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List of works by Angela Wandinger-Ness

A Novel Pharmacologic Activity of Ketorolac for Therapeutic Benefit in Ovarian Cancer Patients

scientific article

A Pan-GTPase Inhibitor as a Molecular Probe

scientific article

A Potent and Selective Inhibitor of Cdc42 GTPase

A competitive nucleotide binding inhibitor: in vitro characterization of Rab7 GTPase inhibition

scientific article

A conserved signal and GTPase complex are required for the ciliary transport of polycystin-1.

scientific article

A polycystin multiprotein complex constitutes a cholesterol-containing signalling microdomain in human kidney epithelia.

scientific article

A polycystin-1 multiprotein complex is disrupted in polycystic kidney disease cells

scientific article published on 12 January 2004

A small molecule pan-inhibitor of Ras-superfamily GTPases with high efficacy towards Rab7

A telomerase immortalized human proximal tubule cell line with a truncation mutation (Q4004X) in polycystin-1

scientific article

Activation of Rho Family GTPases by Small Molecules.

scientific article

Adult human CD133/1(+) kidney cells isolated from papilla integrate into developing kidney tubules

scientific article

Altered trafficking and epithelial cell polarity in disease

scientific article

Attenuated, flow-induced ATP release contributes to absence of flow-sensitive, purinergic Cai2+ signaling in human ADPKD cyst epithelial cells

scientific article published on 25 February 2009

Bacterial pathogens commandeer Rab GTPases to establish intracellular niches

scientific article

Caveolin-1-dependent infectious entry of human papillomavirus type 31 in human keratinocytes proceeds to the endosomal pathway for pH-dependent uncoating

scientific article published on 30 July 2008

Characterization of a Cdc42 protein inhibitor and its use as a molecular probe

scientific article published on 4 February 2013

Characterization of a Cdc42 protein inhibitor and its use as a molecular probe.

scientific article published in March 2014

Clustering and redistribution of late endocytic compartments in response to Helicobacter pylori vacuolating toxin

scientific article published on 23 January 2004

Constrained inference of protein interaction networks for invadopodium formation in cancer

scientific article

Differential downregulation of e-cadherin and desmoglein by epidermal growth factor.

scientific article published on 16 January 2012

Drug Repurposing from an Academic Perspective

scientific article published on January 2011

Dual Actions of Ketorolac in Metastatic Ovarian Cancer

scientific article published on 24 July 2019

Dual-Purpose Bioreactors to Monitor Noninvasive Physical and Biochemical Markers of Kidney and Liver Scaffold Recellularization

scientific article

Ectopic expression of cadherin 8 is sufficient to cause cyst formation in a novel 3D collagen matrix renal tubule culture ⬇️

scientific article published on March 9, 2011

Epithelial Cell Repopulation and Preparation of Rodent Extracellular Matrix Scaffolds for Renal Tissue Development

scientific article

Flow cytometry for real-time measurement of guanine nucleotide binding and exchange by Ras-like GTPases

scientific article published on 08 July 2008

Functional analyses and interaction of the XAPC7 proteasome subunit with Rab7.

scientific article published on January 2005

Glutathione-S-transferase-green fluorescent protein fusion protein reveals slow dissociation from high site density beads and measures free GSH.

scientific article published in May 2006

Human ADPKD primary cyst epithelial cells with a novel, single codon deletion in the PKD1 gene exhibit defective ciliary polycystin localization and loss of flow-induced Ca2+ signaling.

scientific article published on 7 November 2006

Human VPS34 and p150 are Rab7 Interacting Partners ⬇️

scientific article published on November 1, 2003

Identification of a small GTPase inhibitor using a high-throughput flow cytometry bead-based multiplex assay

scientific article

Interaction and functional analyses of human VPS34/p150 phosphatidylinositol 3-kinase complex with Rab7.

scientific article published on January 2005

Meeting report - Arf and Rab family G proteins

scientific article published in December 2013

Mispolarization of desmosomal proteins and altered intercellular adhesion in autosomal dominant polycystic kidney disease

scientific article published on 8 February 2005

Myotubularin lipid phosphatase binds the hVPS15/hVPS34 lipid kinase complex on endosomes

scientific article

Novel Activities of Select NSAID R-Enantiomers against Rac1 and Cdc42 GTPases

scientific article

OFD1 and flotillins are integral components of a ciliary signaling protein complex organized by polycystins in renal epithelia and odontoblasts

scientific article

Ovarian Tumor Microenvironment Signaling: Convergence on the Rac1 GTPase

scientific article published on 27 September 2018

Phosphoinositide-regulated retrograde transport of ricin: crosstalk between hVps34 and sorting nexins

scientific article

Progesterone receptor isoform identification and subcellular localization in endometrial cancer

scientific article published on January 2005

Quantitative bead-based flow cytometry for assaying Rab7 GTPase interaction with the Rab-interacting lysosomal protein (RILP) effector protein

scientific article published in January 2015

R-Ketorolac Targets Cdc42 and Rac1 and Alters Ovarian Cancer Cell Behaviors Critical for Invasion and Metastasis

scientific article

RAS (H-, K-, N-RAS)

article

ROCK Kinases

article

Rab GTPases at a glance

scientific article published on 01 November 2007

Rab proteins and endocytic trafficking: potential targets for therapeutic intervention ⬇️

scientific article published on November 14, 2003

Rab proteins and the compartmentalization of the endosomal system

scientific article published on 23 October 2014

Rab7 Mutants Associated with Charcot-Marie-Tooth Disease Cause Delayed Growth Factor Receptor Transport and Altered Endosomal and Nuclear Signaling ⬇️

scientific article published on November 27, 2012

Rab7 mutants associated with Charcot-Marie-Tooth disease exhibit enhanced NGF-stimulated signaling

scientific article

Rapid parallel flow cytometry assays of active GTPases using effector beads

scientific article published on 06 August 2013

Receptor protein tyrosine phosphatases are novel components of a polycystin complex ⬇️

scientific article published on November 29, 2010

Sequential actions of myotubularin lipid phosphatases regulate endosomal PI(3)P and growth factor receptor trafficking

scientific article published on 4 June 2008

Small-Volume Flow Cytometry-Based Multiplex Analysis of the Activity of Small GTPases

scientific article published on 01 January 2018

The R-enantiomer of ketorolac delays mammary tumor development in mouse mammary tumor virus-polyoma middle T antigen (MMTV-PyMT) mice.

scientific article published on 20 November 2017

The R-enantiomer of ketorolac reduces ovarian cancer tumor burden in vivo

scientific article published on 07 January 2021

The proteasome alpha-subunit XAPC7 interacts specifically with Rab7 and late endosomes

scientific article published on 2 March 2004

Three small molecule pan activator families of Ras-related GTPases

Transcriptome analysis reveals manifold mechanisms of cyst development in ADPKD.

scientific article

Vesicular trafficking of tyrosine kinase receptors and associated proteins in the regulation of signaling and vascular function

scientific article

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