detection of Human Antibodies in Serum.

scientific article published on 10 July 2018

Environmentally sensitive molecular probes reveal mutations and epigenetic 5-methyl cytosine in human oncogenes.

scientific article published on 27 June 2017

Enzyme-Free Detection of Mutations in Cancer DNA Using Synthetic Oligonucleotide Probes and Fluorescence Microscopy

scientific article published on 27 August 2015

Fluorescent Oligonucleotides with Bis(prop-2-yn-1-yloxy)butane-1,3-diol Scaffold Rapidly Detect Disease-Associated Nucleic Acids

scientific article published on 04 December 2019

Highly fluorescent conjugated pyrenes in nucleic acid probes: (phenylethynyl)pyrenecarbonyl-functionalized locked nucleic acids.

scientific article

Improving the Design of Synthetic Oligonucleotide Probes by Fluorescence Melting Assay

scientific article published on 27 November 2018

Interfacing click chemistry with automated oligonucleotide synthesis for the preparation of fluorescent DNA probes containing internal xanthene and cyanine dyes.

scientific article

LNA for optimization of fluorescent oligonucleotide probes: improved spectral properties and target binding.

scientific article

Lipid Nanoparticles for Delivery of Therapeutic RNA Oligonucleotides

scientific article published on 16 May 2019

New Fluorescent Nanoparticles for Ultrasensitive Detection of Nucleic Acids by Optical Methods

scientific article

Novel (phenylethynyl)pyrene-LNA constructs for fluorescence SNP sensing in polymorphic nucleic acid targets.

scientific article

Novel Phospholipid-Protein Conjugates Allow Improved Detection of Antibodies in Patients with Autoimmune Diseases

scientific article

Otorhinolaryngologic pathology in porphyria cutanea tarda

scientific article published on 01 January 1971

Para-influenza and paramyxovirus carrier state in chronic bronchitis and bronchial asthma

scientific article published on 01 January 1983

Peptide-Fluorophore Hydrogel as a Signal Boosting Approach in Rapid Detection of Cancer DNA

scientific article published on 16 August 2019

Peptide-LNA oligonucleotide conjugates.

scientific article published on July 2013

Perylene attached to 2'-amino-LNA: synthesis, incorporation into oligonucleotides, and remarkable fluorescence properties in vitro and in cell culture.

scientific article published on 5 September 2008

Phenylethynylpyrene excimer forming hybridization probes for fluorescence SNP detection.

scientific article published in January 2009

Rapid genotyping using pyrene-perylene locked nucleic acid complexes.

scientific article published on April 2013

Reactive trityl derivatives: stabilised carbocation mass-tags for life sciences applications.

scientific article

Revealing Nucleic Acid Mutations Using Förster Resonance Energy Transfer-Based Probes

scientific article

Scaffolding along nucleic acid duplexes using 2'-amino-locked nucleic acids.

scientific article published on 21 April 2014

Serological comparison of systemic lupus erythematosus with neuropsychiatric lupus using synthetic nucleic acid antigens

scientific article published on 28 October 2020

Solid-Phase Hybridization Assay for Detection of Mutated Cancer DNA by Fluorescence

scientific article published on 01 January 2020

Studies of Impending Oligonucleotide Therapeutics in Simulated Biofluids

scientific article published on 14 August 2018

Synthesis of Phospholipid-Protein Conjugates as New Antigens for Autoimmune Antibodies.

scientific article published on 3 June 2015

Synthetic Nucleic Acid Analogues in Gene Therapy: An Update for Peptide-Oligonucleotide Conjugates

scientific article

Synthetic oligonucleotide antigens modified with locked nucleic acids detect disease specific antibodies

scientific article published on 24 October 2016

Tandem Oligonucleotide Probe Annealing and Elongation To Discriminate Viral Sequence

scientific article

Ultra-fast detection and quantification of nucleic acids by amplification-free fluorescence assay

scientific article published on 10 July 2020

Ultramild protein-mediated click chemistry creates efficient oligonucleotide probes for targeting and detecting nucleic acids

scientific article published on 04 May 2015

List of works by Kira Irina Astakhova

"Clickable" LNA/DNA probes for fluorescence sensing of nucleic acids and autoimmune antibodies.

"Clicking" gene therapeutics: A successful union of chemistry and biomedicine for new solutions.

A locked nucleic acid-based nanocrawler: designed and reversible movement detected by multicolor fluorescence.

