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List of works by Nicolas Levoin

A combination of in silico and SAR studies to identify binding hot spots of Bcl-xL inhibitors.

scientific article published on 6 March 2015

A solid phase parallel synthesis of diverse amides as dopamine D3 receptor ligands

scientific article published on 01 October 2008

CD95-Mediated Calcium Signaling Promotes T Helper 17 Trafficking to Inflamed Organs in Lupus-Prone Mice

scientific article published on July 2016

Design, synthesis and biological evaluation of new inhibitors of Bax/Bcl-xL interaction in cancer cells

scientific article published on 24 February 2014

Determination of the binding mode and interacting amino-acids for dibasic H3 receptor antagonists

scientific article published on 2 June 2013

Discovery of nanomolar ligands with novel scaffolds for the histamine H4 receptor by virtual screening

scientific article

Disrupting the CD95–PLCγ1 interaction prevents Th17-driven inflammation

scientific article published on 14 November 2018

Elucidation of the mechanism of inhibition of cyclooxygenases by acyl-coenzyme A and acylglucuronic conjugates of ketoprofen.

scientific article published in November 2004

Homology Model Versus X-ray Structure in Receptor-based Drug Design: A Retrospective Analysis with the Dopamine D3 Receptor

scientific article

Improving selectivity of dopamine D3 receptor ligands

scientific article published on 21 December 2015

Induction of intracellular calcium concentration by environmental benzo(a)pyrene involves a β2-adrenergic receptor/adenylyl cyclase/Epac-1/inositol 1,4,5-trisphosphate pathway in endothelial cells.

scientific article published on 13 December 2011

Irreversible inhibition of glucose-6-phosphate dehydrogenase by the coenzyme A conjugate of ketoprofen: a key to oxidative stress induced by non-steroidal anti-inflammatory drugs?

scientific article published on 01 October 2006

Novel and highly potent histamine H3 receptor ligands. Part 1: withdrawing of hERG activity

scientific article published on 13 July 2011

Novel and highly potent histamine H3 receptor ligands. Part 2: exploring the cyclohexylamine-based series.

scientific article published on 28 June 2011

Novel and highly potent histamine H3 receptor ligands. Part 3: An alcohol function to improve the pharmacokinetic profile ⬇️

scientific article published on March 14, 2013

Probing the side chain tolerance for inhibitors of the CD95/PLCγ1 interaction

scientific article published on 07 September 2019

Refined docking as a valuable tool for lead optimization: application to histamine H3 receptor antagonists.

scientific article

Sketching of CD95 Oligomers by In Silico Investigations

scientific article

Synthesis and evaluation of a 2-benzothiazolylphenylmethyl ether class of histamine H4 receptor antagonists

scientific article published on 19 September 2016

Synthesis of peptidomimetics and chemo-biological tools for CD95/PLCγ1 interaction analysis

scientific article published on 05 July 2019

Targeting PUMA/Bcl-xL interaction by new specific compounds to unleash apoptotic process in cancer cells

scientific article published on 02 November 2018

The Prins reaction using ketones: rationalization and application toward the synthesis of the portentol skeleton

scientific article published on 30 November 2011

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