List of works - Mikio Furuse

1H, 13C, and 15N resonance assignment of the first PDZ domain of mouse ZO-1 ⬇️

scientific article published on March 24, 2011

A "Tric" to tighten cell-cell junctions in the cochlea for hearing

scientific article published on 27 August 2013

A coronary artery disease-associated gene product, JCAD/KIAA1462, is a novel component of endothelial cell-cell junctions

scientific journal article

A novel protein complex, Mesh-Ssk, is required for septate junction formation in the Drosophila midgut.

scientific article published in August 2012

Altered expression of tight junction molecules in alveolar septa in lung injury and fibrosis.

scientific article published on 14 October 2011

Analysis of the 'angulin' proteins LSR, ILDR1 and ILDR2--tricellulin recruitment, epithelial barrier function and implication in deafness pathogenesis.

scientific article published on 13 December 2012

CD44 regulates tight-junction assembly and barrier function

scientific article published on 30 December 2010

Ca(2+)-independent cell-adhesion activity of claudins, a family of integral membrane proteins localized at tight junctions

scientific article

Characteristics of claudin expression in follicle-associated epithelium of Peyer's patches: preferential localization of claudin-4 at the apex of the dome region.

scientific article

Claudin multigene family encoding four-transmembrane domain protein components of tight junction strands

scientific article

Claudin-1 and -2: novel integral membrane proteins localizing at tight junctions with no sequence similarity to occludin

scientific article

Claudin-2 knockout by TALEN-mediated gene targeting in MDCK cells: claudin-2 independently determines the leaky property of tight junctions in MDCK cells.

scientific article

Claudin-2 regulates colorectal inflammation via myosin light chain kinase-dependent signaling.

scientific article published on 11 January 2013

Claudin-4 induction by E-protein activity in later stages of CD4/8 double-positive thymocytes to increase positive selection efficiency

scientific article

Claudin-4 knockout by TALEN-mediated gene targeting in MDCK cells: Claudin-4 is dispensable for the permeability properties of tight junctions in wild-type MDCK cells

scientific article

Claudin-5 haploinsufficiency exacerbates UVB-induced oedema formation by inducing lymphatic vessel leakage

scientific article published on 01 July 2012

Claudin-based barrier in simple and stratified cellular sheets

scientific article (publication date: October 2002)

Claudins and JAM-A coordinately regulate tight junction formation and epithelial polarity

scientific article published on 29 August 2019

Claudins and renal salt transport ⬇️

scientific article published on November 1, 2011

Clostridium perfringens enterotoxin binds to the second extracellular loop of claudin-3, a tight junction integral membrane protein

scientific article (publication date: 7 July 2000)

Clostridium perfringens enterotoxin fragment removes specific claudins from tight junction strands: Evidence for direct involvement of claudins in tight junction barrier.

scientific article published on October 1999

Complex phenotype of mice lacking occludin, a component of tight junction strands.

scientific article

Contribution of tight junction proteins to ion, macromolecule, and water barrier in keratinocytes

scientific article

Deafness in occludin-deficient mice with dislocation of tricellulin and progressive apoptosis of the hair cells

scientific article

Deficiency of angulin-2/ILDR1, a tricellular tight junction-associated membrane protein, causes deafness with cochlear hair cell degeneration in mice

scientific journal article

Direct association of occludin with ZO-1 and its possible involvement in the localization of occludin at tight junctions

scientific article

Downsloping high-frequency hearing loss due to inner ear tricellular tight junction disruption by a novel ILDR1 mutation in the Ig-like domain

scientific article

Effects of Hydrostatic Pressure on Carcinogenic Properties of Epithelia

scientific article

Effects of Osmolality on Paracellular Transport in MDCK II Cells.

scientific article

Endothelial claudin: claudin-5/TMVCF constitutes tight junction strands in endothelial cells

scientific article

Epidermal cell turnover across tight junctions based on Kelvin's tetrakaidecahedron cell shape

scientific article

Epidermal tight junction barrier function is altered by skin inflammation, but not by filaggrin-deficient stratum corneum

scientific article published on 22 November 2014

Expression and distribution of ZO‐3, a tight junction MAGUK protein, in mouse tissues ⬇️

scientific article published on November 1, 2003

Expression patterns of claudin family of tight junction membrane proteins in developing mouse submandibular gland.

