List of works - Masataka Kawai

A re-interpretation of the rate of tension redevelopment (k(TR)) in active muscle.

scientific article published on 27 October 2013

A study of tropomyosin’s role in cardiac function and disease using thin-filament reconstituted myocardium ⬇️

scientific article published on May 23, 2013

ATP binding and cross-bridge detachment steps during full Ca²⁺ activation: comparison of myofibril and muscle fibre mechanics by sinusoidal analysis

scientific article published on 14 May 2012

Alternate energy transduction routes in chemically skinned rabbit psoas muscle fibres: a further study of the effect of MgATP over a wide concentration range

scientific article published on 01 June 1981

Analysis of the molecular pathogenesis of cardiomyopathy-causing cTnT mutants I79N, ΔE96, and ΔK210.

scientific article published on May 2013

Cardiac contractility, motor function, and cross-bridge kinetics in N47K-RLC mutant mice.

scientific article published on 3 May 2017

Cardiac myosin binding protein C phosphorylation affects cross-bridge cycle's elementary steps in a site-specific manner.

scientific article

Characterizations of myosin essential light chain's N-terminal truncation mutant Δ43 in transgenic mouse papillary muscles by using tension transients in response to sinusoidal length alterations.

scientific article published on 9 February 2013

Collagen in chemically skinned, extracted dystrophic myofibers

Comments on "Critical dependence of calcium-activated force on width in highly compressed skinned fibers of the frog".

scientific article published in December 1986

Comments on the paper by Dr. David Smith entitled "A strain-dependent ratchet model for [phosphate]- and [ATP]-dependent muscle contraction"

scientific article published on 01 August 1998

Comparison of crossbridge dynamics between intact and skinned myocardium from ferret right ventricles

scientific article published on 01 March 1991

Comparison of elementary steps of the cross-bridge cycle in rat papillary muscle fibers expressing α- and β-myosin heavy chain with sinusoidal analysis.

scientific article published on 10 December 2016

Correlation between cross-bridge kinetics obtained from Trp fluorescence of myofibril suspensions and mechanical studies of single muscle fibers in rabbit psoas.

scientific article published on 18 October 2011

Covalent cross-linking of single fibers from rabbit psoas increases oscillatory power.

scientific article published on March 1990

Cross-bridge scheme and force per cross-bridge state in skinned rabbit psoas muscle fibers.

scientific article

Crossbridge kinetics in chemically skinned rabbit psoas fibres when the actin-myosin lattice spacing is altered by dextran T-500.

scientific article

Crossbridge scheme and the kinetic constants of elementary steps deduced from chemically skinned papillary and trabecular muscles of the ferret

scientific article published on 01 July 1993

DCM-related tropomyosin mutants E40K/E54K over-inhibit the actomyosin interaction and lead to a decrease in the number of cycling cross-bridges.

scientific article

Dependence of energy transduction in intact skeletal muscles on the time in tension ⬇️

scientific article published on May 1, 1977

Development of apical hypertrophic cardiomyopathy with age in a transgenic mouse model carrying the cardiac actin E99K mutation

scientific article published on 01 December 2017

Differences in the transient response of fast and slow skeletal muscle fibers. Correlations between complex modulus and myosin light chains.

scientific article

Diversity and similarity of motor function and cross-bridge kinetics in papillary muscles of transgenic mice carrying myosin regulatory light chain mutations D166V and R58Q

scientific article published on 29 May 2013

Editorial on EMC 2014 special issue

scientific article published on 01 February 2015

Effect of ionic strength on crossbridge kinetics as studied by sinusoidal analysis, ATP hydrolysis rate and X-ray diffraction techniques in chemically skinned rabbit psoas fibres

scientific article published on 01 October 1990

Effect of temperature on elementary steps of the cross-bridge cycle in rabbit soleus slow-twitch muscle fibres

scientific article

Effectof MgATP on stiffness measured at two frequencies in Ca2+-activated muscle fibers ⬇️

scientific article published on September 1, 1977

Effects of MgATP and MgADP on the cross-bridge kinetics of rabbit soleus slow-twitch muscle fibers.

scientific article

Effects of tropomyosin internal deletion Delta23Tm on isometric tension and the cross-bridge kinetics in bovine myocardium.

scientific article published on 18 September 2003

Elementary steps of the cross-bridge cycle in fast-twitch fiber types from rabbit skeletal muscles.

scientific article

Enhanced active cross-bridges during diastole: molecular pathogenesis of tropomyosin's HCM mutations

scientific article

Estimation of actomyosin active force maintained by tropomyosin and troponin complex under vertical forces in the in vitro motility assay system

scientific article published on 8 February 2018

Force generation and phosphate release steps in skinned rabbit soleus slow-twitch muscle fibers ⬇️

scientific article published on August 1, 1997

Head rotation or dissociation? A study of exponential rate processes in chemically skinned rabbit muscle fibers when MgATP concentration is changed ⬇️

scientific article published on April 1, 1978

High ionic strength depresses muscle contractility by decreasing both force per cross-bridge and the number of strongly attached cross-bridges

scientific article published on 3 April 2015

Kawai's Response to Horiuti and Sakoda

Kinetic and thermodynamic studies of the cross-bridge cycle in rabbit psoas muscle fibers.

