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List of works by Maria A Garcia

1-(Benzenesulfonyl)-1,5-dihydro-4,1-benzoxazepine as a new scaffold for the design of antitumor compounds

scientific article

5-Fluorouracil derivatives: a patent review (2012 - 2014).

scientific article published on 13 July 2015

A formulation of pancreatic pro-enzymes provides potent anti-tumour efficacy: a pilot study focused on pancreatic and ovarian cancer.

scientific article published on 25 October 2017

Activating Transcription Factor 4 Modulates TGFβ-Induced Aggressiveness in Triple-Negative Breast Cancer via SMAD2/3/4 and mTORC2 Signaling

scientific article published on 16 July 2018

Activation of NF-kB pathway by virus infection requires Rb expression

scientific article

Activation of the double-stranded RNA-dependent protein kinase PKR by small ubiquitin-like modifier (SUMO).

scientific article published on 29 July 2014

Anti-apoptotic and oncogenic properties of the dsRNA-binding protein of vaccinia virus, E3L.

scientific article published on December 2002

Bozepinib, a novel small antitumor agent, induces PKR-mediated apoptosis and synergizes with IFNα triggering apoptosis, autophagy and senescence

scientific article published on 29 October 2013

Cardiomyogenic differentiation potential of human endothelial progenitor cells isolated from patients with myocardial infarction

scientific article published on 23 June 2014

Caspase 9 activation by the dsRNA-dependent protein kinase, PKR: molecular mechanism and relevance.

scientific article published in October 2002

Clinical and therapeutic potential of protein kinase PKR in cancer and metabolism

scientific article

Clinical failure of nanoparticles in cancer: mimicking nature's solutions

scientific article published on 24 September 2020

Control of virus infection by tumour suppressors.

scientific article published on 7 March 2007

Enantiospecific synthesis of heterocycles linked to purines: different apoptosis modulation of enantiomers in breast cancer cells

scientific article published on January 2013

How Can Nanotechnology Help to Repair the Body? Advances in Cardiac, Skin, Bone, Cartilage and Nerve Tissue Regeneration

scientific article published on 28 March 2013

Human gene profiling in response to the active protein kinase, interferon-induced serine/threonine protein kinase (PKR), in infected cells. Involvement of the transcription factor ATF-3 IN PKR-induced apoptosis.

scientific article published on 13 April 2006

In vitro treatment of carcinoma cell lines with pancreatic (pro)enzymes suppresses the EMT programme and promotes cell differentiation

scientific article published on 16 May 2013

Involvement of PKR and RNase L in translational control and induction of apoptosis after Hepatitis C polyprotein expression from a vaccinia virus recombinant

scientific article

Low adherent cancer cell subpopulations are enriched in tumorigenic and metastatic epithelial-to-mesenchymal transition-induced cancer stem-like cells.

scientific article published on 11 January 2016

Mesenchymal stem cell's secretome promotes selective enrichment of cancer stem-like cells with specific cytogenetic profile

scientific article published on 05 May 2018

New (RS)-benzoxazepin-purines with antitumour activity: The chiral switch from (RS)-2,6-dichloro-9-[1-(p-nitrobenzenesulfonyl)-1,2,3,5-tetrahydro-4,1-benzoxazepin-3-yl]-9H-purine.

scientific article published on 3 December 2010

Pancreatic (pro)enzymes treatment suppresses BXPC-3 pancreatic Cancer Stem Cell subpopulation and impairs tumour engrafting

scientific article published on 06 August 2019

Polymers, scaffolds and bioactive molecules with therapeutic properties in osteochondral pathologies: what's new?

scientific article published on 24 June 2016

Resistance to viral infection of super p53 mice.

scientific article published in April 2005

SIRT1 stabilizes PML promoting its sumoylation

scientific article

Synthesis and anticancer activity of (RS)-9-(2,3-dihydro-1,4-benzoxaheteroin-2-ylmethyl)-9H-purines.

scientific article published on 26 May 2011

Synthesis and anticancer activity of the (R,S)-benzofused 1,5-oxathiepine moiety tethered to purines through alkylidenoxy linkers.

scientific article

The catalytic activity of dsRNA-dependent protein kinase, PKR, is required for NF-kappaB activation.

scientific article published in January 2001

The chemotherapeutic drug 5-fluorouracil promotes PKR-mediated apoptosis in a p53-independent manner in colon and breast cancer cells

scientific article

The dsRNA protein kinase PKR: virus and cell control

scientific article

The impact of PKR activation: from neurodegeneration to cancer.

scientific article published on 12 February 2014

Uncovering Tumour Heterogeneity through PKR and nc886 Analysis in Metastatic Colon Cancer Patients Treated with 5-FU-Based Chemotherapy

scientific article published on 07 February 2020

Validation of suitable normalizers for miR expression patterns analysis covering tumour heterogeneity.

scientific article published on 04 January 2017

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