scientific article published in October 2004

Expression patterns of claudins, tight junction adhesion molecules, in the inner ear

scientific article (publication date: 2004)

Flightless-I (Fli-I) regulates the actin assembly activity of diaphanous-related formins (DRFs) Daam1 and mDia1 in cooperation with active Rho GTPase.

scientific article published on 11 March 2010

Generation of transgenic medaka expressing claudin7-EGFP for imaging of tight junctions in living medaka embryos.

scientific article published on 27 November 2008

Identification of adherens junction-associated GTPase activating proteins by the fluorescence localization-based expression cloning.

scientific article

In vivo imaging of tight junctions using claudin-EGFP transgenic medaka.

scientific article published in January 2011

Induction of strong homotypic adhesion in human T cell lines positive with human T-cell leukemia virus type 1 by monoclonal antibodies to MHC class I and beta 2-microglobulin

scientific article published on September 1, 1992

Interspecies diversity of the occludin sequence: cDNA cloning of human, mouse, dog, and rat-kangaroo homologues

scientific article

JNK1/2-dependent phosphorylation of angulin-1/LSR is required for the exclusive localization of angulin-1/LSR and tricellulin at tricellular contacts in EpH4 epithelial sheet

scientific journal article

Lipolysis-stimulated lipoprotein receptor: a novel membrane protein of tricellular tight junctions

scientific journal article

Localization of angulin-1/LSR and tricellulin at tricellular contacts of brain and retinal endothelial cells in vivo.

scientific article

Loss of occludin affects tricellular localization of tricellulin.

scientific article published on 3 September 2008

Megaintestine in claudin-15-deficient mice

scientific article published on 28 November 2007

Molecular dissection of smooth septate junctions: understanding their roles in arthropod physiology.

scientific article

Molecular organization and function of invertebrate occluding junctions

scientific article

Molecular organization of tricellular tight junctions

scientific article

Multi-PDZ Domain Protein 1 (MUPP1) Is Concentrated at Tight Junctions through Its Possible Interaction with Claudin-1 and Junctional Adhesion Molecule ⬇️

scientific article (publication date: 4 January 2002)

Multifunctional strands in tight junctions

scientific article (publication date: April 2001)

Occludin-deficient Embryonic Stem Cells Can Differentiate into Polarized Epithelial Cells Bearing Tight Junctions ⬇️

scientific article published on April 20, 1998

Occludin: a novel integral membrane protein localizing at tight junctions

scientific article

Overcoming barriers in the study of tight junction functions: from occludin to claudin

scientific article published on 01 September 1998

Phosphorylation state regulates the localization of Scribble at adherens junctions and its association with E-cadherin-catenin complexes

scientific article published on 10 December 2010

Promotion of lymphatic integrity by angiopoietin-1/Tie2 signaling during inflammation.

scientific article

Requirement of ZO-1 for the formation of belt-like adherens junctions during epithelial cell polarization

scientific article

Ripply3 is required for the maintenance of epithelial sheets in the morphogenesis of pharyngeal pouches

scientific article published on 22 February 2018

Similar and distinct properties of MUPP1 and Patj, two homologous PDZ domain-containing tight-junction proteins.

scientific article

Strong induction of ICAM-1 in human T cells transformed by human T-cell-leukemia virus type 1 and depression of ICAM-1 or LFA-1 in adult T-cell-leukemia-derived cell lines

scientific article published on September 30, 1992

Subcellular distribution of tight junction-associated proteins (occludin, ZO-1, ZO-2) in rodent skin.

scientific article published in June 1998

Targeted Disruption of JCAD (Junctional Protein Associated With Coronary Artery Disease)/KIAA1462, a Coronary Artery Disease-Associated Gene Product, Inhibits Angiogenic Processes In Vitro and In Vivo

scientific article published on 13 July 2017

The Drosophila Claudin Kune-kune is required for septate junction organization and tracheal tube size control.

scientific article

The E3 ubiquitin ligase LNX1p80 promotes the removal of claudins from tight junctions in MDCK cells.

scientific article published on April 2009

The extracellular domain of angulin-1 and palmitoylation of its cytoplasmic region are required for angulin-1 assembly at tricellular contacts

scientific article published on 20 February 2020

The role of claudin-based tight junctions in morphogenesis.

