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List of works by Roger E Koeppe

5-A Fourier map of gramicidin A phased by deuterium-hydrogen solvent difference neutron diffraction.

scientific article

A Combined Experimental and Theoretical Study of Ion Solvation in Liquid N-Methylacetamide ⬇️

scientific article published on August 11, 2010

A dipolar amino acid substitution induces voltage-dependent transitions between two stable conductance states in gramicidin channels ⬇️

scientific article published on April 1, 1992

A general mechanism for drug promiscuity: Studies with amiodarone and other antiarrhythmics

scientific article

A pulsed diffusion technique for the growth of protein crystals for x-ray diffraction

scientific article published on October 15, 1975

Accommodation of a Central Arginine in a Transmembrane Peptide by Changing the Placement of Anchor Residues ⬇️

scientific article published on October 17, 2012

Amino acid substitutions and ion channel function. Model-dependent conclusions ⬇️

scientific article published on April 1, 1992

Amphiphile regulation of ion channel function by changes in the bilayer spring constant.

scientific article

Are biosensor arrays in one membrane possible? A combination of multifrequency impedance measurements and chemometrics.

scientific article

Asymmetric gramicidin channels: heterodimeric channels with a single F6Val1 residue ⬇️

scientific article published on June 1, 1994

Bilayer thickness and membrane protein function: an energetic perspective.

scientific article published on January 2007

Bilayer-dependent inhibition of mechanosensitive channels by neuroactive peptide enantiomers.

scientific article

Breaking the Backbone: Central Arginine Residues Induce Membrane Exit and Helix Distortions within a Dynamic Membrane Peptide

scientific article published on 17 September 2019

Buried lysine, but not arginine, titrates and alters transmembrane helix tilt.

scientific article

Capsaicin regulates voltage-dependent sodium channels by altering lipid bilayer elasticity.

scientific article published on 20 June 2005

Characterizing Residue-Bilayer Interactions Using Gramicidin A as a Scaffold and Tryptophan Substitutions as Probes

scientific article published on 4 September 2017

Charged or aromatic anchor residue dependence of transmembrane peptide tilt.

scientific article

Closed state of gramicidin channel detected by X-ray in-plane scattering

scientific article published on 01 February 1994

Combined experimental/theoretical refinement of indole ring geometry using deuterium magnetic resonance and ab initio calculations.

scientific article published in October 2003

Comparison of "Polarization inversion with spin exchange at magic angle" and "geometric analysis of labeled alanines" methods for transmembrane helix alignment.

scientific article published on 3 September 2008

Comparisons of interfacial Phe, Tyr, and Trp residues as determinants of orientation and dynamics for GWALP transmembrane peptides.

scientific article

Concerning tryptophan and protein-bilayer interactions

scientific article published on 16 July 2007

Conformation of the acylation site of palmitoylgramicidin in lipid bilayers of dimyristoylphosphatidylcholine.

scientific article published on March 1996

Control of Transmembrane Helix Dynamics by Interfacial Tryptophan Residues

scientific article published on 01 June 2018

Curcumin is a modulator of bilayer material properties

scientific article published on 17 August 2007

Desformylgramicidin: a model channel with an extremely high water permeability.

scientific article published on November 2000

Design and characterization of gramicidin channels

scientific article published on 01 January 1999

Different Membrane Anchoring Positions of Tryptophan and Lysine in Synthetic Transmembrane α-Helical Peptides

scientific article published in Journal of Biological Chemistry

Dimer versus tetramer ⬇️

scientific article published on February 1, 1992

Docosahexaenoic acid alters bilayer elastic properties.

scholarly article

Dynamic regulation of lipid-protein interactions

scientific article

Effect of fatty acids on gluconeogenesis in the rat ⬇️

scientific article published on October 27, 1970

Effect of salt and membrane fluidity on fluorophore motions of a gramicidin C derivative

scientific article published on 01 August 1991

Effect of thiamine deficiency, pyrithiamine and oxythiamine on pyruvate metabolism in rat liver and brain in vivo

scientific article published on January 1, 1977

Effects of green tea catechins on gramicidin channel function and inferred changes in bilayer properties.

scientific article

Electrospray ionization mass spectrometry as a tool to analyze hydrogen/deuterium exchange kinetics of transmembrane peptides in lipid bilayers.

scholarly article

Energetics of gramicidin hybrid channel formation as a test for structural equivalence. Side-chain substitutions in the native sequence.

scientific article published in January 1990

Energetics of heterodimer formation among gramicidin analogues with an NH2-terminal addition or deletion. Consequences of missing a residue at the join in the channel

scientific article published on 01 June 1993

Equilibrium binding constants for the group I metal cations with gramicidin-A determined by competition studies and T1+-205 nuclear magnetic resonance spectroscopy

scientific article

Exchange of Gramicidin between Lipid Bilayers: Implications for the Mechanism of Channel Formation.

scientific article

Formation of non-beta 6.3-helical gramicidin channels between sequence-substituted gramicidin analogues.