scientific article

Myosin Rod Hypophosphorylation and CB Kinetics in Papillary Muscles from a TnC-A8V KI Mouse Model.

scientific article published in April 2017

Nebulin increases thin filament stiffness and force per cross-bridge in slow-twitch soleus muscle fibers

article

Optical Diffraction Studies of Muscle Fibers ⬇️

scientific article published on September 1, 1973

Phosphorylation of cMyBP-C affects contractile mechanisms in a site-specific manner

scientific article

Role of the N-terminal negative charges of actin in force generation and cross-bridge kinetics in reconstituted bovine cardiac muscle fibres

scientific article published on 13 January 2005

Sinusoidal analysis: a high resolution method for correlating biochemical reactions with physiological processes in activated skeletal muscles of rabbit, frog and crayfish

scientific article published on 01 September 1980

Stiffness and contractile properties of avian normal and dystrophic muscle bundles as measured by sinusoidal length perturbations.

scientific article published in July 1985

Structural and functional aspects of the myosin essential light chain in cardiac muscle contraction.

scientific article published on September 2011

Temperature effect on isometric tension is mediated by regulatory proteins tropomyosin and troponin in bovine myocardium

scientific article published on 01 February 2002

The effect of inorganic phosphate on the ATP hydrolysis rate and the tension transients in chemically skinned rabbit psoas fibers

scientific article published on 01 January 1987

The effect of lattice spacing change on cross-bridge kinetics in chemically skinned rabbit psoas muscle fibers. I. Proportionality between the lattice spacing and the fiber width

scientific article

The effect of partial extraction of troponin C on the elementary steps of the cross-bridge cycle in rabbit psoas muscle fibers

scientific article

The effect of the lattice spacing change on cross-bridge kinetics in chemically skinned rabbit psoas muscle fibers. II. Elementary steps affected by the spacing change.

scientific article

The immediate effect of HCM causing actin mutants E99K and A230V on actin-Tm-myosin interaction in thin-filament reconstituted myocardium.

scientific article published on 5 November 2014

The role of collagen crosslinking in the increased stiffness of avian dystrophic muscle

scientific article published on 01 June 1989

The role of orthophosphate in crossbridge kinetics in chemically skinned rabbit psoas fibres as detected with sinusoidal and step length alterations

scientific article published on 01 October 1986

The role of tropomyosin domains in cooperative activation of the actin-myosin interaction.

scientific article published on 20 October 2011

Use of thin filament reconstituted muscle fibres to probe the mechanism of force generation.

scientific article published on 15 August 2006

Using baculovirus/insect cell expressed recombinant actin to study the molecular pathogenesis of HCM caused by actin mutation A331P

scientific article published on 30 April 2014

Voltage fluctuations at the frog sartorius motor endplate produced by a covalently attached activator ⬇️

scientific article published on December 14, 1979

What do we learn by studying the temperature effect on isometric tension and tension transients in mammalian striated muscle fibres?

scientific article published on January 1, 2003

List of works by Masataka Kawai

A re-interpretation of the rate of tension redevelopment (k(TR)) in active muscle.

A study of tropomyosin’s role in cardiac function and disease using thin-filament reconstituted myocardium ⬇️

ATP binding and cross-bridge detachment steps during full Ca²⁺ activation: comparison of myofibril and muscle fibre mechanics by sinusoidal analysis

Alternate energy transduction routes in chemically skinned rabbit psoas muscle fibres: a further study of the effect of MgATP over a wide concentration range

Analysis of the molecular pathogenesis of cardiomyopathy-causing cTnT mutants I79N, ΔE96, and ΔK210.

Cardiac contractility, motor function, and cross-bridge kinetics in N47K-RLC mutant mice.

Cardiac myosin binding protein C phosphorylation affects cross-bridge cycle's elementary steps in a site-specific manner.

Characterizations of myosin essential light chain's N-terminal truncation mutant Δ43 in transgenic mouse papillary muscles by using tension transients in response to sinusoidal length alterations.

Collagen in chemically skinned, extracted dystrophic myofibers

Comments on "Critical dependence of calcium-activated force on width in highly compressed skinned fibers of the frog".

Comments on the paper by Dr. David Smith entitled "A strain-dependent ratchet model for [phosphate]- and [ATP]-dependent muscle contraction"

Comparison of crossbridge dynamics between intact and skinned myocardium from ferret right ventricles

Comparison of elementary steps of the cross-bridge cycle in rat papillary muscle fibers expressing α- and β-myosin heavy chain with sinusoidal analysis.

Correlation between cross-bridge kinetics obtained from Trp fluorescence of myofibril suspensions and mechanical studies of single muscle fibers in rabbit psoas.

