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List of works by Michael A Cousin

A (free) radical approach reveals the physiological function of different synaptic vesicle pools.

scientific article published in February 2017

A Fine Balance of Synaptophysin Levels Underlies Efficient Retrieval of Synaptobrevin II to Synaptic Vesicles

scientific article published on 12 February 2016

A Syntenic Cross Species Aneuploidy Genetic Screen Links RCAN1 Expression to β-Cell Mitochondrial Dysfunction in Type 2 Diabetes

scientific article

A molecular toggle after exocytosis sequesters the presynaptic syntaxin1a molecules involved in prior vesicle fusion ⬇️

scientific article

A novel mouse model of Warburg Micro syndrome reveals roles for RAB18 in eye development and organisation of the neuronal cytoskeleton

scientific article

Activation of silent and weak synapses by cAMP-dependent protein kinase in cultured cerebellar granule neurons.

scientific article published on 21 February 2011

Activity-dependent bulk endocytosis and clathrin-dependent endocytosis replenish specific synaptic vesicle pools in central nerve terminals

scientific article

Activity-dependent bulk endocytosis proteome reveals a key presynaptic role for the monomeric GTPase Rab11

article published in the Proceedings of the National Academy of Sciences of the United States of America

Adaptor Protein Complexes 1 and 3 Are Essential for Generation of Synaptic Vesicles from Activity-Dependent Bulk Endosomes ⬇️

scientific article published on April 25, 2012

Akt/PKB Controls the Activity‐Dependent Bulk Endocytosis of Synaptic Vesicles ⬇️

scientific article published on April 29, 2012

Altered synaptobrevin-II trafficking in neurons expressing a synaptophysin mutation associated with a severe neurodevelopmental disorder.

scientific article published on 5 September 2017

An epilepsy-associated SV2A mutation disrupts synaptotagmin-1 expression and activity-dependent trafficking

scientific article published on 24 April 2020

Ba2+ does not support synaptic vesicle retrieval in rat cerebrocortical synaptosomes.

scientific article published in August 1998

Building a better dynasore: the dyngo compounds potently inhibit dynamin and endocytosis

scientific article published on 9 October 2013

Ca2+ Influx Inhibits Dynamin and Arrests Synaptic Vesicle Endocytosis at the Active Zone

scientific article published on 01 February 2000

Calcineurin selectively docks with the dynamin Ixb splice variant to regulate activity-dependent bulk endocytosis

scientific article published on 05 July 2011

Control of synaptic vesicle endocytosis by an extracellular signalling molecule

scientific article published on January 2013

Control of synaptic vesicle release probability via VAMP4 targeting to endolysosomes

Developmental change in the calcium sensor for synaptic vesicle endocytosis in central nerve terminals

scientific article published on July 2005

Differential proteomics analysis of synaptic proteins identifies potential cellular targets and protein mediators of synaptic neuroprotection conferred by the slow Wallerian degeneration (Wlds) gene

scientific article

Dynamin I phosphorylation and the control of synaptic vesicle endocytosis.

scientific article

Dynamin I phosphorylation by GSK3 controls activity-dependent bulk endocytosis of synaptic vesicles.

scientific article

Energetics of cultured neurones and ischaemia ⬇️

scientific article published on November 1, 1994

Enhanced Protein Recovery and Reproducibility from Pull-Down Assays and Immunoprecipitations Using Spin Columns

scientific article published on 01 August 2001

Exocytosis and selective neurite calcium responses in rat cerebellar granule cells during field stimulation.

scientific article

Glutamate exocytosis from cerebellar granule cells: The mechanism of a transition to an L-type Ca2+ channel coupling

scientific article published on 01 August 1995

Glycogen synthase kinase-3.

scientific article

Identification of a human synaptotagmin-1 mutation that perturbs synaptic vesicle cycling

scientific article

Integration of Synaptic Vesicle Cargo Retrieval with Endocytosis at Central Nerve Terminals.

scientific article published on 3 August 2017

Intracellular free Ca2+responses in electrically stimulated cerebellar granule cells

article

Key physiological parameters dictate triggering of activity-dependent bulk endocytosis in hippocampal synapses

scientific article

Mechanisms of synaptic vesicle recycling illuminated by fluorescent dyes.

scientific article

Mitochondrial Calcium Uptake Modulates Synaptic Vesicle Endocytosis in Central Nerve Terminals

scientific article published on 7 December 2015

Modulation of ion gradients and glutamate release in cultured cerebellar granule cells by ouabain

scientific article published on 01 May 1995

Monitoring activity-dependent bulk endocytosis with the genetically-encoded reporter VAMP4-pHluorin

scientific article published on 22 March 2016

Munc18-1 protein molecules move between membrane molecular depots distinct from vesicle docking sites

scientific article published on 6 December 2012

Myristyl Trimethyl Ammonium Bromide and Octadecyl Trimethyl Ammonium Bromide Are Surface-Active Small Molecule Dynamin Inhibitors that Block Endocytosis Mediated by Dynamin I or Dynamin II

scientific article published on 16 August 2007

Phosphatidylinositol 3-Kinase Couples Localised Calcium Influx to Activation of Akt in Central Nerve Terminals

scientific article published on 22 July 2015

Phosphorylation of synaptic vesicle protein 2A at Thr84 by casein kinase 1 family kinases controls the specific retrieval of synaptotagmin-1.