scientific article

Genistein Can Modulate Channel Function by a Phosphorylation-Independent Mechanism: Importance of Hydrophobic Mismatch and Bilayer Mechanics ⬇️

scientific article published on November 25, 2003

Gramicidin A Backbone and Side Chain Dynamics Evaluated by Molecular Dynamics Simulations and Nuclear Magnetic Resonance Experiments. I: Molecular Dynamics Simulations ⬇️

scientific article published on May 16, 2011

Gramicidin A backbone and side chain dynamics evaluated by molecular dynamics simulations and nuclear magnetic resonance experiments. II: nuclear magnetic resonance experiments

scientific article published on 16 May 2011

Gramicidin A crystals contain two cation binding sites per channel ⬇️

scientific article published on June 21, 1979

Gramicidin channel controversy--the structure in a lipid environment

scientific article published on 01 July 1999

Gramicidin channel function does not depend on phospholipid chirality

scientific article published on 01 December 1995

Gramicidin channels in phospholipid bilayers with unsaturated acyl chains ⬇️

scientific article published on September 1, 1997

Gramicidin single-channel properties show no solvent-history dependence ⬇️

scientific article published on March 1, 1990

Gramicidins A, B, and C form structurally equivalent ion channels.

scientific article

Helix formation and stability in membranes

scientific article published on 12 February 2018

Hydrophobic coupling of lipid bilayer energetics to channel function.

scientific article published on May 2003

Hydrophobic mismatch between helices and lipid bilayers.

scientific article

Impact of the INBRE summer student mentored research program on undergraduate students in Arkansas.

scientific article published in March 2018

Importance of indole N-H hydrogen bonding in the organization and dynamics of gramicidin channels.

scientific article

Incorporation of label from [1-14C]ethanol into the glutamate–glutamine pools of rat brain in vivo ⬇️

scientific article published on February 1, 1972

Induction of conductance heterogeneity in gramicidin channels

scientific article published on 01 August 1989

Influence of High pH and Cholesterol on Single Arginine-Containing Transmembrane Peptide Helices.

scientific article published on 26 October 2016

Influence of Lipid Saturation, Hydrophobic Length and Cholesterol on Double-Arginine-Containing Helical Peptides in Bilayer Membranes

scientific article published on 18 September 2019

Influence of glutamic acid residues and pH on the properties of transmembrane helices

scientific article published on 6 January 2017

Influence of membrane-spanning alpha-helical peptides on the phase behavior of the dioleoylphosphatidylcholine/water system ⬇️

scientific article published on December 1, 1997

Influence of proline upon the folding and geometry of the WALP19 transmembrane peptide

scientific article published in December 2009

Interactions of drugs and amphiphiles with membranes: modulation of lipid bilayer elastic properties by changes in acyl chain unsaturation and protonation.

scientific article published on January 2013

Interfacial anchor properties of tryptophan residues in transmembrane peptides can dominate over hydrophobic matching effects in peptide-lipid interactions

scientific article published in May 2003

Investigation of the interaction between thallous ions and gramicidin A in dimyristoylphosphatidylcholine vesicles: a thallium-205 NMR equilibrium study

scientific article published on 01 October 1986

Ion channels as tools to monitor lipid bilayer-membrane protein interactions: gramicidin channels as molecular force transducers

scientific article published on 01 January 1999

Ion-induced defect permeation of lipid membranes

scientific article published on February 2014

Ionization Properties of Histidine Residues in the Lipid Bilayer Membrane Environment

scientific article

Is there a preferential interaction between cholesterol and tryptophan residues in membrane proteins?

scientific article

Juxta-terminal Helix Unwinding as a Stabilizing Factor to Modulate the Dynamics of Transmembrane Helices.

scientific article published on 8 January 2016

Kinetics of Gramicidin Channel Formation in Lipid Bilayers: Transmembrane Monomer Association ⬇️

scientific article published on November 30, 1990

L(+) and D(-0 lactate as precursors of muscle glycogen ⬇️

scientific article published on 01 July 1965

Lipid bilayer thickness determines cholesterol's location in model membranes

scientific article published on November 2016

Mannose-6-P and mannose-1-P in rat brain, kidney and liver ⬇️

scientific article published on July 12, 1979

Mechanism of hydrolysis by serine proteases: direct determination of the pKa's of aspartyl-102 and aspartyl-194 in bovine trypsin using difference infrared spectroscopy

scientific article published on 01 August 1976

Membrane Bending Moduli of Coexisting Liquid Phases Containing Transmembrane Peptide

scientific article published on 01 May 2018

Membrane Bending Moduli of Coexisting Liquid Phases Containing Transmembrane Peptide

scientific article published on 01 July 2018

Membrane Organization and Dynamics of “Inner Pair” and “Outer Pair” Tryptophan Residues in Gramicidin Channels ⬇️

scientific article published on August 30, 2012

Models for gramicidin channels ⬇️

scientific article published on March 1, 1992

Modulation of Gramicidin Channel Structure and Function by the Aliphatic “Spacer” Residues 10, 12, and 14 between the Tryptophans†

scientific article published on 01 January 1999

Molecular and channel-forming characteristics of gramicidin K's: a family of naturally occurring acylated gramicidins

scientific article published on 01 August 1992

Multivariate data analysis for enhanced interpretation of electrochemical impedance spectra of gramicidin-ion interactions in phospholipid monolayers.