Covalent cross-linking of single fibers from rabbit psoas increases oscillatory power.

Cross-bridge scheme and force per cross-bridge state in skinned rabbit psoas muscle fibers.

Crossbridge kinetics in chemically skinned rabbit psoas fibres when the actin-myosin lattice spacing is altered by dextran T-500.

Crossbridge scheme and the kinetic constants of elementary steps deduced from chemically skinned papillary and trabecular muscles of the ferret

DCM-related tropomyosin mutants E40K/E54K over-inhibit the actomyosin interaction and lead to a decrease in the number of cycling cross-bridges.

Dependence of energy transduction in intact skeletal muscles on the time in tension ⬇️

Development of apical hypertrophic cardiomyopathy with age in a transgenic mouse model carrying the cardiac actin E99K mutation

Differences in the transient response of fast and slow skeletal muscle fibers. Correlations between complex modulus and myosin light chains.

Diversity and similarity of motor function and cross-bridge kinetics in papillary muscles of transgenic mice carrying myosin regulatory light chain mutations D166V and R58Q

Editorial on EMC 2014 special issue

Effect of ionic strength on crossbridge kinetics as studied by sinusoidal analysis, ATP hydrolysis rate and X-ray diffraction techniques in chemically skinned rabbit psoas fibres

Effect of temperature on elementary steps of the cross-bridge cycle in rabbit soleus slow-twitch muscle fibres

Effectof MgATP on stiffness measured at two frequencies in Ca2+-activated muscle fibers ⬇️

Effects of MgATP and MgADP on the cross-bridge kinetics of rabbit soleus slow-twitch muscle fibers.

Effects of tropomyosin internal deletion Delta23Tm on isometric tension and the cross-bridge kinetics in bovine myocardium.

Elementary steps of the cross-bridge cycle in fast-twitch fiber types from rabbit skeletal muscles.

Enhanced active cross-bridges during diastole: molecular pathogenesis of tropomyosin's HCM mutations

Estimation of actomyosin active force maintained by tropomyosin and troponin complex under vertical forces in the in vitro motility assay system

Force generation and phosphate release steps in skinned rabbit soleus slow-twitch muscle fibers ⬇️

Head rotation or dissociation? A study of exponential rate processes in chemically skinned rabbit muscle fibers when MgATP concentration is changed ⬇️

High ionic strength depresses muscle contractility by decreasing both force per cross-bridge and the number of strongly attached cross-bridges

Kawai's Response to Horiuti and Sakoda

Kinetic and thermodynamic studies of the cross-bridge cycle in rabbit psoas muscle fibers.

Myosin Rod Hypophosphorylation and CB Kinetics in Papillary Muscles from a TnC-A8V KI Mouse Model.

Nebulin increases thin filament stiffness and force per cross-bridge in slow-twitch soleus muscle fibers

Optical Diffraction Studies of Muscle Fibers ⬇️

Phosphorylation of cMyBP-C affects contractile mechanisms in a site-specific manner

Role of the N-terminal negative charges of actin in force generation and cross-bridge kinetics in reconstituted bovine cardiac muscle fibres

Sinusoidal analysis: a high resolution method for correlating biochemical reactions with physiological processes in activated skeletal muscles of rabbit, frog and crayfish

Stiffness and contractile properties of avian normal and dystrophic muscle bundles as measured by sinusoidal length perturbations.

Structural and functional aspects of the myosin essential light chain in cardiac muscle contraction.

Temperature effect on isometric tension is mediated by regulatory proteins tropomyosin and troponin in bovine myocardium

The effect of inorganic phosphate on the ATP hydrolysis rate and the tension transients in chemically skinned rabbit psoas fibers

The effect of lattice spacing change on cross-bridge kinetics in chemically skinned rabbit psoas muscle fibers. I. Proportionality between the lattice spacing and the fiber width

The effect of partial extraction of troponin C on the elementary steps of the cross-bridge cycle in rabbit psoas muscle fibers

The effect of the lattice spacing change on cross-bridge kinetics in chemically skinned rabbit psoas muscle fibers. II. Elementary steps affected by the spacing change.

The immediate effect of HCM causing actin mutants E99K and A230V on actin-Tm-myosin interaction in thin-filament reconstituted myocardium.

The role of collagen crosslinking in the increased stiffness of avian dystrophic muscle

The role of orthophosphate in crossbridge kinetics in chemically skinned rabbit psoas fibres as detected with sinusoidal and step length alterations

The role of tropomyosin domains in cooperative activation of the actin-myosin interaction.

Use of thin filament reconstituted muscle fibres to probe the mechanism of force generation.

Using baculovirus/insect cell expressed recombinant actin to study the molecular pathogenesis of HCM caused by actin mutation A331P

Voltage fluctuations at the frog sartorius motor endplate produced by a covalently attached activator ⬇️

What do we learn by studying the temperature effect on isometric tension and tension transients in mammalian striated muscle fibres?