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List of works by Zsolt Radak

8-Oxo-7,8-dihydroguanine: links to gene expression, aging, and defense against oxidative stress

scientific article

8-Oxoguanine DNA glycosylase-1 links DNA repair to cellular signaling via the activation of the small GTPase Rac1.

scientific article published on 21 April 2013

8-Oxoguanine DNA glycosylase-1-mediated DNA repair is associated with Rho GTPase activation and α-smooth muscle actin polymerization.

scientific article

8-Oxoguanine DNA glycosylase1-driven DNA repair-A paradoxical role in lung aging.

scientific article published on 21 June 2016

8-Oxoguanosine and uracil repair of nuclear and mitochondrial DNA in red and white skeletal muscle of exercise-trained old rats.

scientific article published on 4 January 2007

8-oxoguanine DNA glycosylase-1 augments proinflammatory gene expression by facilitating the recruitment of site-specific transcription factors

scientific article published on 31 January 2014

A comparison of chronic AICAR treatment-induced metabolic adaptations in red and white muscles of rats.

scientific article published on 12 November 2014

A period of anaerobic exercise increases the accumulation of reactive carbonyl derivatives in the lungs of rats

scientific article published on 01 February 1998

Activation of Ras Signaling Pathway by 8-Oxoguanine DNA Glycosylase Bound to Its Excision Product, 8-Oxoguanine ⬇️

scientific article published on May 8, 2012

Aerobic endurance capacity affects spatial memory and SIRT1 is a potent modulator of 8-oxoguanine repair.

scientific article published on 22 August 2013

Age-associated declines in mitochondrial biogenesis and protein quality control factors are minimized by exercise training

scientific journal article

Age-associated neurodegeneration and oxidative damage to lipids, proteins and DNA.

scientific article published on August 2011

Age-dependent changes in 8-oxoguanine-DNA glycosylase activity are modulated by adaptive responses to physical exercise in human skeletal muscle.

scientific article published on 15 April 2011

Aging and exercise affect the level of protein acetylation and SIRT1 activity in cerebellum of male rats.

scientific article published on 14 May 2010

Alzheimer's Disease Mouse as a Model of Testis Degeneration

scientific article published on 10 August 2020

Are the neuroprotective effects of estradiol and physical exercise comparable during ageing in female rats? ⬇️

scientific article published on June 22, 2012

Attenuation of the development of murine solid leukemia tumor by physical exercise.

scientific article published in February 2002

Beneficial biochemical outcomes of late-onset dietary restriction in rodents.

scientific article published on April 2007

Biochemical identification of a hydroperoxide derivative of the free 8-oxo-7,8-dihydroguanine base

scientific article published on December 2011

Carbonylated proteins in aging and exercise: immunoblot approaches.

scientific article

Cardioprotective effects of voluntary exercise in a rat model: role of matrix metalloproteinase-2.

scientific article

Changes in urine 8-hydroxydeoxyguanosine levels of super-marathon runners during a four-day race period

scientific article published on 01 March 2000

Combined exercise and insulin-like growth factor-1 supplementation induces neurogenesis in old rats, but do not attenuate age-associated DNA damage

scientific article published on 25 August 2011

Correlation of the microbiota and intestinal mucosa in the pathophysiology and treatment of irritable bowel, irritable eye, and irritable mind syndrome

scientific article

Correlations of psycho-physiological parameters influencing the physical fitness of aged women.

scientific article published in December 2014

Decreased serum brain-derived neurotrophic factor in trained men

scientific article published on 26 March 2008

Differentiation-Associated Downregulation of Poly(ADP-Ribose) Polymerase-1 Expression in Myoblasts Serves to Increase Their Resistance to Oxidative Stress.

scientific article published on 28 July 2015

Does exercise reduce brain oxidative stress? A systematic review

scientific article

Down-regulation of 8-oxoguanine DNA glycosylase 1 expression in the airway epithelium ameliorates allergic lung inflammation

scientific article published on 3 November 2012

Eating habits modulate short term memory and epigenetical regulation of brain derived neurotrophic factor in hippocampus of low- and high running capacity rats.

scientific article

Effect of aging and late onset dietary restriction on antioxidant enzymes and proteasome activities, and protein carbonylation of rat skeletal muscle and tendon.

scientific article

Effect of diazepam treatment on metabolic indices in trained and untrained rats.

scientific article published in January 2003

Exercise Increases Markers of Spermatogenesis in Rats Selectively Bred for Low Running Capacity

scientific article published on 10 December 2014

Exercise and hormesis: oxidative stress-related adaptation for successful aging

scientific article published on 01 January 2005

Exercise combined with a probiotics treatment alters the microbiome, but moderately affects signalling pathways in the liver of male APP/PS1 transgenic mice

scientific article published on 18 August 2020

Exercise preconditioning against hydrogen peroxide-induced oxidative damage in proteins of rat myocardium

scientific article published on 01 April 2000

Exercise training increases anabolic and attenuates catabolic and apoptotic processes in aged skeletal muscle of male rats

scientific article

Exercise, oxidants, and antioxidants change the shape of the bell-shaped hormesis curve

scientific article published on 03 March 2017

Exercise-induced oxidative stress: past, present and future.

scientific article published on 19 February 2016

Exogenous nicotinamide supplementation and moderate physical exercise can attenuate the aging process in skeletal muscle of rats

scientific article published on 5 May 2017

High altitude exposure alters gene expression levels of DNA repair enzymes, and modulates fatty acid metabolism by SIRT4 induction in human skeletal muscle.

scientific article published on 21 February 2014

Higher levels of ATGL are associated with exercise-induced enhancement of lipolysis in rat epididymal adipocytes.

scientific article

Hormetic effects of regular exercise in aging: correlation with oxidative stress.