scientific article

Neighboring Aliphatic/Aromatic Side Chain Interactions between Residues 9 and 10 in Gramicidin Channels†

scientific article published on 01 March 2000

On the combined analysis of ²H and ¹⁵N/¹H solid-state NMR data for determination of transmembrane peptide orientation and dynamics

scientific article

Orientation and motion of tryptophan interfacial anchors in membrane-spanning peptides.

scientific article published on 27 May 2007

Orientation of the valine-1 side chain of the gramicidin transmembrane channel and implications for channel functioning. A 2H NMR study

scientific article published on 01 November 1992

PYRUVATE DECARBOXYLATION IN THIAMINE DEFICIENT BRAIN ⬇️

scientific article published in September 1964

Palmitoylation-Induced Conformational Changes of Specific Side Chains in the Gramicidin Transmembrane Channel

scientific article published on 01 July 1995

Pathway of Ethanol Metabolism in the Rat

scientific article

Phosphoinositides alter lipid bilayer properties.

scientific article published on June 2013

Polar groups in membrane channels: consequences of replacing alanines with serines in membrane-spanning gramicidin channels.

scientific article published on August 2010

Precursors in vivo of glutamate, aspartate and their derivatives of rat brain ⬇️

scientific article

Proline kink angle distributions for GWALP23 in lipid bilayers of different thicknesses.

scientific article published on 18 April 2012

Response of GWALP Transmembrane Peptides to Changes in the Tryptophan Anchor Positions ⬇️

scientific article published on August 12, 2011

Role of lysine-195 in the KMSKS sequence of E. coli tryptophanyl-tRNA synthetase.

scientific article

Role of the TIGN sequence in E. coli tryptophanyl-tRNA synthetase.

scientific article

Sensitivity of single membrane-spanning alpha-helical peptides to hydrophobic mismatch with a lipid bilayer: effects on backbone structure, orientation, and extent of membrane incorporation.

scientific article published in April 2001

Single tryptophan and tyrosine comparisons in the N-terminal and C-terminal interface regions of transmembrane GWALP peptides

scientific article

Single-channel studies on linear gramicidins with altered amino acid sequences. A comparison of phenylalanine, tryptophane, and tyrosine substitutions at positions 1 and 11 ⬇️

scientific article published on January 1, 1984

Single-channel studies on linear gramicidins with altered amino acid side chains. Effects of altering the polarity of the side chain at position 1 in gramicidin A

scientific article

Stabilizing effect of D-alanine2 in gramicidin channels

scientific article published on 01 May 1995

Steric interactions of valines 1, 5, and 7 in [valine 5, D-alanine 8] gramicidin A channels.

scientific article

Stimulation of cation transport in mitochondria by gramicidin and truncated derivatives

scientific article published on 01 May 1989

Studies on rat brain acyl-coenzyme A hydrolase (short chain)

scientific article published on August 23, 1976

TI-205 nuclear magnetic resonance determination of the thermodynamic parameters for the binding of monovalent cations to gramicidins A and C

scientific article

The Membrane Interface Dictates Different Anchor Roles for “Inner Pair” and “Outer Pair” Tryptophan Indole Rings in Gramicidin A Channels ⬇️

scientific article published on May 13, 2011

The effect of fasting and several hyperglycaemic agents on the free amino acids of rat liver ⬇️

scientific article published on September 22, 1970

The effect of pre-incubation on trypsin kinetics at low pH ⬇️

scientific article published on April 12, 1977

The spectral sensitivity of retinal photoreceptors conducting the pupillary light reflex in humans ⬇️

scientific article published on 01 January 1969

The toxicity of monosodium glutamate in young rats ⬇️

scientific article published on August 19, 1971

Tilt angles of transmembrane model peptides in oriented and non-oriented lipid bilayers as determined by 2H solid-state NMR.

scientific article

Transmembrane Helix Integrity versus Fraying To Expose Hydrogen Bonds at a Membrane-Water Interface

scientific article published on 03 January 2019

Tryptophan-Anchored Transmembrane Peptides Promote Formation of Nonlamellar Phases in Phosphatidylethanolamine Model Membranes in a Mismatch-Dependent Manner†

article

Tyrosine replacing tryptophan as an anchor in GWALP peptides.

scientific article published on 5 March 2012

Variation of neurotoxicity of l- and d-2,4-diaminobutyric acid with route of administration ⬇️

scientific article published on October 1, 1972

Wavelength-Selective Fluorescence of a Model Transmembrane Peptide: Constrained Dynamics of Interfacial Tryptophan Anchors

scientific article published on 17 September 2018

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