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List of works by Mark Mitton-Fry

1,3-Dioxane-Linked Bacterial Topoisomerase Inhibitors with Enhanced Antibacterial Activity and Reduced hERG Inhibition

scientific article published on 09 May 2019

Biomarker-assisted dose selection for safety and efficacy in early development of PNU-100480 for tuberculosis

scientific article

Heterocyclic methylsulfone hydroxamic acid LpxC inhibitors as Gram-negative antibacterial agents

scientific article published on 24 September 2012

Identification of N-{cis-3-[Methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]cyclobutyl}propane-1-sulfonamide (PF-04965842): A Selective JAK1 Clinical Candidate for the Treatment of Autoimmune Diseases.

scientific article published on 3 January 2018

Novel 3-fluoro-6-methoxyquinoline derivatives as inhibitors of bacterial DNA gyrase and topoisomerase IV.

scientific article published on 3 June 2017

Novel monobactams utilizing a siderophore uptake mechanism for the treatment of gram-negative infections ⬇️

scientific article published on July 20, 2012

Oclacitinib (APOQUEL(®)) is a novel Janus kinase inhibitor with activity against cytokines involved in allergy.

scientific article

Pharmacokinetics and whole-blood bactericidal activity against Mycobacterium tuberculosis of single doses of PNU-100480 in healthy volunteers.

scientific article published on September 2010

Preparation, gram-negative antibacterial activity, and hydrolytic stability of novel siderophore-conjugated monocarbam diols.

scientific article published on 2 March 2011

Pyridone methylsulfone hydroxamate LpxC inhibitors for the treatment of serious gram-negative infections

scientific article

Pyridone-conjugated monobactam antibiotics with gram-negative activity

scientific article

Rapid evaluation in whole blood culture of regimens for XDR-TB containing PNU-100480 (sutezolid), TMC207, PA-824, SQ109, and pyrazinamide

scientific article

The identification of orally bioavailable thrombopoietin agonists.

scientific article published on 15 January 2009

The total synthesis of the oxopolyene macrolide RK-397

scientific article published on 01 January 2007

Total synthesis of dermostatin A

scientific article published on 15 September 2011

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