scientific article

Phosphorylation of syndapin I F-BAR domain at two helix-capping motifs regulates membrane tubulation

scientific journal article

Physiological Concentrations of Amyloid Beta Regulate Recycling of Synaptic Vesicles via Alpha7 Acetylcholine Receptor and CDK5/Calcineurin Signaling

scientific article published on 21 July 2017

Presynaptic calcium channels and field-evoked transmitter exocytosis from cultured cerebellar granule cells.

scientific article published in November 1997

Protein phosphorylation is required for endocytosis in nerve terminals: potential role for the dephosphins dynamin I and synaptojanin, but not AP180 or amphiphysin

scientific article published on 01 January 2001

Pyrimidyn compounds: dual-action small molecule pyrimidine-based dynamin inhibitors.

scientific article

Quantitative analysis of synaptic vesicle pool replenishment in cultured cerebellar granule neurons using FM dyes.

scientific article published on 11 November 2011

Regulation of synaptic vesicle recycling by complex formation between intersectin 1 and the clathrin adaptor complex AP2

scientific article

SNAREdinburgh: the molecular mechanisms of exocytosis and endocytosis

scientific article published in August 2001

SYT1-associated neurodevelopmental disorder: a case series

scientific article published on 01 September 2018

Simultaneous monitoring of three key neuronal functions in primary neuronal cultures.

scientific article published on 17 October 2006

Synapsin I-associated phosphatidylinositol 3-kinase mediates synaptic vesicle delivery to the readily releasable pool

scientific article published on 16 May 2003

Synaptic Vesicle Endocytosis and Endosomal Recycling in Central Nerve Terminals: Discrete Trafficking Routes?

scientific article published on 15 July 2014

Synaptic Vesicle Recycling Is Unaffected in the Ts65Dn Mouse Model of Down Syndrome

scientific article (publication date: 2016)

Synaptic vesicle exocytosis and increased cytosolic calcium are both necessary but not sufficient for activity-dependent bulk endocytosis

scientific article published on 14 May 2015

Synaptic vesicle generation from activity-dependent bulk endosomes requires a dephosphorylation-dependent dynamin-syndapin interaction

scientific article published on 17 October 2019

Synaptic vesicle generation from activity-dependent bulk endosomes requires calcium and calcineurin.

scientific article published on February 2013

Synaptic vesicle generation from central nerve terminal endosomes

scientific article

Synaptic vesicle recycling in cultured cerebellar granule cells: role of vesicular acidification and refilling.

scientific article

Synaptophysin is required for synaptobrevin retrieval during synaptic vesicle endocytosis

scientific article

Synaptophysin sustains presynaptic performance by preserving vesicular synaptobrevin-II levels

scientific article published on 16 July 2019

Syndapin I is the phosphorylation-regulated dynamin I partner in synaptic vesicle endocytosis

scientific article

The Best Things Come in Small Packages– Vesicular Delivery of Weak Base Antipsychotics

scientific article published on 01 June 2012

The Role of GSK3 in Presynaptic Function ⬇️

scientific article published on March 14, 2011

The Sybtraps: control of synaptobrevin traffic by synaptophysin, α-synuclein and AP-180.

scientific article published on 16 December 2013

The Synaptic Vesicle Cycle Revisited: New Insights into the Modes and Mechanisms

scientific article published on 01 October 2019

The calcium channel coupled to the exocytosis of l-glutamate from cerebellar granule cells is inhibited by the spider toxin, Aga-GI

scientific article published on 01 November 1993

The iTRAPs: Guardians of Synaptic Vesicle Cargo Retrieval During Endocytosis

scientific article

The phospho-dependent dynamin-syndapin interaction triggers activity-dependent bulk endocytosis of synaptic vesicles

scientific article

Transmitter exocytosis in cultured cerebellar granule cells stimulated with an applied electrical field.

scientific article published in August 1996

Two Mechanisms of Synaptic Vesicle Recycling in Rat Brain Nerve Terminals

scientific article published on 01 October 2000

Use of FM1-43 and other derivatives to investigate neuronal function.

scientific article published on April 2008

Using FM Dyes to Monitor Clathrin-Mediated Endocytosis in Primary Neuronal Culture

scientific article published on 01 January 2018

VAMP4 Is an Essential Cargo Molecule for Activity-Dependent Bulk Endocytosis

scientific article

X-linked intellectual disability-associated mutations in synaptophysin disrupt synaptobrevin II retrieval

scientific article published on August 2013

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