scientific article published on October 2007

Influence of pulsing electromagnetic field therapy on resting blood pressure in aging adults

scientific article published on 01 June 2013

Innate inflammation induced by the 8-oxoguanine DNA glycosylase-1-KRAS-NF-κB pathway

scientific article

Is physical activity an elixir?

scientific article published in May 2013

Long-term exercise treatment reduces oxidative stress in the hippocampus of aging rats

scientific journal article

Lung cancer in smoking patients inversely alters the activity of hOGG1 and hNTH1.

scientific article

Marathon running alters the DNA base excision repair in human skeletal muscle.

scientific article

Mitochondrial biogenesis-associated factors underlie the magnitude of response to aerobic endurance training in rats

scientific journal article

Muscle soreness-induced reduction in force generation is accompanied by increased nitric oxide content and DNA damage in human skeletal muscle

scientific article published on 01 April 1999

Nitric oxide: Is it the cause of muscle soreness? ⬇️

scientific article published on December 28, 2011

Oligomerized grape seed polyphenols attenuate inflammatory changes due to antioxidative properties in coculture of adipocytes and macrophages.

scientific article

Oxidant antioxidants and adaptive responses to exercise

scientific article

Oxidized Guanine Base Lesions Function in 8-Oxoguanine DNA Glycosylase-1-mediated Epigenetic Regulation of Nuclear Factor κB-driven Gene Expression.

scientific article published on 18 October 2016

Oxygen Consumption and Usage During Physical Exercise: The Balance Between Oxidative Stress and ROS-Dependent Adaptive Signaling ⬇️

scientific article published on November 16, 2012

Physical exercise, reactive oxygen species and neuroprotection

scientific article published on 28 January 2016

Pollen-induced oxidative DNA damage response regulates miRNAs controlling allergic inflammation.

scientific article published on 10 August 2017

Protein carbonyl content roughly reflects the unsaturation of lipids in muscle but not in other tissues of stroke-prone spontaneously hypertensive strain (SHRSP) rats fed different fats and oils.

scientific article

Redox-regulating sirtuins in aging, caloric restriction, and exercise.

scientific article published on 20 January 2013

Regular exercise improves cognitive function and decreases oxidative damage in rat brain.

scientific article published in January 2001

Regular exercise reduces 8-oxodG in the nuclear and mitochondrial DNA and modulates the DNA repair activity in the liver of old rats

scientific article published on 03 January 2007

Regular exercise: an effective means to reduce oxidative stress in old rats.

scientific article published in June 2004

Regular training modulates the accumulation of reactive carbonyl derivatives in mitochondrial and cytosolic fractions of rat skeletal muscle

scientific article published on 01 November 2000

Relationship between ventilatory function and age in master athletes and a sedentary reference population

scientific article published on 28 April 2012

Resveratrol attenuates exercise-induced adaptive responses in rats selectively bred for low running performance.

scientific article published on 04 June 2013

Resveratrol enhances exercise training responses in rats selectively bred for high running performance ⬇️

scientific article published on February 17, 2013

SIRT1 may play a crucial role in overload-induced hypertrophy of skeletal muscle.

scientific article

Short-term adenosine monophosphate-activated protein kinase activator 5-aminoimidazole-4-carboxamide-1-β-D-ribofuranoside treatment increases the sirtuin 1 protein expression in skeletal muscle

scientific article published on 01 April 2010

Single Dose Administration of Taheebo Polyphenol Enhances Endurance Capacity in Mice

scientific article published in Scientific Reports

Super-marathon race increases serum and urinary nitrotyrosine and carbonyl levels.

scientific article

Superoxide dismutase derivative reduces oxidative damage in skeletal muscle of rats during exhaustive exercise

scientific article published on 01 July 1995

The beneficial effects of nettle supplementation and exercise on brain lesion and memory in rat.

scientific article published on 13 December 2008

The effect of exercise and oxidant-antioxidant intervention on the levels of neurotrophins and free radicals in spinal cord of rats.

scientific article published on 21 October 2008

The effect of exercise training on oxidative damage of lipids, proteins, and DNA in rat skeletal muscle: evidence for beneficial outcomes

scientific article published on 01 July 1999

The effect of high altitude and caloric restriction on reactive carbonyl derivatives and activity of glutamine synthetase in rat brain ⬇️

scientific article published on January 1, 1998

The effects of aging, physical training, and a single bout of exercise on mitochondrial protein expression in human skeletal muscle.

scientific article published on 17 March 2012

The effects of cocoa supplementation, caloric restriction, and regular exercise, on oxidative stress markers of brain and memory in the rat model ⬇️

scientific article published on February 16, 2013

The effects of moderate, strenuous, and overtraining on oxidative stress markers and DNA repair in rat liver.

scientific article published in April 2005

The effects of statin medications on aerobic exercise capacity and training adaptations.

scientific article

The effects of training and detraining on memory, neurotrophins and oxidative stress markers in rat brain.

scientific article published on 27 March 2006

The rate of training response to aerobic exercise affects brain function of rats.

scientific article

The redox-associated adaptive response of brain to physical exercise ⬇️

scientific article published on October 18, 2013

The role of 8-oxoguanine DNA glycosylase-1 in inflammation

scientific article

Traumatic brain injury: oxidative stress and neuroprotection.

scientific article published on 10 May 2013

Voluntary exercise may engage proteasome function to benefit the brain after trauma.

scientific article

Whole transcriptome analysis reveals a role for OGG1-initiated DNA repair signaling in airway remodeling

scientific article published on 14 July 2015

Whole transcriptome analysis reveals an 8-oxoguanine DNA glycosylase-1-driven DNA repair-dependent gene expression linked to essential biological processes

scientific article

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