scientific article published in May 2009

Tight junction dysfunction in the stratum granulosum leads to aberrant stratum corneum barrier function in claudin-1-deficient mice.

scientific article published on 31 January 2013

Tight junctions containing claudin 4 and 6 are essential for blastocyst formation in preimplantation mouse embryos.

scientific article published on 4 October 2007

Tight junctions in Schwann cells of peripheral myelinated axons: a lesson from claudin-19-deficient mice

scientific journal article

Tight junctions in epidermis: from barrier to keratinization

scientific article published on January 1, 2011

Tricellulin regulates junctional tension of epithelial cells at tricellular contacts through Cdc42.

scientific article published on 5 August 2014

ZO-1 knockout by TALEN-mediated gene targeting in MDCK cells: involvement of ZO-1 in the regulation of cytoskeleton and cell shape

scientific article (publication date: 2014)

[Molecular organization of tricellular tight junctions].

scientific article

List of works by Mikio Furuse

1H, 13C, and 15N resonance assignment of the first PDZ domain of mouse ZO-1 ⬇️

A "Tric" to tighten cell-cell junctions in the cochlea for hearing

A coronary artery disease-associated gene product, JCAD/KIAA1462, is a novel component of endothelial cell-cell junctions

A novel protein complex, Mesh-Ssk, is required for septate junction formation in the Drosophila midgut.

Altered expression of tight junction molecules in alveolar septa in lung injury and fibrosis.

Analysis of the 'angulin' proteins LSR, ILDR1 and ILDR2--tricellulin recruitment, epithelial barrier function and implication in deafness pathogenesis.

CD44 regulates tight-junction assembly and barrier function

Ca(2+)-independent cell-adhesion activity of claudins, a family of integral membrane proteins localized at tight junctions

Characteristics of claudin expression in follicle-associated epithelium of Peyer's patches: preferential localization of claudin-4 at the apex of the dome region.

Claudin multigene family encoding four-transmembrane domain protein components of tight junction strands

Claudin-1 and -2: novel integral membrane proteins localizing at tight junctions with no sequence similarity to occludin

Claudin-2 knockout by TALEN-mediated gene targeting in MDCK cells: claudin-2 independently determines the leaky property of tight junctions in MDCK cells.

Claudin-2 regulates colorectal inflammation via myosin light chain kinase-dependent signaling.

Claudin-4 induction by E-protein activity in later stages of CD4/8 double-positive thymocytes to increase positive selection efficiency

Claudin-4 knockout by TALEN-mediated gene targeting in MDCK cells: Claudin-4 is dispensable for the permeability properties of tight junctions in wild-type MDCK cells

Claudin-5 haploinsufficiency exacerbates UVB-induced oedema formation by inducing lymphatic vessel leakage

Claudin-based barrier in simple and stratified cellular sheets

Claudins and JAM-A coordinately regulate tight junction formation and epithelial polarity

Claudins and renal salt transport ⬇️

Clostridium perfringens enterotoxin binds to the second extracellular loop of claudin-3, a tight junction integral membrane protein

Clostridium perfringens enterotoxin fragment removes specific claudins from tight junction strands: Evidence for direct involvement of claudins in tight junction barrier.

Complex phenotype of mice lacking occludin, a component of tight junction strands.

Contribution of tight junction proteins to ion, macromolecule, and water barrier in keratinocytes

Deafness in occludin-deficient mice with dislocation of tricellulin and progressive apoptosis of the hair cells

Deficiency of angulin-2/ILDR1, a tricellular tight junction-associated membrane protein, causes deafness with cochlear hair cell degeneration in mice

Direct association of occludin with ZO-1 and its possible involvement in the localization of occludin at tight junctions

Downsloping high-frequency hearing loss due to inner ear tricellular tight junction disruption by a novel ILDR1 mutation in the Ig-like domain

Effects of Hydrostatic Pressure on Carcinogenic Properties of Epithelia

Effects of Osmolality on Paracellular Transport in MDCK II Cells.

Endothelial claudin: claudin-5/TMVCF constitutes tight junction strands in endothelial cells

Epidermal cell turnover across tight junctions based on Kelvin's tetrakaidecahedron cell shape

Epidermal tight junction barrier function is altered by skin inflammation, but not by filaggrin-deficient stratum corneum

Expression and distribution of ZO‐3, a tight junction MAGUK protein, in mouse tissues ⬇️

Expression patterns of claudin family of tight junction membrane proteins in developing mouse submandibular gland.

