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List of works by Nathaniel Weygant

(Z)-3,5,4'-Trimethoxystilbene Limits Hepatitis C and Cancer Pathophysiology by Blocking Microtubule Dynamics and Cell-Cycle Progression.

scientific article published on 10 June 2016

Ablation of Doublecortin-Like Kinase 1 in the Colonic Epithelium Exacerbates Dextran Sulfate Sodium-Induced Colitis

scientific article published on 18 August 2015

Advances in Tumor-Stroma Interactions: Emerging Role of Cytokine Network in Colorectal and Pancreatic Cancer.

scientific article published on 5 May 2019

Alternative splice variants of DCLK1 mark cancer stem cells, promote self-renewal and drug-resistance, and can be targeted to inhibit tumorigenesis in kidney cancer.

scientific article

Brief report: Dclk1 deletion in tuft cells results in impaired epithelial repair after radiation injury.

scientific article

Cancer Stem Cell Marker DCLK1 Correlates with Tumorigenic Immune Infiltrates in the Colon and Gastric Adenocarcinoma Microenvironments

scientific article published on 22 January 2020

Circadian clock genes promote glioma progression by affecting tumour immune infiltration and tumour cell proliferation

scientific article published on 13 January 2021

Correction: Fluvastatin Interferes with Hepatitis C Virus Replication via Microtubule Bundling and a Doublecortin-like Kinase-Mediated Mechanism

DCLK1 facilitates intestinal tumor growth via enhancing pluripotency and epithelial mesenchymal transition

scientific article

DCLK1 is a broadly dysregulated target against epithelial-mesenchymal transition, focal adhesion, and stemness in clear cell renal carcinoma

scientific article

DCLK1 regulates pluripotency and angiogenic factors via microRNA-dependent mechanisms in pancreatic cancer

scientific article

DCLK1-isoform2 alternative splice variant promotes pancreatic tumor immunosuppressive M2-macrophage polarization

scientific article published on 05 May 2020

Dclk1+ small intestinal epithelial tuft cells display the hallmarks of quiescence and self-renewal

scientific article published on 2 September 2015

Dclk1, a tumor stem cell marker, regulates pro-survival signaling and self-renewal of intestinal tumor cells.

scientific article published on February 2017

Dietary Pectin Increases Intestinal Crypt Stem Cell Survival following Radiation Injury

scientific article (publication date: 2015)

Doublecortin-like kinase 1 is elevated serologically in pancreatic ductal adenocarcinoma and widely expressed on circulating tumor cells

scientific article

Epigenetic Influences in the Obesity/Colorectal Cancer Axis: A Novel Theragnostic Avenue

scientific article published on 17 March 2019

Fluvastatin interferes with hepatitis C virus replication via microtubule bundling and a doublecortin-like kinase-mediated mechanism

scientific article

Identification of Transcriptional Signatures of Colon Tumor Stroma by a Meta-Analysis

scientific article published on 02 May 2019

Identification of the putative intestinal stem cell marker doublecortin and CaM kinase-like-1 in Barrett's esophagus and esophageal adenocarcinoma.

scientific article published on April 2012

Implications for Tumor Microenvironment and Epithelial Crosstalk in the Management of Gastrointestinal Cancers

scientific article published on 31 October 2019

Inflammatory and oncogenic roles of a tumor stem cell marker doublecortin-like kinase (DCLK1) in virus-induced chronic liver diseases

scientific article

Inhibition of Notch signaling reduces the number of surviving Dclk1+ reserve crypt epithelial stem cells following radiation injury.

scientific article published on 24 December 2013

Intestinal tuft cells regulate the ATM mediated DNA Damage response via Dclk1 dependent mechanism for crypt restitution following radiation injury.

scientific article

Overexpression of DCLK1-AL Increases Tumor Cell Invasion, Drug Resistance, and KRAS Activation and Can Be Targeted to Inhibit Tumorigenesis in Pancreatic Cancer

scientific article published on 05 August 2019

Plasma DCLK1 is a marker of hepatocellular carcinoma (HCC): Targeting DCLK1 prevents HCC tumor xenograft growth via a microRNA-dependent mechanism.

scientific article

Qingda granule exerts neuroprotective effects against ischemia/reperfusion-induced cerebral injury via lncRNA GAS5/miR-137 signaling pathway

scientific article published on 06 February 2021

RAS/BRAF Circulating Tumor DNA Mutations as a Predictor of Response to First-Line Chemotherapy in Metastatic Colorectal Cancer Patients.

scientific article published on 7 March 2018

Regulatory Roles of Dclk1 in Epithelial Mesenchymal Transition and Cancer Stem Cells

scientific article published on 07 March 2016

Role of the Microenvironment in Gastrointestinal Tumors

scientific article published on 11 December 2019

Small molecule kinase inhibitor LRRK2-IN-1 demonstrates potent activity against colorectal and pancreatic cancer through inhibition of doublecortin-like kinase 1.

scientific article

Survival of Patients with Gastrointestinal Cancers Can Be Predicted by a Surrogate microRNA Signature for Cancer Stem-like Cells Marked by DCLK1 Kinase.

scientific article published on 10 June 2016

Tuft and Cancer Stem Cell Marker DCLK1: A New Target to Enhance Anti-Tumor Immunity in the Tumor Microenvironment

scientific article published on 17 December 2020

Tuft cells: an emerging therapeutic target for pancreatitis and pancreatic cancer?

scientific article published on 12 November 2020

XMD8-92 inhibits pancreatic tumor xenograft growth via a DCLK1-dependent mechanism.

scientific article

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