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List of works by Roque Bort

A combination of transcriptomics and metabolomics uncovers enhanced bile acid biosynthesis in HepG2 cells expressing CCAAT/enhancer-binding protein β (C/EBPβ), hepatocyte nuclear factor 4α (HNF4α), and constitutive androstane receptor (CAR).

scientific article published on 15 May 2013

Biotransformation in vitro of the 22R and 22S epimers of budesonide by human liver, bronchus, colonic mucosa and skin.

scientific article

Direct conversion of human fibroblast to hepatocytes using a single inducible polycistronic vector

scientific article published on 04 November 2019

Early ERK1/2 activation promotes DRP1-dependent mitochondrial fission necessary for cell reprogramming

scientific article published on 31 March 2016

Gata4 blocks somatic cell reprogramming by directly repressing Nanog.

scientific article

Glutamine/glutamate metabolism rewiring in reprogrammed human hepatocyte-like cells

scientific article published on 29 November 2019

Growth-promoting and tumourigenic activity of c-Myc is suppressed by Hhex

scientific article published on 15 September 2014

Hepatic cytochrome P450 down-regulation during aseptic inflammation in the mouse is interleukin 6 dependent

scientific article published on 01 July 2000

Hex homeobox gene-dependent tissue positioning is required for organogenesis of the ventral pancreas

scientific journal article

Increased toxicity of cocaine on human hepatocytes induced by ethanol: role of GSH.

scientific article published in November 1999

Interaction between Hhex and SOX13 modulates Wnt/TCF activity

scientific article

Long-term expression of differentiated functions in hepatocytes cultured in three-dimensional collagen matrix

scientific article published on 01 December 1998

Maturation of induced pluripotent stem cell derived hepatocytes by 3D-culture

scientific article (publication date: 2014)

Molecular mechanism of diclofenac hepatotoxicity: Association of cell injury with oxidative metabolism and decrease in ATP levels

scientific article published on 01 August 1995

Paths to the pancreas

scientific article published on 01 September 2002

Purification and characterization of a new α-amylase of intermediate thermal stability from the yeast Lipomyces kononenkoae

scientific article published in January 1995

Re-expression of C/EBPα induces CYP2B6, CYP2C9 and CYP2D6 genes in HepG2 cells

article

Role of hepatocyte nuclear factor 3 gamma in the expression of human CYP2C genes.

scientific article published on June 2004

Silencing of hepatic fate-conversion factors induce tumorigenesis in reprogrammed hepatic progenitor-like cells.

scientific article published on 27 July 2016

Transcriptomic responses generated by hepatocarcinogens in a battery of liver-based in vitro models

scientific article published on 7 February 2013

Transfection of Primary Hepatocytes with Liver-Enriched Transcription Factors Using Adenoviral Vectors

scientific article

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