Expression patterns of claudins, tight junction adhesion molecules, in the inner ear

Flightless-I (Fli-I) regulates the actin assembly activity of diaphanous-related formins (DRFs) Daam1 and mDia1 in cooperation with active Rho GTPase.

Generation of transgenic medaka expressing claudin7-EGFP for imaging of tight junctions in living medaka embryos.

Identification of adherens junction-associated GTPase activating proteins by the fluorescence localization-based expression cloning.

In vivo imaging of tight junctions using claudin-EGFP transgenic medaka.

Induction of strong homotypic adhesion in human T cell lines positive with human T-cell leukemia virus type 1 by monoclonal antibodies to MHC class I and beta 2-microglobulin

Interspecies diversity of the occludin sequence: cDNA cloning of human, mouse, dog, and rat-kangaroo homologues

JNK1/2-dependent phosphorylation of angulin-1/LSR is required for the exclusive localization of angulin-1/LSR and tricellulin at tricellular contacts in EpH4 epithelial sheet

Lipolysis-stimulated lipoprotein receptor: a novel membrane protein of tricellular tight junctions

Localization of angulin-1/LSR and tricellulin at tricellular contacts of brain and retinal endothelial cells in vivo.

Loss of occludin affects tricellular localization of tricellulin.

Megaintestine in claudin-15-deficient mice

Molecular dissection of smooth septate junctions: understanding their roles in arthropod physiology.

Molecular organization and function of invertebrate occluding junctions

Molecular organization of tricellular tight junctions

Multi-PDZ Domain Protein 1 (MUPP1) Is Concentrated at Tight Junctions through Its Possible Interaction with Claudin-1 and Junctional Adhesion Molecule ⬇️

Multifunctional strands in tight junctions

Occludin-deficient Embryonic Stem Cells Can Differentiate into Polarized Epithelial Cells Bearing Tight Junctions ⬇️

Occludin: a novel integral membrane protein localizing at tight junctions

Overcoming barriers in the study of tight junction functions: from occludin to claudin

Phosphorylation state regulates the localization of Scribble at adherens junctions and its association with E-cadherin-catenin complexes

Promotion of lymphatic integrity by angiopoietin-1/Tie2 signaling during inflammation.

Requirement of ZO-1 for the formation of belt-like adherens junctions during epithelial cell polarization

Ripply3 is required for the maintenance of epithelial sheets in the morphogenesis of pharyngeal pouches

Similar and distinct properties of MUPP1 and Patj, two homologous PDZ domain-containing tight-junction proteins.

Strong induction of ICAM-1 in human T cells transformed by human T-cell-leukemia virus type 1 and depression of ICAM-1 or LFA-1 in adult T-cell-leukemia-derived cell lines

Subcellular distribution of tight junction-associated proteins (occludin, ZO-1, ZO-2) in rodent skin.

Targeted Disruption of JCAD (Junctional Protein Associated With Coronary Artery Disease)/KIAA1462, a Coronary Artery Disease-Associated Gene Product, Inhibits Angiogenic Processes In Vitro and In Vivo

The Drosophila Claudin Kune-kune is required for septate junction organization and tracheal tube size control.

The E3 ubiquitin ligase LNX1p80 promotes the removal of claudins from tight junctions in MDCK cells.

The extracellular domain of angulin-1 and palmitoylation of its cytoplasmic region are required for angulin-1 assembly at tricellular contacts

The role of claudin-based tight junctions in morphogenesis.

Tight junction dysfunction in the stratum granulosum leads to aberrant stratum corneum barrier function in claudin-1-deficient mice.

Tight junctions containing claudin 4 and 6 are essential for blastocyst formation in preimplantation mouse embryos.

Tight junctions in Schwann cells of peripheral myelinated axons: a lesson from claudin-19-deficient mice

Tight junctions in epidermis: from barrier to keratinization

Tricellulin regulates junctional tension of epithelial cells at tricellular contacts through Cdc42.

ZO-1 knockout by TALEN-mediated gene targeting in MDCK cells: involvement of ZO-1 in the regulation of cytoskeleton and cell shape

[Molecular organization of tricellular tight junctions].