Antibodies to synthetic citrullinated peptide epitope correlate with disease activity and flares in rheumatoid arthritis

Antisense Oligonucleotides Internally Labeled with Peptides Show Improved Target Recognition and Stability to Enzymatic Degradation

Autoantibodies in Morphea: An Update

Autoantibody Profiling in Lupus Patients using Synthetic Nucleic Acids.

Branched DNA nanostructures efficiently stabilised and monitored by novel pyrene–perylene 2′-α-l-amino-LNA FRET pairs

Citrullinated Peptide Epitope Targets Therapeutic Nanoparticles to Human Neutrophils

Combination of ichthyosis with Recklinghausen's disease

Combined Assay for Detecting Autoantibodies to Nucleic Acids and Apolipoprotein H in Patients with Systemic Lupus Erythematosus

Complexes of DNA with fluorescent dyes are effective reagents for detection of autoimmune antibodies.

Condition of the paranasal sinuses in respiratory system diseases

Control of LDL Uptake in Human Cells by Targeting the LDLR Regulatory Long Non-coding RNA BM450697

Detection of autoimmune antibodies in localized scleroderma by synthetic oligonucleotide antigens.

Dihydropyridine Fluorophores Allow for Specific Detection of Human Antibodies in Serum.

Environmentally sensitive molecular probes reveal mutations and epigenetic 5-methyl cytosine in human oncogenes.

Enzyme-Free Detection of Mutations in Cancer DNA Using Synthetic Oligonucleotide Probes and Fluorescence Microscopy

Fluorescent Oligonucleotides with Bis(prop-2-yn-1-yloxy)butane-1,3-diol Scaffold Rapidly Detect Disease-Associated Nucleic Acids

Highly fluorescent conjugated pyrenes in nucleic acid probes: (phenylethynyl)pyrenecarbonyl-functionalized locked nucleic acids.

Improving the Design of Synthetic Oligonucleotide Probes by Fluorescence Melting Assay

Interfacing click chemistry with automated oligonucleotide synthesis for the preparation of fluorescent DNA probes containing internal xanthene and cyanine dyes.

LNA for optimization of fluorescent oligonucleotide probes: improved spectral properties and target binding.

Lipid Nanoparticles for Delivery of Therapeutic RNA Oligonucleotides

New Fluorescent Nanoparticles for Ultrasensitive Detection of Nucleic Acids by Optical Methods

Novel (phenylethynyl)pyrene-LNA constructs for fluorescence SNP sensing in polymorphic nucleic acid targets.

Novel Phospholipid-Protein Conjugates Allow Improved Detection of Antibodies in Patients with Autoimmune Diseases

Otorhinolaryngologic pathology in porphyria cutanea tarda

Para-influenza and paramyxovirus carrier state in chronic bronchitis and bronchial asthma

Peptide-Fluorophore Hydrogel as a Signal Boosting Approach in Rapid Detection of Cancer DNA

Peptide-LNA oligonucleotide conjugates.

Perylene attached to 2'-amino-LNA: synthesis, incorporation into oligonucleotides, and remarkable fluorescence properties in vitro and in cell culture.

Phenylethynylpyrene excimer forming hybridization probes for fluorescence SNP detection.

Rapid genotyping using pyrene-perylene locked nucleic acid complexes.

Reactive trityl derivatives: stabilised carbocation mass-tags for life sciences applications.

Revealing Nucleic Acid Mutations Using Förster Resonance Energy Transfer-Based Probes

Scaffolding along nucleic acid duplexes using 2'-amino-locked nucleic acids.

Serological comparison of systemic lupus erythematosus with neuropsychiatric lupus using synthetic nucleic acid antigens

Solid-Phase Hybridization Assay for Detection of Mutated Cancer DNA by Fluorescence

Studies of Impending Oligonucleotide Therapeutics in Simulated Biofluids

Synthesis of Phospholipid-Protein Conjugates as New Antigens for Autoimmune Antibodies.

Synthetic Nucleic Acid Analogues in Gene Therapy: An Update for Peptide-Oligonucleotide Conjugates

Synthetic oligonucleotide antigens modified with locked nucleic acids detect disease specific antibodies

Tandem Oligonucleotide Probe Annealing and Elongation To Discriminate Viral Sequence

Ultra-fast detection and quantification of nucleic acids by amplification-free fluorescence assay

Ultramild protein-mediated click chemistry creates efficient oligonucleotide probes for targeting and detecting nucleic acids